Identifiers and Description

Gene Model Identifier

TTHERM_00049070

Standard Name

CIT2 (CITrate synthase 2)

Aliases

PreTt11286 | 3.m01954 | 3824.m03044 | g19015

Description

CIT2 peroxisomal (Per) like protein; Putative citrate synthase; putative peroxisomal targeting signal peptide; possible product of a recent horizontal gene transfer event; Citrate synthase

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF00285 ) Citrate synthase, C-terminal domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:15170257: Mukai A, Endoh H (2004) Presence of a bacterial-like citrate synthase gene in Tetrahymena thermophila: recent lateral gene transfers (LGT) or multiple gene losses subsequent to a single ancient LGT? Journal of molecular evolution 58(5):540-9
  2. Ref:12025402: Kojima H, Numata O (2002) Enzymatic form and cytoskeletal form of bifunctional Tetrahymena 49kDa protein is regulated by phosphorylation. Zoological science 19(1):37-42
  3. Ref:11260259: Takeda T, Yoshihama I, Numata O (2001) Identification of Tetrahymena hsp60 as a 14-nm filament protein/citrate synthase-binding protein and its possible involvement in the oral apparatus formation. Genes to cells : devoted to molecular & cellular mechanisms 6(2):139-49
  4. Ref:9443816: Kojima H, Watanabe Y, Numata O (1997) The dual functions of Tetrahymena citrate synthase are due to the polymorphism of its isoforms. Journal of biochemistry 122(5):998-1003
  5. Ref:9268687: Takeda T, Watanabe Y, Numata O (1997) Direct demonstration of the bifunctional property of Tetrahymena 14-nm filament protein/citrate synthase following expression of the gene in Escherichia coli. Biochemical and biophysical research communications 237(2):205-10
  6. Ref:8575889: Numata O (1996) Multifunctional proteins in Tetrahymena: 14-nm filament protein/citrate synthase and translation elongation factor-1 alpha. International review of cytology 164( ):1-35
  7. Ref:8537311: Kojima H, Chiba J, Watanabe Y, Numata O (1995) Citrate synthase purified from Tetrahymena mitochondria is identical with Tetrahymena 14-nm filament protein. Journal of biochemistry 118(1):189-95
  8. Ref:7737352: Numata O, Yasuda T, Watanabe Y (1995) Tetrahymena intramitochondrial filamentous inclusions contain 14-nm filament protein/citrate synthase. Experimental cell research 218(1):123-31
  9. Ref:7592552: Takeda T, Kurasawa Y, Watanabe Y, Numata O (1995) Polymerization of highly purified Tetrahymena 14-nm filament protein/citrate synthase into filaments and its possible role in regulation of enzymatic activity. Journal of biochemistry 117(4):869-74
  10. Ref:8108567: Numata O (1994) [Multifunctional proteins in Tetrahymena--14 nm filament protein and EF-1 alpha]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 39(2):106-18
  11. Ref:1385189: Kurasawa Y, Numata O, Katoh M, Hirano H, Chiba J, Watanabe Y (1992) Identification of Tetrahymena 14-nm filament-associated protein as elongation factor 1 alpha. Experimental cell research 203(1):251-8
  12. Ref:1993043: Numata O, Takemasa T, Takagi I, Hirono M, Hirano H, Chiba J, Watanabe Y (1991) Tetrahymena 14-nm filament-forming protein has citrate synthase activity. Biochemical and biophysical research communications 174(2):1028-34
  13. Ref:6401983: Fabregat I, Satrústegui J, Machado A (1983) Citrate synthase of Tetrahymena pyriformis: evolutionary and regulatory aspects. Archives of biochemistry and biophysics 220(2):354-60

Sequences 

>TTHERM_00049070(coding)
ATGGAAAGAATTACTGATCTCAATTAATAAATTATCACTAACGAAACTGGTGAAAAGGAA
TACTACACAGTCACAGATAATAGAAATGGCAAAACTTATGAAGTTCCTATCAGAAACTCT
AGAGAAGGAAGATATATAATGGCTAAGGATATTGGTAAAATTAAAGATGCTGAAGGAAAT
GTCCTCCGTGTCTACGATCCTGGTTATATGAACACTATTGTTAATACTTCCAGAATTTGC
TATATTGATGGTGACTTGGGTGTATTAGAGTATAGAGGTATTCCAATTGAGTAGCTTGCT
GAGAAATCTACTTTCTTGGAAGTAGCTTATCTTCTTATCTACGGAGAATTACCAACCAAG
ACCCAATTTGAAGAATTCAACTAAAGAATTTCAGGTCACACATTCTTGCATACTGATGTC
TTACAAATGATGAAACACTTCAGATATGATGCTCATCCTATGGGTATGCTTATTAGCACT
ATTGCAGCATTATCTACTTTCCGTCCTGGTTCCAACCCTGCCTTAGCTGGTTAAGATATC
TATAAGGACTTGAAGATTCGTAACAAATAAATTTATCGTATTCTTGGACAAGTTCCTACT
ATTGCTGCTAACGCTTATAGATCTCGTATTGGTAGAAACTTCAACAACCCATCTTCTGAT
CTTCCTTACGTTGATAACTTCCTTTACATGATGGATAAATTAAATGAAAATAAATACAAG
CCTCATCCTAAGTTAGCTAAGGCTTTGGATATTCTCTTTATTCTCCATGCTGAACACGAA
ATGAATTGCTCAACAGCATTTGTTAGACATTTAGCTTCTTCTGGTGTTGATGTATACTCT
TGCATAGCTGGTTCTGCTGCTGCTCTTTATGGTCCTAAGCATGGTGGTGCAAATGAAGCC
GTTTTAAGAATGCTTGAATAAATTGGTGATGTTAAGAATATTCCCTCTTTCATTGATAAG
GTCAAGAATAGAAAGGCTTTACTTTTCGGTTTTGGTCACAGAGTCTATAAGAACTACGAC
CCTCGTGCTAAAATCGTCAAGAAGACTGCTTATGAAGTTTTTGAAATCTGTGGAAAAGAA
CCTTTAATTGAAATTGCCATCGAATTGGAAAAGATAGCTCTTGAAGATGAATTTTTCATT
AAGAGAAAGTTATATCCAAATGTTGATTTCTACTCTGGTGTTATTTATAGAGCTATGGGT
TTCCCCACTGATATGTTCCCAGTCCTTTTCACTATTCCAAGAGTTGCTGGTTGGTTAGCT
CATTGGGTTGAATACCTCGATGATAAGGAAAACAACATTGTTAGACCCAGACAAAACTAT
GTTGGCTATGCTAAAAGAGATTATGTTCCTATGGAATAAAGACAAGAAGCTAAATTTAAC
TTAGAAAGCTCCAAGAGTTCTACTTCCAAGAGAAGAGAAGCTGGTACAAGCGTTGTTTTG
TGA



>TTHERM_00049070(gene)
TTATTTTGAAAGAATAAAGAAATTAAAAAAAACTAATAACAATTACCGAAAAAAAAAGAA
AAAAACAGCAAAAAGCGAAGTGGGAATGGAAAGAATTACTGATCTCAATTAATAAATTAT
CACTAACGAAACTGGTGAAAAGGAATACTACACAGTCACAGATAATAGAAATGGCAAAAC
TTATGAAGTTCCTATCAGAAACTCTAGAGAAGGAAGATATATAATGGCTAAGGATATTGG
TAAAATTAAAGATGCTGAAGGAAATGTCCTCCGTGTCTACGATCCTGGTTATATGAACAC
TATTGTTAATACTTCCAGAATTTGCTATATTGATGGTGACTTGGGTGTATTAGAGTATAG
AGGTATTCCAATTGAGTAGCTTGCTGAGAAATCTACTTTCTTGGAAGTAGCTTATCTTCT
TATCTACGGAGAATTACCAACCAAGACCCAATTTGAAGAATTCAACTAAAGAATTTCAGG
TCACACATTCTTGCATACTGATGTCTTACAAATGATGAAACACTTCAGATATGATGCTCA
TCCTATGGGTATGCTTATTAGCACTATTGCAGCATTATCTACTTTCCGTCCTGGTTCCAA
CCCTGCCTTAGCTGGTTAAGATATCTATAAGGACTTGAAGATTCGTAACAAATAAATTTA
TCGTATTCTTGGACAAGTTCCTACTATTGCTGCTAACGCTTATAGATCTCGTATTGGTAG
AAACTTCAACAACCCATCTTCTGATCTTCCTTACGTTGATAACTTCCTTTACATGATGGA
TAAATTAAATGAAAATAAATACAAGCCTCATCCTAAGTTAGCTAAGGCTTTGGATATTCT
CTTTATTCTCCATGCTGAACACGAAATGAATTGCTCAACAGCATTTGTTAGACATTTAGC
TTCTTCTGGTGTTGATGTATACTCTTGCATAGCTGGTTCTGCTGCTGCTCTTTATGGTCC
TAAGCATGGTGGTGCAAATGAAGCCGTTTTAAGAATGCTTGAATAAATTGGTGATGTTAA
GAATATTCCCTCTTTCATTGATAAGGTCAAGAATAGAAAGGCTTTACTTTTCGGTTTTGG
TCACAGAGTCTATAAGAACTACGACCCTCGTGCTAAAATCGTCAAGAAGACTGCTTATGA
AGTTTTTGAAATCTGTGGAAAAGAACCTTTAATTGAAATTGCCATCGAATTGGAAAAGAT
AGCTCTTGAAGATGAATTTTTCATTAAGAGAAAGTTATATCCAAATGTTGATTTCTACTC
TGGTGTTATTTATAGAGCTATGGGTTTCCCCACTGATATGTTCCCAGTCCTTTTCACTAT
TCCAAGAGTTGCTGGTTGGTTAGCTCATTGGGTTGAATACCTCGATGATAAGGAAAACAA
CATTGTTAGACCCAGACAAAACTATGTTGGCTATGCTAAAAGAGATTATGTTCCTATGGA
ATAAAGACAAGAAGCTAAATTTAACTTAGAAAGCTCCAAGAGTTCTACTTCCAAGAGAAG
AGAAGCTGGTACAAGCGTTGTTTTGTGAGAAATTTAAATATTTAAAATATATAATAATAT
AATCTTATACTTCTAACCTCCATTATATCAAATGTATTCTATATTTTATATACTTTTTAT
TTTCTTCTAACTCATAAGATTTATCTACT



>TTHERM_00049070(protein)
MERITDLNQQIITNETGEKEYYTVTDNRNGKTYEVPIRNSREGRYIMAKDIGKIKDAEGN
VLRVYDPGYMNTIVNTSRICYIDGDLGVLEYRGIPIEQLAEKSTFLEVAYLLIYGELPTK
TQFEEFNQRISGHTFLHTDVLQMMKHFRYDAHPMGMLISTIAALSTFRPGSNPALAGQDI
YKDLKIRNKQIYRILGQVPTIAANAYRSRIGRNFNNPSSDLPYVDNFLYMMDKLNENKYK
PHPKLAKALDILFILHAEHEMNCSTAFVRHLASSGVDVYSCIAGSAAALYGPKHGGANEA
VLRMLEQIGDVKNIPSFIDKVKNRKALLFGFGHRVYKNYDPRAKIVKKTAYEVFEICGKE
PLIEIAIELEKIALEDEFFIKRKLYPNVDFYSGVIYRAMGFPTDMFPVLFTIPRVAGWLA
HWVEYLDDKENNIVRPRQNYVGYAKRDYVPMEQRQEAKFNLESSKSSTSKRREAGTSVVL