Identifiers and Description

Gene Model Identifier

TTHERM_00001080

Standard Name

RAB4A

Aliases

PreTt11517 | 1.m00565

Description

RAB4A Rab-family small GTPase Rab4B; Rab II family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase-mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00009 ) Elongation factor Tu GTP binding domain
• ( PF00025 ) ADP-ribosylation factor family
• ( PF00071 ) Ras family
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF03029 ) Conserved hypothetical ATP binding protein
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_19228.1	4.0008150871967356e-141
	Description: Ras-like protein Rab-4A (214 aa)
Oxytricha	Contig13582.0.g55	4.0018838296491823e-56
	Description: Ras family
DictyBase	DDB_G0292406	6.998985483803218e-56
	Description: rab4 on chromosome: 6 position 1558648 to 1559514
WormBase	WBGene00004276	1.0004249259458435e-52
	Description: locus:rab-14 status:Confirmed UniProt:Q93874 protein_id:CAB01884.1
Tetrahymena borealis	EI9_00235.1	1.0004249259458435e-52
	Description: hypothetical protein (812 aa)
SGD	YER031C	6.997125142158947e-47
	Description: YPT31 Rab family GTPase, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi
Stentor Coeruleus	SteCoe_28945	1.185064864233981e-27
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00001080(coding)
ATGTAGGATTTTTACCCTAAAAAGAAGGAAGAATAGGTTGACACTCTTTTTAAATTCATA
ATAGTAGGAAATGCTTCATCAGGAAAGACATGCTTGTTACATTATTTTATAGAAGGAAAG
CCAAAATAAAATTCAACTTATACTATTGGTGTTGAATTTGGGTCTAAAATTGAAAAGGTT
GGATCAAAGCTAGTTAAATTTTAAATTTGGGATACTGCAGGATAGGAAAGATTTAGATCA
GTAGCACGCACATATTATAGGGGAGCAGTAGGAGCAGTAATCGTTTTTGATCTGACAAAC
ATAGATTCATTTCACTCACTTTAAAATTGGGTCAATGATGTTAGAGAATTAGCAAATAAG
GAAGTATGTATTGTAGTTTGTGGAAATAAATCTGATTTGACAGATGAACGTGCAGTTTAA
AGTCATGAAGCAAAACGTTAATGTGAAAGTCTAGATGTAGAATACATCGAAACAAGCGCA
TTAACTGGTGAAAATGTAAATGAAGCATTTTCTATTATAACTAAGACTATTTTGCAAAAA
ATAGAAAATAATTAAATGGAGCCTATTTTTTAACCGCGTCCATTTACACCTAAGCCTGAT
TAATTTGATATTGATAAACCTACAAAATGCAATTGTTGA

>TTHERM_00001080(gene)
ATGTAGGATTTTTACCCTAAAAAGAAGGAAGAATAGGTTGACACTCTTTTTAAATTCATA
ATAGTAGGAAATGCTTCATCAGGAAAGACATGCTTGTTACATTATTTTATAGAAGGAAAG
CGTAATTAATTACAAAATTTAAAGCAGACAATAATAAAATATGAATTTTAATTTGCCATT
TAATTGAAACAATAGATAGATTGATTAATATATGTTTATTTAGATTAAGCAAAACGCTAA
AAAAATTAAAATATTTATATATTTTAACAGCAAAATAAAATTCAACTTATACTATTGGTG
TTGAATTTGGGTCTAAAATTGAAAAGGTTGGATCAAAGCTAGTTAAATTTTAAATTTGGG
ATACTGCAGGATAGGAAAGATTTAGATCAGTAGCACGCACATATTATAGGGGAGCAGTAG
GAGCAGTAATCGTTTTTGATCTGACAAAGTAAAATATTAGTTAGAAATCAATAAATATTT
TGAAAATACAAGAAGAAATTATTTACATTTCATTCTAACCTTATTTTTTAATACTTATTT
CACAGCATAGATTCATTTCACTCACTTTAAAATTGGGTCAATGATGTTAGAGAATTAGCA
AATAAGGAAGTATGTATTGTAGTTTGTGGAAATAAATCTGATTTGACAGATGAACGTGCA
GTTTAAAGTCATGAAGCAAAACGTTAATGTGAAAGTCTAGATGTAGAATACATCGAAACA
AGCGCATTAACTGGTGAAAATGTAAATGAAGCATTTTCTATTATAACTAAGACTATTTTG
CAAAAAATAGAAAATAATTAAATGGGTAATAAATACTATTTAAAATAAATATTAATTGTT
AGATTTTATGAAATATTTTTTTTAAAATTAAATAATTTTATCTTTTATCATTTTTATTAA
AAGAGCCTATTTTTTAACCGCGTCCATTTACACCTAAGCCTGATTAATTTGATATTGATA
AACCTACAAAATGCAATTGTTGA

>TTHERM_00001080(protein)
MQDFYPKKKEEQVDTLFKFIIVGNASSGKTCLLHYFIEGKPKQNSTYTIGVEFGSKIEKV
GSKLVKFQIWDTAGQERFRSVARTYYRGAVGAVIVFDLTNIDSFHSLQNWVNDVRELANK
EVCIVVCGNKSDLTDERAVQSHEAKRQCESLDVEYIETSALTGENVNEAFSIITKTILQK
IENNQMEPIFQPRPFTPKPDQFDIDKPTKCNC