Identifiers and Description

Gene Model Identifier

TTHERM_00052180

Standard Name

MITS1 (MED31-interacting Tetrahymena specific protein 1)

Aliases

PreTt11398 | 3.m01834 | 3824.m03152

Description

MITS1 Possible subunit of Tetrahymena Mediator complex; Co-purified with Med31 in AP-MS experiments; hypothetical protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• alpha6-beta4 integrin-Shc-Grb2 complex (IEA) | GO:0070333
• sigma factor antagonist complex (IEA) | GO:1903865

Molecular Function

• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 17alpha-hydroxyprogesterone binding (IEA) | GO:1903880
• arsenate reductase (glutaredoxin) activity (IEA) | GO:0008794
• carboxymethylenebutenolidase activity (IEA) | GO:0008806
• delta5-delta2,4-dienoyl-CoA isomerase activity (IEA) | GO:0008416
• G protein-coupled serotonin receptor binding (IEA) | GO:0031821
• interleukin-13 receptor activity (IEA) | GO:0016515
• Kdo2-lipid IVA acyltransferase activity (IEA) | GO:0008913
• lactaldehyde reductase activity (IEA) | GO:0008912
• obsolete hydrogen-/sodium-translocating ATPase activity (IEA) | GO:0015442
• obsolete protein tagging activity (IEA) | GO:0008638
• obsolete sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity (IEA) | GO:0052591
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• obsolete tachykinin (IEA) | GO:0008648
• obsolete tocotrienol omega-hydroxylase activity (IEA) | GO:0052872
• oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor (IEA) | GO:0052592
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• rRNA methyltransferase activity (IEA) | GO:0008649
• Ser(Gly)-tRNA(Ala) hydrolase activity (IEA) | GO:0043908
• type 4 neuropeptide Y receptor binding (IEA) | GO:0031844

Biological Process

• 3-keto-sphinganine metabolic process (IEA) | GO:0006666
• cellular response to vanadate(3-) (IEA) | GO:1902439
• compound eye morphogenesis (IEA) | GO:0001745
• detection of stimulus involved in Dma1-dependent checkpoint (IEA) | GO:1902419
• embryonic brain development (IEA) | GO:1990403
• fibroblast growth factor receptor signaling pathway (IEA) | GO:0008543
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• induction of apoptosis by extracellular signals (IEA) | GO:0008624
• insect visual primordium formation (IEA) | GO:0001744
• intraciliary anterograde transport (IEA) | GO:0035720
• lipoxin A4 metabolic process (IEA) | GO:2001302
• lipoxin B4 metabolic process (IEA) | GO:2001304
• lipoxin metabolic process (IEA) | GO:2001300
• low-density lipoprotein particle mediated signaling (IEA) | GO:0055096
• maintenance of left sidedness (IEA) | GO:0061969
• mitotic cytokinetic cell separation (IEA) | GO:1902409
• molting cycle process (IEA) | GO:0022404
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902642
• negative regulation of chemokine-mediated signaling pathway (IEA) | GO:0070100
• negative regulation of endoplasmic reticulum tubular network organization (IEA) | GO:1903372
• negative regulation of interleukin-17-mediated signaling pathway (IEA) | GO:1903882
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• negative regulation of phospholipid translocation (IEA) | GO:0061093
• neutral lipid metabolic process (IEA) | GO:0006638
• obsolete bent DNA binding (IEA) | GO:0006326
• obsolete loss of asymmetric budding (IEA) | GO:0007122
• obsolete primary charge separation (IEA) | GO:0009766
• ommochrome biosynthetic process (IEA) | GO:0006727
• PEP carboxykinase C4 photosynthesis (IEA) | GO:0009764
• phagocytosis (IEA) | GO:0006909
• phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene (IEA) | GO:0018956
• photosynthetic NADP+ reduction (IEA) | GO:0009780
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of cardiac ventricle formation (IEA) | GO:1904944
• positive regulation of deacetylase activity (IEA) | GO:0090045
• positive regulation of direction of cell growth (IEA) | GO:0061390
• positive regulation of I-kappaB phosphorylation (IEA) | GO:1903721
• positive regulation of plant epidermal cell differentiation (IEA) | GO:1903890
• positive regulation of turning behavior involved in mating (IEA) | GO:0061095
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• prostate induction (IEA) | GO:0060514
• protein localization to old growing cell tip (IEA) | GO:1903858
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902646
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
• regulation of dendrite extension (IEA) | GO:1903859
• regulation of PERK-mediated unfolded protein response (IEA) | GO:1903897
• regulation of phosphatidate phosphatase activity (IEA) | GO:1903730
• regulation of phosphorus utilization (IEA) | GO:0006795
• response to curcumin (IEA) | GO:1904643
• response to osmotic stress (IEA) | GO:0006970
• response to oxidative stress (IEA) | GO:0006979
• stilbene biosynthetic process (IEA) | GO:0009811
• tertiary alcohol biosynthetic process (IEA) | GO:1902645
• toluene-containing compound metabolic process (IEA) | GO:0072490
• vacuolar acidification (IEA) | GO:0007035

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:31280994: Garg J, Saettone A, Nabeel-Shah S, Cadorin M, Ponce M, Marquez S, Pu S, Greenblatt J, Lambert JP, Pearlman RE, Fillingham J (2019) The Med31 Conserved Component of the Divergent Mediator Complex in Tetrahymena thermophila Participates in Developmental Regulation. Current biology : CB 29(14):2371-2379.e6

Sequences

>TTHERM_00052180(coding)
ATGGATAAAATTGAGTACTCACTTTATAAAGTTTGTTCTAAAATCATTGCACATACTCAA
AATGAACTCCCAACTTAGCAAAATGTTCACGACAATACTTAAGCAAAAGATTTATGTGAT
TCCGTTATGCTAAAATTTAATGAATTCGATCAGCTTTTCGATAGATTAACAAATATTGTT
TAATATTTGCAATACGATTAGCCTGAAGAGAAGAAAATGATAGATATTGAGAGATAGATT
TAAGAACATCAAAATGAAATTTGGAATTGTGGTGAAAATTTAAATAAACTGCATCACGAA
TTCATTAATAGTCCTTGGGTAAATATGGAAAGTGTTAATTTAATGTATGGAAGAAATGGT
TAAGTTAAAATGGAGTTATTGGATGGGTATAATTTAGGGATGGACTACAAAACTAAACAA
TAGGAGAAAAAACATTTAATGAGAAAAAAGCTTTTAAGCATGAAAAAACCTCCAAAAGTA
GATAAAATAAAGCTTAAAGATGATAGATGTATTGTGAAAACAGATATATACTAAATAAAC
TATGATTTAATTTATGACTAAGAAACTGATACTTTCAATTGGAAAATCCCTAGAACAAAG
GATATTTAGATATCTGATAATGGTTTATCATATTTGTAAAACTTCCTAAAAGATGAAAAA
AGTAAAAAGGATATTTAAACTGCTTTGGATCAGGTTAACAAATCTATAATTCAATTAAAA
AAAGAAATAATTGCTTAGACTAAAGAAAGAAAGAAGCGCTAGTAATTGTTTGAAGCTAAG
AAGGAGGTGTAGGAAGACCTTATTAAAACAGAGCACTTCAATGTTAAATAAGAGGCATAA
TCTTAAAATGTAAAATTAGAACATTATTCGTAACCTATGAATGTGAAATCCGAATATAAA
GGAAATGATGCTTTAGCTGAAGATAGTAATATTGAAGAAGAATACAACTACTAGATACTT
TGCAATAAATATGAGATGATGGTTTCTTATGTATTTTGCTTTATAGATTAGAAAATTAAA
ACCTTATTCTCAGATTAAGTTTTGGAGATTTTATAGAAATAGGACAAAGAAAACTTACAA
AAAAAATTTGGGCCAGAGGTTGTTTATCTTCAAAAAAAATCTGACATTAAAGATGAATTG
AAATTCAACTACGTATAGATTCGTTTCAAGCCTTAAACTGCGATGCTTTAAACTGTCTTA
AAATAGGAGAATTTGATCAAAAACAAAGCAGAAAATAATATCACATAAACATCAATTTTC
ATAGAACACATTTCTTACGACACTAATACCTACTATTAATTTATACTTTCCTAAGAGAAA
ATTAATTTTTATCGTTAAATTAGAGCTAAATCTCATTAAGAGCAAAAGGAAATTATTGAA
AAAATACAATATTATAAACCAAGCCAATTAATTAAGGAAAAAATTAACTATAAGAATTTA
ATTATTTAAGAAGCTATCAAAAATGATTTGCTTCCTAAATAAAGTTTCTCTTTAACACCG
TTCGATACTATTTACATTAAATCTAATATTACCCTCAGCTAAATTGACTCTACTCTACTG
AGGCCTTTCATAAATTTGGAGGACTAAAATTAAATTTAGGTGGATTCTTTATTTTTAATT
CATAAACCCAAAGAATTAATAATTTAACCAGAAAATGTAGATAATCCTTCAAACTCTGAT
AACGTGAGTTATTTAAGAGTTGTGATAGGAGATAAAATAGATTTAGAAATTATACTCTAG
TAGTACAGAGTAATCATGCTTTAGCAATTTTTTATTTCAAACTATAAGCTAAGCTAGAGT
CTGCATGATGAAAATTCAATGCATTTAGAAGTTTATGATGAATAGTAAGCTAGCAACATG
GTTTTACTAATTAGACAAAAAAGATAGTTATATGATGAGGACATTAAATAAATTAGTATA
AACAAAATATAAAGCAAGTATTTAACCCAAGCTGTATTTTAGCTTTAAAATCATCCTCTA
ATAAAAAACATAATCTACTAGGTCTTGATTTGTGTTAGGATAACCTGTGATGACCTAGAC
AGTAAAGACGATAAGGAGATATACTAAATAATAATACCATATCTGACAGATAAGCAGCAC
TACATAATTTATAATAGTTTAAACGAAGATATTATTGAATTAGATTCATAAAAGGAGCAA
GAATTAGATGAATTGATATAGGATTTGCAAAGAAAAGAGCATATTATTTAGAATTTTGTA
AACACTGTTTATATAGCACAAGCTGTTTAAAAAAATATTTTGCACTCCTAATTTAGAGCA
ATAAGTTAGGAATAAAACAGCGACTACAGTTAAATTACTATTGAGTGTAGATTAAAAGAT
GAGTTAAATTCAGATAAGCCAATTAAAATTTACATATAAAAAAACTTTCATATAAATTTG
GAATATAACTTTGGTGAATTGAGAAACTAATGCAAAACAGAGGAAATACCGAGAAACTAA
AGTTTATCTAGCTTCTACAAACAATTCACTTTTAATTTAGATTTAAATATCTAAAAATCA
TTGAAAGATATATATTCCAGGTATAATTACTTGAGTGATGATAGAACAAGGATTATAAAA
GAATTCCTCAAATTGAAAATTTCAAATGATGAATGGTTTACTCAACACAATTTGAAAACT
AGACCTGAAACTATTGTACATCACCCTAATTAGCAACACACAGGAAGTAATTAAGGTATA
TAACAAGGAATTAACGGTTAATAGAATGGTTTAAATCATTATAATCAATAAAGGCCAAAT
TAAAACCAATTCTAAAATAATTCTATATAGTAATAAAATAACTCTTAGGGTTTACCAGCA
AATCAGTAAGTAGTGGGTTAAGGAAATCATTAATAATCTGGAAATCAATAACGCCCATAT
GCTTAGAATTCTAATTTTAATCAATAATAATAACCCTAATAGTCATAACCTGGGACATAA
GTTTAATAAAATGGAGCTATGAATAATAGTTATGGTTAGCAAACAGGATAATCTACCTAA
AGAAATCCTTAACAGTATTACTAAAATTAATAATAGTATGGAAATAATAATTACAATAAT
TAAGCATAATAGCAATAAAATCCTAACTAATAAGGTGTTGGCTAGTAATCTGGTGCAAAT
AATTATGCTCACATGAATGGAGCTTAGAACTCTTCGTATAACTAGTAATAATATTAAAAT
TACCAACCAAATAGTAACAGACCTAATTGA

>TTHERM_00052180(gene)
TTGTCTCTCTATTTTATATATATTCCTAAAATAAATTATTATCAATTCTTTAATATATTA
ATTTCTAGAAGAAAAAGTTTTTATTTATTTAAACAATATTTTATTAATTCATAGTTTTAG
ACTTAATTTTACTTACGTTAGTTTAAGCGAATGGATAAAATTGAGTACTCACTTTATAAA
GTTTGTTCTAAAATCATTGCACATACTCAAAATGAACTCCCAACTTAGCAAAATGTTCAC
GACAATACTTAAGCAAAAGATTTATGTGATTCCGTTATGCTAAAATTTAATGAATTCGAT
CAGCTTTTCGATAGATTAACAAATATTGTTTAATATTTGCAATACGATTAGCCTGAAGAG
AAGAAAATGATAGATATTGAGAGATAGATTTAAGAACATCAAAATGAAATTTGGAATTGT
GGTGAAAATTTAAATAAACTGCATCACGAATTCATTAATAGTCCTTGGGTAAATATGGAA
AGTGTTAATTTAATGTATGGAAGAAATGGTTAAGTTAAAATGGAGTTATTGGATGGGTAT
AATTTAGGGATGGACTACAAAACTAAACAATAGGAGAAAAAACATTTAATGAGAAAAAAG
CTTTTAAGCATGAAAAAACCTCCAAAAGTAGATAAAATAAAGCTTAAAGATGATAGATGT
ATTGTGAAAACAGATATATACTAAATAAACTATGATTTAATTTATGACTAAGAAACTGAT
ACTTTCAATTGGAAAATCCCTAGAACAAAGGATATTTAGATATCTGATAATGGTTTATCA
TATTTGTAAAACTTCCTAAAAGATGAAAAAAGTAAAAAGGATATTTAAACTGCTTTGGAT
CAGGTTAACAAATCTATAATTCAATTAAAAAAAGAAATAATTGCTTAGACTAAAGAAAGA
AAGAAGCGCTAGTAATTGTTTGAAGCTAAGAAGGAGGTGTAGGAAGACCTTATTAAAACA
GAGCACTTCAATGTTAAATAAGAGGCATAATCTTAAAATGTAAAATTAGAACATTATTCG
TAACCTATGAATGTGAAATCCGAATATAAAGGAAATGATGCTTTAGCTGAAGATAGTAAT
ATTGAAGAAGAATACAACTACTAGATACTTTGCAATAAATATGAGATGATGGTTTCTTAT
GTATTTTGCTTTATAGATTAGAAAATTAAAACCTTATTCTCAGATTAAGTTTTGGAGATT
TTATAGAAATAGGACAAAGAAAACTTACAAAAAAAATTTGGGCCAGAGGTTGTTTATCTT
CAAAAAAAATCTGACATTAAAGATGAATTGAAATTCAACTACGTATAGATTCGTTTCAAG
CCTTAAACTGCGATGCTTTAAACTGTCTTAAAATAGGAGAATTTGATCAAAAACAAAGCA
GAAAATAATATCACATAAACATCAATTTTCATAGAACACATTTCTTACGACACTAATACC
TACTATTAATTTATACTTTCCTAAGAGAAAATTAATTTTTATCGTTAAATTAGAGCTAAA
TCTCATTAAGAGCAAAAGGAAATTATTGAAAAAATACAATATTATAAACCAAGCCAATTA
ATTAAGGAAAAAATTAACTATAAGAATTTAATTATTTAAGAAGCTATCAAAAATGATTTG
CTTCCTAAATAAAGTTTCTCTTTAACACCGTTCGATACTATTTACATTAAATCTAATATT
ACCCTCAGCTAAATTGACTCTACTCTACTGAGGCCTTTCATAAATTTGGAGGACTAAAAT
TAAATTTAGGTGGATTCTTTATTTTTAATTCATAAACCCAAAGAATTAATAATTTAACCA
GAAAATGTAGATAATCCTTCAAACTCTGATAACGTGAGTTATTTAAGAGTTGTGATAGGA
GATAAAATAGATTTAGAAATTATACTCTAGTAGTACAGAGTAATCATGCTTTAGCAATTT
TTTATTTCAAACTATAAGCTAAGCTAGAGTCTGCATGATGAAAATTCAATGCATTTAGAA
GTTTATGATGAATAGTAAGCTAGCAACATGGTTTTACTAATTAGACAAAAAAGATAGTTA
TATGATGAGGACATTAAATAAATTAGTATAAACAAAATATAAAGCAAGTATTTAACCCAA
GCTGTATTTTAGCTTTAAAATCATCCTCTAATAAAAAACATAATCTACTAGGTCTTGATT
TGTGTTAGGATAACCTGTGATGACCTAGACAGTAAAGACGATAAGGAGATATACTAAATA
ATAATACCATATCTGACAGATAAGCAGCACTACATAATTTATAATAGTTTAAACGAAGAT
ATTATTGAATTAGATTCATAAAAGGAGCAAGAATTAGATGAATTGATATAGGATTTGCAA
AGAAAAGAGCATATTATTTAGAATTTTGTAAACACTGTTTATATAGCACAAGCTGTTTAA
AAAAATATTTTGCACTCCTAATTTAGAGCAATAAGTTAGGAATAAAACAGCGACTACAGT
TAAATTACTATTGAGTGTAGATTAAAAGATGAGTTAAATTCAGATAAGCCAATTAAAATT
TACATATAAAAAAACTTTCATATAAATTTGGAATATAACTTTGGTGAATTGAGAAACTAA
TGCAAAACAGAGGAAATACCGAGAAACTAAAGTTTATCTAGCTTCTACAAACAATTCACT
TTTAATTTAGATTTAAATATCTAAAAATCATTGAAAGATATATATTCCAGGTATAATTAC
TTGAGTGATGATAGAACAAGGATTATAAAAGAATTCCTCAAATTGAAAATTTCAAATGAT
GAATGGTTTACTCAACACAATTTGAAAACTAGACCTGAAACTATTGTACATCACCCTAAT
TAGCAACACACAGGAAGTAATTAAGGTATATAACAAGGAATTAACGGTTAATAGAATGGT
TTAAATCATTATAATCAATAAAGGCCAAATTAAAACCAATTCTAAAATAATTCTATATAG
TAATAAAATAACTCTTAGGGTTTACCAGCAAATCAGTAAGTAGTGGGTTAAGGAAATCAT
TAATAATCTGGAAATCAATAACGCCCATATGCTTAGAATTCTAATTTTAATCAATAATAA
TAACCCTAATAGTCATAACCTGGGACATAAGTTTAATAAAATGGAGCTATGAATAATAGT
TATGGTTAGCAAACAGGATAATCTACCTAAAGAAATCCTTAACAGTATTACTAAAATTAA
TAATAGTATGGAAATAATAATTACAATAATTAAGCATAATAGCAATAAAATCCTAACTAA
TAAGGTGTTGGCTAGTAATCTGGTGCAAATAATTATGCTCACATGAATGGAGCTTAGAAC
TCTTCGTATAACTAGTAATAATATTAAAATTACCAACCAAATAGTAACAGACCTAATTGA
AATGAATGCGGAAAATATGAGAAATAAAATATGAATTTTGAAAGATAGCAATTAATAATT
TTTTAAAATGTGAAAAGATTTATATAACTATTTTAATTAAATAAATAATAAAATTACTTA
TTTAATTTTATATCTATCTATCTGTTAATAATTTATTTTTTAAATAAATACCAAATTGCA
TCAAATCAA

>TTHERM_00052180(protein)
MDKIEYSLYKVCSKIIAHTQNELPTQQNVHDNTQAKDLCDSVMLKFNEFDQLFDRLTNIV
QYLQYDQPEEKKMIDIERQIQEHQNEIWNCGENLNKLHHEFINSPWVNMESVNLMYGRNG
QVKMELLDGYNLGMDYKTKQQEKKHLMRKKLLSMKKPPKVDKIKLKDDRCIVKTDIYQIN
YDLIYDQETDTFNWKIPRTKDIQISDNGLSYLQNFLKDEKSKKDIQTALDQVNKSIIQLK
KEIIAQTKERKKRQQLFEAKKEVQEDLIKTEHFNVKQEAQSQNVKLEHYSQPMNVKSEYK
GNDALAEDSNIEEEYNYQILCNKYEMMVSYVFCFIDQKIKTLFSDQVLEILQKQDKENLQ
KKFGPEVVYLQKKSDIKDELKFNYVQIRFKPQTAMLQTVLKQENLIKNKAENNITQTSIF
IEHISYDTNTYYQFILSQEKINFYRQIRAKSHQEQKEIIEKIQYYKPSQLIKEKINYKNL
IIQEAIKNDLLPKQSFSLTPFDTIYIKSNITLSQIDSTLLRPFINLEDQNQIQVDSLFLI
HKPKELIIQPENVDNPSNSDNVSYLRVVIGDKIDLEIILQQYRVIMLQQFFISNYKLSQS
LHDENSMHLEVYDEQQASNMVLLIRQKRQLYDEDIKQISINKIQSKYLTQAVFQLQNHPL
IKNIIYQVLICVRITCDDLDSKDDKEIYQIIIPYLTDKQHYIIYNSLNEDIIELDSQKEQ
ELDELIQDLQRKEHIIQNFVNTVYIAQAVQKNILHSQFRAISQEQNSDYSQITIECRLKD
ELNSDKPIKIYIQKNFHINLEYNFGELRNQCKTEEIPRNQSLSSFYKQFTFNLDLNIQKS
LKDIYSRYNYLSDDRTRIIKEFLKLKISNDEWFTQHNLKTRPETIVHHPNQQHTGSNQGI
QQGINGQQNGLNHYNQQRPNQNQFQNNSIQQQNNSQGLPANQQVVGQGNHQQSGNQQRPY
AQNSNFNQQQQPQQSQPGTQVQQNGAMNNSYGQQTGQSTQRNPQQYYQNQQQYGNNNYNN
QAQQQQNPNQQGVGQQSGANNYAHMNGAQNSSYNQQQYQNYQPNSNRPN