Identifiers and Description

Gene Model Identifier

TTHERM_00011710

Standard Name

CTH2 (CaTHepsin 2)

Aliases

PreTt11777 | 1.m00825

Description

CTH2 eukaryotic aspartyl protease

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• aspartic-type endopeptidase activity (IEA) | GO:0004190

Biological Process

• proteolysis (IEA) | GO:0006508

Domains

• ( PF00026 ) Eukaryotic aspartyl protease

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_02775.1	9.997093137033517e-262
	Description: eukaryotic aspartyl protease (481 aa)
WormBase	WBGene00000217	3.9998411574835458e-50
	Description: locus:asp-4 status:Confirmed UniProt:Q21966 protein_id:CAA90633.1
Tetrahymena borealis	EI9_17902.1	3.9998411574835458e-50
	Description: hypothetical protein (769 aa)
DictyBase	DDB_G0279411	6.001950283815408e-48
	Description: ctsD on chromosome: 3 position 2104523 to 2105867
SGD	YPL154C	1.0003292389192957e-45
	Description: PEP4 Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates
Oxytricha	Contig18588.0.g110	1.000159011384939e-43
	Description: Eukaryotic aspartyl protease
Stentor Coeruleus	SteCoe_11715	1.603810890548638e-28
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00011710(coding)
ATGAGAAAGATAAACAAATTATTGCTTATCATATCGCTACTTTTAATTGCAGGTTTTGCT
GCTAGACTTAAAAGGTCAAGCAAGTCAAAGCAGCAACAACTTATAGCTGATAGCATATAA
TCTTAAAACATGAAGATAACTCTCGAAAGAGATAACACTGTAGAAAAGAAGATTCAAATT
ATTAATTTTATTGAAGAATCTAACTCAATCAGAAAGAATTAGCCTTCATTCAAAAAGAGA
GTGTATGACAAGGATTCCTAAAAAATAATGATTGAAGAAAAGGAAATTACTGCTGACAGA
AAGCAATAATTTGTCTCTATGATACAAACTAATGGAAAAAGTGTAGGACTTTAGAATCAC
GGAAATACCTTTTATACTGGTAAAATATAAGTAGGTAATAGAGATCAATATTATAAGATG
ATATTTGACAGTGGTTCAACCCTTATTTTCTTGAATTCAGTTTAATGCGACAGTATTGGA
TGTATAAGAGGAAACTAATACGATTCTGAAGCATCTCCTACCTTCAAGGATGTTGACTTA
GAAGTAAAAGTTGAATTCGGAAGTGGTATCCTAACTGGTGAAATGGGAATAGATACTTTC
TATTTTGGTGATATGGCTGTTGAAAGAGTTGAATTCATGGAAATCTTAGAACAAGATGGT
GCTGTTTTTGAAAGTGGTGACTTTGATGGTTTGATTGGTTTAGCTTTTCCTTAATTAGGT
GATGGCGCTGACACTGTTGTTGATTACATGAAAGACTAGAATTTGATTCCTAAAAAGATG
TTCAGTTTCTACATGTCAAGAAAAGATGAGAGTGACAACTCTTTTATATCATTTGGATAA
ATTGATCAATAAGTTATAGCTGGAGATATTAAATACCATAAAGTAGAAAGTCCTTTATAT
TGGACTCTTCTAGCTTAAGAAATAAAACTTGGTGGACATAAAACTAGTCTTTGCTCTAGA
GAATATCCTTGTCCACTTGCCATAGATTCTGGAACAAGTATCATTGCTGGTCCATCTGAT
TAAATAGATTTCCTTACTGATCTTATTTTAGACAGAGGTTTTGAATGCAACTAAATCAAA
AAAATGCCAGCCATATCCTTTGTTATTGACGGAGAAGAATATCCTATATTAGCCGAGGAA
TACATTATTAGTTCTAATGGAGCTTTTGCTAATATGTATGAACACAGTGTAGATCCTGCT
GAGTGCTACCCTGCTTTAGTAGCATTAGATGTCGAAGAACCTTAACTTGGTCCTATGTGG
ATCCTTGGTGATATTTTTATGTCTAAGTATTACACTTTATTCAACCGTGAAGATAAAACT
GTAGGTTTTGCAAAGCTTAAAAGTATCGATACAAGGTTATATCAAAAGCCATCTAAAATT
GAAGATGAAGAATTTAATTATAACTTTATGAAAAAGATGAACAAAAGAAAAAAATCTAAA
AAACACCTTTGA

>TTHERM_00011710(gene)
ATGAGAAAGATAAACAAATTATTGCTTATCATATCGCTACTTTTAATTGCAGGTTTTGCT
GCTAGACTTAAAAGGTCAAGCAAGTCAAAGCAGCAACAACTTATAGCTGATAGCATATAA
TCTTAAAACATGAAGATAACTCTCGAAAGAGATAACACTGTAGAAAAGAAGATTCAAATT
ATTAATTTTATTGAAGAATCTAACTCAATCAGAAAGAATTAGCCTTCATTCAAAAAGAGA
GTGTATGACAAGGATTCCTAAAAAATAATGATTGAAGAAAAGGAAATTACTGCTGACAGA
AAGCAATAATTTGTCTCTATGATACAAACTAATGGAAAAAGTGTAGGACTTTAGAATCAC
GGAAATACCTTTTATACTGGTAAAATATAAGTAGGTAATAGAGATCAATATTATAAGATG
ATATTTGACAGTGGTTCAACCCTTATTTTCTTGAATTCAGTTTAATGCGACAGTATTGGA
TGTATAAGAGGAAACTAATACGATTCTGAAGCATCTCCTACCTTCAAGGATGTTGACTTA
GAAGTAAAAGTTGAATTCGGAAGTGGTAAATAACTATAAAAACTACTAAAAATTCTTTGA
TTGATTTACAAAACGCATATATATATATATATATATATATATATATTTATGCATAGAAAA
AAAACAAGAAAACAAGCAGACAAACAATCAATCAAAAGAAACTTACTTACAAATGAATAT
TCTACAATATCCTTTTAAACTTAAAATTATTTTTCATTATTTCAGGTATCCTAACTGGTG
AAATGGGAATAGATACTTTCTATTTTGGTGATATGGCTGTTGAAAGAGTTGAATTCATGG
AAATCTTAGAACAAGATGGTGCTGTTTTTGAAAGTGTAATTAATTATTTACTTTCATTAT
CTTTTTTTTAATTTTTCTATTACTGAATAACTTTGGAAAGAATATCTACTTATCTATCAA
TCAATACTTATAATTAATTCATTTGCTCATTAATTTTCATAAATATTGCTTAAAAAATAT
TTATGGAGACTGTTGATGAGTTAGTTAGTTATAAATTATTATTAGACGAAATCAATTTAA
GTTCAAATATAAAATTAAACAAAAAAATTTAAAAAAAATAGGGTGACTTTGATGGTTTGA
TTGGTTTAGCTTTTCCTTAATTAGGTGATGGCGCTGACACTGTTGTTGATTACATGAAAG
ACTAGAATTTGATTCCTAAAAAGATGTTCAGTTTCTACATGTCAAGAAAAGATGAGAGTG
ACAACTCTTTTATATCATTTGGATAAATTGATCAATAAGTTATAGCTGGAGATATTAAAT
ACCATAAAGTAGAAAGTCCTTTATATTGGACTCTTCTAGCTTAAGAAATAAAACTTGGTG
GACATAAAACTAGTCTTTGCTCTAGAGAATATCCTTGTCCACTTGCCATAGATTCTGGAA
CAAGTATCATTGCTGGTCCATCTGATTAAATAGATTTCCTTACTGATCTTATTTTAGACA
GAGGTTTTGAATGCAACTAAATCAAAAAAATGCCAGCCATATCGTAAGCATAATAAATTT
TAAATAGATTTATCCATTTATTCATTCATTGATTCCATCCAACACTTATTTTTCAGATCT
AATTAAATTGATCATAAATAAAAACCTCAAATAAAATGAAATATTTTTAATTAAATAATT
TAATTAGAATAAATATTTTTTCATTATTTTTAATTAATCATTTGAAAATTCGAATCTTTT
TGTATAGCAAGTTAAACTTTTTTTCATCCATCATATTTCCTATTAGAACTTTTGTAAGCA
AGCAAGCAATTAATTTCAAAATTCATTGTAAAAATCAAAAAATAAATAAATAAATTCTAA
ATTTAAGTTAACTCAGTTTTGAATACAAAAATAATTAATTAATAAATTTGTTTTTTTTTA
TGTTTATAATTTTTTTTTATAAAATATAAATTTTTTTGTTCATTATTCATAAACTTTTTA
AACAAATTAGCTTTGTTATTGACGGAGAAGAATATCCTATATTAGCCGAGGAATACATTA
TTAGTTCTAATGGAGCTTTTGCTAATATGTATGAACACAGTGTAGATCCTGCTGAGTGCT
ACCCTGCTTTAGTAGCATTAGATGTCGAAGAACCTTAACGTAATTAATAGATTGATTGCT
TAATTAGTGAAATTAATTTATCTTAAATTAAAATATTTAGTTGGTCCTATGTGGATCCTT
GGTGATATTTTTATGTCTAAGTATTACACTTTATTCAACCGTGAAGATAAAACTGTAGGT
TTTGCAAAGCTTAAAAGTATCGATACAAGGTTATATCAAAAGCCATCTAAAATTGAAGAT
GAAGAATTTAATTATAACTTTATGAAAAAGATGAACAAAAGAAAAAAATCTAAAAAACAC
CTTTGA

>TTHERM_00011710(protein)
MRKINKLLLIISLLLIAGFAARLKRSSKSKQQQLIADSIQSQNMKITLERDNTVEKKIQI
INFIEESNSIRKNQPSFKKRVYDKDSQKIMIEEKEITADRKQQFVSMIQTNGKSVGLQNH
GNTFYTGKIQVGNRDQYYKMIFDSGSTLIFLNSVQCDSIGCIRGNQYDSEASPTFKDVDL
EVKVEFGSGILTGEMGIDTFYFGDMAVERVEFMEILEQDGAVFESGDFDGLIGLAFPQLG
DGADTVVDYMKDQNLIPKKMFSFYMSRKDESDNSFISFGQIDQQVIAGDIKYHKVESPLY
WTLLAQEIKLGGHKTSLCSREYPCPLAIDSGTSIIAGPSDQIDFLTDLILDRGFECNQIK
KMPAISFVIDGEEYPILAEEYIISSNGAFANMYEHSVDPAECYPALVALDVEEPQLGPMW
ILGDIFMSKYYTLFNREDKTVGFAKLKSIDTRLYQKPSKIEDEEFNYNFMKKMNKRKKSK
KHL