Identifiers and Description
Gene Model Identifier
TTHERM_00068170Standard Name
TCB2 (Tetrahymena Calcium-Binding 2 )Aliases
TCBP-25 | 4.m00605 | PreTt13206 | 3707.m00242Description
TCB2 25 kDa calcium-binding protein; 25 kD Ca(2+)-binding protein containing four EF-hand loops; localized to cell cortex except in and around basal bodies- and around both the migratory and stationary gametic pronuclei during pronuclear exchange stage of conjugationGenome Browser (Macronucleus)
Genome Browser (Micronucleus)
External Links
Gene Ontology Annotations
Cellular Component
- cortical cytoskeleton (IDA) | GO:0030863
- pronucleus (IDA) | GO:0045120
Molecular Function
- calcium ion binding (IDA) | GO:0005509
Domains
Gene Expression Profile
Vegetative Cell Cycle (Zhang et al., 2023)
GeneMania
Tetrahymena Stock Center
No Data fetched for Tetrahymena Stock Center
Homologs
Source Identifier Score Tetrahymena borealis EI9_02114.1 1.0003491030231826e-151 Description: EF hand family protein (219 aa) Oxytricha Contig13881.0.g74 0.0000020007268868677913 Description: EF-hand domain pair DictyBase DDB_G0287009 0.00003998524687536623 Description: mcfC on chromosome: 4 position 5197882 to 5199603 WormBase WBGene00006861 0.00010003404299092957 Description: locus:cal-5 status:Confirmed UniProt:Q18136 protein_id:CCD65556.1
General Information
No Data fetched for General Information
Associated Literature
- Ref:10503211: Numata O, Hanyu K, Takeda T, Watanabe Y (2000) Tetrahymena calcium-binding proteins, TCBP-25 and TCBP-23. Methods in cell biology 62( ):455-65
- Ref:7641801: Hanyu K, Takemasa T, Numata O, Takahashi M, Watanabe Y (1995) Immunofluorescence localization of a 25-kDa Tetrahymena EF-hand Ca(2+)-binding protein, TCBP-25, in the cell cortex and possible involvement in conjugation. Experimental cell research 219(2):487-93
- Ref:1880125: Kimura M, Hirono M, Takemasa T, Watanabe Y (1991) Drastic change in the level of actin mRNA in the course of synchronous division in Tetrahymena. Journal of biochemistry 109(3):399-403
- Ref:2303413: Takemasa T, Takagi T, Kobayashi T, Konishi K, Watanabe Y (1990) The third calmodulin family protein in Tetrahymena. Cloning of the cDNA for Tetrahymena calcium-binding protein of 23 kDa (TCBP-23). The Journal of biological chemistry 265(5):2514-7
- Ref:2808424: Takemasa T, Ohnishi K, Kobayashi T, Takagi T, Konishi K, Watanabe Y (1989) Cloning and sequencing of the gene for Tetrahymena calcium-binding 25-kDa protein (TCBP-25). The Journal of biological chemistry 264(32):19293-301
Sequences
>TTHERM_00068170(coding)
ATGAAATAAATAAATAAAAACTTTAAATAGATATGCGTGATTGCTTTAATAATTTAATTT
AATAAATTACGAATTATCTTCTTTTTATTACTTGTTTATTTTCAAGTATCTCATTCAGAA
CGATTTAAATAAAAACTTAAATAAAAAATTATTTATAATCTTTAAAGCAAAAAAAAATTA
ATTAAATAAAATTCAAAAAACAACAAACAAACAATAAATAAATAAATGGCTCAATACTCT
CAAACTCTCAGATCTTCTGGTTTCACTTCCACTGTTGGTCTCACCGATATTGAAGGTGCT
AAGACTGTCGCTAGAAGAATCTTCGAAAACTACGACAAGGGCAGAAAGGGCAGAATCGAA
AACACCGACTGTGTTCCCATGATTACTGAAGCCTACAAGTCCTTCAACTCCTTCTTTGCC
CCCTCTTCTGATGACATCAAGGCCTACCACAGAGTCCTCGACAGAAACGGTGACGGTATT
GTTACTTACTAAGATATTGAAGAACTTTGCATCAGATACCTCACTGGTACCACTGTCTAA
AGAACTATCGTCACTGAAGAAAAGGTTAAGAAGTCCAGCAAGCCCAAATACAACCCTGAA
GTTGAAGCTAAGCTCGACGTCGCTAGAAGACTCTTCAAGAGATACGACAAGGACGGTTCT
GGTTAATTACAAGATGACGAAATCGCTGGCTTATTAAAGGACACCTATGCTGAAATGGGT
ATGTCCAACTTCACCCCTACTAAGGAAGACGTTAAGATCTGGTTATAAATGGCTGACACC
AACTCTGATGGTTCAGTCTCCCTTGAAGAATACGAAGACCTCATTATCAAGTCTCTCCAA
AAGGCTGGTATTAGAGTCGAAAAGTAATCCTTAGTTTTCTGA>TTHERM_00068170(gene)
ATGAAATAAATAAATAAAAACTTTAAATAGATATGCGTGATTGCTTTAATAATTTAATTT
AATAAATTACGAATTATCTTCTTTTTATTACTTGTTTATTTTCAAGTATCTCATTCAGAA
CGATTTAAATAAAAACTTAAATAAAAAATTATTTATAATCTTTAAAGCAAAAAAAAATTA
ATTAAATAAAATTCAAAAAACAACAAACAAACAATAAATAAATAAATGGCTCAATACTCT
CAAACTCTCAGATCTTCTGGTTTCACTTCCACTGTTGGTCTCACCGATATTGAAGTAAAT
ACTCCCACCATTCAAAACAATTATATCCCTTAGCCTACAGTCTTTCAGGTTATTAACTCT
CACTAATATCATCTACCACACATCGATATCAATCATCACGAACTGATGCTGATTTTACTT
GAGCCAGTGAAAAGAAATTTGATGGTTTTGTAAAAGGAAGCAAATAGAGCATGTTATAGA
GTAAAAGAATATAAATAAAGAAGTAAGTTATCAACCATATTTACTAGAATGAATAAAACG
AAATGGTATTTAGCCTTTAAAAGATAGCAAAAAAATTTTGAAGATACACTTTAAAAAGCT
TGGTACCATATAAAATAAATCAAGTCAGCAAGTATAAATACAAGCAAAAATTAACAAAAA
ATAAATAAATAAACTTACTTCTTCTTTTTATGATAACTCTTGATTCTTATCTAGCATCAA
AACAATATGAAATCAATTTACTTAAGAAGCAGAGGCTCTAGATACAGATCAGATATGAAC
AAAAGCGGTATTGAGTTAGCTAGTTGATGAGTTAGTGATCAAAAGACTTTGGCTATAATT
ATTTGACAAACATTTTTTCTTATAATCTAATTAATCTTTTCTAATAGGGTGCTAAGACTG
TCGCTAGAAGAATCTTCGAAAACTACGACAAGGGCAGAAAGGGCAGAATCGAAAACACCG
ACTGTGTTCCCATGATTACTGAAGCCTACAAGTCCTTCAACTCCTTCTTTGCCCCCTCTT
CTGATGACATCAAGGCCTACCACAGAGTCCTCGACAGAAACGGTGACGGTATTGTTACTT
ACTAAGATATTGAAGAACTTTGCATCAGATACCTCACTGGTACCACTGTCTAAAGAACTA
TCGTCACTGAAGAAAAGGTTAAGAAGTCCAGCAAGCCCAAATACAACCCTGAAGTTGAAG
CTAAGCTCGACGTCGTAAGAAATAAATACATTTTATTCTTTTTTAGAACTTATAAAAAAT
TTTAAAACGTAATTTTAAAATATCTTTTTAAATTAAAATAGGCTAGAAGACTCTTCAAGA
GATACGACAAGGACGGTTCTGGTTAATTACAAGATGACGAAATCGCTGGCTTATTAAAGG
ACACCTATGCTGAAATGGGTATGTCCAACTTCACCCCTACTAAGGAAGACGTTAAGATCT
GGTTATAAATGGCTGACACCAACTCTGATGGTTCAGTCTCCCTTGAAGAATACGAAGACC
TCATTATCAAGTCTCTCCAAAAGGCTGGTATTAGAGTCGAAAAGTAATCCTTAGTTTTCT
GA>TTHERM_00068170(protein)
MKQINKNFKQICVIALIIQFNKLRIIFFLLLVYFQVSHSERFKQKLKQKIIYNLQSKKKL
IKQNSKNNKQTINKQMAQYSQTLRSSGFTSTVGLTDIEGAKTVARRIFENYDKGRKGRIE
NTDCVPMITEAYKSFNSFFAPSSDDIKAYHRVLDRNGDGIVTYQDIEELCIRYLTGTTVQ
RTIVTEEKVKKSSKPKYNPEVEAKLDVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMG
MSNFTPTKEDVKIWLQMADTNSDGSVSLEEYEDLIIKSLQKAGIRVEKQSLVF