Identifiers and Description

Gene Model Identifier

TTHERM_00088010

Standard Name

AFA1 (AAA Family ATPase 1)

Aliases

PreTt16451 | 6.m00525 | 3836.m02117 | QUEENB1

Description

AAA family ATPase; ATPase- AAA family protein; localizes to micronucleus during conjugation

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• ciliary tip (IDA) | GO:0097542
• cytoplasm (IDA) | GO:0005737
• cytoplasmic vesicle lumen (IDA) | GO:0060205
• micronucleus (IDA) | GO:0031040
• oral apparatus (IDA) | GO:0031912

Molecular Function

• ATP binding (IEA) | GO:0005524
• ATP hydrolysis activity (IEA) | GO:0016887

Domains

• ( PF00004 ) ATPase family associated with various cellular activities (AAA)
• ( PF00158 ) Sigma-54 interaction domain
• ( PF01078 ) Magnesium chelatase, subunit ChlI
• ( PF07724 ) AAA domain (Cdc48 subfamily)
• ( PF07726 ) ATPase family associated with various cellular activities (AAA)
• ( PF07728 ) AAA domain (dynein-related subfamily)
• ( PF09336 ) Vps4 C terminal oligomerisation domain
• ( TIGR00635 ) Holliday junction DNA helicase RuvB
• ( TIGR01241 ) ATP-dependent metallopeptidase HflB
• ( TIGR01242 ) 26S proteasome subunit P45 family
• ( TIGR02880 ) CbbX protein
• ( TIGR02881 ) stage V sporulation protein K
• ( TIGR03263 ) guanylate kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_02490.1	9.997093137033517e-262
	Description: ATPase, AAA family protein (746 aa)
Oxytricha	Contig1478.1.g58	1.9996385480812013e-123
	Description: ATPase family associated with various cellular activities (AAA)
DictyBase	DDB_G0268334	7.998584418911683e-103
	Description: DDB_G0268334 on chromosome: 1 position 714031 to 716367
WormBase	WBGene00017981	3.0006488705143073e-92
	Description: locus:figl-1 Fidgetin-like protein 1 status:Partially_confirmed UniProt:O16299 protein_id:CCD68481.1
Tetrahymena borealis	EI9_05968.1	3.0006488705143073e-92
	Description: hypothetical protein (532 aa)
SGD	YPL074W	7.998415523157811e-91
	Description: YTA6 Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but not to daughter cells
Stentor Coeruleus	SteCoe_15273	4.1863939993042314e-51
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00088010(coding)
ATGCTTTCTACTTATAAAGATGCTGGGGATGGGGGATTGTAATAAGATAATTTAATTCCA
ATGTAGAAGGAAACCCTTAAGAGTATTTTATCCAGCTTTAAAAATAAGATGAATGAGACT
CATTAATTGTATTCTTAAAATTCAAACTCTCTTCAAAAAGAAGATAAAGAAGATGTATAT
AAACATGCTTTTTCTTTCGCTTTTCTACTTTAAAAGTATTAAGAGAAAGACAACTCACTA
TGTTTAGAAGATTTTATTTAAGAAGCTGAACGAATGAGAGATCATCAGTTATACAAACCA
AGCAAGGCTAATAAAAAGTTTAATATAATGCCAAAAATATCTAAAGAAAAGTTTGAGTAA
TTTATAGAATATGAAAAAGATACAAGATTTCCTCAACCTAGAAAAACAGTACAGTTAAAT
ACTCAAGCAAGACTTCCAGAAAGACAAACATCAAATTAAAAGCCTGCAATAAGTAGTTTA
TTGAATAGCAATAATAATTAAATCTCATCCAACTCTAATTAAGGATATGGGAATATAAAT
AGTTTTTAGAACAATCCTAATAATAGTATTGATAATAATAAAAATAATAATAATAATTTT
GGTCCTACTTAACAAAATAATAACAATGGGTTTTATAGATCTCAAAGCAGTTAAAATTAA
GATGAACAACCATAAAAAACAAATGGATATAAATAATAGTATAACAATGGCTACAACAGC
TATTAAAATTAAAATACAAATAATTTTGGGTATGGTAGAAATAGGTATCAAAATAACAAT
AGATATAATAAAGGAAGGGAGTAAATTGAAGAAGAATAAGATGAGTAATAGTAAGCTGGA
GGTTTTAAAACAGCATCAGAATAAAGATATTAAAATAATATGTTAAAGAGATAAAAAGAA
GAAGGATTCTATAATAAAGAAACTGGAAAATATGGTAGAAATAATGGATAGCTAGAGTTT
GAAGGTGTGAATGATAATAAACCTAAATACGGATATACAAAATATGGAAGTAACTAGGGA
GTTGATGATGTTGTTAATCTTGTCCATTACCATACTATAGGGAAAAACCTCAATTTAAAT
AATAATTCTTCATCTAATTAAGCTGCTGCCTTAAATGGAGGTGGTACAGAAGACGAATAT
AAAAAGACAGGACTAAGCAGAAAATTCAAACCTCCAGGAGCACCTGGTTCAAATACCGGA
GGGAAAAAAAATGAATAGTGTGAGCAGCTCAAAGGAATGGATTAAAAATTAATAGATTTA
ATTGAAAACGAAATTGTAGAAAATGCTGCTAATGTTAAGTGGGAAGATATAGCTGGTTTA
AGTTCAGCTAAGGAATCTGTCAAGGAAACTATAGTTTGGCCTATGTTGAACCCATAAATC
TTTACTGGTATTAGAGCTCCTCCTAAAGGTCTTCTCTTGTTTGGACCACCTGGAACAGGT
AAGACTATGATTGGCAAGGCTATTGCTAATCAATCTGGCTCTACATTTTTTTCTATATCA
GCATCTTCTCTAACAAGTAAATATATTGGTGAAGGTGAGAAAATGGTAAAAATTCTCTTC
AAGCTAGCAGAAATGAGATAACCAAGTGTTATTTTTATTGATGAAATAGACTCACTTTTA
TGTGCAAGATAAGAAAATGAAAATGAGGCAAGTAGAAGAATTAAGACAGAGTTTTTAGTT
TAAATGGAAGGTGCTACTTCAAGAGAAGAAGTAAGATTGTTACTTATAGGAGCAACAAAT
AGGCCATAAGAACTTGATGATGCTGTTAGAAGAAGATTTGTTAAGAAATTATATATTCCT
CTACCTAATATGGTAGCAAGAGAGTAATTGATAAGAAGAGTAATTGAAAGAGAATCAGCA
AAAGGAAACGCTTTTGATATGAGCGACCAAGATATTTTAGAAGTTGTTCAAGCTACAAAA
GGTTTTTCTGGAGCTGATATGACAAACCTTTGTAAGGAGGCAGCTTTAATACCTATCCGT
CAATGTACTGATATAACAAACATATAGTCTAGTGATATTCGTCCTATCAATAAATCAGAT
TTTGTAAAGTCACTAAAATAAGTTAAAGCTACAGTAACTTCAAAAGATTTAGCTGGATAT
TTTGATTGGAATAACTAATTTGGTAGTTTTGAAATAAATATGGAAGAAATAGATTCCTGA

>TTHERM_00088010(gene)
ATGCTTTCTACTTATAAAGATGCTGGGGATGGGGGATTGTAATAAGATAATTTAATTCCA
ATGTAGAAGGAAACCCTTAAGAGTATTTTATCCAGCTTTAAAAATAAGATGAATGAGACT
CATTAATTGTATTCTTAAAATTCAAACTCTCTTCAAAAAGAAGATAAAGAAGATGTATAT
AAACATGCTTTTTCTTTCGCTTTTCTACTTTAAAAGTATTAAGAGAAAGACAACTCACTA
TGTTTAGAAGATTTTATTTAAGAAGCTGAACGAATGAGAGATCATCAGTTATACAAACCA
AGCAAGGCTAATAAAAAGTTTAATATAATGCCAAAAATATCTAAAGAAAAGTTTGAGTAA
TTTATAGAATATGAAAAAGATACAAGATTTCCTCAACCTAGAAAAACAGTACAGTTAAAT
ACTCAAGCAAGACTTCCAGAAAGACAAACATCAAATTAAAAGCCTGCAATAAGTAGTTTA
TTGAATAGCAATAATAATTAAATCTCATCCAACTCTAATTAAGGATATGGGAATATAAAT
AGTTTTTAGAACAATCCTAATAATAGTATTGATAATAATAAAAATAATAATAATAATTTT
GGTCCTACTTAACAAAATAATAACAATGGGTTTTATAGATCTCAAAGCAGTTAAAATTAA
GATGAACAACCATAAAAAACAAATGGATATAAATAATAGTATAACAATGGCTACAACAGC
TATTAAAATTAAAATACAAATAATTTTGGGTATGGTAGAAATAGGTATCAAAATAACAAT
AGATATAATAAAGGAAGGGAGTAAATTGAAGAAGAATAAGATGAGTAATAGTAAGCTGGA
GGTTTTAAAACAGCATCAGAATAAAGATATTAAAATAATATGTTAAAGAGATAAAAAGAA
GAAGGATTCTATAATAAAGAAACTGGAAAATATGGTAGAAATAATGGATAGCTAGAGTTT
GAAGGTGTGAATGATAATAAACCTAAATACGGATATACAAAATATGGAAGTAACTAGGGA
GTTGATGATGTTGTTAATCTTGTCCATTACCATACTATAGGGAAAAACCTCAATTTAAAT
AATAATTCTTCATCTAATTAAGCTGCTGCCTTAAATGGAGGTGGTACAGAAGACGAATAT
AAAAAGACAGGACTAAGCAGAAAATTCAAACCTCCAGGAGCACCTGGTTCAAATACCGGA
GGGAAAAAAAATGAATAGTGTGAGCAGCTCAAAGGAATGGATTAAAAAGTAAAATTTATT
AAAACAGATTTTAGTTATTAAAAATTTTTTTCATAAAGTTAATAGATTTAATTGAAAACG
AAATTGTAGAAAATGCTGCTAATGTTAAGTGGGAAGATATAGCTGGTTTAAGTTCAGCTA
AGGAATCTGTCAAGGAAACTATAGTTTGGCCTATGTTGAACCCATAAATCTTTACTGGTA
TTAGAGCTCCTCCTAAAGTAAAAAACATTTTAAATTTAATAGTTAATTTAATATTTAATT
ATAGGGTCTTCTCTTGTTTGGACCACCTGGAACAGGTAAGACTATGATTGGCAAGGCTAT
TGCTAATCAATCTGGCTCTACATTTTTTTCTATATCAGCATCTTCTCTAACAAGTAAATA
TATTGGTGAAGGTGAGAAAATGGTAAAAATTCTCTTCAAGCTAGCAGAAATGAGATAACC
AAGTGTTATTTTTATTGATGAAATAGACTCACTTTTATGTGCAAGATAAGAAGTAAAATA
AATAATAATAAAATTAAATATAAATTTATTTTAGCCTAATTGCTAAAATTTAAGATAAAA
CAAAAAATTATTTACAAATTTAAAATTTTTAGAATGAAAATGAGGCAAGTAGAAGAATTA
AGACAGAGTTTTTAGTTTAAATGGAAGGTGCTACTTCAAGAGAAGAAGTAAGATTGTTAC
TTATAGGAGCAACAAATAGGCCATAAGAACTTGATGATGTGATTAATTTTCAAAATTTTG
GATTTCATAATCTAATTTATTTTATTAATAGGCTGTTAGAAGAAGATTTGTTAAGAAATT
ATATATTCCTCTACCTAATATGGTAGCAAGAGAGTAATTGATAAGAAGAGTAATTGAAAG
AGAATCAGCAAAAGGAAACGCTTTTGATATGAGCGACCAAGTAAAAAATTAATTGCATAT
AAGAAATACTAAGAAGATAAATTATTCATTTTTAATTTTAAAAATTTATAATAAATAGGA
TATTTTAGAAGTTGTTCAAGCTACAAAAGGTTTTTCTGGAGCTGATATGACAAACCTTTG
TAAGGAGGCAGCTTTAATACCTATCCGTCAATGTACTGATATAACAAACATATAGTCTAG
TGATATTCGTCCTATCAATAAATCAGATTTTGTAAAGTCACTAAAATAAGTTAAAGCTAC
AGTAACTTCAAAAGATTTAGCTGGATATTTTGATTGGAATAACTAATTTGGTAGTTTTGA
AATAAATATGGAAGAAATAGATTCCTGA

>TTHERM_00088010(protein)
MLSTYKDAGDGGLQQDNLIPMQKETLKSILSSFKNKMNETHQLYSQNSNSLQKEDKEDVY
KHAFSFAFLLQKYQEKDNSLCLEDFIQEAERMRDHQLYKPSKANKKFNIMPKISKEKFEQ
FIEYEKDTRFPQPRKTVQLNTQARLPERQTSNQKPAISSLLNSNNNQISSNSNQGYGNIN
SFQNNPNNSIDNNKNNNNNFGPTQQNNNNGFYRSQSSQNQDEQPQKTNGYKQQYNNGYNS
YQNQNTNNFGYGRNRYQNNNRYNKGREQIEEEQDEQQQAGGFKTASEQRYQNNMLKRQKE
EGFYNKETGKYGRNNGQLEFEGVNDNKPKYGYTKYGSNQGVDDVVNLVHYHTIGKNLNLN
NNSSSNQAAALNGGGTEDEYKKTGLSRKFKPPGAPGSNTGGKKNEQCEQLKGMDQKLIDL
IENEIVENAANVKWEDIAGLSSAKESVKETIVWPMLNPQIFTGIRAPPKGLLLFGPPGTG
KTMIGKAIANQSGSTFFSISASSLTSKYIGEGEKMVKILFKLAEMRQPSVIFIDEIDSLL
CARQENENEASRRIKTEFLVQMEGATSREEVRLLLIGATNRPQELDDAVRRRFVKKLYIP
LPNMVAREQLIRRVIERESAKGNAFDMSDQDILEVVQATKGFSGADMTNLCKEAALIPIR
QCTDITNIQSSDIRPINKSDFVKSLKQVKATVTSKDLAGYFDWNNQFGSFEINMEEIDS