Identifiers and Description

Gene Model Identifier

TTHERM_00289290

Standard Name

MELG2 (Meiotic nuclear ELonGation 2)

Aliases

PreTt25961 | 26.m00313 | 3688.m00106

Description

Required for the elongation of the micronucleus during meiotic prophase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF09047 ) MEF2 binding

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_09333.1	1.0002335610448659e-38
	Description: hypothetical protein (157 aa)

General Information

No.	Gene Name(s)	Paragraph Text
142	MELG2	Melg2 protein localizes to the micronucleus during meiotic prophase. In a melg2 deletion mutant, homologous chromosome pairing and bivalent formation are strongly reduced, and the arrangement of centromeres and telomeres within the meiotic nucleus is abnormal.

Associated Literature

1. Ref:33172984: Tian M, Agreiter C, Loidl J (2020) Spatial constraints on chromosomes are instrumental to meiotic pairing. Journal of cell science 133(22):
2. Ref:26688337: Kataoka K, Mochizuki K (2015) Phosphorylation of an HP1-like Protein Regulates Heterochromatin Body Assembly for DNA Elimination. Developmental cell 35(6):775-88

Sequences

>TTHERM_00289290(coding)
ATGCTTATTATGGAAACTCCTCAATTTTCAGCAAAAGATAAAAATGGATAAAATTCACAA
TCTAGTTTTCATTAAGAAATTCTTCGTGCTCCAAAGAAAAATTAAACTAAAAAGACGCTT
TAAATAAAAAAAAATATTATCTTGACATCAGATGTAGCTCATGAGCTCAGAAAAATTAAT
TTTAATGATTCTCCTTTGATGAATTAGTTTATTCTTATGCATGCTAGAGTATTTTAAGAT
AGTAAAACTCCTTAGACTCCCATTAAAAACTATAGAGAAACGCTTCATGATAATAATCTG
TTTGAAGAGAAAGAATCTACAGTGGTTTAGAGTGCAAAGAGAAAATTTATAGAAAGGGAC
TACGATTTAGGGTAATCAGATTAATAGTAGATGATCGATGAAAACATATCTCATACAGAA
AAAAAATTCATAACTTCTGAATGCAAGTAAGAGTATGAGGGTTAGGACTCTAAGAAAAGA
CTGAAGCCTTTACTTCCTTTTAAATCCTCTATCAAGTTTTCCTGTAAAAAAAACAACTCA
TTTTCAGCATTCAATCTTTACAGAGATAAAGAAATACATACAAACATTAGTAGGTTTCCT
TAGAATTTTAAAAAATAAGATCTAGATTATGATTGCTCATCAGAAGAAGAAAGGACGGAA
GATCAAATTATATTTATGTCTGAAGAAATAATTAAAGAAATGCATAATAATTAAAGTTAT
CAATACTAAGACGCAACTAAAAGCTACTTTAATAATTGA

>TTHERM_00289290(gene)
ATGCTTATTATGGAAACTCCTCAATTTTCAGCAAAAGATAAAAATGGATAAAATTCACAA
TCTAGTTTTCATTAAGAAATTCTTCGTGCTCCAAAGAAAAATTAAACTAAAAAGACGCTT
TAAATAAAAAAAAATATTATCTTGACATCAGATGTAGCTCATGAGCTCAGAAAAATTAAT
TTTAATGATTCTCCTTTGATGAATTAGTTTATTCTTATGCATGCTAGAGTATTTTAAGAT
AGTAAAACTCCTTAGACTCCCATTAAAAACTATAGAGAAACGCTTCATGGTGATTTATCA
TTAAATAACTTGATATATTTTACTAATTTATTTATTTATTTATTTTATAGATAATAATCT
GTTTGAAGAGAAAGAATCTACAGTGGTTTAGAGTGCAAAGAGAAAATTTATAGAAAGGGG
TAAGTTTTTTTTTATTCAAGCCTCTTTTTAGTTAATTTAAATTTTTAACATTAAAGACTA
CGATTTAGGGTAATCAGATTAATAGTAGATGATCGATGAAAACATATCTCATACAGAAAA
AAAATTCATAACTTCTGAATGCAAGTAAGAGTATGAGGGTTAGGACTCTAAGAAAAGACT
GAAGCCTTTACTTCCTTTTAAATCCTCTATCAAGTTTTCCTGTAAAAAAAACAACTCATT
TTCAGCATTCAATCTTTACAGAGATAAAGAAATACATACAAACATTAGTAGGTTTCCTTA
GAATTTTAAAAAATAAGTATTGCTTTTAAATGTATTTAGATATTGCTTATTTAAATGTAT
TTAATATATTAAAAGGATCTAGATTATGATTGCTCATCAGAAGAAGAAAGGACGGAAGAT
CAAATTATATTTATGTCTGAAGAAATAATTAAAGAAATGCATAATAATTAAAGTTATCAA
TACTAAGACGCAACTAAAAGCTACTTTAATAATTGA

>TTHERM_00289290(protein)
MLIMETPQFSAKDKNGQNSQSSFHQEILRAPKKNQTKKTLQIKKNIILTSDVAHELRKIN
FNDSPLMNQFILMHARVFQDSKTPQTPIKNYRETLHDNNLFEEKESTVVQSAKRKFIERD
YDLGQSDQQQMIDENISHTEKKFITSECKQEYEGQDSKKRLKPLLPFKSSIKFSCKKNNS
FSAFNLYRDKEIHTNISRFPQNFKKQDLDYDCSSEEERTEDQIIFMSEEIIKEMHNNQSY
QYQDATKSYFNN