Identifiers and Description

Gene Model Identifier

TTHERM_00564190

Standard Name

Aliases

PreTt08957 | 75.m00155 | 3721.m00037 | TPPT1

Description

Protein-Tyrosine Phosphatase

Genome Browser (Macronucleus)



Genome Browser (Micronucleus)

External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

  • (R)-mevalonic acid biosynthetic process (IEA) | GO:1901737
  • absorption of visible light (IEA) | GO:0016038
  • anaerobic respiration (IEA) | GO:0009061
  • anterior mesonephric tubule development (IEA) | GO:0072165
  • cardiac muscle cell contraction (IEA) | GO:0086003
  • cell wall modification involved in fruit ripening (IEA) | GO:0009829
  • ceramide phosphoethanolamine catabolic process (IEA) | GO:1905372
  • cytoplasmic actin-based contraction involved in forward cell motility (IEA) | GO:0060328
  • cytosine transport (IEA) | GO:0015856
  • detection of auxin stimulus (IEA) | GO:0009721
  • fibroblast growth factor receptor signaling pathway (IEA) | GO:0008543
  • fucose metabolic process (IEA) | GO:0006004
  • galactose to glucose-1-phosphate metabolic process (IEA) | GO:0061612
  • glomerular mesangial cell development (IEA) | GO:0072144
  • glycolytic process from glycerol (IEA) | GO:0061613
  • hair cycle process (IEA) | GO:0022405
  • heme A biosynthetic process (IEA) | GO:0006784
  • heme biosynthetic process (IEA) | GO:0006783
  • L-alanine catabolic process (IEA) | GO:0042853
  • macromolecule biosynthetic process (IEA) | GO:0009059
  • mesenchymal cell proliferation involved in ureteric bud development (IEA) | GO:0072138
  • mitotic nuclear division (IEA) | GO:0007067
  • monoterpenoid catabolic process (IEA) | GO:0016100
  • mRNA splicing, via endonucleolytic cleavage and ligation (IEA) | GO:0070054
  • negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
  • negative regulation of double-strand break repair via nonhomologous end joining (IEA) | GO:2001033
  • negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
  • negative regulation of immune effector process (IEA) | GO:0002698
  • negative regulation of interleukin-10 secretion (IEA) | GO:2001180
  • negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
  • negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
  • negative regulation of phytoalexin metabolic process (IEA) | GO:0052321
  • negative regulation of postsynaptic membrane organization (IEA) | GO:1901627
  • negative regulation of vasculogenesis (IEA) | GO:2001213
  • obsolete histone succinylation (IEA) | GO:0106077
  • obsolete negative regulation of transcription during mitotic cell cycle (IEA) | GO:0007068
  • obsolete positive regulation by host of symbiont defense response (IEA) | GO:0052197
  • obsolete positive regulation by organism of defense-related symbiont reactive oxygen species production (IEA) | GO:0052349
  • obsolete positive regulation of adhesion of symbiont to host epithelial cell (IEA) | GO:1905228
  • obsolete positive regulation of G2 phase of mitotic cell cycle (IEA) | GO:2001221
  • ommochrome biosynthetic process (IEA) | GO:0006727
  • oxidative phosphorylation (IEA) | GO:0006119
  • parathion metabolic process (IEA) | GO:0018952
  • phagocytosis (IEA) | GO:0006909
  • plant-type cell wall modification (IEA) | GO:0009827
  • positive regulation of ATF6-mediated unfolded protein response (IEA) | GO:1903893
  • positive regulation of forebrain neuron differentiation (IEA) | GO:2000979
  • positive regulation of interleukin-10 secretion (IEA) | GO:2001181
  • positive regulation of ovulation (IEA) | GO:0060279
  • positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
  • positive regulation of protein acetylation (IEA) | GO:1901985
  • positive regulation of response to water deprivation (IEA) | GO:1902584
  • positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
  • priming of cellular response to stress (IEA) | GO:0080136
  • protein localization to old growing cell tip (IEA) | GO:1903858
  • protein transport into membrane raft (IEA) | GO:0032596
  • purine ribonucleoside triphosphate metabolic process (IEA) | GO:0009205
  • regulation of capsule polysaccharide biosynthetic process (IEA) | GO:0062084
  • regulation of cellular glucuronidation (IEA) | GO:2001029
  • regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
  • regulation of dendrite extension (IEA) | GO:1903859
  • regulation of L-arginine import into cell (IEA) | GO:1902826
  • regulation of phosphatidylcholine biosynthetic process (IEA) | GO:2001245
  • regulation of Rac protein signal transduction (IEA) | GO:0035020
  • regulation of response to type II interferon (IEA) | GO:0060330
  • regulation of transcriptional start site selection at RNA polymerase II promoter (IEA) | GO:0001178
  • sensory organ boundary specification (IEA) | GO:0008052
  • signal transduction involved in G1/S transition checkpoint (IEA) | GO:0072404
  • transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript (IEA) | GO:0001180

Domains

  • ( PF00102 ) Protein-tyrosine phosphatase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No. Gene Name(s) Paragraph Text
2325 (no standard gene name) Tetrahymena thermophilia’s TPPT1 protein is homologous with proteins in the Y phosphatase family associated with the removal of phosphate groups from tyrosine residues. It contains 1 domain (E-value= 2.9E-67), which is a Y phosphatase domain. The closest homologs are found in Paramecium tetraurelia, Ichthyopthirius multifiliis, a freshwater fish disease, and Stentor coeruleus, a large ciliate. It is possible that this protein is involved in cell signaling pathways. Paragraph by: Margot Chisholm, Keck Science Center, Pitzer College.

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00564190(coding)
ATGGACACAAAAAATAATTTGTAATAGGAAGAAGCCTTTTATGAAAAATTTGCAGTACCT
CCAGCTCCAATTAAAAAAGAAGAAATTGATTATTCATATACAGAAGAGTTAAAAGCAGAG
ACAAGAAAAATTAAGGATTTGCTGAATTTCAAAATGACTAATTAGTTTTAAGTATTGTAA
ATGATCACTCATACAAATAATCATCATAATAATAGAATCAAAGCAAATGAATTTTTAGAT
TATAATAGATATACTGATATTCTACCATATAAGCATTCAGTTGTTAAAATTAGCGGAAGT
ACCTAAGTTGATTAATACATAAATGCTAATTACATAAATAATCCCTTTAAAGATAAAGCT
TATATTGCTACTCAAGGACCTATTCCAAATACAATCTCTTCTTTTTGGAGAATGATATGG
GAATAAAAAACAAATTTGATTATTATGCTTTGCAAGGAATTCGTTAAATGTGATAAATAT
TGGCCAAGCCAAGGATAGATCTTATAGGAGGGAGATTTGCAAGTCCAATTTTTATCGTAG
TAAAAAAATGCATAATAGAATATTATTGAAAGACAATTCATACTCAAGTATAAAAATGAA
TAACGTTAAGTCTCTTAAGTGCATTGGGAAGGATGGCCAGATCATGGTGTTCCTGAAAGT
AGAGATTATGGAGTTTTAGAAAATTTAGTATAAAGGGTAGTAAATCAAATTGAATAGTCC
AAGATTCCTGTCGTGCATTGCAGTGCTGGAGTTGGTAGAACTGGTACATTGTTAGCCCTC
TCTAATATTTACATGACTTTGAAATATCATTAAGTTAAAAAAACTCCTATAGACTAAATA
GAATTAAACGTCTTAGATATAGTTAGAAGACTTAGAGAGTAAAGAATGATCATGGTATAA
ATGGATAACTAATTAAACTTAGTATATGAAATTACAAAAACTTTTATCAGAAAAATGTTC
AAATTTTGA


>TTHERM_00564190(gene)
CAATAAATAATTAAATTTATAAGATATAAAAAATCAAAAGATAACAAGATCATCAAGAAG
CTCTAAGTGAAGTAAAAATAGAAATGGACACAAAAAATAATTTGTAATAGGAAGAAGCCT
TTTATGAAAAATTTGCAGTACCTCCAGCTCCAATTAAAAAAGAAGAAATTGATTATTCAT
ATACAGAAGAGTTAAAAGCAGAGACAAGAAAAATTAAGGATTTGCTGAATTTCAAAATGA
CTAATTAGTTTTAAGTATTGTAAATGATCACTCATACAAATAATCATCATAATAATAGAA
TCAAAGCAAATGAATTTTTAGATTATAATAGATATACTGATATTCTACCATATAAGCATT
CAGTTGTTAAAATTAGCGGAAGTACCTAAGTTGATTAATACATAAATGCTAATTACATAA
ATAATCCCTTTAAAGATAAAGCTTATATTGCTACTCAAGGACCTATTCCAAATACAATCT
CTTCTTTTTGGAGAATGATATGGGAATAAAAAACAAATTTGATTATTATGCTTTGCAAGG
AATTCGTTAAATGTGATAAATATTGGCCAAGCCAAGGATAGATCTTATAGGAGGGAGATT
TGCAAGTCCAATTTTTATCGTAGTAAAAAAATGCATAATAGAATATTATTGAAAGACAAT
TCATACTCAAGTATAAAAATGAATAACGTTAAGTCTCTTAAGTGCATTGGGAAGGATGGC
CAGATCATGGTGTTCCTGAAAGTAGAGATTATGGAGTTTTAGAAAATTTAGTATAAAGGG
TAGTAAATCAAATTGAATAGTCCAAGATTCCTGTCGTGCATTGCAGTGCTGGAGTTGGTA
GAACTGGTACATTGTTAGCCCTCTCTAATATTTACATGACTTTGAAATATCATTAAGTTA
AAAAAACTCCTATAGACTAAATAGAATTAAACGTCTTAGATATAGTTAGAAGACTTAGAG
AGTAAAGAATGATCATGGTATAAATGGATAACTAATTAAACTTAGTATATGAAATTACAA
AAACTTTTATCAGAAAAATGTTCAAATTTTGAGAATCAAAAATAAATAACTTACCTTTGT
TAAATAATCTAAATTTTTGAATTTAATTAAAATATTTAAATTTGACTTTTTCAATAGTTC
TTGAGTTAAAATATATGTAGTTATTTAATAAGTTAATTACTTAGCTATTTAGTCATTTAT
TTATTTTACTTATTAACTTACTTACTGATTTAGTAGTAGAATGTACTTTTAAATTATAAT
TTAATATTTTGGGATATATTATC


>TTHERM_00564190(protein)
MDTKNNLQQEEAFYEKFAVPPAPIKKEEIDYSYTEELKAETRKIKDLLNFKMTNQFQVLQ
MITHTNNHHNNRIKANEFLDYNRYTDILPYKHSVVKISGSTQVDQYINANYINNPFKDKA
YIATQGPIPNTISSFWRMIWEQKTNLIIMLCKEFVKCDKYWPSQGQILQEGDLQVQFLSQ
QKNAQQNIIERQFILKYKNEQRQVSQVHWEGWPDHGVPESRDYGVLENLVQRVVNQIEQS
KIPVVHCSAGVGRTGTLLALSNIYMTLKYHQVKKTPIDQIELNVLDIVRRLREQRMIMVQ
MDNQLNLVYEITKTFIRKMFKF