Identifiers and Description

Gene Model Identifier

TTHERM_00011180

Standard Name

APRT1 (adenine phosphoribosyltransferase1)

Aliases

PreTt11724 | 1.m00772

Description

adenine phosphoribosyltransferase; Phosphoribosyl transferase domain containing protein. D127N mutation confers 6-methylpurine (6mp) resistance.

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF00156 ) Phosphoribosyl transferase domain
  • ( TIGR00201 ) comF family protein
  • ( TIGR00336 ) orotate phosphoribosyltransferase
  • ( TIGR01090 ) adenine phosphoribosyltransferase
  • ( TIGR01744 ) xanthine phosphoribosyltransferase

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_02834.1 3.0002649496582814e-114
Description: phosphoribosyl transferase domain-containing protein (180 aa)
SGD YML022W 9.99893167504554e-35
Description: APT1 Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis
WormBase WBGene00020557 8.997017754360629e-34
Description: Adenine phosphoribosyltransferase status:Confirmed UniProt:P91455 protein_id:CCD62975.1
Oxytricha Contig672.0.g98 2.000470901975128e-28
Description: Phosphoribosyl transferase domain
DictyBase DDB_G0270174 2.0009605191578312e-25
Description: aprt on chromosome: 1 position 4368158 to 4368757

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:29570682: Akematsu T, Findlay A, Fukuda Y, Pearlman RE, Loidl J, Orias E, P Hamilton E (2018) Resistance to 6-Methylpurine is Conferred by Defective Adenine Phosphoribosyltransferase in Tetrahymena. Genes 9(4):

Sequences 

>TTHERM_00011180(coding)
ATGGATTACTAAAATTAAGAAATAGGTAAAGTTATTAGCGAAAACTTCAGAAATATTCCT
GATTTCCCTTAACCTGGTATTATCTTTAAAGATATTGCTCCTCTCCTCTCTAATCCTGCC
ATTTTTAAGCGTATTACTGATGCTTTTGTAATTGCTTTGAAGGACATTGATTTTGATAAA
ATTGTTATCTTAGAATCTAGAGGTTTTATTTTTGGAACCGCTATTGGTTTACAAATGGGA
AAGGGATTAATTTTAATCAGAAAGAAAGGCAAACTACCTGGTAAGGTTGAATAATTCTCA
TTCGACTTAGAATACGGTAAGGATGTTTTTGAAATTCAAAGTGATGCTTTAGCTAAAGGT
GAAAAAGTTGTTATTGTTGATGATATTCTAGCTACTGGTGGAACTGCTGATGCAGCTTGC
AGATTAGTTGAAAAGGTAGGAGGAGTAGTATAAGCTGTTATGTTCCTTTACCAAATTAAG
GATCTTAAGGGCGAAGAAAGATTATCTAAATACAAGGTTATTAATCTTCATATTGAATGA


>TTHERM_00011180(gene)
ATGGATTACTAAAATTAAGAAATAGGTAAAGTTATTAGCGAAAACTTCAGAAATATTCCT
GATTTCCCTTAACCTGGTATTATCTTTAAAGATATTGCTCCTCTCCTCTCTAATCCTGCC
ATTTTTAAGCGTATTACTGATGCTTTTGTAATTGCTTTGAAGGACATTGATTTTGATAAA
ATTGTTATCTTAGAATCTAGAGGTTTTATTTTTGGAACCGCTATTGGTTTACAAATGGGA
AAGGGATTAATTTTAATCAGAAAGAAAGGCAAACTACCTGGTAAGGTTGAATAATTCTCA
TTCGACTTAGAATACGGTAAGGATGTTTTTGAAATTCAAAGTGATGCTTTAGCTAAAGGT
GAAAAAGTTGTTATTGTTGATGATATTCTAGCTACTGGTGGAACTGCTGATGCAGCTTGC
AGATTAGTTGAAAAGGTAGGAGGAGTAGTATAAGCTGTTATGTTCCTTTACCAAATTAAG
GATCTTAAGGGCGAAGAAAGATTATCTAAATACAAGGTTATTAATCTTCATATTGAATGA


>TTHERM_00011180(protein)
MDYQNQEIGKVISENFRNIPDFPQPGIIFKDIAPLLSNPAIFKRITDAFVIALKDIDFDK
IVILESRGFIFGTAIGLQMGKGLILIRKKGKLPGKVEQFSFDLEYGKDVFEIQSDALAKG
EKVVIVDDILATGGTADAACRLVEKVGGVVQAVMFLYQIKDLKGEERLSKYKVINLHIE