Identifiers and Description

Gene Model Identifier

TTHERM_00011670

Standard Name

CDK3 (Cyclin-Dependent Kinase 3)

Aliases

PreTt11773 | 1.m00821

Description

cyclin-dependent kinase-like Serine/Threonine kinase family protein; Protein kinase domain containing protein; sequence similarity to the CRK7 subfamily of the protein kinase CDK family

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) Protein kinase domain
• ( PF02701 ) Dof domain, zinc finger
• ( PF07714 ) Protein tyrosine and serine/threonine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_02777.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (666 aa)
Oxytricha	Contig17113.0.g22	4.9995060293141384e-98
	Description: Protein kinase domain
DictyBase	DDB_G0273721	7.001141985045207e-89
	Description: cdk9-2 on chromosome: 2 position 3321422 to 3323747
WormBase	WBGene00007135	9.998074580622396e-81
	Description: locus:cdk-12 status:Partially_confirmed UniProt:C8JQR0 protein_id:CBB15981.1
SGD	YKL139W	8.997587713565275e-70
	Description: CTK1 Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3 end processing, and ribosomal protein Rps2p to increase translational fidelity; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13
Stentor Coeruleus	SteCoe_18197	1.0112214926104486e-43
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00011670(coding)
ATGGAAAAGAATAGCAATAGCCAGCAAAGTGGCTCTTAAACCGTTCCAATAAGAACTAGA
AATATAAGAAAGTATTATAGATTGATAGCAGAAGTTGGGTCAGGAACCTATGGTAGAGTT
TATAAGGCAGAATGTCTGCGAACTAAATAGTATGTTGCTCTCAAAAAATTCGAAAGCAAA
GATGATAAAATTAAAGAAGACGGATTTCCAATTACAGCAGTGCGTGAAATTCTTTTGCTA
AAATAATTAGACCATGTCAATATTATCAAATTAAGGGAAATTATTTTGTCAAAGCCTTCT
GAAAAAAACGACTACCGTGGTTCCACATTTTTAGTTTTTGATTACATGGATCACGATTTT
GCTGGATTGCATAGAAATAAACATGAATTTTCTCTTTAGGAGCTCAAATGCATCATGAAA
TAAATTCTATTAGGCGTACAATATCTTCACTATAAGAAAGTCATTCACAGAGACTTGAAA
ATAGCAAACATATTATATAACAATTAAGGAGAGGTTAAAATAGCTGATTTCGGTTTAGCA
AGATTGCTTAATCCAAACAATCCAAAGTATACAAATAAAGTAGTAACTCTCTGGTACAGA
GCTCCTGAGCTGCTTCTAGGAGCAAAGGAATATACAGAGCAAATTGACATGTGGAGTGTT
GGATGTATTTTCATTGAACTTGCAGTTGGTGAAAATTTACTTAGAGGTGAGAATGAGCCA
AGATAACTAGATAAAATCTATGAATTATGTGGCAGCCCCAACACCTAAAATTGGCCTGAA
GTCGACAAACTTCAGCTTTGGAAGGACATGAAACCCAAAAGAAATTTTGAAAGAAAACTT
AGAGAATAGGTGATTGAAAGAAAAAAAAATATTGATCCTTAGTTTTTAAATTTATTAGAT
GGGATTATGGTCTTGAATCCTAAGAAAAGATTTACTGTTCAATAATGTCTTGACCATGAA
TTCTTTAAAGTAGAACCTCTGCCTTTTGAAATTAGTGAAATGCCAAAAATAAAAGAAGAG
TGTCATGAAGCTCTTCTAAAAAATGTAAAAAATAGAAACCAAGTCATATAATCTCATAAA
AATAATTTCATGTAAAGAGCAAATATGTCTCCTTCTAGAATCCCTCCAATGAGCACCTAA
AATTAATAGGGATAAAAGTCATATTCCAGCTCTTAAAATTAATTGTCGTCAAATAAGTAA
AGCACAAGCAGTATATAAAATGCATCATCTTCATAATAAGGAAATTAGATAGTTGGATAG
TCTCACTTTGACTCCAGAAACAGTGGGAAAAGCCACTTTTAGTAAAAATAATAAAGTAGC
AGCAGCAATAGCAGCTAGTAATACTCAAGAGAACACATCAGCAATAGTAAGGGAGGCTAT
TATGGAAACTCAAATAATTCGAGTTCTATGAAATACACTAGCGGGGGTGCTTAGTAGAAT
ATTCCGTTAGACAGCGGGCCGAATCTTAAAAAGTAAGGCAGTTCTACAGTAGGATAAAAC
CAATAACAGTAATACCTAAACCCACCATATAAAAAGAAAACCAGCATTCAGCTTAGTGGG
GATAATAATAACGATTATCCATCAATTGAGCATCATTTGGATAACAGCAATAAAAGCGTC
ACTAACGAATCTCAAGTGGCTTAACCCAATTAAAGTTCTAAATTTAATTCATTTTCAGGG
CTTGCATCTCTTGTCTAAAAGTAAGGATCTGTTGATAGACAAGTGCATATCCCTCTGGAA
AACAGTGGTCACAAGAAGCAAGTAGAAGATGAAGATGATGACTATGAAAATTAATCAACA
GCTTAAGTCCATAAAAAATAAAGCAATCTCTCTATGCTCACAAGTAATGCATCTACCTTT
ATGTATAACAGCATCAATAATAATAACGATGATCCTATCATCAACCATCTTTCTAAAATT
AATCAAAAAAGATCACCTCCCTCAGAAATATACGATATAAATATTAAGAAAAAAATCAAA
GAAGACTGA

>TTHERM_00011670(gene)
ATGGAAAAGAATAGCAATAGCCAGCAAAGTGGCTCTTAAACCGTTCCAATAAGAACTAGA
AATATAAGAAAGTATTATAGATTGATAGCAGAAGTTGGGTCAGGAACCTATGGTAGAGTT
TATAAGGCAGAATGTCTGCGAACTAAATAGTATGTTGCTCTCAAAAAATTCGAAAGCAAA
GATGATAAAATTAAAGAAGACGGATTTCCAATTACAGCAGTGCGTGAAATTCTTTTGCTA
AAATAATTAGACCATGTCAATATTATCAAATTAAGGGAAATTATTTTGTCAAAGCCTTCT
GAAAAAAACGACTACCGTGGTTCCACATTTTTAGTTTTTGATTACATGGATCACGATTTT
GCTGGATTGCATAGAAATAAACATGAATTTTCTCTTTAGGAGCTCAAATGCATCATGAAA
TAAATTCTATTAGGCGTACAATATCTTCACTATAAGAAAGTCATTCACAGAGACTTGAAA
ATAGCAAACATATTATATAACAATTAAGGAGAGGTTAAAATAGCTGATTTCGGTTTAGCA
AGATTGCTTAATCCAAACAATCCAAAGTATACAAATAAAGTAGTAACTCTCTGGTACAGA
GCTCCTGAGCTGCTTCTAGGAGCAAAGGAATATACAGAGCAAGTAATATCAAAATAATTT
AAAACTAAATACACTACAAAATAATTTGGCTTATTTATTTACAGTGCAGCATATATTGAA
AGAATTAATAAGAAACATTAAAAGCATCTAACTTAGCCTTCTTATTAGCATATATTTAAA
GCTAACAGTCTAAAGTAGTATTTTCAAAAAATCAAACAAGCAAGTAAACAAACAAACAAA
GTTCCTGGCTAAAATAAAAAATATAATTTAGTTTTCCATTAAAAGTATTTTTCATACAAT
TTCAAAAGAAAAAAATTAGAAAAATGAAAATATTAAAAAAAAGTTAGCTATTTTTATAAA
AAATTCATTAAGATGAGCTTAAAAAAAATTATTACTATAAAGATTTCACTGTAATTTCAA
GCACAAAAAATAGAAAATAGCTTCAGAAAAAATAACTTTGTTTCTTAATTGATTTTAATT
GATAAATAGAAAAATAAATAACCTAAATATATATTAATTAATTAATTTATAATTATATTA
ATAAAAGATTGACATGTGGAGTGTTGGATGTATTTTCATTGAACTTGCAGTTGGTGAAAA
TTTACTTAGAGGTGAGAATGAGCCAAGATAACTAGATAAAATCTATGAATTATGTGGCAG
CCCCAACACCTAAAATTGGCCTGAAGTCGACAAACTTCAGCTTTGGAAGGACATGAAACC
CAAAAGAAATTTTGAAAGAAAACTTAGAGAATAGGTGATTGAAAGAAAAAAAAATATTGA
TCCTTAGTTTTTAAATTTATTAGATGGGATTATGGTCTTGAATCCTAAGAAAAGATTTAC
TGTTCAATAATGTCTTGACCATGAATTCTTTAAAGTAGAACCTCTGCCTTTTGAAATTAG
TGAAATGCCAAAAATAAAAGAAGAGTGTCATGAAGCTCTTCTAAAAAATGTAAAAAATAG
AAACCAAGTCATATAATCTCATAAAAATAATTTCATGTAAAGAGCAAATATGTCTCCTTC
TAGAATCCCTCCAATGAGCACCTAAAATTAATAGGGATAAAAGTCATATTCCAGCTCTTA
AAATTAATTGTCGTCAAATAAGTAAAGCACAAGCAGTATATAAAATGCATCATCTTCATA
ATAAGGAAATTAGATAGTTGGATAGTCTCACTTTGACTCCAGAAACAGTGGGAAAAGCCA
CTTTTAGTAAAAATAATAAAGTAGCAGCAGCAATAGCAGCTAGTAATACTCAAGAGAACA
CATCAGCAATAGTAAGGGAGGCTATTATGGAAACTCAAATAATTCGAGTTCTATGAAATA
CACTAGCGGGGGTGCTTAGTAGAATATTCCGTTAGACAGCGGGCCGAATCTTAAAAAGTA
AGGCAGTTCTACAGTAGGATAAAACCAATAACAGTAATACCTAAACCCACCATATAAAAA
GAAAACCAGCATTCAGCTTAGTGGGGATAATAATAACGATTATCCATCAATTGAGCATCA
TTTGGATAACAGCAATAAAAGCGTCACTAACGAATCTCAAGTGGCTTAACCCAATTAAAG
TTCTAAATTTAATTCATTTTCAGGGCTTGCATCTCTTGTCTAAAAGTAAGGATCTGTTGA
TAGACAAGTGCATATCCCTCTGGAAAACAGTGGTCACAAGAAGCAAGTAGAAGATGAAGA
TGATGACTATGAAAATTAATCAACAGCTTAAGTCCATAAAAAATAAAGCAATCTCTCTAT
GCTCACAAGTAATGCATCTACCTTTATGTATAACAGCATCAATAATAATAACGATGATCC
TATCATCAACCATCTTTCTAAAATTAATCAAAAAAGATCACCTCCCTCAGAAATATACGA
TATAAATATTAAGAAAAAAATCAAAGAAGACTGA

>TTHERM_00011670(protein)
MEKNSNSQQSGSQTVPIRTRNIRKYYRLIAEVGSGTYGRVYKAECLRTKQYVALKKFESK
DDKIKEDGFPITAVREILLLKQLDHVNIIKLREIILSKPSEKNDYRGSTFLVFDYMDHDF
AGLHRNKHEFSLQELKCIMKQILLGVQYLHYKKVIHRDLKIANILYNNQGEVKIADFGLA
RLLNPNNPKYTNKVVTLWYRAPELLLGAKEYTEQIDMWSVGCIFIELAVGENLLRGENEP
RQLDKIYELCGSPNTQNWPEVDKLQLWKDMKPKRNFERKLREQVIERKKNIDPQFLNLLD
GIMVLNPKKRFTVQQCLDHEFFKVEPLPFEISEMPKIKEECHEALLKNVKNRNQVIQSHK
NNFMQRANMSPSRIPPMSTQNQQGQKSYSSSQNQLSSNKQSTSSIQNASSSQQGNQIVGQ
SHFDSRNSGKSHFQQKQQSSSSNSSQQYSREHISNSKGGYYGNSNNSSSMKYTSGGAQQN
IPLDSGPNLKKQGSSTVGQNQQQQYLNPPYKKKTSIQLSGDNNNDYPSIEHHLDNSNKSV
TNESQVAQPNQSSKFNSFSGLASLVQKQGSVDRQVHIPLENSGHKKQVEDEDDDYENQST
AQVHKKQSNLSMLTSNASTFMYNSINNNNDDPIINHLSKINQKRSPPSEIYDINIKKKIK
ED