Identifiers and Description

Gene Model Identifier

TTHERM_00052190

Standard Name

CTH1 (CaTHepsin 1 (Cathepsin D))

Aliases

PreTt11399 | 3.m01858 | 3824.m03154

Description

CTH1 eukaryotic aspartyl protease

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• aspartic-type endopeptidase activity (IEA) | GO:0004190

Biological Process

• proteolysis (IEA) | GO:0006508

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_01548.1	9.997093137033517e-262
	Description: eukaryotic aspartyl protease (460 aa)
DictyBase	DDB_G0279411	9.996696112986116e-50
	Description: ctsD on chromosome: 3 position 2104523 to 2105867
WormBase	WBGene00000217	3.998777993244535e-41
	Description: locus:asp-4 status:Confirmed UniProt:Q21966 protein_id:CAA90633.1
WormBase	WBGene00018777	3.998777993244535e-41
	Description: status:Confirmed UniProt:O45074 protein_id:CCD71735.1
Oxytricha	Contig18588.0.g110	1.999002769139511e-37
	Description: Eukaryotic aspartyl protease
SGD	YPL154C	9.997975313387782e-28
	Description: PEP4 Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates
Stentor Coeruleus	SteCoe_11715	2.3802664086944007e-26
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00052190(coding)
ATGATTAAGTTCAAGAATAAATTAAACTTTGTATTGATTGGTTTGATTCTCATTTTTTAT
TTGATTGGAATTGTAGAATCAAAAAATAACAATGGGAAGCATAAAACTCAAAAATCTTTC
ATTTAGTAGAAGAATGTCTTAAAAAAAAAAATTTACTCAATTCCTTTAACTAAAAAGCTT
CCCTCATAAGAATATCAAATCGAGACTCTAAATATTTTGAAAGAGCATCAAGCTTTACTT
TTGTAAATGAAAACATTTTCTTATTTAGAAATGGATTCTAATAAGCAAATAGTAAAAAAA
TAAAAGCAATTCAACAGTTTTTTGCAAACAGATTTGAAAATGCTAAAATAAAAGCAATCT
TTAGAGCTTAGAAATAGAGATAATTCTTTTTTTACTGGAAGAATAGAAGTAGGAAAATAG
CCTTTTGATGTTATTTTCGATACTGGAAGTGCTTTTGTTTTTATAAATAGCGACTATTGT
GCAGAATGCATGCAAGATCATCACTATTACACTGAAACAAAAACTTTGGAAGAAACTAAT
TTAGACATCACTGTTTAATTTGGTACTGGTTAGTTATCAGGTCTTTTAAGCAAAGATATA
ATAAGTCTAGGAGAAATAGAATTAGAAAAAGGTGTTTTCGCATAGATTACTTAGCAAGAT
GGAAGCTTATTTAAATCTCATTTTGATGGTATTGTTGGTTTATCTGCCCTAGATTTATCT
GAAGAATCCCCTTCTTTACTATCATAATTAAATAATTCTGGACAACTAGAACATAATGTA
GTTTCATTCTTCTTAGAAAGAGACGAAACTGGTTCTTAAATAATTCTAGGAGGAGTAGAC
AAAGACAAATATGATGGTGAAATTTAGTACCATCCAAGAATTGATGAGACTAATTTTTGG
ACTCTCCCTTGCAAATAAATTAAGGTTGGTAATGAGGATACAGGTTTATGCTCTGAAAGC
AACATTTGCAGATTAATTGTAGACTCTGGTACTTCTTTGTTCACTGGTCCTCATGATTCA
GTTGCAGTTCTCTTGAATAAGTTAAATAAAAATGAAGAAGGTTGTAAAAATTTGTATGAT
TTGCCTACAATTACCTTTGTTGTTGAAGACTCTGAATACACAGTTTATCCTAATGAATAC
ATAATAACTTCTACAATCACCCATAGCGATCCTTTTTATGAGCATTCAGATATTGATATA
ATAGTTGAGTGCATGGTTTCATTTTATGGGCTTTAAGTTAATGATCAAGGAGAAAGTTAA
AATACTTGGATTCTTGGAGATGTTTTTATGGGTAAATATTATACTGTTTTTGATAGTGAA
AATAAAAGAATAGGATTAGCTAAATCTATAAACTATGCATCTTATATTCACTGA

>TTHERM_00052190(gene)
ATGATTAAGTTCAAGAATAAATTAAACTTTGTATTGATTGGTTTGATTCTCATTTTTTAT
TTGATTGGAATTGTAGAATCAAAAAATAACAATGGGAAGCATAAAACTCAAAAATCTTTC
ATTTAGTAGAAGAATGTCTTAAAAAAAAAAATTTACTCAATTCCTTTAACTAAAAAGCTT
CCCTCATAAGAATATCAAATCGAGACTCTAAATATTTTGAAAGAGCATCAAGCTTTACTT
TTGTAAATGAAAACATTTTCTTATTTAGAAATGGATTCTAATAAGCAAATAGTAAAAAAA
TAAAAGCAATTCAACAGTTTTTTGCAAACAGATTTGAAAATGCTAAAATAAAAGCAATCT
TTAGAGCTTAGAAATAGAGATAATTCTTTTTTTACTGGAAGAATAGAAGTAGGAAAATAG
CCTTTTGATGTTATTTTCGATACTGGAAGTGCTTTTGTTTTTATAAATAGCGACTATTGT
GCAGAATGCATGCAAGATCATCACTATTACACTGAAACAAAAACTTTGGAAGAAACTAAT
TTAGACATCACTGTTTAATTTGGTACTGGTTAGTTATCAGGTCTTTTAAGCAAAGATATA
ATAAGTCTAGGAGAAATAGAATTAGAAAAAGGTGTTTTCGCATAGATTACTTAGCAAGAT
GGAAGCTTATTTAAAGTAATACTTTAAAGTTTCAATACTAAATTTATGAATATTCAATTA
TTAAATATATTCAAAATATTTAGTTTTGTAATAAATTTTAAAAATATATAATTAGTCTCA
TTTTGATGGTATTGTTGGTTTATCTGCCCTAGATTTATCTGAAGAATCCCCTTCTTTACT
ATCATAATTAAATAATTCTGGACAACTAGAACATAATGTAGTTTCATTCTTCTTAGAAAG
AGACGAAACTGGTTCTTAAATAATTCTAGGAGGAGTAGACAAAGACAAATATGATGGTGA
AATTTAGTACCATCCAAGAATTGATGAGACTAATTTTTGGACTCTCCCTTGCAAATAAAT
TAAGGTTGGTAATGAGGATACAGGTTTATGCTCTGAAAGCAACATTTGCAGATTAATTGT
AGACTCTGGTACTTCTTTGTTCACTGGTCCTCATGATTCAGTTGCAGTTCTCTTGAGTAA
ATAAATTAATATATTTCTTTCTTTCTTATATTTATAATATTTTAATTTAGATAAGTTAAA
TAAAAATGAAGAAGGTTGTAAAAATTTGTATGATTTGCCTACAATTACGTAAACAATAAA
AATCAATTAAAATATTTAAATTAACCTCATTTTATGAAAAAAGCTTTGTTGTTGAAGACT
CTGAATACACAGTTTATCCTAATGAATACATAATAACTTCTACAATCACCCATAGCGATC
CTTTTTATGAGCATTCAGATATTGATATAATAGTTGAGTGCATGGTTTCATTTTATGGGC
TTTAAGTTAATGATCAAGGAGGTAATTATTTCATTTATTCTTTAAAAATTTTAAAATAAA
AACTAATTATTTATTAAATTAATTTCAATTTTTATTCTCTATTCTAATTTAGAAAGTTAA
AATACTTGGATTCTTGGAGATGTTTTTATGGGTAAATATTATACTGTTTTTGATAGTGAA
AATAAAAGAATAGGATTAGCTAAATCTATAAACTATGCATCTTATATTCACTGA

>TTHERM_00052190(protein)
MIKFKNKLNFVLIGLILIFYLIGIVESKNNNGKHKTQKSFIQQKNVLKKKIYSIPLTKKL
PSQEYQIETLNILKEHQALLLQMKTFSYLEMDSNKQIVKKQKQFNSFLQTDLKMLKQKQS
LELRNRDNSFFTGRIEVGKQPFDVIFDTGSAFVFINSDYCAECMQDHHYYTETKTLEETN
LDITVQFGTGQLSGLLSKDIISLGEIELEKGVFAQITQQDGSLFKSHFDGIVGLSALDLS
EESPSLLSQLNNSGQLEHNVVSFFLERDETGSQIILGGVDKDKYDGEIQYHPRIDETNFW
TLPCKQIKVGNEDTGLCSESNICRLIVDSGTSLFTGPHDSVAVLLNKLNKNEEGCKNLYD
LPTITFVVEDSEYTVYPNEYIITSTITHSDPFYEHSDIDIIVECMVSFYGLQVNDQGESQ
NTWILGDVFMGKYYTVFDSENKRIGLAKSINYASYIH