Identifiers and Description

Gene Model Identifier

TTHERM_01048090

Standard Name

SMC1 (Structural Maintenance of Chromosomes 1)

Aliases

PreTt17667 | 211.m00035 | 3758.m00207

Description

SMC1 SMC family carboxy-terminal domain protein; SMC family; C-terminal domain containing protein; subunit of cohesin complex

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• chromosome (IEA) | GO:0005694
• cohesin complex (IDA) | GO:0008278

Molecular Function

• ATP binding (IEA) | GO:0005524

Biological Process

• chromosome segregation (IDA) | GO:0007059

Domains

• ( TIGR01885 ) ornithine--oxo-acid transaminase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_20430.1	9.997093137033517e-262
	Description: SMC family domain-containing protein (1298 aa)
Oxytricha	Contig18105.0.g52	2.998863950472602e-38
	Description: RecF/RecN/SMC N terminal domain
DictyBase	DDB_G0291752	2.999534586690157e-23
	Description: smc1 on chromosome: 6 position 688164 to 692478
SGD	YFL008W	1.9994498063102785e-22
	Description: SMC1 Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure
WormBase	WBGene00001860	2.9990241513684e-21
	Description: locus:him-1 status:Confirmed UniProt:O01789 protein_id:CCD69832.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:29948142: Ali EI, Loidl J, Howard-Till RA (2018) A streamlined cohesin apparatus is sufficient for mitosis and meiosis in the protist Tetrahymena. Chromosoma ( ):
2. Ref:23555314: Howard-Till RA, Lukaszewicz A, Novatchkova M, Loidl J (2013) A single cohesin complex performs mitotic and meiotic functions in the protist tetrahymena. PLoS genetics 9(3):e1003418

Sequences

>TTHERM_01048090(coding)
ATGAATATCTACTTTATAGAGGTTGAAAATTTTAAATCATTTAGAGGTAAGCATTAAATT
GGACCTTTTACTTAAATGACTGGTATAATAGGTCCTAATGGCTGTGGTAAAAGTAATATA
GTTGATGCTTTGACTTTTGCTTTCAATATAGAAAATGCAAGAAATCATCATCCAATTAGT
AGTATAACTTAGCAATCAAAACCTGATATGTGCTCAGTAGAGGTAGTATTATAAGATAAG
CGTTAAAAAATATCCTTTAAAAAAACCTAAAACAGAAAAAAATAAATAACATTTTACATG
AATAACAACATATTAAATCAAGATTAATATTTAGAATAGCTTAAAAAATATAATATTGGT
CCATAATCTTTTATGCTTTAAGGCGAAACTGATAAACTCATTAAGAAAAGTCCAGAAGAA
CTATCAGAAATCATTGAAAAAGCATGCGGAAGTCTTTAATATAAAAAGGAATATGATGAG
TTAAATCAATAAATAAAATCAATCAATGATGAGACCATTAAAATTATTTCAGAATAAAAG
AATCTAAAAAAAGAGGATTAAAAATTAAGAAGCATAAGTGAATAGAATGAGAAATATGAA
TCCTTAAATGAAGAAATAAAATAAATAGAAGTCAAAATCGAATAAGCTAACTTCTTTTAA
ATTGACAGCAGCATTTTATAAGAAATGAAAGCATTATCAACCACACAAAATAAATTAGAT
GAAAGAAAAACAGAAGAAGGAGCAATCAAATAGAAAATTTAGTAGAACAATATTAAAATT
AAAAATTTGCAAAAAGAACAGTCTAAAAAAGAGAAAGAAAGAGAGTAAATTAAGCAATAA
ATTAGAGAACTTTAGGAGTAATTGGAATAAGAGGAGGATTAAGTTAAGAATGCTAAAAGT
TTTTCAGAGAATGCTAAATTGCAAAAAAGTTTCTAAGATCAAATAAAAGATATTAATGAT
AGCTTGGCAAAATTAAATGGTCAATTGAGAAAAGAAGAGTCTATTTTGAATGATATGCAA
TCGAAAGAATCCTAAAAAAGCAAAATTGAGAATAAAAAATTGAAAGACAACTATGAAGAG
TATCAAGAATTAGTAAGAGTGTGCAATTCATAAACTTTGAACTTAGAACTTGAGAGTAAA
AAGCTTGCAAATGATATGAATAATGCTCTTTCTCAATTAAAAGTGTCAATAGAGGCTTAG
TCTAAATAAAATAATCACATTGAAGAGCTTGAAACAAAAATTAATGAGGCAAAGACTAAT
TAAATTTCTAAATAAGGAGAACTTTAGTAAAAATAATAGGAAATCTCTTCAATTAAGTAA
GAATTAATAGAATTAGAAAATCAAAGAAAAGATAATGTTCTCAAGATGGAAAACATTTAA
AAGGATTTATCAGTACTATTATCAAATAAGCTTTCCTTAGAGTATGAGTTAGAGTAAATG
GAAGAAATTAGAAATTAAAATAAAGTGTATAGAGAACTTCATAAATTTAAAGGATTTTAT
GGATAATTTTCTGAATTAATTAGGAATAATTCAAATAAATCCTATGATTTGTCTATAAAA
ATAGCTTTAGGTTCATTCCTATCATGCTTGGTTGTGGATAGTCCTTAAACAGCCTCTCTA
GTAAATGTTACCTTAGCCTCATAAGGATTAGCAAGAGATGTTATGATTTTATAAAATTTA
CCGAACTCAGATGATGATTTAGTAAAGGCCAGAATTGGTAATTTAGGTGAACTAGCTACA
TCTCTTGTTGATATTGATGAAAGATCATCTAAATATGAAGAAAATCCAGAATTAAAGGCA
AAAATAGCAGACACATTAAAATACTTATTAAGAGGCAAAGTTATTTGCGAAAACACAGAA
AAAGCTTTTTAGTTGAGAAATCGTAAAATTAAAGAAGTTTATTAGATTATTACAAAAGAT
GGAGACATTGTGACCAGCGGAAGTATTTAAATTTCTAGTAGTGACAAAGAGAAATACTCT
AAAAAGGATTTAGGAACAGAATAAAATATTTAGAACCTACAAAAAAAGATCTAAAATGAA
GAAAAATAAATAGATAAGAAGATGGTAGAGCTAGAATCTATTAAAAATTCAGACACTGAA
AAAAAATACAATAAATTAATAGAATAGTTACAAGTTCGTGAATCTTCAATCGAAATAACA
AATACAGAATTAACTTCTATTTAAGAGAAAATCAAAAAACTTGAAGAAAAAAAACAGCAA
ATAAAAAATGTAATTGCAAAAAGCTTAGAAATTATAAATCTTGAAAACACTGTGAAAGAA
ATTGAGAAAAGGTTGCAAGATACCTAAGAAAAGATTGACAAAAAGAGAAGCGAAGTTTAT
GATCCTTTTTGTAAAAAATATAAAATTGATATTAAAGAATTAATTTCTGTAAACGCCGAT
ACAGTAGAAAGAATATTCAAAAATATTGAGAAATAATAAACTAAAGTACAAGATATTAAT
AATTCTATTAAGTCTCATTAAGAAAAGCTTGATAATATTATTAAGGCATAAGAAAAATAC
AATGAAAATAAAAAAAACTTCGAAGAGTTACTTGAACAATTTAAAAATGTTTCTACCAAA
ATTTAAAACACTAAAAACGAGTTAGACAACAAATACAAGAAAGCTATATCTGAAGTATAA
TAGTTTGAAAAGGAAATTTAAGAAATAAATTAAGAAAATGAAAGCAGCTACTAGCTGTTA
ATTTAGTAACCAAATCAACTTAGAAAAGATATAATTCAAATAAAGCACTCAATAGGGTAA
TTAATAGATAAAAAAGAAACTCTTTGGCAAGAATGCTAATTGAAGTAAATAGAATTTAAA
GACTCGTCTAAAATGAATAATAAAGCCTAAAATGATTCTATGATGGAAGAGTTAGATAGT
AAGAGTAAAAGTTAATCCTCATAGCAAGATGATATTGAGTCTTAAGATGAAAAAGAATAA
ATACAAACTCTTTCAAAAGATTTTACTAAGTCTCTTAAACAATATACACAGGCTTTGTCA
TAAATAAATGATGTAAAGCTATAGGAATCTCTAAATAAATTTAGTGAAATTGAAATGCTT
AACTACTTTATGCTTTTTAAAGATAAAAGCTAATTTTAGAAGAAAAGGACTGTTCGCCAA
TAATAAATGGTAGATGAAACAAAAGAGAGTCTTCTAACTTAGTTATTGGAGACTGTAGAT
ATAGGCTCTTTGTTAAATTATTAAAATCGTCTAGTTGACCGCTTAGAAGAATTACGTAAA
AAAATTGAAGAATATGCTTCAAAAGACCTTGCTGAAGGACTAATGGGTGCAACTGTTACA
AGTGAAGAAATGAAAGTAAAAAAAGAAAATTTAAAAAATCGCTAAGCAGAATTAGTGTCT
GAAAAAAAGAAGGCAGAAGAAGATCTCAAAAATATCAAGAAATTACGTAAAGAAAAATTT
GATGAATTCTTTAAAGAAGTTTAAAGTTAAGTAAAAATATATTATGGTGAATTAACTAAA
CTCAAAGGAAAACATTAAGGCTAAAAAGGAAATGCTGATTTAACAGTTAGTGATGAAGAA
GAAAAGTATAAAGGTGGAATAAATTACTTTTGTTGCCCTCCTAAAAAAGCTTATGCTTTA
AATCCAGAAAAAGAGTTAAGTGGAGGTGAGAAGACTTTGGCACAAATAGCTCTTTTCCTT
GCTATTGCAAAAGATTCTCCTTTTTTGATATTAGATGAGTCAGAAGCTGCTCTTGATTCA
TCAAATACATAGAATGTGATTGAAACATTTAGAAACCTAATTACAAAACAATAAAAACTA
ATAGTTTCTCACAATTAAGAAGTCTATTCATAATGTGATAGCTTGATAGGAACAACCTTT
AATAGATACACTGATACATCATTCACCTTATCTTTAAATTTAAAAGCATGA

>TTHERM_01048090(gene)
ATGAATATCTACTTTATAGAGGTTGAAAATTTTAAATCATTTAGAGGTAAGCATTAAATT
GGACCTTTTACTTAAATGACTGGTATAATAGGTCCTAATGGCTGTGGTAAAAGTAATATA
GTTGATGCTTTGACTTTTGCTTTCAATATAGAAAATGCAAGAAATCATCATCCAATTAGT
AGTATAACTTAGCAATCAAAACCTGATATGTGCTCAGTAGAGGTAGTATTATAAGATAAG
CGTTAAAAAATATCCTTTAAAAAAACCTAAAACAGAAAAAAATAAATAACATTTTACATG
AATAACAACATATTAAATCAAGATTAATATTTAGAATAGCTTAAAAAATATAATATTGGT
AAATAATAGAATATTTATAGATTGGCAATTTATTTAATTATTTATATAGGTCCATAATCT
TTTATGCTTTAAGGCGAAACTGATAAACTCATTAAGAAAAGTCCAGAAGAACTATCAGAA
ATCATTGAAAAAGCATGCGGAAGTCTTTAATATAAAAAGGAATATGATGAGTTAAATCAA
TAAATAAAATCAATCAATGATGAGACCATTAAAATTATTTCAGAATAAAAGAATCTAAAA
AAAGAGGATTAAAAATTAAGAAGCATAAGTGAATAGAATGAGAAATATGAATCCTTAAAT
GAAGAAATAAAATAAATAGAAGTCAAAATCGAATAAGCTAACTTCTTTTAAATTGACAGC
AGCATTTTATAAGAAATGAAAGCATTATCAACCACACAAAATAAATTAGATGAAAGAAAA
ACAGAAGAAGGAGCAATCAAATAGAAAATTTAGTAGAACAATATTGTAAAATTATTTTTT
AAAAGCAAATAAATCTAAATTTTAATTTAAAATATTAGAAAATTAAAAATTTGCAAAAAG
AACAGTCTAAAAAAGAGAAAGAAAGAGAGTAAATTAAGCAATAAATTAGAGAACTTTAGG
AGTAATTGGAATAAGAGGAGGATTAAGTTAAGAATGCTAAAAGTTTTTCAGAGAATGCTA
AATTGCAAAAAAGTTTCTAAGATCAAATAAAAGATATTAATGATAGCTTGGCAAAATTAA
ATGGTCAATTGAGAAAAGAAGAGTCTATTTTGAATGATATGCAATCGAAAGAATCCTAAA
AAAGCAAAATTGAGAATAAAAAATTGAAAGACAACTATGAAGAGTATCAAGAATTAGTAA
GAGTGTGCAATTCATAAACTTTGAACTTAGAACTTGAGAGTAAAAAGCTTGCAAATGATA
TGAATAATGCTCTTTCTCAATTAAAAGTGTCAATAGAGGCTTAGTCTAAATAAAATAATC
ACATTGAAGAGCTTGAAACAAAAATTAATGAGGCAAAGACTAATTAAATTTCTAAATAAG
GAGAACTTTAGTAAAAATAATAGGAAATCTCTTCAATTAAGTAAGAATTAATAGAATTAG
AAAATCAAAGAAAAGATAATGTTCTCAAGATGGAAAACATTTAAAAGGATTTATCAGTAC
TATTATCAAATAAGCTTTCCTTGTAATATTTTCAATTCATTTTTAGTTTTTAAATTTATT
TTATTTTTATAAAAGAGAGTATGAGTTAGAGTAAATGGAAGAAATTAGAAATTAAAATAA
AGTGTATAGAGAACTTCATAAATTTAAAGGATTTTATGGATAATTTTCTGAATTAATTAG
GAATAATTCAAATAAATCCTATGATTTGTCTATAAAAATAGCTTTAGGTTCATTCCTATC
ATGCTTGGTAATTATTTATTTTAATTTAAGGATAAATTAAAATTTTTTAAAATAACAGGT
TGTGGATAGTCCTTAAACAGCCTCTCTAGTAAATGTTACCTTAGCCTCATAAGGATTAGT
AATTAAATAATTTTTAAGAGTAAGATTTGAAGATAATTTTTTATAAAATTTTTAAGGCAA
GAGATGTTATGATTTTATAAAATTTACCGAACTCAGATGATGATTTAGTAAAGGCCAGAA
TTGGTAATTTAGGTGAACTAGCTACATCTCTTGTTGATATTGATGAAAGATCATCTAAAT
ATGAAGAAAATCCAGAATTAAAGGCAAAAATAGCAGACACATTAAAATACTTATTAAGAG
GCAAAGTTATTTGCGAAAACACAGAAAAAGCTTTTTAGTTGAGAAATCGTAAAATTAAAG
AAGTTTATTAGATTATTACAAAAGATGGAGACATTGTGACCAGCGGAAGTATTTAAATTT
CTAGTAGTGACAAAGAGAAATACTCTAAAAAGGATTTAGGAACAGAATAAAATATTTAGA
ACCTACAAAAAAAGATCTAAAATGAAGAAAAATAAATAGATAAGAAGATGGTAGAGCTAG
AATCTATTAAAAATTCAGACACTGAAAAAAAATACAATAAATTAATAGAATAGTTACAAG
TTCGTGAATCTTCAATCGAAATAACAAATACAGTAAGTAGCTTTTATTTAATAAATTTTA
AGTTTAATTAAATAATTTTTTTTAAAAGGAATTAACTTCTATTTAAGAGAAAATCAAAAA
ACTTGAAGAAAAAAAACAGCAAATAAAAAATGTAATTGCAAAAAGCTTAGAAATTATAAA
TCTTGAAAACACTGTGAAAGAAATTGAGAAAAGGTTGCAAGATACCTAAGAAAAGATTGA
CAAAAAGAGAAGCGAAGTTTATGATCCTTTTTGTAAAAAATATAAAATTGATATTAAAGA
ATTAATTTCTGTAAACGCCGATACAGTAGAAAGAATATTCAAAAATATTGAGAAATAATA
AACTAAAGTACAAGATATTAATAATTCTATTAAGTCTCATTAAGAAAAGCTTGATAATAT
TATTAAGGCATAAGAAAAATACAATGAAAATAAAAAAAACTTCGAAGAGTTACTTGAACA
ATTTAAAAATGTTTCTACCAAAATTTAAAACACTAAAAACGAGTTAGACAACAAATACAA
GAAAGCTATATCTGAAGTATAATAGTTTGAAAAGGAAATTTAAGAAATAAATTAAGAAAA
TGAAAGCAGCTACTAGCTGTTAATTTAGTAACCAAATCAACTTAGAAAAGATATAATTCA
AATAAAGCACTCAATAGGGTAATTAATAGATAAAAAAGAAACTCTTTGGCAAGAATGCTA
ATTGAAGTAAATAGAATTTAAAGACTCGTCTAAAATGAATAATAAAGCCTAAAATGATTC
TATGATGGAAGAGTTAGATAGTAAGAGTAAAAGTTAATCCTCATAGCAAGATGATATTGA
GTCTTAAGATGAAAAAGAATAAATACAAACTCTTTCAAAAGATTTTACTAAGTCTCTTAA
ACAATATACACAGGCTTTGTCATAAATAAATGATGTAAAGCTATAGGAATCTCTAAATAA
ATTTAGTGAAATTGAAATGCTTAACTACTTTATGCTTTTTAAAGATAAAAGCTAATTTTA
GAAGAAAAGGACTGTTCGCCAATAATAAATGGTAGATGAAACAAAAGAGAGTCTTCTAAC
TTAGTTATTGGAGACTGTAGATATAGGCTCTTTGTTAAATTATTAAAATCGTCTAGTTGA
CCGCTTAGAAGAATTACGTAAAAAAATTGAAGAATATGCTTCAAAAGACCTTGCTGAAGG
ACTAATGGGTGCAACTGTTACAAGTGAAGAAATGAAAGTAAAAAAAGAAAATTTAAAAAA
TCGCTAAGCAGAATTAGTGTCTGAAAAAAAGAAGGCAGAAGAAGATCTCAAAAATATCAA
GAAATTACGTAAAGAAAAATTTGATGAATTCTTTAAAGAAGTTTAAAGTTAAGTAAAAAT
ATATTATGGTGAATTAACTAAACTCAAAGGAAAACATTAAGGCTAAAAAGGAAATGCTGA
TTTAACAGTTAGTGATGAAGAAGAAAAGTATAAAGGTGGAATAAATTACTTTTGTTGCCC
TCCTAAAAAAGCTTATGCTTTAAATCCAGAAAAAGAGTTAAGTGGAGGTGAGAAGACTTT
GGCACAAATAGCTCTTTTCCTTGCTATTGCAAAAGATTCTCCTTTTTTGATATTAGATGA
GTCAGAAGCTGCTCTTGATTCATCAAATACATAGAATGTGATTGAAACATTTAGAAACCT
AATTACAAAACAATAAAAACTAATAGTTTCTCACAATTAAGAAGTCTATTCATAATGTGA
TAGCTTGATAGGAACAACCTTTAATAGATACACTGATACATCATTCACCTTATCTTTAAA
TTTAAAAGCATGA

>TTHERM_01048090(protein)
MNIYFIEVENFKSFRGKHQIGPFTQMTGIIGPNGCGKSNIVDALTFAFNIENARNHHPIS
SITQQSKPDMCSVEVVLQDKRQKISFKKTQNRKKQITFYMNNNILNQDQYLEQLKKYNIG
PQSFMLQGETDKLIKKSPEELSEIIEKACGSLQYKKEYDELNQQIKSINDETIKIISEQK
NLKKEDQKLRSISEQNEKYESLNEEIKQIEVKIEQANFFQIDSSILQEMKALSTTQNKLD
ERKTEEGAIKQKIQQNNIKIKNLQKEQSKKEKEREQIKQQIRELQEQLEQEEDQVKNAKS
FSENAKLQKSFQDQIKDINDSLAKLNGQLRKEESILNDMQSKESQKSKIENKKLKDNYEE
YQELVRVCNSQTLNLELESKKLANDMNNALSQLKVSIEAQSKQNNHIEELETKINEAKTN
QISKQGELQQKQQEISSIKQELIELENQRKDNVLKMENIQKDLSVLLSNKLSLEYELEQM
EEIRNQNKVYRELHKFKGFYGQFSELIRNNSNKSYDLSIKIALGSFLSCLVVDSPQTASL
VNVTLASQGLARDVMILQNLPNSDDDLVKARIGNLGELATSLVDIDERSSKYEENPELKA
KIADTLKYLLRGKVICENTEKAFQLRNRKIKEVYQIITKDGDIVTSGSIQISSSDKEKYS
KKDLGTEQNIQNLQKKIQNEEKQIDKKMVELESIKNSDTEKKYNKLIEQLQVRESSIEIT
NTELTSIQEKIKKLEEKKQQIKNVIAKSLEIINLENTVKEIEKRLQDTQEKIDKKRSEVY
DPFCKKYKIDIKELISVNADTVERIFKNIEKQQTKVQDINNSIKSHQEKLDNIIKAQEKY
NENKKNFEELLEQFKNVSTKIQNTKNELDNKYKKAISEVQQFEKEIQEINQENESSYQLL
IQQPNQLRKDIIQIKHSIGQLIDKKETLWQECQLKQIEFKDSSKMNNKAQNDSMMEELDS
KSKSQSSQQDDIESQDEKEQIQTLSKDFTKSLKQYTQALSQINDVKLQESLNKFSEIEML
NYFMLFKDKSQFQKKRTVRQQQMVDETKESLLTQLLETVDIGSLLNYQNRLVDRLEELRK
KIEEYASKDLAEGLMGATVTSEEMKVKKENLKNRQAELVSEKKKAEEDLKNIKKLRKEKF
DEFFKEVQSQVKIYYGELTKLKGKHQGQKGNADLTVSDEEEKYKGGINYFCCPPKKAYAL
NPEKELSGGEKTLAQIALFLAIAKDSPFLILDESEAALDSSNTQNVIETFRNLITKQQKL
IVSHNQEVYSQCDSLIGTTFNRYTDTSFTLSLNLKA