Identifiers and Description

Gene Model Identifier

TTHERM_00691720

Standard Name

ICT1 (Integral-membrane Cation Transporter 1)

Aliases

PreTt03010 | 106.m00150 | 3674.m00063

Description

ICT1 NRAMP (natural resistance-associated macrophage protein) metal ion transporter family protein; NRAMP family Mn2+/Fe2+ transporters containing protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

Molecular Function

Biological Process

Domains

  • ( PF01461 ) 7TM chemoreceptor
  • ( PF01566 ) Natural resistance-associated macrophage protein
  • ( PF07690 ) transporter, major facilitator family
  • ( PF07695 ) 7TM diverse intracellular signalling
  • ( TIGR01197 ) metal ion transporter, metal ion

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_17571.1 9.997093137033517e-262
Description: NRAMP family Mn2+/Fe2+ transporters containing protein (488 aa)
Oxytricha Contig20600.0.g69 3.999836123447869e-144
Description: Natural resistance-associated macrophage protein
DictyBase DDB_G0276973 2.0007666164339447e-112
Description: nramp1 on chromosome: 2 position 7564058 to 7565770
WormBase WBGene00004876 6.000988504514371e-99
Description: locus:smf-1 NRAMP-like transporter smf-1 status:Confirmed UniProt:Q21434 protein_id:CCD70800.1
SGD YOL122C 9.002663577881587e-59
Description: SMF1 Divalent metal ion transporter with a broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins

General Information

No. Gene Name(s) Paragraph Text
43 ICT1 Tetrahymena thermophila ICT1 is homologous to the natural resistance-associated macrophage protein (NRAMP) family, composed of membrane proteins that are divalent cation transporters. It contains one domain (E-value=3.7x10-108), which is located in the middle of the protein. Given the function of the homologous proteins, it is likely that ICT1 is an integral membrane protein and functions as a cation transporter. Paragraph by: Alec Koh and Katherine Tully (undergraduates), Keck Science Department, Claremont McKenna College and Scripps College.

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00691720(coding)
ATGGCTGAAGTAGGATAGAACAATATCAATTCTGGAACTGTTAACAGCAATGATCATTAA
GAGAAAATTAATGTAAAGTTTTCATTAAGGGAATTTTTCTAATATTTTGGACCAGGCTTA
CTCGTAGCTATCGCTTACATCGATCCTGGTAATTTGGCTGGTGATATGGATGCAGGTTTA
AATGGTAAATATCACTTGTTATGGGTACTTTTCTTATCAACACTCTTAGGTTTCTTCTTT
TAAAACCGTGCTATGATGATTGGTTTGGTTACTGGAAAAGATATGGCTAAATTATGTCGC
TACTATTATCCTAAAAAAATGTCTATCTTGTTATGGATTATGGCTGAAATCGCTATTATA
GGCAGTGATATTCAAGAAGTATTAGGATCTGCTATTGCATTATAAATTCTTTTTGGACTC
AAATTATGGATCGGAGTTATCTTAACTATTTCTTCTACTATTCTTATTTTATTAATAAAA
TATGTTGGTATGCGCTTTTTAGAATTAATCTTTGGTATTCTTATAGGAACTATGGCTATT
TGCTTCTTTATTGATCTTGGTTACATTGCTCCTAATTTCGGTGAATTAATGGAAGGAATG
TTTGTCCCTTACATCCCATCATCTGCACTCACTTCCATGGTTGGTTTAATAGGTGCTGTC
CTCATGCCTCACAATCTATATCTTCATTCATCTCTTGTTTATGAAAAGAAGATTTCCAGA
AATGACAGACCTCTTCTCCATAAATCCATTTTTTATTTCAAAATTGAAACAGGTATCTCT
CTCCTAATTTCTTTCTTCATAAACATGGCAGTCATTGGTACTTTTGCTAATTGGTACAAT
AGTGGAACAGATATTGATTTAAGCTCTGCTGCCACAGTCCTTGAAGAAAACTTTGGTGCA
GCTGCCAAGTACATTTGGGGTATCGGTTTATTGGCTGCTGGTTAATCATCAACTTTAACT
GGTACTCTTGCTGGTTAATTTGTCATGTCTGGATTTGTTAAAATGAGAGTAAGCAAGTTC
AAAAGAGCTTTTATTACTCGTGCTATTGCAATCGTTCCTGCTATTGTTATAGCTTTTATT
GCTGATGATGAAGACTTTAATAACTATTTAAATATTCTTCAAGCAATACAACTTCCCTTT
GCCGTTATTCCACTTCTTAAGCTTTCAATGGATAGAGAACTCATGGGTGAATTTACTATT
GGTAAAGTTCAATTAACTTTATTGAGTGTCCTTTCCGCTGCTATTGTAGGAGTAAACTAT
TACGCATCAGTACCTGATGAAGTAAACTGGTCTGAAGCTTGGATCTATATCATTCTCGTA
GTTATGGTTTTATACTTTATCTTTTTAGGAATCGTGCTTTTCACTAAAATTAAAGATACT
AAGGACGTCAAATAAAGTATGCTATCAAATCATAAGCAATCTTTAATTTAAGATGATGAA
TAATATCATGTTAAATAATGA


>TTHERM_00691720(gene)
ATGGCTGAAGTAGGATAGAACAATATCAATTCTGGAACTGTTAACAGCAATGATCATTAA
GAGAAAATTAATGTAAAGTTTTCATTAAGGGAATTTTTCTAATATTTTGGACCAGGCTTA
CTCGTAGCTATCGCTTACATCGATCCTGGTAATTTGGCTGGTGATATGGATGCAGGTTTA
AATGGTAAATATCACTTGTTATGGGTACTTTTCTTATCAACACTCTTAGGTTTCTTCTTT
TAAAACCGTGCTATGATGATTGGTTTGGTTACTGGAAAAGATATGGCTAAATTATGTCGC
TACTATTATCCTAAAAAAATGTCTATCTTGTTATGGATTATGGCTGAAATCGCTATTATA
GGCAGTGATATTCAAGAAGTATTAGGATCTGCTATTGCATTATAAATTCTTTTTGGACTC
AAATTATGGATCGGAGTTATCTTAACTATTTCTTCTACTATTCTTATTTTATTAATAAAA
TATGTTGGTATGCGCTTTTTAGAATTAATCTTTGGTATTCTTATAGGAACTATGGCTATT
TGCTTCTTTATTGATCTTGGTTACATTGCTCCTAATTTCGGTGAATTAATGGAAGGAATG
TTTGTCCCTTACATCCCATCATCTGCACTCACTTCCATGGTTGGTTTAATAGGTGCTGTC
CTCATGCCTCACAATCTATATCTTCATTCATCTCTTGTTTATGAAAAGAAGATTTCCAGA
AATGACAGACCTCTTCTCCATAAATCCATTTTTTATTTCAAAATTGAAACAGGTATCTCT
CTCCTAATTTCTTTCTTCATAAACATGGCAGTCATTGGTACTTTTGCTAATTGGTACAAT
AGTGGAACAGATATTGATTTAAGCTCTGCTGCCACAGTCCTTGAAGAAAACTTTGGTGCA
GCTGCCAAGTACATTTGGGGTATCGGTTTATTGGCTGCTGGTTAATCATCAACTTTAACT
GGTACTCTTGCTGGTTAATTTGTCATGTCTGGATTTGTTAAAATGAGAGTAAGCAAGTTC
AAAAGAGCTTTTATTACTCGTGCTATTGCAATCGTTCCTGCTATTGTTATAGCTTTTATT
GCTGATGATGAAGACTTTAATAACTATTTAAATATTCTTCAAGCAATACAACTTCCCTTT
GCCGTTATTCCACTTCTTAAGCTTTCAATGGATAGAGAACTCATGGGTGAATTTACTATT
GGTAAAGTTCAATTAACTTTATTGAGTGTCCTTTCCGCTGCTATTGTAGGAGTAAACTAT
TACGCATCAGTACCTGATGAAGTAAACTGGTCTGAAGCTTGGATCTATATCATTCTCGTA
GTTATGGTTTTATACTTTATCTTTTTAGGAATCGTGCTTTTCACTAAAATTAAAGATACT
AAGGACGTCAAATAAAGTATGCTATCAAATCATAAGCAATCTTTAATTTAAGATGATGAA
TAATATCATGTTAAATAATGA


>TTHERM_00691720(protein)
MAEVGQNNINSGTVNSNDHQEKINVKFSLREFFQYFGPGLLVAIAYIDPGNLAGDMDAGL
NGKYHLLWVLFLSTLLGFFFQNRAMMIGLVTGKDMAKLCRYYYPKKMSILLWIMAEIAII
GSDIQEVLGSAIALQILFGLKLWIGVILTISSTILILLIKYVGMRFLELIFGILIGTMAI
CFFIDLGYIAPNFGELMEGMFVPYIPSSALTSMVGLIGAVLMPHNLYLHSSLVYEKKISR
NDRPLLHKSIFYFKIETGISLLISFFINMAVIGTFANWYNSGTDIDLSSAATVLEENFGA
AAKYIWGIGLLAAGQSSTLTGTLAGQFVMSGFVKMRVSKFKRAFITRAIAIVPAIVIAFI
ADDEDFNNYLNILQAIQLPFAVIPLLKLSMDRELMGEFTIGKVQLTLLSVLSAAIVGVNY
YASVPDEVNWSEAWIYIILVVMVLYFIFLGIVLFTKIKDTKDVKQSMLSNHKQSLIQDDE
QYHVKQ