Identifiers and Description

Gene Model Identifier

TTHERM_00094210

Standard Name

RPC5 (RNA polymerases I and III subunit 5)

Aliases

PreTt16576 | 6.m00650 | 3836.m02233

Description

RPC5 DNA-directed RNA polymerase I and III subunit RPAC1; Fifth largest subunit of RNA polymerases I and III; homolog of RPC40 in yeasts and RPA40 in humans; expressed in macronucleus of vegetative cells and weakly in early stages of conjugation

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• DNA-directed 5'-3' RNA polymerase activity (IEA) | GO:0003899
• protein dimerization activity (IEA) | GO:0046983

Biological Process

• transcription (IEA) | GO:0006350

Domains

• ( PF01000 ) RNA polymerase Rpb3/RpoA insert domain
• ( PF01193 ) RNA polymerase Rpb3/Rpb11 dimerisation domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

• ( SD02176 ) Macronucleus: HA tagged RPC5
• ( SD02718 ) Macronucleus: HA tagged RPC5

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_02582.1	9.997093137033517e-262
	Description: DNA-directed RNA polymerase I polypeptide (340 aa)
Oxytricha	Contig22041.0.g30	9.995094197784295e-101
	Description: RNA polymerase Rpb3/RpoA insert domain
DictyBase	DDB_G0282339	8.003693242657371e-87
	Description: rpa5 on chromosome: 3 position 5656917 to 5658092
WormBase	WBGene00019275	2.0004485223439647e-69
	Description: locus:rpac-40 status:Confirmed UniProt:Q9UAY9 protein_id:CCD68663.1
SGD	YPR110C	3.0000115468388957e-66
	Description: RPC40 RNA polymerase subunit AC40, common to RNA polymerase I and III
Stentor Coeruleus	SteCoe_7522	3.0144087850653746e-40
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15470252: Mochizuki K, Gorovsky MA (2004) RNA polymerase II localizes in Tetrahymena thermophila meiotic micronuclei when micronuclear transcription associated with genome rearrangement occurs. Eukaryotic cell 3(5):1233-40

Sequences

>TTHERM_00094210(coding)
ATGTCAAATAAAACTTAAAAAATGAAGAAAAATATTGTCTTCACCAACGAAGGCATTCAA
CACAGCTAGGAAATGAACTATAGCGCTGCTTTTACTAGTGAAGAAGATTTCAATACATTC
AAGGAAAACATTAAAATAGAAGTTATTAGATATGATAATAAAAATAAAGAATTAGAATTT
GATTTAATGGGTGTCGATGCTCCTATTGCTAACGCTTTGAGAAGAATTATGATTGCAGAA
GTTCCTACAATGGCTATCCACAAGGTTTATATTTACTAAAATACTTCTATTATTCCTGAT
GAAGTTTTGGCTCACAGACTTGGTTTAATTCCTATTTATGCTGACCCTCGTCTTTTCGAA
GAAAAGCAAGAAGAAGACGAGTATAATGAAAAAAATTCTTTAAAGTTTACATTAAAGATT
AAATGCTCTAAGAAAGAATAGTACAAAAATTACTCTGAAGCTGATTTAGAAAATTTAACA
CCTGAAACCTACTTAGAAAATGCTATTGTCTATAGCGGTGATTTCAAATGGGTTTCTTAA
GGAGAATAAAATAAAAAATTTGAAGAGAATCCAATCAGAATGGTCCATGATAATATTATT
GTAGCTAAGTTAAGAGAAAACCAAGAAATTATTTGTGAAGTTATTTGTTAAAAGGGTATT
GGAAAAACACATGCCAAATGGTCTCCTGTTTGTACTGCTTACTATCGTTTAATGCCTGAA
ATAAACATAAATAGTGATATCACCGGAGCTAAAGCTCAAGAATTGAAAGAACGTTGCCCT
CTTAAAGTTTATGATGTTTAAAATAATAAGGCTATTGTTTCTAACGAAAGAGCTTGCACT
ATGTGCAGAGAATGCATAAGAGAAGATGAAGAATTCAATTCAAAGATTGAATTGGCCAAA
AAGAAAGAGCATTTTATTTTTACTGTAGAAAGCGTTGGAATCTACGAACCTCACGAGATA
GTAAAGGAAGCAATCTAGATATTAAAATAAAAAGCATCTAGTTTTATGCTAAACCTATGA

>TTHERM_00094210(gene)
ATGTCAAATAAAACTTAAAAAATGAAGAAAAATATTGTCTTCACCAACGAAGGCATTCAA
CACGTATAGATTAAAAATCATTTTTTTATTTTAAATAAAAGTGTTCAAAGAACTAAGCAA
TTTTAGCCAATTTCATCATATTTACTAAATTAGAATCTTTAATGAAGTATTTAATCAGGA
AATCTAAAAAATGATTTCTAAATTTGATGAATTAGAAAATGAATTAACAAATTTAATCAA
ATAAAAATTCTATATCAAATTTAAATGAGCTTAAACATATTTTATCTTATCAAAAGAGCT
AGGAAATGAACTATAGCGCTGCTTTTACTAGTGAAGAAGATTTCAATACATTCAAGGAAA
ACATTAAAATAGAAGTTATTAGATATGATAATAAAAATAAAGAATTAGAATTTGATTTAA
TGGGTGTCGATGCTCCTATTGCTAACGCTTTGAGAAGAATTATGATTGCAGAAGTATATT
ATTTTTCTTTTTTTCAAATTTTTAGTTTTCTTGAGCGAAAATTATCATTAGTTTCTAAAA
TACTATTAAAAATTAATAGGTTCCTACAATGGCTATCCACAAGGTTTATATTTACTAAAA
TACTTCTATTATTCCTGATGAAGTTTTGGCTCACAGACTTGGTTTAATTCCTATTTATGC
TGACCCTCGTCTTTTCGAAGAAAAGCAAGGTAAATTCATTTTATAAAATTAAAGAAGAAG
ATTTATTTATAAACAAGATTTTATAGCAATAAAAAAGTAAAGTGGATAGATAGCTAAATT
AATTAATTCTTAATTTTTATATAAATTATTTTATTTACTGCTTTTGAATTTAATAATAAT
CAAATTTTAAATAATAAATTTAGAAGAAGACGAGTATAATGAAAAAAATTCTTTAAAGTT
TACATTAAAGATTAAATGCTCTAAGAAAGAATAGTACAAAAATTACTCTGAAGCTGATTT
AGAAAATTTAACACCTGAAACCTACTTAGAAAATGCTATTGTAAGATAAATTTTTTGATT
TAGGAAGCGAATTTTTAAATGATCTAATACATTTTAATTAGGTCTATAGCGGTGATTTCA
AATGGGTTTCTTAAGGAGAATAAAATAAAAAATTTGAAGAGAATCCAATCAGAATGGTCC
ATGATAATATTATTGTAGCTAAGTTAAGAGAAAACCAAGAAATTATTTGTGAAGTTATTT
GTTAAAAGGGTATTGGAAAAACACATGCCAAATGGTCTCCTGTTTGTACTGCTTACTATC
GTTTAATGCCTGAAATAAACATAAATAGTGATATCACCGGAGCTAAAGCTCAAGAATTGA
AAGAACGTTGCCCTCTTAAAGTTTATGATGTTTAAAGTAATTTAAAATAATTAATATTAA
ATTAACATCAGCTAATATAAATAAAACTATCTATTTTAATAGATATTTAATATTTTTTAT
TATTCTGTAAACAAATACCAAACAAGTATCAAGTCAATTTCTGATAACTAAAAATTGATT
TCTTGCTAAATTATAATTATCAAAAAATTACTTGTTTGTTAGATATAAATAAAAAGACAC
AGCTAATACAAATCAAATATTAATTATATTCTAAAATTTATTGGTCTAAAATTATGATCT
AAAAAAAATATCTAAGACTTTATATAGCTTAAAAAATTTTTTGTTTACTTAAATTAAATT
AATTTTTATAAATAGATAATAAGGCTATTGTTTCTAACGAAAGAGCTTGCACTATGTGCA
GAGAATGCATAAGAGAAGATGAAGAATTCAATTCAAAGATTGAATTGGCCAAAAAGAAAG
AGCATTTTATTTGTAAAATATTCATTATATTTAGATTAAATTGATAGGAATTTATATAAG
AAATAATAATTTTACTGATCGGAAAGGGAAGATATAGAAAAATTAATTAATTTGGATTTA
AGCTAATTTAATATATTTATTAGTTAAAATTACAATAATTACCTTATATTAATTTATATT
TTTAATATGCAAATAGTTACTGTAGAAAGCGTTGGAATCTACGAACCTCACGAGATAGTA
AAGGAAGCAATCTAGATATTAAAATAAAAAGCATCTAGTTTTATGCTAAACCTATGA

>TTHERM_00094210(protein)
MSNKTQKMKKNIVFTNEGIQHSQEMNYSAAFTSEEDFNTFKENIKIEVIRYDNKNKELEF
DLMGVDAPIANALRRIMIAEVPTMAIHKVYIYQNTSIIPDEVLAHRLGLIPIYADPRLFE
EKQEEDEYNEKNSLKFTLKIKCSKKEQYKNYSEADLENLTPETYLENAIVYSGDFKWVSQ
GEQNKKFEENPIRMVHDNIIVAKLRENQEIICEVICQKGIGKTHAKWSPVCTAYYRLMPE
ININSDITGAKAQELKERCPLKVYDVQNNKAIVSNERACTMCRECIREDEEFNSKIELAK
KKEHFIFTVESVGIYEPHEIVKEAIQILKQKASSFMLNL