Identifiers and Description

Gene Model Identifier

TTHERM_00023980

Standard Name

RAN1 (RAN GTPase)

Aliases

Tt-ran | PreTt12011 | 1.m01059

Description

RAN1 GTP-binding nuclear protein Ran-1; Putative Ran GTPase; an evolutionarily conserved small GTPase with roles in nuclear transport- mitotic spindle assembly and nuclear envelope assembly

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

Domains

  • ( PF00009 ) Elongation factor Tu GTP binding
  • ( PF00025 ) ADP-ribosylation factor family
  • ( PF00071 ) Ras family
  • ( PF01926 ) GTPase of unknown function
  • ( PF08477 ) Miro-like protein
  • ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_13865.1 2.0007442334946695e-153
Description: Ras family protein (241 aa)
Oxytricha Contig21120.0.g73 3.001222955304439e-106
Description: Ras family
SGD YOR185C 7.003003394656772e-98
Description: GSP2 GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); Gsp1p homolog that is not required for viability
WormBase WBGene00004302 9.003233894748109e-95
Description: locus:ran-1 GTP-binding nuclear protein ran-1 status:Confirmed UniProt:O17915 protein_id:CAB07240.1
DictyBase DDB_G0291235 9.998285701479858e-93
Description: ranA on chromosome: 6 position 78789 to 80092
Stentor Coeruleus SteCoe_37736 5.0345753587649823e-45
Description: None

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:22594798: Liang H, Xu J, Zhao D, Tian H, Yang X, Liang A, Wang W (2012) Subcellular localization and role of Ran1 in Tetrahymena thermophila amitotic macronucleus. The FEBS journal 279(14):2520-33
  2. Ref:12787777: Quimby BB and Dasso M (2003) The small GTPase Ran: interpreting the signs. Curr Opin Cell Biol 15(3):338-44
  3. Ref:8026746: Nagata K, Takemasa T, Alam S, Hattori T, Watanabe Y, Nozawa Y (1994) Cloning of cDNAs encoding a cell-cycle-regulatory GTP-binding low-M(r) (GBLM) protein, Ran/TC4, from micronucleated Tetrahymena thermophila and amicronucleated Tetrahymena pyriformis. Gene 144(1):123-5

Sequences 

>TTHERM_00023980(coding)
ATGGTTGATAACAAGTAAAACGTTGTTGCTGAATTCAAGCTCGTCTTAGTTGGTGATGGT
GGTGTCGGTAAGACTACTTTCGTCACTAGACATCAAACTGGTGAATTCGAAAAGAGATAT
ATTGCCACCCAAGGTGTCAATGTTTCCAACATGGTCTTATACACCACTAAGGGTCCCATC
AGATTCAACATTTGGGATACTGCTGGTTAAGAAAAGCTCGGTGGTCTCCGTGAAGGTTAC
TACATTGGTGCCAACGCCGCTATCATGATGTTCGATGTCACCTCCAGAATTACTTATAAA
AATATTCCTAAGTGGCACAAGGATTTGACCAGAATCTGCGAAAATATTCCCATCGTTTTG
GTCGGTAACAAGGTTGACTCTAAGGACAGAAAGGTCAAGGCTAGACAAATCACTTTCCAC
AGAAAGAGATCCCTCTAATATTATGATGTCTCTGCTAAATCTAACTATTAATACGAAAAG
CCCTTCCTCTGGATCCTCAGAAAGCTCACCGGTGATCCCACCCTTAACCTCGTCGAAGGT
ATCGCTCTTGTTGCTCCTGATACTGAACACGTCATGACTGAAGATCAAATCAAGCAATTG
GAAATGGAACAAGCTGAAGCTATGAACCTCGCCCAACAAGGTGTCCTTCCTGATGATGAA
GATGATGAATTCAACTGA


>TTHERM_00023980(gene)
ATGGTTGATGTAAATAGTATTTTTTATTCTTTCTTTCTGGCTCAGGAACTGATCTTCAGT
TTTCTTGGATGATGGACACATAGTCTATGAACCTATCATGATTGTTTGTTGATCTCTTTC
CTAAGCCAGAGAGGATTGATTGTTTGCTAATACCTTATTGCTAAACTAACTTTTACAATT
TTAAAATAATAGAACAAGTAAAACGTTGTTGCTGAATTCAAGCTCGTCTTAGTTGGTGAT
GGTGGTGTCGGTAAGACTACTTTCGTCACTAGACATCAAACTGGTGAATTCGAAAAGAGA
TATATTGCCACCCAAGGTGTCAATGTTTCCAACATGGTCTTATACACCACTAAGGGTCCC
ATCAGATTCAACATTTGGGATACTGCTGGTTAAGAAAAGCTCGGTGGTCTCCGTGAAGGT
TACTAGTAATAATTTTTTTCAAACACTTATCATAAAATTTTTATCATTTGGACTAATTGA
TTGACTGACTGACTGATTAACAAGTTTGTTTGCTGAATAATTGCTTACAAGTCTAACTAG
CTCTTACTATAAATATTCCTTTAGGCTCTGTGTTTGTTCATAACATATAAATAGGAATGT
GAGTCATTCTTTCTTTCTATCTATTTTGTTTATGTTATCAAGCTACAAAGCAAGAGTTGA
TTGCTAAAAATAAGCAACAAGAAATAGAAAGATGATTATTAAATGGTATAAAAGGAATAG
CAGAGACCATCTACATTGATTAAGCCATAGCTTCTTACATTATAAGAAATTATAAAGAAA
GTAGGATGCATTTAGAGAAGATTTAGCTAGCGAAAACCCAATCTTTTGTGGTGATTTATT
TAGCGACGCAATTTAATTTAAAAAGAAAATTTAAAAACAAACTCAGTCTGTCAATCAGTC
AATCAATCAGTCAGTCAGTTCTTTGTTCGTTGAGACTCTTTTTTCATTTAAAAATGCTTA
AATCAATCTATTTAACGAATTTCTAATGAATTTATTTTTAACAATAGCATTGGTGCCAAC
GCCGCTATCATGATGTTCGATGTCACCTCCAGAATTACTTATAAAAATATTCCTAAGTGG
CACAAGGATTTGACCAGAATCTGCGAAAATATTCCCATCGTTTTGGTCGGTAACAAGGTT
GACTCTAAGGACAGAAAGGTCAAGGCTAGACAAATCACTTTCCACAGAAAGAGATCCCTC
TAATATTATGATGTCTCTGCTAAATCTAACTATTAATACGAAAAGCCCTTCCTCTGGATC
CTCAGAAAGCTCACCGGTGATCCCACCCTTAACCTCGTCGAAGGTATCGCTCTTGTTGCT
CCTGATACTGAACACGTCATGACTGAAGATCAAATCAAGCAATTGGAAATGGAACAAGCT
GAAGCTATGAACCTCGCCCAACAAGGTGTCCTTCCTGATGATGAAGATGATGAATTCAAC
TGA


>TTHERM_00023980(protein)
MVDNKQNVVAEFKLVLVGDGGVGKTTFVTRHQTGEFEKRYIATQGVNVSNMVLYTTKGPI
RFNIWDTAGQEKLGGLREGYYIGANAAIMMFDVTSRITYKNIPKWHKDLTRICENIPIVL
VGNKVDSKDRKVKARQITFHRKRSLQYYDVSAKSNYQYEKPFLWILRKLTGDPTLNLVEG
IALVAPDTEHVMTEDQIKQLEMEQAEAMNLAQQGVLPDDEDDEFN