Identifiers and Description

Gene Model Identifier

TTHERM_00094000

Standard Name

RDN2 (RDr1-associated Nucleotidyltransferase)

Aliases

PreTt16555 | 6.m00629 | 3836.m02213

Description

RDN2 RNA-dependent RNA polymerase-associated nucleotidyltransferase; Nucleotidyltransferase; exhibits RNA terminal uridine transferase activity in vitro; involved in 23-24 nt small RNA metabolism

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Domains

  • ( PF01909 ) Nucleotidyltransferase domain
  • ( PF03828 ) Cid1 family poly A polymerase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_02566.1 2.0004485223439647e-69
Description: hypothetical protein (538 aa)
DictyBase DDB_G0268914 0.00000000000009996062864481225
Description: DDB_G0268914 on chromosome: 1 position 2371552 to 2385174
Oxytricha Contig10883.0.g40 0.000000000004997916451710233
Description: Nucleotidyltransferase domain
WormBase WBGene00001596 0.0000000039998859049333245
Description: locus:gld-2 Poly(A) RNA polymerase gld-2 status:Confirmed UniProt:O17087 protein_id:CCD72661.1
WormBase WBGene00013762 0.0000000039998859049333245
Description: status:Partially_confirmed UniProt:Q9NAL5 protein_id:CAB76739.2

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:22706992: Talsky KB, Collins K (2012) Strand-asymmetric endogenous Tetrahymena small RNA production requires a previously uncharacterized uridylyltransferase protein partner. RNA (New York, N.Y.) 18(8):1553-62
  2. Ref:20622019: Talsky KB, Collins K (2010) Initiation by a eukaryotic RNA-dependent RNA polymerase requires looping of the template end and is influenced by the template-tailing activity of an associated uridyltransferase. The Journal of biological chemistry 285(36):27614-23
  3. Ref:19656801: Couvillion MT, Lee SR, Hogstad B, Malone CD, Tonkin LA, Sachidanandam R, Hannon GJ, Collins K (2009) Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila. Genes & development 23(17):2016-32
  4. Ref:19451546: Lee SR, Talsky KB, Collins K (2009) A single RNA-dependent RNA polymerase assembles with mutually exclusive nucleotidyl transferase subunits to direct different pathways of small RNA biogenesis. RNA (New York, N.Y.) 15(7):1363-74

Sequences 

>TTHERM_00094000(coding)
ATGGAAGGCGATTTCTTTTAGCAAACATTTCTAAAATATATAAAGTATAGACCAAGCAAG
AATATAAATGTGCATTAGTATTTATTGAAGAAATTAGAAGTTGAGTAATTAAGTTAAAGT
TAATTATTAAGCTTAAAAAATAGTTTAGATGATTTTATTCGTAAATATAATTTTCATAAT
GATGAATGGATTCTAATTAGTCTAATTGAAAATTTAGCACATTCAGACTTATTATTTTCA
AGCGATACTGAAAAATATATTTTAATTATTAAGAAAAGATTCTACCTCAATTTACTGAAT
AAACTTGAGAATAATATTTCAAGTAAATTTGATCTTTAGGAGCTCTAGAAGTGTTTAAAG
TCATTTTACTTAAGCTATAAAAATAATGTTTATGATTTGTTTTTAAATGCTTCAAATGAT
ATTTAAATAATAAAGTAGATAGATAGCAACCTAGGAGAAAAATTAAAAAAAATTGAAAAG
CATGTATCTGAGATTTTAAAGAGGCTTAAAAGTAATGAATCGTAGTAAATGTCTATTAAT
TAGAATGAGTAGAACATCTAATAAAATAAAGAAAATATTAATGAAATAACCAGTAGCAAT
TAATTAGAAATTTTATTAAATTAAATTTATAAGTAAGAAAAGATCAGTATTTAGTTTAAT
GAAGAATTACTTAATCAAGAAGTCAATATGGTAAATTAAATTGTGAGTGAGATGAATTTA
AATAAAATTATTGGGCTATAAAATGTGTATGTTCATCCGTATGGGTCAGTTGTTAGTGGG
TTTGGTTAGAATGATAGTGACATTGATATAAGCATAAATACAGATTGCTATTTAGATGAA
AGAGTATTTCTTTCTCTTATTTATGATTTCATGAAAAATTATTTGCATAAATATAAAATC
AAATATTAAAAACTTGAATTAAAATTAGATGCGCGTATTCCTTTAATAACTCTTGTTAAA
CAGAAAGATAATGTTAATTTGAAAAGTAATACAGTTTCAATAGACATATGTATAAATAAT
CTACTAGGATGCGCAAATTCAAAAATGCTAAAAGTTATATCTTAGATTCATCCCTTAGTA
AAGTAGCTAGGAATAATCATTAAATATTGGGCGAAGTAGAATGGTCTTATAAGCAAAAAA
ACTCTTAGTTCATATGCATTTATCCTCATAATGATCTGCTTTTTATAGAGAAAGAAGCTA
ATTGATCCTTATTTTTAAGAGAAAGTTTAAAAAAGATAAAGTGATCCAAAATATTCTACT
TTGATTAAGAGGACAAAGGAAACTGATTAGGAATTTTAAACAAACCTTTATTATGTGCAA
GATCCCTCGCATTTACAGAAATCTCTAAAAAAGTATAAAGAAAACAATCCAAACTAAAAA
ACTTTATTAGACATGAATCTTGCAAGCTTATTCAGTGAGTTTATTGAATATTACTCAGAC
ACCACTGATGAGAATAGAAGATATATAGATATTATGAATAATTATATAGTAAAATCATAT
AATAAAAATTTATTCTTTTATATTATTGACCCATTTGATAATTATCATAACCCAGGAGAA
AGAAGCAGAGTAGAGAATATAGATGATAACATATTTATAAATAGATTTAGGTTTGCTAAG
TAAAAATTGCAAGACAAACAATATTCGCAAATATTTGAATTAAAATTTCAATGA


>TTHERM_00094000(gene)
ATGGAAGGCGATTTCTTTTAGCAAACATTTCTAAAATATATAAAGTATAGACCAAGCAAG
AATATAAATGTGCATTAGTATTTATTGAAGAAATTAGAAGTTGAGTAATTAAGTTAAAGT
TAATTATTAAGCTTAAAAAATAGTTTAGATGATTTTATTCGTAAATATAATTTTCATAAT
GATGAATGGATTCTAATTAGTCTAATTGAAAATTTAGCACATTCAGACTTATTATTTTCA
AGCGATACTGAAAAATATATTTTAATTATTAAGAAAAGATTCTACCTCAATTTACTGAAT
AAACTTGAGAATAATATTTCAAGTAAATTTGATCTTTAGGAGCTCTAGAAGTGTTTAAAG
TCATTTTACTTAAGCTATAAAAATAATGTTTATGATTTGTTTTTAAATGCTTCAAATGAT
ATTTAAATAATAAAGTAGATAGATAGCAACCTAGGAGAAAAATTAAAAAAAATTGAAAAG
CATGTATCTGAGATTTTAAAGAGGCTTAAAAGTAATGAATCGTAGTAAATGTCTATTAAT
TAGAATGAGTAGAACATCTAATAAAATAAAGAAAATATTAATGAAATAACCAGTAGCAAT
TAATTAGAAATTTTATTAAATTAAATTTATAAGTAAGAAAAGATCAGTATTTAGTTTAAT
GAAGAATTACTTAATCAAGAAGTCAATATGGTAAATTAAATTGTGAGTGAGATGAATTTA
AATAAAATTATTGGGCTATAAAATGTGTATGTTCATCCGTATGGGTCAGTTGTTAGTGGG
TTTGGTTAGAATGATAGTGACATTGATATAAGCATAAATACAGATTGCTATTTAGATGAA
AGAGTATTTCTTTCTCTTATTTATGATTTCATGAAAAATTATTTGCATAAATATAAAATC
AAATATTAAAAACTTGAATTAAAATTAGATGCGCGTATTCCTTTAATAACTCTTGTTAAA
CAGAAAGATAATGTTAATTTGAAAAGTAATACAGTTTCAATAGACATATGTATAAATAAT
CTACTAGGATGCGCAAATTCAAAAATGCTAAAAGTTATATCTTAGATTCATCCCTTAGTA
AAGTAGCTAGGAATAATCATTAAATATTGGGCGAAGTAGAATGGTCTTATAAGCAAAAAA
ACTCTTAGTTCATATGCATTTATCCTCATAATGATCTGCTTTTTATAGAGAAAGAAGCTA
ATTGATCCTTATTTTTAAGAGAAAGTTTAAAAAAGATAAAGTGATCCAAAATATTCTACT
TTGATTAAGAGGACAAAGGAAACTGATTAGGAATTTTAAACAAACCTTTATTATGTGCAA
GATCCCTCGCATTTACAGAAATCTCTAAAAAAGTATAAAGAAAACAATCCAAACTAAAAA
ACTTTATTAGACATGAATCTTGCAAGCTTATTCAGTGAGTTTATTGAATATTACTCAGAC
ACCACTGATGAGAATAGAAGATATATAGATATTATGAATAATTATATAGTAAAATCATAT
AATAAAAATTTATTCTTTTATATTATTGACCCATTTGATAATTATCATAACCCAGGAGAA
AGAAGCAGAGTAGAGAATATAGATGATAACATATTTATAAATAGATTTAGGTTTGCTAAG
TAAAAATTGCAAGACAAACAATATTCGCAAATATTTGAATTAAAATTTCAATGA


>TTHERM_00094000(protein)
MEGDFFQQTFLKYIKYRPSKNINVHQYLLKKLEVEQLSQSQLLSLKNSLDDFIRKYNFHN
DEWILISLIENLAHSDLLFSSDTEKYILIIKKRFYLNLLNKLENNISSKFDLQELQKCLK
SFYLSYKNNVYDLFLNASNDIQIIKQIDSNLGEKLKKIEKHVSEILKRLKSNESQQMSIN
QNEQNIQQNKENINEITSSNQLEILLNQIYKQEKISIQFNEELLNQEVNMVNQIVSEMNL
NKIIGLQNVYVHPYGSVVSGFGQNDSDIDISINTDCYLDERVFLSLIYDFMKNYLHKYKI
KYQKLELKLDARIPLITLVKQKDNVNLKSNTVSIDICINNLLGCANSKMLKVISQIHPLV
KQLGIIIKYWAKQNGLISKKTLSSYAFILIMICFLQRKKLIDPYFQEKVQKRQSDPKYST
LIKRTKETDQEFQTNLYYVQDPSHLQKSLKKYKENNPNQKTLLDMNLASLFSEFIEYYSD
TTDENRRYIDIMNNYIVKSYNKNLFFYIIDPFDNYHNPGERSRVENIDDNIFINRFRFAK
QKLQDKQYSQIFELKFQ