Identifiers and Description

Gene Model Identifier

TTHERM_00016200

Standard Name

HHT4 (Histone H Three)

Aliases

PreTt11927 | 1.m00975

Description

HHT4 histone H3.4; histone H3.3, putative; Histone H3/CENP-A

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

  • prospore membrane spindle pole body attachment site (IEA) | GO:0070057

Molecular Function

Biological Process

  • cellular response to dopamine (IEA) | GO:1903351
  • donor selection (IEA) | GO:0007535
  • fibroblast growth factor receptor signaling pathway involved in mammary gland specification (IEA) | GO:0060595
  • germ-line processes downstream of sex determination signal (IEA) | GO:0007547
  • heme A biosynthetic process (IEA) | GO:0006784
  • heme biosynthetic process (IEA) | GO:0006783
  • inactivation of recombination (HML) (IEA) | GO:0007537
  • induction of apoptosis by extracellular signals (IEA) | GO:0008624
  • lateral sprouting from an epithelium (IEA) | GO:0060601
  • mammary gland specification (IEA) | GO:0060594
  • mammary placode formation (IEA) | GO:0060596
  • negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902642
  • negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
  • neutral lipid metabolic process (IEA) | GO:0006638
  • obsolete extracellular carbohydrate transport (IEA) | GO:0006859
  • obsolete mRNA endonucleolytic cleavage involved in unfolded protein response (IEA) | GO:0070055
  • obsolete regulation of nucleic acid-templated transcription (IEA) | GO:1903506
  • obsolete response to long exposure to lithium ion (IEA) | GO:0043460
  • ommochrome biosynthetic process (IEA) | GO:0006727
  • plant-type cell wall modification (IEA) | GO:0009827
  • positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
  • positive regulation of dendrite extension (IEA) | GO:1903861
  • propan-2-ol biosynthetic process (IEA) | GO:1902640
  • protein localization to old growing cell tip (IEA) | GO:1903858
  • regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902646
  • regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
  • regulation of bile acid metabolic process (IEA) | GO:1904251
  • regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
  • regulation of phosphorus utilization (IEA) | GO:0006795
  • response to methamphetamine hydrochloride (IEA) | GO:1904313
  • somatic processes downstream of sex determination signal (IEA) | GO:0007546
  • striated muscle myosin thick filament assembly (IEA) | GO:0071688
  • tertiary alcohol biosynthetic process (IEA) | GO:1902645
  • transcription by RNA polymerase V (IEA) | GO:0001060

Domains

  • ( PF00125 ) Core histone H2A/H2B/H3/H4

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

  • ( SD01377 ) Micronucleus: HHT4 is replaced by neo2
  • ( SD01378 ) Micronucleus: HHT4 is replaced by neo2
  • ( SD01858 )
  • ( SD02640 ) Micronucleus: HHT4 is replaced by neo2
  • ( SD02641 ) Micronucleus: HHT4 is replaced by neo2
  • ( SD02744 ) Micronucleus: neo2 into HHT4 Macronucleus: neo2 into HHT4

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:37024975: Nabeel-Shah S, Garg J, Ashraf K, Jeyapala R, Lee H, Petrova A, Burns JD, Pu S, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2023) Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation. Epigenetics & chromatin 16:10
  2. Ref:16908532: Cui B, Liu Y, Gorovsky MA (2006) Deposition and function of histone H3 variants in Tetrahymena thermophila. Molecular and cellular biology 26(20):7719-30

Sequences 

>TTHERM_00016200(coding)
ATGGTGATTCCTTTATTATAAACACTCTTTTTTTTTGAAAATAAGTTTATAATATTTTCA
AAACAAAATAAAATTAAATTAAAAAAATTTTCATCAAAACAAAAAAATAATTTACACAAA
ACAGAAAAGAAAATGGCTAGAACTAAATAAACTGCTAGAAAGTCAACTAGTATTAAGGCT
CCTAGAAAACAATTGGCTGCCAAGGCTGCCAGAAAGTCTGCCCCCATCTCTGGTGGTATC
AAAAAGCCCCATAAATTCAGACCTGGTACCGTTGCCTTGAGAGAAATCAGAAAGTATTAA
AAGACTACTGACTTACTTATTAGAAAGCTCCCCTTCTAAAGACTTGTCAGAGATATTGCT
ATGGAAATGAAGAGCGATATCAGATTCCAATCACAAGCTATCCTTGCCCTCCAAGAAGCT
GCTGAAGCCTACCTAGTAGGTTTATTCGAAGATACCAACCTCTGCGCTATCCACGCTAGA
AGAGTTACTATTATGACCAAGGATCTCCACCTTGCTAGAAGAATTAGAGGAGAAAGATTC
TGA



>TTHERM_00016200(gene)
CACTTTAAGCATATATTATTGATTAACTTACATAATTGGAATAGAAATGGTGATTCCTTT
ATTATAAACACTCTTTTTTTTTGAAAATAAGTTTATAATATTTTCAAAACAAAATAAAAT
TAAATTAAAAAAATTTTCATCAAAACAAAAAAATAATTTACACAAAACAGAAAAGAAAAT
GGCTAGAACTAAATAAACTGCTAGAAAGTCAACTAGTATTAAGGCTCCTAGAAAACAATT
GGCTGCCAAGGCTGCCAGAAAGTCTGCCCCCATCTCTGGTGGTATCAAAAAGCCCCATAA
ATTCAGACCTGGTACCGTTGCCTTGAGAGAAATCAGAAAGTATTAAAAGACTACTGACTT
ACTTATTAGAAAGCTCCCCTTCTAAAGACTTGTCAGAGATATTGCTATGGAAATGAAGAG
CGATATCAGATTCCAATCACAAGCTATCCTTGCCCTCCAAGAAGCTGCTGAAGCCTACCT
AGTAGGTTTATTCGAAGATACCAACCTCTGCGCTATCCACGCTAGAAGAGTTACTATTAT
GACCAAGGATCTCCACCTTGCTAGAAGAATTAGAGGAGAAAGATTCTGAGAGCTCTCTCT
AATAATTAACTTAATATATAATACACACATATAATATAATGTTTTCTTATTATGGGAATC
ATTTAGTTTGTTTTACATAATAACTAAATTATTTATTTAATATGAGGTTTTTAAAATAAA
TATTTATAAAATAAAATTTTTTTGAAAAAAACATTAGTTA



>TTHERM_00016200(protein)
MVIPLLQTLFFFENKFIIFSKQNKIKLKKFSSKQKNNLHKTEKKMARTKQTARKSTSIKA
PRKQLAAKAARKSAPISGGIKKPHKFRPGTVALREIRKYQKTTDLLIRKLPFQRLVRDIA
MEMKSDIRFQSQAILALQEAAEAYLVGLFEDTNLCAIHARRVTIMTKDLHLARRIRGERF