Identifiers and Description

Gene Model Identifier

TTHERM_00289290

Standard Name

MELG2 (Meiotic nuclear ELonGation 2)

Aliases

PreTt25961 | 26.m00313 | 3688.m00106

Description

MELG2 Required for the elongation of the micronucleus during meiotic prophase; hypothetical protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No. Gene Name(s) Paragraph Text
2348 MELG2 Melg2 protein localizes to the micronucleus during meiotic prophase. In a melg2 deletion mutant, homologous chromosome pairing and bivalent formation are strongly reduced, and the arrangement of centromeres and telomeres within the meiotic nucleus is abnormal.

Associated Literature

  1. Ref:33172984: Tian M, Agreiter C, Loidl J (2020) Spatial constraints on chromosomes are instrumental to meiotic pairing. Journal of cell science 133(22):
  2. Ref:26688337: Kataoka K, Mochizuki K (2015) Phosphorylation of an HP1-like Protein Regulates Heterochromatin Body Assembly for DNA Elimination. Developmental cell 35(6):775-88

Sequences 

>TTHERM_00289290(coding)
ATGCTTATTATGGAAACTCCTCAATTTTCAGCAAAAGATAAAAATGGATAAAATTCACAA
TCTAGTTTTCATTAAGAAATTCTTCGTGCTCCAAAGAAAAATTAAACTAAAAAGACGCTT
TAAATAAAAAAAAATATTATCTTGACATCAGATGTAGCTCATGAGCTCAGAAAAATTAAT
TTTAATGATTCTCCTTTGATGAATTAGTTTATTCTTATGCATGCTAGAGTATTTTAAGAT
AGTAAAACTCCTTAGACTCCCATTAAAAACTATAGAGAAACGCTTCATGATAATAATCTG
TTTGAAGAGAAAGAATCTACAGTGGTTTAGAGTGCAAAGAGAAAATTTATAGAAAGGGAC
TACGATTTAGGGTAATCAGATTAATAGTAGATGATCGATGAAAACATATCTCATACAGAA
AAAAAATTCATAACTTCTGAATGCAAGTAAGAGTATGAGGGTTAGGACTCTAAGAAAAGA
CTGAAGCCTTTACTTCCTTTTAAATCCTCTATCAAGTTTTCCTGTAAAAAAAACAACTCA
TTTTCAGCATTCAATCTTTACAGAGATAAAGAAATACATACAAACATTAGTAGGTTTCCT
TAGAATTTTAAAAAATAAGATCTAGATTATGATTGCTCATCAGAAGAAGAAAGGACGGAA
GATCAAATTATATTTATGTCTGAAGAAATAATTAAAGAAATGCATAATAATTAAAGTTAT
CAATACTAAGACGCAACTAAAAGCTACTTTAATAATTGA



>TTHERM_00289290(gene)
TTGGAATGCTGAAAATTTGATTGATTTTCAGTCATATAATTAATATTCAGCTAATTACCT
TAGATATTTAACAAGATTGCAGTAAACAGAAAAGTAGTTGTTTAAAAATTTTAAATTCTA
TTAAGTAATAATTAAATCTTAGAAATATTGAGTATAATTAATTGCTTCTAAATTTTAGAA
ACCTCTACTTTGTTAGCTAAAATAAAATAGCTTATGCTTATTATGGAAACTCCTCAATTT
TCAGCAAAAGATAAAAATGGATAAAATTCACAATCTAGTTTTCATTAAGAAATTCTTCGT
GCTCCAAAGAAAAATTAAACTAAAAAGACGCTTTAAATAAAAAAAAATATTATCTTGACA
TCAGATGTAGCTCATGAGCTCAGAAAAATTAATTTTAATGATTCTCCTTTGATGAATTAG
TTTATTCTTATGCATGCTAGAGTATTTTAAGATAGTAAAACTCCTTAGACTCCCATTAAA
AACTATAGAGAAACGCTTCATGATAATAATCTGTTTGAAGAGAAAGAATCTACAGTGGTT
TAGAGTGCAAAGAGAAAATTTATAGAAAGGGACTACGATTTAGGGTAATCAGATTAATAG
TAGATGATCGATGAAAACATATCTCATACAGAAAAAAAATTCATAACTTCTGAATGCAAG
TAAGAGTATGAGGGTTAGGACTCTAAGAAAAGACTGAAGCCTTTACTTCCTTTTAAATCC
TCTATCAAGTTTTCCTGTAAAAAAAACAACTCATTTTCAGCATTCAATCTTTACAGAGAT
AAAGAAATACATACAAACATTAGTAGGTTTCCTTAGAATTTTAAAAAATAAGATCTAGAT
TATGATTGCTCATCAGAAGAAGAAAGGACGGAAGATCAAATTATATTTATGTCTGAAGAA
ATAATTAAAGAAATGCATAATAATTAAAGTTATCAATACTAAGACGCAACTAAAAGCTAC
TTTAATAATTGAATGCAATAAGCTTGATTAATAATATTCTTTTAAATTAAAATGATTTGT
TGAAAATTATTAACGAGATAAATAAATATCTATGAACTCAAAGCACTTTACAAAAGAATT
ATAAAAAACTAACAAAAATAAAATTTTAATATAAAGAAATCATAATTAATCACTAAGGCC
AAAATATAATTTTATATAAAAATTTGCACTATAAATTTAAAAGATAATTTAAAAAAATTA
ATTAATATAAAAATTTACTTATAACGTATTATCATTTTATTAATTAATTCTGTTTTGTTT
ATAA



>TTHERM_00289290(protein)
MLIMETPQFSAKDKNGQNSQSSFHQEILRAPKKNQTKKTLQIKKNIILTSDVAHELRKIN
FNDSPLMNQFILMHARVFQDSKTPQTPIKNYRETLHDNNLFEEKESTVVQSAKRKFIERD
YDLGQSDQQQMIDENISHTEKKFITSECKQEYEGQDSKKRLKPLLPFKSSIKFSCKKNNS
FSAFNLYRDKEIHTNISRFPQNFKKQDLDYDCSSEEERTEDQIIFMSEEIIKEMHNNQSY
QYQDATKSYFNN