Identifiers and Description

Gene Model Identifier

TTHERM_00024230

Standard Name

RAB52 (RAB GTPase 52)

Aliases

PreTt12036 | 1.m01084

Description

RAB52 small GTPase family Rab protein; Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase-mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00009 ) Elongation factor Tu GTP binding domain
• ( PF00025 ) ADP-ribosylation factor family
• ( PF00071 ) Ras family
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF03029 ) Conserved hypothetical ATP binding protein
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00231 ) small GTP-binding protein domain
• ( TIGR00650 ) GTP-binding conserved hypothetical protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
SGD	YFL038C	1.0004783691736523e-35
	Description: YPT1 Rab family GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
Oxytricha	Contig11247.0.g57	2.0003218023735366e-33
	Description: Ras family
Tetrahymena borealis	EI9_18305.1	9.99723014177113e-33
	Description: Ras family protein (212 aa)
DictyBase	DDB_G0284985	3.999374135750469e-31
	Description: rab1D on chromosome: 4 position 2756032 to 2757408
WormBase	WBGene00004273	2.0008113830639685e-30
	Description: locus:rab-10 status:Confirmed UniProt:Q94148 protein_id:CCD70773.1
Tetrahymena borealis	EI9_15804.1	2.0008113830639685e-30
	Description: 7 transmembrane receptor secretin family protein (328 aa)
Stentor Coeruleus	SteCoe_24985	0.000000000000001713908431542013
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00024230(coding)
ATGAGTAAGGTAGCAAATAGCAATGATAATAAAATACGCATTCTTTTTTGTGGAAATATA
AATGTTGGTAAGTCATGTATAATTTAAAGGTTAATTACCAATAATTTTATAGAAAACTAC
ACTCCTACAGTTGGAGTTGACTTTAGATCAATATATTATTAAATTAATTAAACAAAGGTC
TAAGTCAATCTATTAGATATTCCTGGATAGGATAGATATAATGCATTAACACTGTCTTAA
ATAAGAAATGTAGATGGAGTTGTCTTTGTCTATGATATTTCTGACATGGATTCTTTCACA
GATATTATAAATTGGTAATAAAAAATTTAAAGTGCAGCTCATGAAAATACTTTTTAAACT
CTTCTTGGAAATAAATGTGATTTATTAGATAGATAGGTGCCTTTCAATAAAGGATTAGAA
TTTGCAGAGTCTAAAAGTATGAATTTCTTTGAGACCTCAGCTAAAAATGGTAAAGATGTA
GTAAATTCAGTTCAGAGTTTAGCTCAAAAAATATTTTGTGAAAGGTTGATGAATTAAAAT
TAATAAAAAAATGATGAGAATGGCACAGTTAAGCTTTAAAAATCGAAACTAACCTTTCTA
AATTTTTTTAAGGGTGCTTATAATTACTATTGTTGA

>TTHERM_00024230(gene)
ATGAGTAAGGTAGCAAATAGCAATGATAATAAAATACGCATTCTTTTTTGTGGAAATATA
AATGTTGGTAAGTCATGTATAATTTAAAGGTTAATTACCAATAATTTTATAGAAAACTAC
ACTCCTACAGTTGGAGTTGACTTTAGATCAATATATTATTAAATTAATTAAACAAAGGTC
TAAGTCAATCTATTAGATATTCCTGGATAGGATAGATATAATGCATTAACACTGTCTTAA
ATAAGAAATGTAGATGGAGTTGTCTTTGTCTATGATATTTCTGACATGGATTCTTTCACA
GATATTATAAATTGGTAATAAAAAATTTAAAGTGCAGCTCATGAAAATACTTTTTAAACT
CTTCTTGGAAATAAATGTGATTTATTAGATAGATAGGTGCCTTTCAATAAAGGATTAGAA
TTTGCAGAGTCTAAAAGTATGAATTTCTTTGAGACCTCAGCTAAAAATGGTAAAGATGTA
GTAAATTCAGTTCAGAGTTTAGCTCAAAAAATATTTTGTGAAAGGTTGATGAATTAAAAT
TAATAAAAAAATGATGAGAATGGCACAGTTAAGCTTTAAAAATCGAAACTAACCTTTCTA
AATTTTTTTAAGGGTGCTTATAATTACTATTGTTGA

>TTHERM_00024230(protein)
MSKVANSNDNKIRILFCGNINVGKSCIIQRLITNNFIENYTPTVGVDFRSIYYQINQTKV
QVNLLDIPGQDRYNALTLSQIRNVDGVVFVYDISDMDSFTDIINWQQKIQSAAHENTFQT
LLGNKCDLLDRQVPFNKGLEFAESKSMNFFETSAKNGKDVVNSVQSLAQKIFCERLMNQN
QQKNDENGTVKLQKSKLTFLNFFKGAYNYYC