Identifiers and Description

Gene Model Identifier

TTHERM_00316310

Standard Name

NHX1 (Sodium Hydrogen Exchanger 1)

Aliases

PreTt20942 | 31.m00244 | 3687.m00046

Description

NHX1 sodium/hydrogen exchanger family protein; Sodium/hydrogen exchanger family protein; Cation/H+ exchanger, CPA1 family

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF00999 ) Sodium/hydrogen exchanger family

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No. Gene Name(s) Paragraph Text
2232 NHX1 NHX1 is an integral membrane protein that shares homology with other proteins containing a sodium hydrogen exchanger domain involved in transporting sodium and hydrogen ions across the concentration gradient between a cell and its surroundings. Functioning as an antiporter for sodium and hydrogen ions, the exchange function characteristic of this domain is highly dependent on pH. Although the exact molecular mechanisms responsible for this behavior are not well understood, a prominent current inference is that these exchanger proteins use ATP to transport ions across membranes. Paragraph by: Samuel Rubin and Owen Foster (undergraduates) Keck Science Deparment, Claremont Colleges

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00316310(coding)
ATGAACAATAGCACTGACACTTCAGCTGCTACATATTAGCCTAATTATTTTAGTACAATG
GCAGCATAAGCCATAGATGATTCAAAAATTAGTACAGAATCGCTTGTAGTGTTTTTCCTT
TTTGGAGGACTTATGATTGCAGGTTTTGTTAGGGAAATTAATAAAAAAACTAGCATTCCT
TACACTCCAATGCTTTTTGTTATTGGAATTTTTTTAGGAAAGTTTTCTGAAAGCATGGGA
ATACTAGGAATAACAATAAGCAAGATAAGTTTAATCAACCCTCATGGTATATTAATTATA
TTCCTCCCTGTGCTTATTTTCGAAAGTGGTTTTAATAGTGATTGGCATACTTTTAAAAAG
TAATCTGGCCAGATATTTTTACTTGCCTTCCCATGTGTACTATTTTCAGCCATATTTTTA
CTCATAAGTATCAAAGTTATTTTGAGATATGATGACTCTTATTACACTTGGAGTGGTGCA
TTTATGTTCGGTTCTATTCTCTCATGTACAGATACAGTAGCCGTCCTAGCTCTTTTAAAA
GAAGTAGGCGCTCCTAAAAAATTTAATTCGCTGATTGAAGGAGAATCATTACTTAACGAT
GGTACCTGTATGGTTCTTTTCCAAATATCAAGTGAATTCGCAAAAAAAGTTGATTAGAAT
ACATAAAATCAGTAATATTTTGATTTGTTTGAAGTGATCAAACTTTTGCTTTCTCTCACT
GTTGGTGGTACACTTCTCGGTATTGTTTTTGGCATGATAGCCTAGTTTTGGATGCGTAGA
ATACATAATGATCCGATATTGACAGTCAATATAACCTTCATTGTTTGCTATCTAACTTAC
TATGTAGCAGAAAATGTAGATATTGGAATAAAAGTCTCAGGAATTATGGCTCTAGTTTCT
CTTGGTATTTATCTCTCTATATTTGGTAAAACTAAAATTTCAAGTGAAGAAAAGAGAACT
GTTTATATTTTCTGGAAGTACGTAACTTATGCTGGTGAATCAATTATTTTTATATTAGCT
GGTGTATTAGTTGGTGTTAAAGTTTTAACATCTAATGGGGATTACGACACTATGTCAGGA
AGCGATAATGTTTCTTCTTCAATTTAAACTAGTGATTATTTTAAACTTTTTGGTCTTTAC
GTTTGTATGATCTTGAGTCGCTTTGGTAGTATTGCTTGCTTTATGTCTTGGTTGAGAAAA
TGGGGTTATGGTCTTACTTGGAAGGAAGTTTATGTCCTTGCTTACGGTGGTCTTAGAGGA
GCTATTGGTATTTCTTTTGCAATGATTGTTGCTAATGATGACTCTTACTCTCAAAAATTA
AGAGATATTATTTTATTCGATATGGCTGGAAATGCAATTTTAACATTAATTATCAATGGA
ACAACTACTGGTCCTTTGATTAAGAGTTTAGGATTATGCGTTACAAGCACAGTTAGAGAA
AGAGTCTTTTTAAATATTTTACAAGATTTGAAGGAAGATACTGAAAAAAAGATTAATTAT
TTGAAATCTAATAACTATCTAAAGATGGTCAATTGGGATAGTGTTAAAGAATATGTAGGA
TTAGCAGATTTGGAGCAAAGAATTACAAGATTAGAGTCAGATCTAACTAAAAGAGAAGAA
ATTGAAGAGTATACAAGAAATATAAGAAATAAAAATGTAATTGATGCTAAGATAGATGAA
CTTAAAAACTCTAATGAATTTTAAGAGTAGTAATCATTTGACTCAGATTCAACAAATCAC
AATCTTGATGAAAATATGATAGTTGAATGTAGAAATAGATTTTTGATGGCTCTCAAAGGA
AATTATTGGGATATTTATGAAAGAAATCAGTGCAGCAGTAATGCTTTATTATTGTTGATT
GATTCAGTAAATTGGGATCTGGATACTGAATAAGAAAGAATGAACTCATGGGAATTTCTT
TCCAATTACTTTTACAATCCTATTTACATCAAAGTGCTCTTTTAATTAAAAGGATGGCCT
ATTGTTGGATCTTATGCTGGTAACCTCCTCTTTAACCATATCTCTAATATTTATGATGTC
ATTGCTGCTTATATTGAAGCTCATGAACAAGCTGAGCAACTTTGCATAGATCAATTCCCT
TTCATTCCCTAAGTTTTAGAAATTATTATCAGAGAAAGCTAAGATAATAGAATGAGTGGC
GAAGAGTATATCAAAAATGATTTAAATGTAAGTTTCCCAGAAATTACTAAACAAATCCAA
ACTAAGAAGGCAACCTACAGTTTATTAGAGTGCTAAAAGAAAATAATAAAGAAGGGTATT
TTGTTAGGTAAGATAGATGAAAAAGAAAGAGATATATTAATGTAATAAATCGATGATAGA
GTAGTTGCTTTAGACAACATCAAACCTTCTTGGAAAGCTCCTCCAATCAAAAATTTCTTA
GAAAATGTTCCATTCTTTAAACTCATCCACAAAGATTTACTTCCATACATCATCAAAGAA
TCTGTTGAGATGATTTTTGAAAAAGATATGTACATCATCAAAGAAGGTGAGAAAGCTAAA
TACTTTTTTGTTATCACTAGAGGTAGTGCTACAGAAACAACATCTTAGAGCTTTTGCACA
TATCAAGAATAAAAGGAAGTTGGCAGTTTAATTTCTCCTCACCACTTGATTGTACCAAGT
TTGAGATACTTGACTTCCTGCATGGCTAATGCAGTTGTATACGTTCTTGCTTTCCCTTTA
AGCTCAATTTAGAAAGTTATCAAAGTTAATTTAGAAATAAAGGAATATGTTTGGATGTAG
AGTCTGAGAGCATTGAGTTAGCTTTTCTATAATGAACTTAAACCTTTAGGAAGTTTAGAT
AGAAACAGTTTTATTAAACTTCAACCAAAGTTGAAATTTGCTAAATATAACAAAGGGAAG
ACTATCTAGTGTGAAAGTGGTGGTATTCTTTTGAAAGGACAAGTTTCGAGAAAGGATTTA
ACAGATGTGATGATGACATAATCTAAAGTAAATAATGACGAGGTAAAAAAATCAGATTTG
ATTGATGGTAGAATTTATAAGGCATTTTGTGTTTTAATGCCAGGATAAGCTTTTTCAGTT
TTCACAGAAAAGAAGTGTACATTTTTGCACTTTGCTGAAGACTGTGAAGAAATTAGGTTT
ATGATTAGTCATATGGACTACAATGTTGGCATTAATTAGTAAACACCTCATACTCTTAAC
ATATTTAGTCCTGTAGCTGTTTCTGGATCTCATAATAAGAGAAACAGTTTTTAAGCTCCC
CACTTAAGTAGATTTGCAGGTAGACATACTTTTAATAATTTAGAAGTAGTTGTGCAAGGT
AGTGAAAATAAAATAAATTCAGGATAATAAATAGAATTGCAAAAGATGAAATCTAAATCA
TACTTAAACGACTAACAAATAAAGAGTGTAAAGAGTGATGATGAAGAATCAGATGATAAT
AAAGAAAAGTGA



>TTHERM_00316310(gene)
GGTATTTTTTAATATGAATTTATTTATTAGAAAAATTGAATTCTATTCAATAAAAATAAT
TATTGATTAAATTGTATCAAAAAACTAAAGCAAAGATAAGCATAATAAAATTAGTTTGAA
TAAAAAATATCTGTTTATAATTTATCAATAAATATAAGTAAGTATTAAGTAGAAAGTATG
AACAATAGCACTGACACTTCAGCTGCTACATATTAGCCTAATTATTTTAGTACAATGGCA
GCATAAGCCATAGATGATTCAAAAATTAGTACAGAATCGCTTGTAGTGTTTTTCCTTTTT
GGAGGACTTATGATTGCAGGTTTTGTTAGGGAAATTAATAAAAAAACTAGCATTCCTTAC
ACTCCAATGCTTTTTGTTATTGGAATTTTTTTAGGAAAGTTTTCTGAAAGCATGGGAATA
CTAGGAATAACAATAAGCAAGATAAGTTTAATCAACCCTCATGGTATATTAATTATATTC
CTCCCTGTGCTTATTTTCGAAAGTGGTTTTAATAGTGATTGGCATACTTTTAAAAAGTAA
TCTGGCCAGATATTTTTACTTGCCTTCCCATGTGTACTATTTTCAGCCATATTTTTACTC
ATAAGTATCAAAGTTATTTTGAGATATGATGACTCTTATTACACTTGGAGTGGTGCATTT
ATGTTCGGTTCTATTCTCTCATGTACAGATACAGTAGCCGTCCTAGCTCTTTTAAAAGAA
GTAGGCGCTCCTAAAAAATTTAATTCGCTGATTGAAGGAGAATCATTACTTAACGATGGT
ACCTGTATGGTTCTTTTCCAAATATCAAGTGAATTCGCAAAAAAAGTTGATTAGAATACA
TAAAATCAGTAATATTTTGATTTGTTTGAAGTGATCAAACTTTTGCTTTCTCTCACTGTT
GGTGGTACACTTCTCGGTATTGTTTTTGGCATGATAGCCTAGTTTTGGATGCGTAGAATA
CATAATGATCCGATATTGACAGTCAATATAACCTTCATTGTTTGCTATCTAACTTACTAT
GTAGCAGAAAATGTAGATATTGGAATAAAAGTCTCAGGAATTATGGCTCTAGTTTCTCTT
GGTATTTATCTCTCTATATTTGGTAAAACTAAAATTTCAAGTGAAGAAAAGAGAACTGTT
TATATTTTCTGGAAGTACGTAACTTATGCTGGTGAATCAATTATTTTTATATTAGCTGGT
GTATTAGTTGGTGTTAAAGTTTTAACATCTAATGGGGATTACGACACTATGTCAGGAAGC
GATAATGTTTCTTCTTCAATTTAAACTAGTGATTATTTTAAACTTTTTGGTCTTTACGTT
TGTATGATCTTGAGTCGCTTTGGTAGTATTGCTTGCTTTATGTCTTGGTTGAGAAAATGG
GGTTATGGTCTTACTTGGAAGGAAGTTTATGTCCTTGCTTACGGTGGTCTTAGAGGAGCT
ATTGGTATTTCTTTTGCAATGATTGTTGCTAATGATGACTCTTACTCTCAAAAATTAAGA
GATATTATTTTATTCGATATGGCTGGAAATGCAATTTTAACATTAATTATCAATGGAACA
ACTACTGGTCCTTTGATTAAGAGTTTAGGATTATGCGTTACAAGCACAGTTAGAGAAAGA
GTCTTTTTAAATATTTTACAAGATTTGAAGGAAGATACTGAAAAAAAGATTAATTATTTG
AAATCTAATAACTATCTAAAGATGGTCAATTGGGATAGTGTTAAAGAATATGTAGGATTA
GCAGATTTGGAGCAAAGAATTACAAGATTAGAGTCAGATCTAACTAAAAGAGAAGAAATT
GAAGAGTATACAAGAAATATAAGAAATAAAAATGTAATTGATGCTAAGATAGATGAACTT
AAAAACTCTAATGAATTTTAAGAGTAGTAATCATTTGACTCAGATTCAACAAATCACAAT
CTTGATGAAAATATGATAGTTGAATGTAGAAATAGATTTTTGATGGCTCTCAAAGGAAAT
TATTGGGATATTTATGAAAGAAATCAGTGCAGCAGTAATGCTTTATTATTGTTGATTGAT
TCAGTAAATTGGGATCTGGATACTGAATAAGAAAGAATGAACTCATGGGAATTTCTTTCC
AATTACTTTTACAATCCTATTTACATCAAAGTGCTCTTTTAATTAAAAGGATGGCCTATT
GTTGGATCTTATGCTGGTAACCTCCTCTTTAACCATATCTCTAATATTTATGATGTCATT
GCTGCTTATATTGAAGCTCATGAACAAGCTGAGCAACTTTGCATAGATCAATTCCCTTTC
ATTCCCTAAGTTTTAGAAATTATTATCAGAGAAAGCTAAGATAATAGAATGAGTGGCGAA
GAGTATATCAAAAATGATTTAAATGTAAGTTTCCCAGAAATTACTAAACAAATCCAAACT
AAGAAGGCAACCTACAGTTTATTAGAGTGCTAAAAGAAAATAATAAAGAAGGGTATTTTG
TTAGGTAAGATAGATGAAAAAGAAAGAGATATATTAATGTAATAAATCGATGATAGAGTA
GTTGCTTTAGACAACATCAAACCTTCTTGGAAAGCTCCTCCAATCAAAAATTTCTTAGAA
AATGTTCCATTCTTTAAACTCATCCACAAAGATTTACTTCCATACATCATCAAAGAATCT
GTTGAGATGATTTTTGAAAAAGATATGTACATCATCAAAGAAGGTGAGAAAGCTAAATAC
TTTTTTGTTATCACTAGAGGTAGTGCTACAGAAACAACATCTTAGAGCTTTTGCACATAT
CAAGAATAAAAGGAAGTTGGCAGTTTAATTTCTCCTCACCACTTGATTGTACCAAGTTTG
AGATACTTGACTTCCTGCATGGCTAATGCAGTTGTATACGTTCTTGCTTTCCCTTTAAGC
TCAATTTAGAAAGTTATCAAAGTTAATTTAGAAATAAAGGAATATGTTTGGATGTAGAGT
CTGAGAGCATTGAGTTAGCTTTTCTATAATGAACTTAAACCTTTAGGAAGTTTAGATAGA
AACAGTTTTATTAAACTTCAACCAAAGTTGAAATTTGCTAAATATAACAAAGGGAAGACT
ATCTAGTGTGAAAGTGGTGGTATTCTTTTGAAAGGACAAGTTTCGAGAAAGGATTTAACA
GATGTGATGATGACATAATCTAAAGTAAATAATGACGAGGTAAAAAAATCAGATTTGATT
GATGGTAGAATTTATAAGGCATTTTGTGTTTTAATGCCAGGATAAGCTTTTTCAGTTTTC
ACAGAAAAGAAGTGTACATTTTTGCACTTTGCTGAAGACTGTGAAGAAATTAGGTTTATG
ATTAGTCATATGGACTACAATGTTGGCATTAATTAGTAAACACCTCATACTCTTAACATA
TTTAGTCCTGTAGCTGTTTCTGGATCTCATAATAAGAGAAACAGTTTTTAAGCTCCCCAC
TTAAGTAGATTTGCAGGTAGACATACTTTTAATAATTTAGAAGTAGTTGTGCAAGGTAGT
GAAAATAAAATAAATTCAGGATAATAAATAGAATTGCAAAAGATGAAATCTAAATCATAC
TTAAACGACTAACAAATAAAGAGTGTAAAGAGTGATGATGAAGAATCAGATGATAATAAA
GAAAAGTGAAGAAAAAGACAACAACAAAAAAATTTAGTTTAAAAGATAATTTAAAGATTG
ATTTATTCAAATATTTTATTTAAATATATATATATTTTAAATAATATTATATTACATAAA
TAAATAAATATCGAAAAGGATTTGTATATATGTGAAGGTGACTAAAATATTAAAGTTTTT
TAAATATTCACAAAACAATTACTTTGAAAAAA



>TTHERM_00316310(protein)
MNNSTDTSAATYQPNYFSTMAAQAIDDSKISTESLVVFFLFGGLMIAGFVREINKKTSIP
YTPMLFVIGIFLGKFSESMGILGITISKISLINPHGILIIFLPVLIFESGFNSDWHTFKK
QSGQIFLLAFPCVLFSAIFLLISIKVILRYDDSYYTWSGAFMFGSILSCTDTVAVLALLK
EVGAPKKFNSLIEGESLLNDGTCMVLFQISSEFAKKVDQNTQNQQYFDLFEVIKLLLSLT
VGGTLLGIVFGMIAQFWMRRIHNDPILTVNITFIVCYLTYYVAENVDIGIKVSGIMALVS
LGIYLSIFGKTKISSEEKRTVYIFWKYVTYAGESIIFILAGVLVGVKVLTSNGDYDTMSG
SDNVSSSIQTSDYFKLFGLYVCMILSRFGSIACFMSWLRKWGYGLTWKEVYVLAYGGLRG
AIGISFAMIVANDDSYSQKLRDIILFDMAGNAILTLIINGTTTGPLIKSLGLCVTSTVRE
RVFLNILQDLKEDTEKKINYLKSNNYLKMVNWDSVKEYVGLADLEQRITRLESDLTKREE
IEEYTRNIRNKNVIDAKIDELKNSNEFQEQQSFDSDSTNHNLDENMIVECRNRFLMALKG
NYWDIYERNQCSSNALLLLIDSVNWDLDTEQERMNSWEFLSNYFYNPIYIKVLFQLKGWP
IVGSYAGNLLFNHISNIYDVIAAYIEAHEQAEQLCIDQFPFIPQVLEIIIRESQDNRMSG
EEYIKNDLNVSFPEITKQIQTKKATYSLLECQKKIIKKGILLGKIDEKERDILMQQIDDR
VVALDNIKPSWKAPPIKNFLENVPFFKLIHKDLLPYIIKESVEMIFEKDMYIIKEGEKAK
YFFVITRGSATETTSQSFCTYQEQKEVGSLISPHHLIVPSLRYLTSCMANAVVYVLAFPL
SSIQKVIKVNLEIKEYVWMQSLRALSQLFYNELKPLGSLDRNSFIKLQPKLKFAKYNKGK
TIQCESGGILLKGQVSRKDLTDVMMTQSKVNNDEVKKSDLIDGRIYKAFCVLMPGQAFSV
FTEKKCTFLHFAEDCEEIRFMISHMDYNVGINQQTPHTLNIFSPVAVSGSHNKRNSFQAP
HLSRFAGRHTFNNLEVVVQGSENKINSGQQIELQKMKSKSYLNDQQIKSVKSDDEESDDN
KEK