Identifiers and Description

Gene Model Identifier

TTHERM_00030430

Standard Name

PARP3 (Poly [ADP-Ribose] Polymerase 3)

Aliases

PreTt14274 | 2.m02191 | 3825.m02660

Description

PARP3 poly(ADP-ribose) polymerase family WGR domain protein; WGR domain containing protein; highly induced by replication stress

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• NAD+-protein poly-ADP-ribosyltransferase activity (IEA) | GO:0003950

Biological Process

• obsolete protein ADP-ribosylation (IEA) | GO:0006471

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_18135.1	9.997093137033517e-262
	Description: WGR domain-containing protein (614 aa)
Oxytricha	Contig12012.0.g59	3.9982216364827585e-104
	Description: Poly(ADP-ribose) polymerase catalytic domain
DictyBase	DDB_G0292820	1.9991716194688635e-85
	Description: adprt2 on chromosome: 6 position 2124835 to 2127096
WormBase	WBGene00004049	2.0001081030036656e-67
	Description: locus:pme-1 Poly(ADP-ribose) polymerase pme-1 status:Confirmed UniProt:Q9N4H4 protein_id:CCD73512.1
WormBase	WBGene00003916	2.0001081030036656e-67
	Description: locus:par-1 status:Partially_confirmed UniProt:Q9TW45 protein_id:CBL43447.1
Stentor Coeruleus	SteCoe_27180	1.4043787324419038e-54
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):
2. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_00030430(coding)
ATGCCACCTAAAAAAAATTAAAATAAGAGAAGCGGTAAAGATCGTTCTTTATCTCCTTAA
ACTGCTTCCGATGCAAAATAAGACCCTGTGAAAAAAGTTAAAGATGAAGTTTAAGATTTA
TAAGCTCCAGTTATTGTTAAAAGTAAATGTCCTGTTGACATGTAAGTTCCGGGTGCATCA
TCATACTAAGTATTGTAAATTGGTGACACTGTTTACAGTTTTACACTAAATTAAACTAAC
TGTGGGGCTAATAATAACAAATTTTATCTTGGATAGATACTCTATAATCCTACTGATTAA
AAATTTAGGACATTCTATAAATGGGGTAGAGTAGGAACTCCTGGCTAAAACTCTAATATA
CCATAAAATTCTTTAGAAAAGGCTATTTAAGATTATTAAAAGAAGAAAAATGATAAAATA
AAAGGTGGATATACTGAAATCTTTATAAAATATGGTGATGATGATAAAAATGATGAAGAA
GAAGAATAAAAGCAACAATAGAAACTTGAGGATAAGGAAAGAAAATAAAGTAAACTCTCT
GAGGCTGTTTAAATTATGATCAATGAAATTTTTGATTCTAAAATGATTTAAAATAGTATT
AAAGATATTGGTTTTGATTAAAAAAAGATGCCTTTAGGTAAATTAGCAGAGTAAACAATA
AAATAAGCCTATCTTGTTTTGAACGAACTTATGGAAGCCATCAAAAATAATGAAACTAGT
TAGTTTGAAAGACTTTCGAGCTCATTCTACTCATATATTCCTCATGATTTTGGCTTTTAA
AAAATGAGCCATTTTATTTTAAGATCTGAGGAATAAGTTAAGTAGAAGTTGGAAATGCTT
TAGAACTTAGAAGATCTTAAAATTGCTACTAACTTGTTAAAACTTACAGATACTGAGGAA
GCTATTATAGATGAAAATTATAAAAAACTAAAGTCTAATATTGAAGTTGTTAAAGATCAA
GATACTAGAAACATGATAATCAATTATATTAATGAGGGTTCAACTTATCGCTAACCTTAA
GTGTTAGAAATATACGAAGTAAATAGAGAAGGAGAAGATGAAAGATATACAAAAGATATA
GGAAACGATACACTTCTTTGGCATGGGTCTAGAATTTCTAACTTTGTCGGTATTCTTTCT
TAGGGACTTCGTATAGCACCTCCAGAAGCTCCAGTTTCAGGATATAACTATGGTAAGGGT
ATTTATTTAGCAGATATGTTTGATAAATCAAGATCATATTGCTAAGGAAACAGTCAAGGT
GTAAATTACATTATGCTTATTTAGGCTGCTTTAGGTAACCCGAACAGAATAGAAAGAACA
GATTACAATGCTAGTAATTTACCTTAAGGAACTAATTCCTGTTGGGGCTGGGGAACATTT
GGTCCTGAATAATTTATCACTCATAACGGTGTTAAAGTCCCTCATGGAAAGCCCGTTACG
ACCTAATCTAAGAATTATATGACTCACAATGAATTTATTATTTATAAAGTAGAATAAGCT
AAAATTAAATATTTAATTAGATTTAAATGA

>TTHERM_00030430(gene)
ATGCCACCTAAAAAAAATTAAAATAAGAGAAGCGGTAAAGATCGTTCTTTATCTCCTTAA
ACTGCTTCCGATGCAAAATAAGACCCTGTGAAAAAAGTTAAAGATGAAGTTTAAGATTTA
TAAGCTCCAGTTATTGTTAAAAGTAATCGTTATTAAAATTGATGTAGGAATTAGCAAAAC
ATATTTTATTTTTTTAGGTAAATGTCCTGTTGACATGTAAGTTCCGGGTGCATCATCATA
CTAAGTATTGTAAATTGGTGACACTGTTTACAGTTTTACACTAAATTAAACTAACTGTGG
GGCTAATAATAACAAATTTTATCTTGGATAGATACTCTATAATCCTACTGATTGTAAATT
ATTAAATAAATGTATGATTTATAGCTAAAAATATTTAAAGAAAAATTTAGGACATTCTAT
AAATGGGGTAGAGTAGGAACTCCTGGCTAAAACTCTAATATACCATAAAATTCTTTAGAA
AAGGCTATTTAAGATTATTAAAAGAAGAAAAATGATAAAATAAAAGGTGGATATACTGAA
ATCTTTATAAAATATGGTGATGATGATAAAAATGATGAAGAAGAAGAATAAAAGCAACAA
TAGAGTAAATATTTATAACTTTTTGTGATTGTTTTTGACACACAACAAATACAAGCTATT
AACATTTAGCATTAATTCCATCTTACTAATTCATTATTTACTTACTTATTTCTTTACTAA
ATAGAACTTGAGGATAAGGAAAGAAAATAAAGTAAACTCTCTGAGGCTGTTTAAATTATG
ATCAATGAAATTTTTGATTCTAAAATGATTTAAAATAGTATTAAAGATATTGGTTTTGAT
TAAAAAAAGATGCCTTTAGGTAAATTAGCAGAGTAAACAATAAAATAAGCCTATCTTGTT
TTGAACGAAGTATAAAAAGCTTAAAGATATTACTTTTTCATTTATTTTTTCATTTAAAAA
GCTTATGGAAGCCATCAAAAATAATGAAACTAGTTAGTTTGAAAGACTTTCGAGCTCATT
CTACTCATATATTCCTCATGATTTTGGCTTTTAAAAAATGAGCCATTTTATTTTAAGATC
TGAGGAATAAGTTAAGTAGAAGTTGGAAATGCTTTAGAACTTAGAAGATCTTAAAATTGC
TACTAACTTGTTAAAACTTACAGATACTGAGGAAGCTATTATAGATGAAAATTATAAAAA
ACTAAAGTCTAATATTGAAGTTGTTAAAGATGTAAACTTAATTAAATAAACTTTATGTAT
CATTTTAATTTTTTGATTTAATTAGCAAGATACTAGAAACATGATAATCAATTATATTAA
TGAGGGTTCAACTTATCGCTAACCTTAAGTGTTAGAAATATACGAAGTAAATAGAGAAGG
AGAAGATGAAAGATATACAAAAGATATAGGAAACGATACACTTCTTTGGCATGGGTCTAG
AATTTCTAACTTTGTCGGTATTCTTTCTTAGGGACTTCGTATAGCACCTCCAGAAGCTCC
AGTTTCAGGTAAGAATAAGTTTATTTTAAAATTATATTTATATTGATAAATAAACAAATA
AAAGGATATAACTATGGTAAGGGTATTTATTTAGCAGATATGTTTGATAAATCAAGATCA
TATTGCTAAGGAAACAGTCAAGGTGTAAATTACATTATGCTTATTTAGGCTGCTTTAGGT
AACCCGAACAGAATAGAAAGAACAGATTACAATGCTAGTAATTTACCTTAAGGAACTAAT
TCCTGTTGGGGCTGGGGAACATTTGGTCCTGAATAATTTATCACTCATAACGGTGTTAAA
GTCCCTCATGGAAAGCCCGTTACGACCTAATCTAAGGTAAAATTAATTATAAATATCTTA
AAACCTTTTAAAATGTTTATTTTTTAAAAAAAACCAAGAATTATATGACTCACAATGAAT
TTATTATTTATAAAGTAGAATAAGCTAAAATTAAATATTTAATTAGATTTAAATGA

>TTHERM_00030430(protein)
MPPKKNQNKRSGKDRSLSPQTASDAKQDPVKKVKDEVQDLQAPVIVKSKCPVDMQVPGAS
SYQVLQIGDTVYSFTLNQTNCGANNNKFYLGQILYNPTDQKFRTFYKWGRVGTPGQNSNI
PQNSLEKAIQDYQKKKNDKIKGGYTEIFIKYGDDDKNDEEEEQKQQQKLEDKERKQSKLS
EAVQIMINEIFDSKMIQNSIKDIGFDQKKMPLGKLAEQTIKQAYLVLNELMEAIKNNETS
QFERLSSSFYSYIPHDFGFQKMSHFILRSEEQVKQKLEMLQNLEDLKIATNLLKLTDTEE
AIIDENYKKLKSNIEVVKDQDTRNMIINYINEGSTYRQPQVLEIYEVNREGEDERYTKDI
GNDTLLWHGSRISNFVGILSQGLRIAPPEAPVSGYNYGKGIYLADMFDKSRSYCQGNSQG
VNYIMLIQAALGNPNRIERTDYNASNLPQGTNSCWGWGTFGPEQFITHNGVKVPHGKPVT
TQSKNYMTHNEFIIYKVEQAKIKYLIRFK