Identifiers and Description

Gene Model Identifier

TTHERM_00068140

Standard Name

LSC1 (Ligase of Succinyl-CoA  )

Aliases

PreTt13203 | 4.m00602 | 3707.m00239

Description

LSC1 succinyl-CoA synthetase alpha subunit; Alpha subunit of succinyl-CoA ligase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• catalytic activity (IEA) | GO:0003824

Biological Process

• metabolic process (IEA) | GO:0008152

Domains

• ( PF00549 ) CoA-ligase
• ( PF01113 ) Dihydrodipicolinate reductase, N-terminus
• ( PF01408 ) Oxidoreductase family, NAD-binding Rossmann fold
• ( PF02629 ) CoA binding domain
• ( TIGR01019 ) succinate-CoA ligase, alpha subunit
• ( TIGR02717 ) acetyl coenzyme A synthetase (ADP

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_02112.1	9.997093137033517e-262
	Description: succinyl-CoA synthetase, alpha subunit protein (311 aa)
DictyBase	DDB_G0289325	7.998494937295598e-144
	Description: scsA on chromosome: 5 position 2650999 to 2652299
Oxytricha	Contig13094.0.g105	5.000301007691871e-141
	Description: CoA binding domain
WormBase	WBGene00007350	5.997858334163121e-134
	Description: locus:sucl-1 Probable succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial status:Confirmed UniProt:P53596 protein_id:CAA94107.1
WormBase	WBGene00002189	5.997858334163121e-134
	Description: locus:kin-1 cAMP-dependent protein kinase catalytic subunit status:Confirmed UniProt:P21137 protein_id:CAD45618.1
SGD	YOR142W	6.999054974866289e-109
	Description: LSC1 Alpha subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate; phosphorylated
Stentor Coeruleus	SteCoe_35214	1.7785284761271306e-68
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00068140(coding)
ATGTTGTCAAAGACTATTTCCAATTTCTTCAGCTCTACCAAGCCCTACGTTTGGATTAAC
AAGCACACTAAGGTTATTTGCCAAGGTATCACTGGTAACCAAGGTACTTTACACACTCAA
CAAGCTCTTGAATACGGTACTAAGATGGTTGGTGGTGTCAATCCTGCTAAGGCTGGTCAA
ACCCACTTGGGCTTACCCGTTTTCAAGAACTGCCAAGAAGCCAAGAAAGTCACCGGTTGT
GATGCTTCCGTTATCTACGTTCCTCCCCCTCATGCTGCTAAGGCTATTATGGAAGCTATT
GAAGCTGAAATTCCCTTGGTCGTTGTCATCACCGATGGTATCCCATAACACGACATGGTC
AAGGTTAAGCACGCTCTTAGACAACAAAAGATTACCAGAATTATTGGTCCCAATTGCCCT
GGTATCATTAAGCCCAACGAATGTAAGATTGGTATTATGCCCGGTTACATTCACAAGCCT
GGTAAAATCGGTATCGTCTCAAGATCTGGTACTTTGACTTACGAAGCTGTTGACTAAACT
ACTAAGGCTGGTTTGGGTCAATCTACCGTCGTTGGTATTGGTGGTGATCCTTTCAACGGT
ACCAATTTCATCGATGTCCTCGAAAGATTCGTTGAAGATCCCGAAACTGAAGGTATTTTA
TTAATTGGTGAAATCGGTGGTGAAGCTGAAGAACAAGCTGCTGCCTGGTTGAAGGCTAAC
AATAAAACCAACAAGCCCGTTGTTTCTTTCATTGCTGGTGTTACTGCTCCTCCTGAGAGA
AGAATGGGTCACGCTGGTGCTATCGTTTCTGGTGGTAAGGGTTCTGCCACTGAAAAGATC
AAGGCTTTAGAATCTGCTGGCATTAAGGTCTGCAGATCTCCTGCCACCTTAGGTCAAGAA
ATGCTCAACCTCATGAAGGTCCATAAGAACTGA

>TTHERM_00068140(gene)
ATGTTGTCAAAGACTATTTCCAATTTCTTCAGCTCTACCAAGCCCTACGTTTGGATTAAC
AAGCACACTAAGGTTATTTGCCAAGGTATCACTGGTAACCAAGTAAGAATTGATATCAAT
TTCTAAATTTTGAGCTATTTTCATTTGTTCTCCAGCTCGCTTTTGGATTTTAGCAAATGC
TCTCCCTTTCCTTCATTTTCTCTATTAGTCATTTTAAACCATATCCTCTTCAAATGAAAA
TATTTCTTCAGTTTGAAAGTTTCAAAGCAAATAGACCTTAAAAAGTAAAATAGCCATGAA
AATAAAAATGATTATCAAGTATCAAAAAATACAAATTAAGCAGTCAAATTGTAAAAAATC
GAAGCAAATAAATAAAGTCCAATTCAAATTTCAGCAAAAGAGCATTAAAATCGTAGATAA
GGGAGTATTAAAACACAGAAATTATTTGAATTATTACTGCAAAACAAAATTCAGTCAAAT
CCAAAACAAGCTACATATTAGAAGAAATCTCTTTTATAAATCTCATTTGAATAAGCAAAA
AAAGAACTTTAAAAAGAAGGGAATCAACAATCGTATTTCCAAGGAAACAGATATATCTAT
CTTATTTATTCATTTGAAGCGAGAGAATAAATTAGAAAAATTTAGAGATATTTATTTATT
AAAACTCCTTTTATTAAAATTTAGGGTACTTTACACACTCAACAAGCTCTTGAATACGGT
ACTAAGATGGTTGGTGGTGTCAATCCTGCTAAGGCTGGTCAAACCCACTTGGGCTTACCC
GTTTTCAAGAACTGCCAAGAAGCCAAGAAAGTCACCGGTTGTGATGCTTCCGTTATCTAC
GTTCCTCCCCCTCATGCTGCTAAGGCTATTATGGAAGCTATTGAAGCTGAAATTCCCTTG
GTCGTTGTCATCACCGATGGTATCCCATAACACGACATGGTCAAGGTTAAGCACGCTCTT
AGACAACAAAAGATTACCAGAATTATTGGTCCCAATTGCCCTGGTATCATTAAGCCCAAC
GAATGTAAGATTGGTATTATGCCCGGTTACATTCACAAGCCTGGTAAAATCGGTAAGCAA
ATTACTCTTAAATATTCACTCAAGCTATATTTTTAATTACCTTTCAGTTTGCACTTTGAT
TCTAAAAAAGAGAATGCTTAAGAAGTTTCGCATATTAATAGCTAACTGCATTTTTAATAA
TTCAAAATAATCTGAATATTCTGCCTTAATTTTATTAAATTAATTGAAGGAAAGAACTTA
AATAGATTAAATTGCTTAATAAAAAGTATCTTAAAAAAGACTATATCGTTTTTCTTTTTT
ACTTAAGATGTGTAGAAAACAATAGAACTATTTATATCTTTAAAAGAATACAAAAGAACA
TTATTTTTTAGACAAAAATTCAAAATAAAATAATAATAACAAATTAAATTAATAGATAAA
TAAATATACAAAAAACATCAAGCATATCTTAAATTTATTTATTTATTTTGTAGATAAGGT
GCAGATTGAAATAATTAAAATGAATGATTAAATTTAGTTTCTTCCTTACATAATTCTTAT
ATTTTATATAAAAGGTATCGTCTCAAGATCTGGTACTTTGACTTACGAAGCTGTTGACTA
AACTACTAAGGCTGGTTTGGGTCAATCTACCGTCGTTGGTATTGGTGGTGATCCTTTCAA
CGGTACCAATTTCATCGATGTCCTCGAAAGATTCGTTGAAGATCCCGAAACTGAAGGTAA
AAAAAAATAATAAAATTATATTAATTCAGCTTATTAAAAGATAGCATTATTATTTGGCAA
TAAGATTTAGAATATAGCAAAATTATAGAATATATAATGCTTTTAAAATAAATAATATTG
ATTAAACATATTATTTGTAAATTTACTTAAGAAATACTTTCTTAATAAAATGCTAAAAGA
TTTTACTAATTTTAGATTATTTATTTAAAAATTGTAATTAATTTTGAAAACTTGCTCACT
AATTGTTTTATAAAAAAAGGTATTTTATTAATTGGTGAAATCGGTGGTGAAGCTGAAGAA
CAAGCTGCTGCCTGGTTGAAGGCTAACAATAAAACCAACAAGCCCGTTGTTTCTTTCATT
GCTGGTGTTACTGCTCCTCCTGAGAGAAGAATGGGTCACGCTGGTGCTATCGTTTCTGGT
GGTAAGGGTTCTGCCACTGAAAAGATCAAGGCTTTAGAATCTGCTGGCATTAAGGTCTGC
AGATCTCCTGCCACCTTAGGTCAAGAAATGCTCAACCTCATGAAGGTCCATAAGAACTGA

>TTHERM_00068140(protein)
MLSKTISNFFSSTKPYVWINKHTKVICQGITGNQGTLHTQQALEYGTKMVGGVNPAKAGQ
THLGLPVFKNCQEAKKVTGCDASVIYVPPPHAAKAIMEAIEAEIPLVVVITDGIPQHDMV
KVKHALRQQKITRIIGPNCPGIIKPNECKIGIMPGYIHKPGKIGIVSRSGTLTYEAVDQT
TKAGLGQSTVVGIGGDPFNGTNFIDVLERFVEDPETEGILLIGEIGGEAEEQAAAWLKAN
NKTNKPVVSFIAGVTAPPERRMGHAGAIVSGGKGSATEKIKALESAGIKVCRSPATLGQE
MLNLMKVHKN