Identifiers and Description

Gene Model Identifier

TTHERM_00190950

Standard Name

ACT1 (ACTin 1)

Aliases

actin | PreTt08746 | 15.m00457 | 3697.m00168

Description

ACT1 macronuclear actin; Actin; structural protein; monomeric subunits of the actin protein (G-actin) polymerize to form structural filiaments (F-actin); localized to the cleavage forrow during cytokinesis

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• aralkylamine N-acetyltransferase activity (IMP) | GO:0004059 | Ref:16524910
• lipid kinase activity (IMP) | GO:0001727 | Ref:14733431
• neutral L-amino acid transmembrane transporter activity (IEP) | GO:0015175 | Ref:3323192
• peptide transporter activity (IMP) | GO:0015197 | Ref:16524910

Biological Process

• negative regulation by symbiont of host cell cycle (IDA) | GO:0044072 | Ref:3323192
• negative regulation of fast-twitch skeletal muscle fiber contraction (IDA) | GO:0031447 | Ref:3323192
• oligosaccharide biosynthetic process (IDA) | GO:0009312 | Ref:14733431
• post-embryonic ectodermal digestive tract morphogenesis (IDA) | GO:0048614 | Ref:3323192
• pyrimidine ribonucleoside triphosphate metabolic process (IDA) | GO:0009208 | Ref:14733431
• ribonucleotide metabolic process (TAS) | GO:0009259 | Ref:14733431

Domains

• ( PF00022 ) Actin

Gene Expression Profile

Tetrahymena Stock Center

• ( SD01796 ) ACT1 KO homozygous in mic, heterokaryon
• ( SD01797 ) ACT1 with neo3 inserted at Sfu1 site
• ( SD01798 ) ACT1 with neo3 inserted at Sfu1 site

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_32251	0
	Description: None
WormBase	WBGene00000066	9.997093137033517e-262
	Description: locus:act-4 Actin-4 status:Confirmed UniProt:P10986 protein_id:CCD83476.1
Tetrahymena borealis	EI9_06202.1	9.997093137033517e-262
	Description: actin, macronuclear (377 aa)
DictyBase	DDB_G0275023	9.997093137033517e-262
	Description: act22 on chromosome: 2 position 5343575 to 5344705
Oxytricha	Contig4562.0.g74	9.997093137033517e-262
	Description: Actin
SGD	YFL039C	9.997093137033517e-262
	Description: ACT1 Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16524910: Williams NE, Tsao CC, Bowen J, Hehman GL, Williams RJ, Frankel J (2006) The actin gene ACT1 is required for phagocytosis, motility, and cell separation of Tetrahymena thermophila. Eukaryotic cell 5(3):555-67
2. Ref:16593729: Cupples CG, Pearlman RE (1986) Isolation and characterization of the actin gene from Tetrahymena thermophila. Proceedings of the National Academy of Sciences of the United States of America 83(14):5160-4

Sequences

>TTHERM_00190950(coding)
ATGGCTGAAAGTGAATCCCCCGCTATTGTTATTGATAACGGTTCCGGTATGTGCAAGGCT
GGTATTGCTGGTGACGATGCTCCCAGAGCCGCCTTCCCCTCCATTGTCGGTAGACCCAAA
ATGCCTGGTATCATGGTCGGTATGGATCAAAAGGAATGCTACGTTGGTGAAGAAGCCCAA
GCCAAGAGAGGTGTTTTGAATTTGAAATATCCCATTGAACACGGTATTGTCACCGATTAC
GATGATATGGAAAAGATCTGGCATCACTGCTTCTACAATGAACTCAGAGTTACCCCTGAA
GAACACCCCTGCTTACTTACTGAAGCTCCCCAAAACCCCAAGTTGAACAGAGAAAAGATG
ACCAAGACCATGTTCGAAACTTTCAACGTTCCCTCCTTCTACGTTGCCATCCAAGCCGTT
CTTTCCCTCTACGCTTCCGGTAGAACCACTGGTATCGTCGTTGACTCTGGTGATGGTGTT
ACCCACACTGTTCCCATCTATGAAGGTTACGCTCTTCCTCACGCCATCTTGAGAATCGAT
TTGGCTGGTAGAGACTTAACTGAATACTGCATGAAGCTCCTCTACGAAATTGGTTTGAAC
TTCTCTTCCACTGCCGAAAGAGAAATCATCAGAGATATCAAGGAAAAGCTCTGCTACGTC
GCTATCGACTACGAAGCTGAATTAAAGGCTTACAAGGAATCCTCCTAAAACGATAAATCT
TACGAATTACCCGATGGTAACACCATTACCGTCCAAGACTAGAGATTCAGATGCCCTGAA
CTCCTCTTCAAGCCTGCCTTCATCGGTAAGGAATTCCCTGGTATCCACGAACTTACCTTC
AACTCTATCATGAAGTGTGATGTCGATGTCAGAAAGGATCTTTACAACAACATCGTCCTC
TCTGGTGGTACCACTATGTTCCCTGGTATTGCTGAAAGACTTTCTAAGGAAGTTAGCGCT
CTTGCTCCTTCTTCCATGAAGATTAAGGTTGTTGCTCCTCCTGAGAGAAGATACTCTGTC
TGGATTGGTGGTTCCATTCTTTCCTCTCTTTCTACCTTCCAAACTATGTGGATTACTAAG
GCTGAATATGATGAATCTGGTCCTTCCATCGTCCACAGAAAGTGCTTCTGA

>TTHERM_00190950(gene)
ATGGCTGAAAGTGAATCCCCCGCTATTGTTATTGATAACGGTTCCGGTATGTGCAAGGCT
GGTATTGCTGGTGACGATGCTCCCAGAGCCGCCTTCCCCTCCATTGTCGGTAGACCCAAA
ATGCCTGGTATCATGGTCGGTATGGATCAAAAGGAATGCTACGTTGGTGAAGAAGCCCAA
GCCAAGAGAGGTGTTTTGAATTTGAAATATCCCATTGAACACGGTATTGTCACCGATTAC
GATGATATGGAAAAGATCTGGCATCACTGCTTCTACAATGAACTCAGAGTTACCCCTGAA
GAACACCCCTGCTTACTTACTGAAGCTCCCCAAAACCCCAAGTTGAACAGAGAAAAGATG
ACCAAGACCATGTTCGAAACTTTCAACGTTCCCTCCTTCTACGTTGCCATCCAAGCCGTT
CTTTCCCTCTACGCTTCCGGTAGAACCACTGGTATCGTCGTTGACTCTGGTGATGGTGTT
ACCCACACTGTTCCCATCTATGAAGGTTACGCTCTTCCTCACGCCATCTTGAGAATCGAT
TTGGCTGGTAGAGACTTAACTGAATACTGCATGAAGCTCCTCTACGAAATTGGTTTGAAC
TTCTCTTCCACTGCCGAAAGAGAAATCATCAGAGATATCAAGGAAAAGCTCTGCTACGTC
GCTATCGACTACGAAGCTGAATTAAAGGCTTACAAGGAATCCTCCTAAAACGATAAATCT
TACGAATTACCCGATGGTAACACCATTACCGTCCAAGACTAGAGATTCAGATGCCCTGAA
CTCCTCTTCAAGCCTGCCTTCATCGGTAAGGAATTCCCTGGTATCCACGAACTTACCTTC
AACTCTATCATGAAGTGTGATGTCGATGTCAGAAAGGATCTTTACAACAACATCGTCCTC
TCTGGTGGTACCACTATGTTCCCTGGTATTGCTGAAAGACTTTCTAAGGAAGTTAGCGCT
CTTGCTCCTTCTTCCATGAAGATTAAGGTTGTTGCTCCTCCTGAGAGAAGATACTCTGTC
TGGATTGGTGGTTCCATTCTTTCCTCTCTTTCTACCTTCCAAACTATGTGGATTACTAAG
GCTGAATATGATGAATCTGGTCCTTCCATCGTCCACAGAAAGTGCTTCTGA

>TTHERM_00190950(protein)
MAESESPAIVIDNGSGMCKAGIAGDDAPRAAFPSIVGRPKMPGIMVGMDQKECYVGEEAQ
AKRGVLNLKYPIEHGIVTDYDDMEKIWHHCFYNELRVTPEEHPCLLTEAPQNPKLNREKM
TKTMFETFNVPSFYVAIQAVLSLYASGRTTGIVVDSGDGVTHTVPIYEGYALPHAILRID
LAGRDLTEYCMKLLYEIGLNFSSTAEREIIRDIKEKLCYVAIDYEAELKAYKESSQNDKS
YELPDGNTITVQDQRFRCPELLFKPAFIGKEFPGIHELTFNSIMKCDVDVRKDLYNNIVL
SGGTTMFPGIAERLSKEVSALAPSSMKIKVVAPPERRYSVWIGGSILSSLSTFQTMWITK
AEYDESGPSIVHRKCF