Identifiers and Description

Gene Model Identifier

TTHERM_00105110

Standard Name

HSP70 (Heat Shock Protein 70)

Aliases

hsp70 | PreTt23013 | 7.m00462 | HSP70A

Description

HSP70 heat shock 70 kDa protein; Putative 70-kDa heat-shock protein (hsp70); two forms of hsp70 associate with tubulin; mitochondrial hsp70 associates with 14-nm filament protein (14FP); hsp70 proteins have evolutionarily conserved roles in folding nascent polypeptides; hypothetical protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:25586926: Fukuda Y, Akematsu T, Attiq R, Tada C, Nakai Y, Pearlman RE (2015) Role of the Cytosolic Heat Shock Protein 70 Ssa5 in the Ciliate Protozoan Tetrahymena thermophila. The Journal of eukaryotic microbiology 62(4):481-93
  2. Ref:18055912: Barchetta S, La Terza A, Ballarini P, Pucciarelli S, Miceli C (2008) Combination of two regulatory elements in the Tetrahymena thermophila HSP70-1 gene controls heat shock activation. Eukaryotic cell 7(2):379-86
  3. Ref:17189490: Xie R, Clark KM, Gorovsky MA (2007) Endoplasmic reticulum retention signal-dependent glycylation of the Hsp70/Grp170-related Pgp1p in Tetrahymena. Eukaryotic cell 6(3):388-97
  4. Ref:17959197: Smith DG, Gawryluk RM, Spencer DF, Pearlman RE, Siu KW, Gray MW (2007) Exploring the mitochondrial proteome of the ciliate protozoon Tetrahymena thermophila: direct analysis by tandem mass spectrometry. Journal of molecular biology 374(3):837-63
  5. Ref:11260259: Takeda T, Yoshihama I, Numata O (2001) Identification of Tetrahymena hsp60 as a 14-nm filament protein/citrate synthase-binding protein and its possible involvement in the oral apparatus formation. Genes to cells : devoted to molecular & cellular mechanisms 6(2):139-49
  6. Ref:9247200: Williams NE, Nelsen EM (1997) HSP70 and HSP90 homologs are associated with tubulin in hetero-oligomeric complexes, cilia and the cortex of Tetrahymena. Journal of cell science 110 ( Pt 14)( ):1665-72
  7. Ref:8102520: Hendrick JP and Hartl FU (1993) Molecular chaperone functions of heat-shock proteins. Annu Rev Biochem 62():349-84
  8. Ref:8357830: Amaral MD, Galego L, Rodrigues-Pousada C (1993) Heat-shock-induced protein synthesis is responsible for the switch-off of hsp70 transcription in Tetrahymena. Biochimica et biophysica acta 1174(2):133-42
  9. Ref:8102139: Soares H, Galego L, Cóias R, Rodrigues-Pousada C (1993) The mechanisms of tubulin messenger regulation during Tetrahymena pyriformis reciliation. The Journal of biological chemistry 268(22):16623-30
  10. Ref:2663194: Martindale DW, Gu ZM, Csank C (1989) Isolation and complete sequence of the yeast isoleucyl-tRNA synthetase gene (ILS1). Current genetics 15(2):99-106

Sequences 

>TTHERM_00105110(coding)
ATGGCTGACAAGAAAGCTGAAGGTGGTATCGGTATCGGTATCGATTTAGGTACTACTTAC
TCCTGCGTTGGTGTTTTCATTAACGACAGAGTTGAAATCATTGCTAACGATTAAGGTAAC
AGAACCACTCCCTCTTACGTTGCATTCACCGAAACTGAAAGACTTATTGGTGATGCCGCC
AAGAACTAAGTTGCTAGAAATCCTACCAACACCGTTTTTGATGCCAAGAGACTTATCGGT
AGAAAGTTCAATGAAACCGTCGTCCAAAAGGATATCAAGTTATGGCCCTTCAAGGTTGAA
GCTGGTCCTGATGACAAGCCCAAGATCGTCGTTAAGCACAAAGGTGAAGTCAAGAAGTTC
CACGCTGAAGAAATCTCTTCCATGGTTCTCGTTAAGATGAGAGAAATCGCTGAAGCCTTC
TTGACCAAGTAAATCAAGAACGCCGTCATTACCGTCCCTGCTTACTTCAATGACTCCCAA
AGACAAGCTACCAAGGATGCTGGTGCCATCGCTGGTTTGAACGTTTTGAGAATCATCAAC
GAACCCACTGCCGCCGCTATTGCTTACGGTTTGGACAAGAAGGGTCAAGGTGAAAAGAAC
GTCCTCATCTTCGATTTGGGTGGTGGTACTTTCGATGTCTCCCTCCTTACTCTTGATGAC
GGTATCTTCGAAGTCAAGGCCACTGCTGGTGATACTCACTTGGGTGGTGAAGATTTCGAT
AACAAGCTCGTCGAATTCTGCGCTGCTGACTTCTTAAAGAAGAAGAACATCGATATCAGA
GAAAACCCCAGAGCCATGAGAAGATTAAGAACTCAATGCGAAAGAGCTAAAAGAATTCTT
TCTTCTTCTGCTCAAGCCACCATCGAAGTCGATGCTTTGGCTGATTCCGAAGATTTCATG
ATGGTCATCTCCAGACCCAAATTCGAAGAATTATGTCTTTCTATGTTCAAGGAATGTATC
CCCCCTGTCGAAAAGGTCCTCAAGGACTCCGGTATGGCCAAGAACCAAGTCCACGAAGTC
GTCCTCGTCGGTGGTTCCACTCGTATCCCCAAGGTCATCCAACTCATTACCGAATTCTTC
AACGGTAAGGAACCCAACAGATCCATCAACCCCGATGAAGCCGTCGCTTACGGTGCTGCC
ATTCAAGCTGCTATCTTGACTGGTTCTGGTTCTGAACACATCCAAGACGTCCTTCTTCTC
GACGTTACCCCTCTTTCCATGGGTATCGAAACTGCTGGTCAAGTCATGACTGTCTTGATC
CCCAGAAACACCACCATCCCCACCAAGAAGTCCCAAGTCTTCACCACTTATGCTGATAAC
CAACCTGGTGTCCTCATTCAAGTCTTCGAAGGTGAAAGACCCATGACCAAGGATAACCAT
CTCTTGGGTAAGTTCAACCTCGACGGTATTGCCCCTGCTCCCAGAGGTGTTCCTCAAATC
GAAGTCTCCTTCGATATTGATGAAAACGGTATCCTCAACGTTACTGCCACTGATAAGGGT
ACTTCCAAGTCCAACAAGATTACCATCACCAACCAAAAGGGTAGATTATCCCAAGATGAA
ATCGACAGACTTATCAAGGAAGCTGAAAAATTCAAGGGTGAAGATGAAGCCTTAAAGAAG
AAGGTTGAAGCCAAGAACGGTCTTGAAAACTACACCTACTCCATCAGAAACTCCCTTAAG
GACGAAAAGCTTAAGGACAAGTTCTCTGCTGAAGAAAGAGAAAAGGTTCAAAAGCTCGTC
GACGAAACCTCCAAGTGGCTCGAAGAAAACCACAATGCTGAAGCTGAAGAATACAGCCAC
AAGCAAAAGGCTTTGGAAGAAGTCTTCAACCCCATCATGATGAGAGTCTACCAATCTACT
GGTGGTGTTCCCCCTGGTGCTGATATGGGTGGTGCTGGTTTCCCTGGCAGCGGCTCTGCT
CCCACTGGTGGTGCCTCCAACGTCGATGAAGTCGATTGA



>TTHERM_00105110(gene)
ATTAATTAAATTAATAAAAAATCCTAATTTCTTTCTCCAAAAAGAATTTAAAAACAAACA
AAATCAAGCAAAATAAACATAATAAATAAAAATGGCTGACAAGAAAGCTGAAGGTGGTAT
CGGTATCGGTATCGATTTAGGTACTACTTACTCCTGCGTTGGTGTTTTCATTAACGACAG
AGTTGAAATCATTGCTAACGATTAAGGTAACAGAACCACTCCCTCTTACGTTGCATTCAC
CGAAACTGAAAGACTTATTGGTGATGCCGCCAAGAACTAAGTTGCTAGAAATCCTACCAA
CACCGTTTTTGATGCCAAGAGACTTATCGGTAGAAAGTTCAATGAAACCGTCGTCCAAAA
GGATATCAAGTTATGGCCCTTCAAGGTTGAAGCTGGTCCTGATGACAAGCCCAAGATCGT
CGTTAAGCACAAAGGTGAAGTCAAGAAGTTCCACGCTGAAGAAATCTCTTCCATGGTTCT
CGTTAAGATGAGAGAAATCGCTGAAGCCTTCTTGACCAAGTAAATCAAGAACGCCGTCAT
TACCGTCCCTGCTTACTTCAATGACTCCCAAAGACAAGCTACCAAGGATGCTGGTGCCAT
CGCTGGTTTGAACGTTTTGAGAATCATCAACGAACCCACTGCCGCCGCTATTGCTTACGG
TTTGGACAAGAAGGGTCAAGGTGAAAAGAACGTCCTCATCTTCGATTTGGGTGGTGGTAC
TTTCGATGTCTCCCTCCTTACTCTTGATGACGGTATCTTCGAAGTCAAGGCCACTGCTGG
TGATACTCACTTGGGTGGTGAAGATTTCGATAACAAGCTCGTCGAATTCTGCGCTGCTGA
CTTCTTAAAGAAGAAGAACATCGATATCAGAGAAAACCCCAGAGCCATGAGAAGATTAAG
AACTCAATGCGAAAGAGCTAAAAGAATTCTTTCTTCTTCTGCTCAAGCCACCATCGAAGT
CGATGCTTTGGCTGATTCCGAAGATTTCATGATGGTCATCTCCAGACCCAAATTCGAAGA
ATTATGTCTTTCTATGTTCAAGGAATGTATCCCCCCTGTCGAAAAGGTCCTCAAGGACTC
CGGTATGGCCAAGAACCAAGTCCACGAAGTCGTCCTCGTCGGTGGTTCCACTCGTATCCC
CAAGGTCATCCAACTCATTACCGAATTCTTCAACGGTAAGGAACCCAACAGATCCATCAA
CCCCGATGAAGCCGTCGCTTACGGTGCTGCCATTCAAGCTGCTATCTTGACTGGTTCTGG
TTCTGAACACATCCAAGACGTCCTTCTTCTCGACGTTACCCCTCTTTCCATGGGTATCGA
AACTGCTGGTCAAGTCATGACTGTCTTGATCCCCAGAAACACCACCATCCCCACCAAGAA
GTCCCAAGTCTTCACCACTTATGCTGATAACCAACCTGGTGTCCTCATTCAAGTCTTCGA
AGGTGAAAGACCCATGACCAAGGATAACCATCTCTTGGGTAAGTTCAACCTCGACGGTAT
TGCCCCTGCTCCCAGAGGTGTTCCTCAAATCGAAGTCTCCTTCGATATTGATGAAAACGG
TATCCTCAACGTTACTGCCACTGATAAGGGTACTTCCAAGTCCAACAAGATTACCATCAC
CAACCAAAAGGGTAGATTATCCCAAGATGAAATCGACAGACTTATCAAGGAAGCTGAAAA
ATTCAAGGGTGAAGATGAAGCCTTAAAGAAGAAGGTTGAAGCCAAGAACGGTCTTGAAAA
CTACACCTACTCCATCAGAAACTCCCTTAAGGACGAAAAGCTTAAGGACAAGTTCTCTGC
TGAAGAAAGAGAAAAGGTTCAAAAGCTCGTCGACGAAACCTCCAAGTGGCTCGAAGAAAA
CCACAATGCTGAAGCTGAAGAATACAGCCACAAGCAAAAGGCTTTGGAAGAAGTCTTCAA
CCCCATCATGATGAGAGTCTACCAATCTACTGGTGGTGTTCCCCCTGGTGCTGATATGGG
TGGTGCTGGTTTCCCTGGCAGCGGCTCTGCTCCCACTGGTGGTGCCTCCAACGTCGATGA
AGTCGATTGAAAAACCAATTCAACTTAATTCATAACAAAATATTATTTTAATTTTTCTCT
TCTCTATAAACTCAATTTAATCCTTTTAATGTAATTACTTGTGCATATAATGTCTATGTG
TAAGAATATAATAATTAATTAATTATTATGTCAAAATTAA



>TTHERM_00105110(protein)
MADKKAEGGIGIGIDLGTTYSCVGVFINDRVEIIANDQGNRTTPSYVAFTETERLIGDAA
KNQVARNPTNTVFDAKRLIGRKFNETVVQKDIKLWPFKVEAGPDDKPKIVVKHKGEVKKF
HAEEISSMVLVKMREIAEAFLTKQIKNAVITVPAYFNDSQRQATKDAGAIAGLNVLRIIN
EPTAAAIAYGLDKKGQGEKNVLIFDLGGGTFDVSLLTLDDGIFEVKATAGDTHLGGEDFD
NKLVEFCAADFLKKKNIDIRENPRAMRRLRTQCERAKRILSSSAQATIEVDALADSEDFM
MVISRPKFEELCLSMFKECIPPVEKVLKDSGMAKNQVHEVVLVGGSTRIPKVIQLITEFF
NGKEPNRSINPDEAVAYGAAIQAAILTGSGSEHIQDVLLLDVTPLSMGIETAGQVMTVLI
PRNTTIPTKKSQVFTTYADNQPGVLIQVFEGERPMTKDNHLLGKFNLDGIAPAPRGVPQI
EVSFDIDENGILNVTATDKGTSKSNKITITNQKGRLSQDEIDRLIKEAEKFKGEDEALKK
KVEAKNGLENYTYSIRNSLKDEKLKDKFSAEEREKVQKLVDETSKWLEENHNAEAEEYSH
KQKALEEVFNPIMMRVYQSTGGVPPGADMGGAGFPGSGSAPTGGASNVDEVD