Identifiers and Description

Gene Model Identifier

TTHERM_00486480

Standard Name

ENO1 (ENOlase 1)

Aliases

PreTt19579 | 59.m00217 | 3680.m00074

Description

ENO1 carboxy-terminal TIM barrel domain enolase; Enolase; portions of this gene may have been laterally transferred

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Cellular Component

• plasmodesmatal plasma membrane (IEA) | GO:0009548

Molecular Function

• lactase activity (IEA) | GO:0000016
• RNA trimethylguanosine cap binding (IEA) | GO:0000341

Biological Process

• adult heart development (IEA) | GO:0007512
• amine biosynthetic process (IDA) | GO:0009309 | Ref:17785518
• axon guidance (ISS) | GO:0007411 | Ref:11526220
• oligosaccharide biosynthetic process (IDA) | GO:0009312 | Ref:17785518

Domains

• ( PF00113 ) Enolase, C-terminal TIM barrel domain
• ( PF01188 ) Mandelate racemase / muconate lactonizing
• ( PF03952 ) Enolase, N-terminal domain
• ( TIGR01060 ) phosphopyruvate hydratase

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_4496	0
	Description: None
Tetrahymena borealis	EI9_12148.1	9.997093137033517e-262
	Description: enolase (441 aa)
DictyBase	DDB_G0283137	9.997093137033517e-262
	Description: enoA on chromosome: 4 position 225309 to 226956
Oxytricha	Contig15891.0.g72	9.997093137033517e-262
	Description: Enolase, C-terminal TIM barrel domain
WormBase	WBGene00011884	1.9999987447608204e-178
	Description: locus:enol-1 Enolase status:Confirmed UniProt:Q27527 protein_id:CAA92692.1
SGD	YGR254W	2.0002969069156684e-168
	Description: ENO1 Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose

General Information

No Data fetched for General Information

Associated Literature

1. Ref:17785518: Kilburn CL, Pearson CG, Romijn EP, Meehl JB, Giddings TH, Culver BP, Yates JR, Winey M (2007) New Tetrahymena basal body protein components identify basal body domain structure. The Journal of cell biology 178(6):905-12
2. Ref:11526220: Keeling PJ and Palmer JD (2001) Lateral transfer at the gene and subgenic levels in the evolution of eukaryotic enolase. Proc Natl Acad Sci U S A 98(19):10745-50

Sequences

>TTHERM_00486480(coding)
ATGGCTACTATTAAAGATATCAAAGCTAGAGAAATACTAGATTCTAGAGGTAATCCTACT
GTTGAAGTTGATTTGACAGTAGATAATGGTCAAGTTTTTAGAGCTGCTGTTCCTTCTGGT
GCTTCAACAGGTATCTATGAAGCCTGTGAACTTAGAGACGGGGATAATCACAGATATTTA
GGGAAAGGTGTTTTGAAGGCTGTAAACAATGTGAACACCATCATTAAACCTCATTTAATT
GGTAAAAATGTTACTGAATAAGAATAATTAGATAAGTTAATGGTAGAATAGCTTGATGGA
ACTAAAAATGAATGGGGTTGGTGCAAAAGCAAATTAGGAGCAAATGCTATTTTAGCAGTT
TCTATGGCTGTTGCCAGAGCTGCCGCAGCTCATAAGAACCTTCCTTTATACAAATACTTG
TCTCATTTGAATGGATAAGACAACCTAACCCAATTCAATTTACCTCTTCCATTCTTCAAT
GTCATTAATGGTGGAAAGCATGCAGGAAACAAATTAGCTTTCTAAGAGTTTATGTTCACA
CCATGCGGTGCATCTAACTTTGCAGAAGGTCTAAGAATGGGTGCTGAGGTTTATCACAAC
TTAAAGAAAGTAATTGAAAAAAAGTACGGACAAACAGCTACTAATGTAGGTGATGAAGGA
GGTTTTGCCCCAGATACTAGTAATCCAGATGAAGCATTAGAATTACTAGTTGAAGCTATC
AAGAAGGCAGGTCATGAAGGAAAGATTAAAATATCTATGGATGTTGCAGCTTCTGAATTC
TACGACGCTAAAACTAAGCTTTATGATTTAGATTTTAAGAATAGTAACTCAGATGGTAAG
CATAAGTTAACTTCTGAATAGTTAGTTGAATACTTTGCCAATTTAGTTTCAAAATATCCA
ATTTTTTCAATTGAAGATCCTTTCGACTAGGATGACTGGGCTGCTTATGCTCAATTGACT
GCTCGTATTGGTAATTAAGTCAAGATTGTTGGTGATGACTTACTTGTTACTAACCCTTTA
CGTGCAGAAAAAGCTATTTAAGAAAAAGCCTGTAATTATCTTCTACTTAAAGTCAATCAA
ATTGGAACAGTAACAGAAGCAATTTAAACATATCAAATTGTCTCTAAAGCCAACTTTGGA
ACTATGGTCTCACATAGATCAGGTGAAACTGAAGATACTTTCATAGCTGATTTAGTTGTA
GGAATAGGTGCTGCTACAATTAAAACTGGTGCTCCCTGCAGATCTGAAAGATTAGCTAAA
TATAATTAGCTTATCAGAATTGAAGAAGAGCTTGGTCAAAATTCTACTTATGGAAAAAAT
CACTGA

>TTHERM_00486480(gene)
ATGGCTACTATTAAAGATATCAAAGCTAGAGAAATACTAGATTCTAGAGGTAATCCTACT
GTTGAAGTTGATTTGACAGTAGATAATGGTCAAGTTTTTAGAGCTGCTGTTCCTTCTGGT
GCTTCAACAGGTATCTATGAAGCCTGTGAACTTAGAGACGGGGATAATCACAGATATTTA
GGGAAAGGTGTTTTGAAGGCTGTAAACAATGTGAACACCATCATTAAACCTCATTTAATT
GGTAAAAATGTTACTGAATAAGAATAATTAGATAAGTTAATGGTAGAATAGCTTGATGGA
ACTAAAAATGAATGGGGTTGGTGCAAAAGCAAATTAGGAGCAAATGCTATTTTAGCAGTT
TCTATGGCTGTTGCCAGAGCTGCCGCAGCTCATAAGAACCTTCCTTTATACAAGTAAATA
TTTTTAAAATTCTATTTCAAATTATAAAAAGCCTCTTTACTTTATTTAAAAACCAAATCT
TATCATCTTTGCATTAACATTTTTTATGGAAGATTTTAAAACTTTGCAGCAATAAATACT
TAGGTTAAAAGCTTCATATAAACAAAAAAACATGAAATTATTTATTCCTAACTTAATATA
AATAAAATTAAACTAGATACTTGTCTCATTTGAATGGATAAGACAACCTAACCCAATTCA
ATTTACCTCTTCCATTCTTCAATGTCATTAATGGTGGAAAGCATGCAGGAAACAAATTAG
CTTTCTAAGAGTTTATGTTCACACCATGCGGTGCATCTAACTTTGCAGAAGGTCTAAGAA
TGGGTGCTGAGGTTTATCACAACTTAAAGAAAGTAATTGAAAAAAAGTACGGACAAACAG
CTACTAATGTAGGTGATGAAGGAGGTTTTGCCCCAGATACTAGTAATCCAGATGAAGCAT
TAGAATTACTAGTTGAAGCTATCAAGAAGGCAGGTCATGAAGGAAAGATTAAAATATCTA
TGGATGTTGCAGCTTCTGAATTCTACGACGCTAAAACTAAGCTTTATGATTTAGATTTTA
AGAATAGTAACTCAGATGGTAAGCATAAGTTAACTTCTGAATAGTTAGTTGAATACTTTG
CCAATTTAGTTTCAAAATATCCAATTTTTTCAATTGAAGATCCTTTCGACTAGGATGACT
GGGCTGCTTATGCTCAATTGACTGCTCGTATTGGTAATTAAGTCAAGATTGTTGGTGATG
ACTTACTTGTTACTAACCCTTTACGTGCAGAAAAAGCTATTTAAGAAAAAGCCTGTAATT
ATCTTCTACTTAAAGTCAATCAAATTGGAACAGTAACAGAAGCAATTTAAACATATCAAA
TTGTCTCTAAAGCCAACTTTGGAACTATGGTCTCACATAGATCAGGTGAAACTGAAGATA
CTTTCATAGCTGATTTAGTTGTAGGAATAGGTGCTGCTACAATTAAAACTGGTGCTCCCT
GCAGATCTGAAAGATTAGCTAAATATAATTAGCTTATCAGAATTGAAGAAGAGCTTGGTC
AAAATTCTACTTATGGAAAAAATCACTGA

>TTHERM_00486480(protein)
MATIKDIKAREILDSRGNPTVEVDLTVDNGQVFRAAVPSGASTGIYEACELRDGDNHRYL
GKGVLKAVNNVNTIIKPHLIGKNVTEQEQLDKLMVEQLDGTKNEWGWCKSKLGANAILAV
SMAVARAAAAHKNLPLYKYLSHLNGQDNLTQFNLPLPFFNVINGGKHAGNKLAFQEFMFT
PCGASNFAEGLRMGAEVYHNLKKVIEKKYGQTATNVGDEGGFAPDTSNPDEALELLVEAI
KKAGHEGKIKISMDVAASEFYDAKTKLYDLDFKNSNSDGKHKLTSEQLVEYFANLVSKYP
IFSIEDPFDQDDWAAYAQLTARIGNQVKIVGDDLLVTNPLRAEKAIQEKACNYLLLKVNQ
IGTVTEAIQTYQIVSKANFGTMVSHRSGETEDTFIADLVVGIGAATIKTGAPCRSERLAK
YNQLIRIEEELGQNSTYGKNH