Identifiers and Description

Gene Model Identifier

TTHERM_00079000

Standard Name

IMA4 (IMportin Alpha 4)

Aliases

PreTt10146 | 5.m00497 | 3828.m01409

Description

IMA4 importin subunit alpha putative; Armadillo/beta-catenin-like repeat family protein; Karyopherin/Importin alpha family member

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• micronucleus (EXP) | GO:0031040

Biological Process

• regulation of protein import into nucleus (IDA) | GO:0042306

Domains

• ( PF00514 ) Armadillo/beta-catenin-like repeat
• ( PF05316 ) Mitochondrial ribosomal protein (VAR1)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_07035.1	9.997093137033517e-262
	Description: hypothetical protein (517 aa)
WormBase	WBGene00009201	9.997093137033517e-262
	Description: status:Partially_confirmed UniProt:H2L2C5 protein_id:CCE72265.1
Oxytricha	Contig20249.0.g40	6.000675497867615e-22
	Description: Armadillo/beta-catenin-like repeat
DictyBase	DDB_G0272318	7.000255027549774e-17
	Description: DDB_G0272318 on chromosome: 2 position 1278811 to 1280712
SGD	YNL189W	0.000000000000005001692698841201
	Description: SRP1 Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation
WormBase	WBGene00002074	0.0000000010002658722841845
	Description: locus:ima-3 Importin subunit alpha-3 status:Confirmed UniProt:Q19969 protein_id:CCD70435.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:18676955: Malone CD, Falkowska KA, Li AY, Galanti SE, Kanuru RC, LaMont EG, Mazzarella KC, Micev AJ, Osman MM, Piotrowski NK, Suszko JW, Timm AC, Xu MM, Liu L, Chalker DL (2008) Nucleus-specific importin alpha proteins and nucleoporins regulate protein import and nuclear division in the binucleate Tetrahymena thermophila. Eukaryotic cell 7(9):1487-99

Sequences

>TTHERM_00079000(coding)
ATGACAACTTTGGAAAATCCTACTAGCTCTATTATTAACAGCAATATCAACCCAAATTCT
ATTTTTGGTAGTACTTCTCTTTCGAAGGAAGAAAATGATGATGTTAGAAAGATGATTTCT
TATAAAAAGGAAGACTTTCGTGAAGATATAAGGAAATCAAAAACGAATAGCGCCCTCTAG
TAGAAGCGTATTAGAGTCTTTAAGCAGAATGCTATCTAAAAATGTGAAGAATAATGTCAA
GAGAGTTTGTAAATATTTTACAAGGCAGAAAAAGAATCAAATTTAGAGTAATTGCAACTA
TCTATAAGTAAAATGAAAGAACTCTCTTAAGAATAAAGAAGTTAAAGATATTTGCTAAAC
ACAGATGTAGTTAAGTATCTCTGCGTGTTAGTAGGTCCTGGATTTAGATAATATAATTAG
CTTTAAATAGATGTGTGCTGGATTTTAGCTAATTTATCTTGCGAACCATCTTTTAACCTT
TAAAAATATGAAAACTTGCCAAAGGAGCTTATTCAAAATCTTTTAATGCTTTTAGATGCT
GAAAAGATAGAGTCCATAAATGCAGCTTTTTGGTGTTTAAGTAATTTAGCAGGTGACCCA
AATTATACTTAGATCATATATGAAGCTAATGTGATAGGAAAAATCACAAGCATCCTTGAG
TAGAAGAAATTTAATGAAGAAATTATTTGTTAAATTAGCTACACCTACTTAAATATTACA
GATTAAATTAAAACTATGGATGAAAAAAGCGTGCAATTAATTTTATCAACAATAAATGAA
TTCTCAGATATTAAAAATGATGAAATTATTTTTAATTTGATCAGAATTATCAACAATATT
GCAAAGGAAGAAAAAAATGCTCAGATTCTTAGAACATAATTTAACAGCAAGTTAATGAAT
CTCATTTTTTTGATTTTTGCAACTCACAATCATTACTATTTGGAATCTATTTTAGAGTGT
GTTGGAAATTTAATTCATCTTAATGAATCTTTTGCTAGAGTTATTTTAGAGAAAGGATTT
AATTAAAGTTTAGTAATTTGCTTAGAAACTAAAGAAAAAAGTATTAGAAAGAGAGCAGGA
TGGGTGATTAGCAATATTCTCTCATGCAGCCAATAAGATATCGACGAAATATTTAATTAC
AGTGCTTTATTAAATAAAATCCTTACTTTGATAGTTATTGATACTTTAGAAGTAAAAAGC
GTTCTTTTACAAGGCTTATTTAATGCTCTAGAAAAGGCAACAAAAGAACAAATATCAAAT
CTTATTAAAAAAGATTTTATATAAGTTTTGTATAATGTTTTAAAAGAAGAAAACAATGAA
TATCTAATTATAAAGTGCATAGATATTCTCAATATTTTATTAACTTTTGATAGAGAAAAC
TAATTAGATGGAGAATAACAAGAAAGTCTGGTCTTCAATTAACTCTCTAACACTGGTCTT
ATTGAAATCATTTAAAACCTTCAAATTCATTCAAGTGATCTTGTTTACAACAAAATAGTT
AAACTTATCAATGATTTCTTTGATTTTGAGGAATCTAGTGAGTGA

>TTHERM_00079000(gene)
ATGACAACTTTGGAAAATCCTACTAGCTCTATTATTAACAGCAATATCAACCCAAATTCT
ATTTTTGGTAGTACTTCTCTTTCGAAGGAAGAAAATGATGATGTTAGAAAGATGATTTCT
TATAAAAAGGAAGACTTTCGTGAAGATATAAGGAAATCAAAAACGAATAGCGCCCTCTAG
TAGAAGCGTATTAGAGTCTTTAAGCAGAATGCTATCTAAAAAGTAAGCTTTCACTGATAT
AAAACTTTTTATTTAGCATTTTGATGTGCTTTTTACCAAAATAAATTAATTTATTAATTA
ATGACTGATTATCTTACTCAATATATATAAGTGAAATAAATTTTTTATTTAAATAGTGTG
AAGAATAATGTCAAGAGAGTTTGTAAATATTTTACAAGGCAGAAAAAGAATCAAATTTAG
AGTAATTGCAACTATCTATAAGTAAAATGAAAGAACTCTCTTAAGAATAAAGAAGTTAAA
GATATTTGCTAAACACAGATGTAGTTAAGTATCTCTGCGTGTTAGTAGGTCCTGGATTTA
GATAATATAATTAGCTTTAAATAGATGTGTGCTGGATTTTAGCTAATTTATCTTGCGAAC
CATCTTTTAACCTTTAAAAATATGAAAACTTGCCAAAGGAGCTTATTCAAAATCTTTTAA
TGCTTTTAGATGCTGAAAAGATAGAGTCCATAAATGCAGTAATTAAATTTTTCAAAATAT
TAATTTTTAGTAAGCTTTAAATTAATATCTTTTTTTTGCGGAAATTAATTAATTAATTAG
GCTTTTTGGTGTTTAAGTAATTTAGCAGGTGACCCAAATTATACTTAGATCATATATGAA
GCTAATGTGATAGGAAAAATCACAAGCATCCTTGAGTAGAAGAAATTTAATGAAGAAATT
ATTTGTTAAATTAGCTACACCTACTTAAATATTACAGATTAAATTAAAACTATGGATGAA
AAAAGCGTAAAAGTTTATTTATTTTTTATATTCATTAAATTAATTAACATTTAAAATTTT
AGGTGCAATTAATTTTATCAACAATAAATGAATTCTCAGATATTAAAAATGATGAAATTA
TTTTTAATTTGATCAGAATTATCAACAATATTGCAAAGGAAGAAAAAAATGCTCAGATTC
TTAGAACATAATTTAACAGCAAGTTAATGAATCTCATTTTTTTGATTTTTGCAACTCACA
ATCATTACTATTTGGAATCTATTTTAGAGTGTGTTGGAAATTTAATTCATCTTAATGAAT
CTTTTGCTAGAGTAACCAATCAATCAAACTAATTTAATGCATAATTATTGAAAATTAATT
TTATTAAAATAGGTTATTTTAGAGAAAGGATTTAATTAAAGTTTAGTAATTTGCTTAGAA
ACTAAAGAAAAAAGTATTAGAAAGAGAGCAGGATGGGTGATTAGCAATATTCTCTCATGC
AGCCAATAAGATATCGACGAAATATTTAATTACAGTGCTTTATTAAATAAAATCCTTACT
TTGATAGTTATTGATACTTTAGAAGTAAAAAGCGTTCTTTTACAAGGCTTATTTAATGCT
CTAGAAAAGGCAACAAAAGAACAAATATCAAATCTTATTAAAAAAGATTTTATATAAGTT
TTGTATAATGTTTTAAAAGAAGAAAACAATGAATATCTAATTATAAAGTGCATAGATATT
CTCAATATTTTATTAACTTTTGATAGAGAAAACTAATTAGATGGAGAATAACAAGAAAGT
CTGGTCTTCAATTAACTCTCTAACACTGGTCTTATTGAAATCATTTAAAACCTTCAAATT
CATTCAAGTGATCTTGTTTACAACAAAATAGTTAAACTTATCAATGATTTCTTTGATTTT
GAGGAATCTAGTGAGTGA

>TTHERM_00079000(protein)
MTTLENPTSSIINSNINPNSIFGSTSLSKEENDDVRKMISYKKEDFREDIRKSKTNSALQ
QKRIRVFKQNAIQKCEEQCQESLQIFYKAEKESNLEQLQLSISKMKELSQEQRSQRYLLN
TDVVKYLCVLVGPGFRQYNQLQIDVCWILANLSCEPSFNLQKYENLPKELIQNLLMLLDA
EKIESINAAFWCLSNLAGDPNYTQIIYEANVIGKITSILEQKKFNEEIICQISYTYLNIT
DQIKTMDEKSVQLILSTINEFSDIKNDEIIFNLIRIINNIAKEEKNAQILRTQFNSKLMN
LIFLIFATHNHYYLESILECVGNLIHLNESFARVILEKGFNQSLVICLETKEKSIRKRAG
WVISNILSCSQQDIDEIFNYSALLNKILTLIVIDTLEVKSVLLQGLFNALEKATKEQISN
LIKKDFIQVLYNVLKEENNEYLIIKCIDILNILLTFDRENQLDGEQQESLVFNQLSNTGL
IEIIQNLQIHSSDLVYNKIVKLINDFFDFEESSE