Identifiers and Description

Gene Model Identifier

TTHERM_00127000

Standard Name

TMLH1 (Tetrahymena homolog of budding yeast MLH1)

Aliases

PreTt09363 | 9.m00384 | 3699.m00093 | TTHERM_00127010

Description

TMLH1 DNA mismatch repair protein putative; DNA mismatch repair protein, C-terminal domain containing protein; DNA mismatch repair protein MutL/Mlh/Pms-like

Genome Browser (Macronucleus)



Genome Browser (Micronucleus)

External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF01119 ) DNA mismatch repair protein, C-terminal domain
  • ( PF13589 ) Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
  • ( PF16413 ) DNA mismatch repair protein Mlh1 C-terminus

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:23935123: Lukaszewicz A, Howard-Till RA, Loidl J (2013) Mus81 nuclease and Sgs1 helicase are essential for meiotic recombination in a protist lacking a synaptonemal complex. Nucleic acids research 41(20):9296-309

Sequences

>TTHERM_00127000(coding)
ATGAATCATTCCTAACCCTTAGAAAATACTGGTCCTCAGATCAAGAAGCTCCCATAAGAG
CTTATCGATAAGATTGCAGCTGGTGAAGTAGTACAACGTCCATCTGCAGCTGTTAAGGAG
CTTATTGAGAACTGTCTTGATGCTGGATCAAGTGAAATTTCAGTAGGGTTAGTATAAGGA
GGGTTAAAGTAGCTTATTGTAGAAGATAATGGTTCTGGAATTCACAAAGACGATTTTCCA
CTTCTCTGCGAAAGGTTTGCTACCTCTAAGATAAATGAGTTTAATGACCTTTAGAGTTTA
GTTTCATTTGGCTTTAGAGGAGAAGCGTTAGCCTCTATTTCTTTTGTCTCCAACTTGAAA
ATCACATCTCGAAAACCTAATTCTGACCTAGGATATAAAGCTAGTTTCAAAAACGGTGTT
ATGCTTGGTGAAGAGCCTGAAGCAGTGAACTGTACTGAAGGGACTACAGTAGATGTCTAG
GATTTATTTTTTAACTATGATGCAAGGAGAAAAAGTTTAAATGTTAACGAAGAAAAAAAA
AGAGTACTCAAATTGATCGGACAATTTGCTATGCATCATGCTAAATTGAGATTTAAATTT
AAAAGTGATAACCAAATTCAATTCTCATCTCACAGTGTGCTTGGCTCTACAGAATTGCAA
AGAAGAGAATAAATTATGTAGCAAATTACTAAGATTGCAGATAAAAGCTTTACTTCATGT
GAAAGTGAGTCGACAGAATATTAAGTTAAATTTAAAGGAACTTTTTCCAACATTGGAGCT
ACTAAAAAATACAAAGAAATCACTCTCTTTATAAATAATCGTTTGGTTGAATGTGAATCT
ATCAAAAAAGCAGTAGAACGCTCTTACCAGTCTTGTTATTAAAGTATTCATGAAGAAGAA
GGTGGATATTTTTGCTACTTGAGCTTAGAAATGAATCCAAAGAACTTGGATCCTAATGTT
CACCCAACAAAAAAAGAAGTCAAATTCTTATTTGAGTACGAAATAGCAAAAGAAATTGAA
TCATGGATTTTCGAAAATTTGAAAAATTGTGGAGTTATCAAACAACTTTCAGCAAATATT
TCATAAAGAACATCTTCATTTGAAACTTCAAATGTGAAAAGAAGTAGCTCAAGTCAATTA
TATTTTGGTTCTTAGAGCAATTTATCTAAGCAAAATTCTGATTACTATCAACCCACCAAG
CAAATTCGTGTAGATCCCAGAGATTAGAAAATTACTAGATTCTTTTCAGTAGAAAGCTCT
GAAGATGGAAATAACAATTCAAATCAAAAAAATTATCAAAGTATTAATTATATTGAAGAG
CAGAAAGAAGAACATCTAAACAGTCAAGATGATATTGCTGAAGAACCTGTTGATATGATT
AAAAAGAAAAAGATGCTCAATGAAGAAAGAAATTAAACTTCAATCAGTAATATAGGAAGC
TCTGACTAATTAGATGCTAATAATGCTCGTTCAAGTGTCATCGATAGGGCAAATTCTTAA
GTTAATGACCCACGTATTTAAGTATAATAATAGTTATTGTCTTTAAGGAATCAAGATATC
CATGATACAACAAGTTCTTTCTTTAAAAATCTTACGTATGTTGGCTGTATTTCTTCTAAT
CACTTTCTAGCTCAATTTAGAGATGATCTCTACCTTATAAACTCTATTCCATTATGTTAA
GAAATATTTAAATTTGAAATTCTGAGAAACTTTGGATAGATTAAGCCTGTAGAGCTAAAT
TAAGCAATAGGTTTGAAGGATATTTTAGAGTATTTTTTATTAAATTTTGATGAGATACCG
AATGAGAAAAAGGAGTTCCATCTGTCAAATATGGATACTTACATCGAGTAATTTGGCTTA
TTGAGTGACTTTTTAAGAGACTCCGTAGGCATAGTCATCAAAGATTAAAAGCTCTTGGCT
TTCCCTAATTTATTTAATTTATTTGAAAATGATAATAACTTTAAAGATATCTCATACATT
CTGTTGAGAATAATCACCAAAGTTAATTTTAGCGAAATACTCTAATCAGGTATGGGCTTA
GCAAACGAATTATCATTCTACTTTGCTTGGCAATTAGAAAAATCGTTTAAAAATTAATTG
TAAAGACAGCATTTCTAGGAAACGCAAAAGCAGAAATGGGACGATTTCTTTGAATAAAAA
ATGCTCCCAATGATTAAAAAAAAACTTTCACTCCCTAAATTAGATATTAGCGAGTTTACA
GTTAAGCTATTTAAGCAAGAAGATGCATACAAGATCTTCGAAAGATGTTGA


>TTHERM_00127000(gene)
AATTTATTAAATATACATAAAAAAAGTAATTGAATATACATAGGTATATGAATCATTCCT
AACCCTTAGAAAATACTGGTCCTCAGATCAAGAAGCTCCCATAAGAGCTTATCGATAAGA
TTGCAGCTGGTGAAGTAGTACAACGTCCATCTGCAGCTGTTAAGGAGCTTATTGAGAACT
GTCTTGATGCTGGATCAAGTGAAATTTCAGTAGGGTTAGTATAAGGAGGGTTAAAGTAGC
TTATTGTAGAAGATAATGGTTCTGGAATTCACAAAGACGATTTTCCACTTCTCTGCGAAA
GGTTTGCTACCTCTAAGATAAATGAGTTTAATGACCTTTAGAGTTTAGTTTCATTTGGCT
TTAGAGGAGAAGCGTTAGCCTCTATTTCTTTTGTCTCCAACTTGAAAATCACATCTCGAA
AACCTAATTCTGACCTAGGATATAAAGCTAGTTTCAAAAACGGTGTTATGCTTGGTGAAG
AGCCTGAAGCAGTGAACTGTACTGAAGGGACTACAGTAGATGTCTAGGATTTATTTTTTA
ACTATGATGCAAGGAGAAAAAGTTTAAATGTTAACGAAGAAAAAAAAAGAGTACTCAAAT
TGATCGGACAATTTGCTATGCATCATGCTAAATTGAGATTTAAATTTAAAAGTGATAACC
AAATTCAATTCTCATCTCACAGTGTGCTTGGCTCTACAGAATTGCAAAGAAGAGAATAAA
TTATGTAGCAAATTACTAAGATTGCAGATAAAAGCTTTACTTCATGTGAAAGTGAGTCGA
CAGAATATTAAGTTAAATTTAAAGGAACTTTTTCCAACATTGGAGCTACTAAAAAATACA
AAGAAATCACTCTCTTTATAAATAATCGTTTGGTTGAATGTGAATCTATCAAAAAAGCAG
TAGAACGCTCTTACCAGTCTTGTTATTAAAGTATTCATGAAGAAGAAGGTGGATATTTTT
GCTACTTGAGCTTAGAAATGAATCCAAAGAACTTGGATCCTAATGTTCACCCAACAAAAA
AAGAAGTCAAATTCTTATTTGAGTACGAAATAGCAAAAGAAATTGAATCATGGATTTTCG
AAAATTTGAAAAATTGTGGAGTTATCAAACAACTTTCAGCAAATATTTCATAAAGAACAT
CTTCATTTGAAACTTCAAATGTGAAAAGAAGTAGCTCAAGTCAATTATATTTTGGTTCTT
AGAGCAATTTATCTAAGCAAAATTCTGATTACTATCAACCCACCAAGCAAATTCGTGTAG
ATCCCAGAGATTAGAAAATTACTAGATTCTTTTCAGTAGAAAGCTCTGAAGATGGAAATA
ACAATTCAAATCAAAAAAATTATCAAAGTATTAATTATATTGAAGAGCAGAAAGAAGAAC
ATCTAAACAGTCAAGATGATATTGCTGAAGAACCTGTTGATATGATTAAAAAGAAAAAGA
TGCTCAATGAAGAAAGAAATTAAACTTCAATCAGTAATATAGGAAGCTCTGACTAATTAG
ATGCTAATAATGCTCGTTCAAGTGTCATCGATAGGGCAAATTCTTAAGTTAATGACCCAC
GTATTTAAGTATAATAATAGTTATTGTCTTTAAGGAATCAAGATATCCATGATACAACAA
GTTCTTTCTTTAAAAATCTTACGTATGTTGGCTGTATTTCTTCTAATCACTTTCTAGCTC
AATTTAGAGATGATCTCTACCTTATAAACTCTATTCCATTATGTTAAGAAATATTTAAAT
TTGAAATTCTGAGAAACTTTGGATAGATTAAGCCTGTAGAGCTAAATTAAGCAATAGGTT
TGAAGGATATTTTAGAGTATTTTTTATTAAATTTTGATGAGATACCGAATGAGAAAAAGG
AGTTCCATCTGTCAAATATGGATACTTACATCGAGTAATTTGGCTTATTGAGTGACTTTT
TAAGAGACTCCGTAGGCATAGTCATCAAAGATTAAAAGCTCTTGGCTTTCCCTAATTTAT
TTAATTTATTTGAAAATGATAATAACTTTAAAGATATCTCATACATTCTGTTGAGAATAA
TCACCAAAGTTAATTTTAGCGAAATACTCTAATCAGGTATGGGCTTAGCAAACGAATTAT
CATTCTACTTTGCTTGGCAATTAGAAAAATCGTTTAAAAATTAATTGTAAAGACAGCATT
TCTAGGAAACGCAAAAGCAGAAATGGGACGATTTCTTTGAATAAAAAATGCTCCCAATGA
TTAAAAAAAAACTTTCACTCCCTAAATTAGATATTAGCGAGTTTACAGTTAAGCTATTTA
AGCAAGAAGATGCATACAAGATCTTCGAAAGATGTTGAGTTATTCATTGTATTGATAATA
ACTTAATAATATTTCTATTTTACCAAATAGAACTAAAAACAATTAACAAAAATAATCAAT
TTCTTTATTAATTAAACAAAAACAAACATTAAATTTTATTTGATCTAATTATTATATTCT
CAGAAACATCCTCTACTCAATTTACTCATAAATAAAACCAGTTACTCTTAAATTTCTACT
GATTAGGTTTCTTGAAAACATTCATCTAAACAGCAGAGTTGTAAAAAATGGCAAAAACAA
CTAAATTAGCCTATCTTTTTAAAGAATACCAAGGGTAAAAGCTTTATTCACATTGTATGA
GTTGGATGGCAGAAAAAATCAAACAACAAACAAACAAACAAAAACACAAAGAAGCAAAAA
ATTAATATTCAAACATTAAAAAAAACAACAAATCAATACTAAATGTGTTGCTAGAATTCT
AAAAAAGTAAATTAACTTGACAAACAAACAAACAATTAAAAAAA


>TTHERM_00127000(protein)
MNHSQPLENTGPQIKKLPQELIDKIAAGEVVQRPSAAVKELIENCLDAGSSEISVGLVQG
GLKQLIVEDNGSGIHKDDFPLLCERFATSKINEFNDLQSLVSFGFRGEALASISFVSNLK
ITSRKPNSDLGYKASFKNGVMLGEEPEAVNCTEGTTVDVQDLFFNYDARRKSLNVNEEKK
RVLKLIGQFAMHHAKLRFKFKSDNQIQFSSHSVLGSTELQRREQIMQQITKIADKSFTSC
ESESTEYQVKFKGTFSNIGATKKYKEITLFINNRLVECESIKKAVERSYQSCYQSIHEEE
GGYFCYLSLEMNPKNLDPNVHPTKKEVKFLFEYEIAKEIESWIFENLKNCGVIKQLSANI
SQRTSSFETSNVKRSSSSQLYFGSQSNLSKQNSDYYQPTKQIRVDPRDQKITRFFSVESS
EDGNNNSNQKNYQSINYIEEQKEEHLNSQDDIAEEPVDMIKKKKMLNEERNQTSISNIGS
SDQLDANNARSSVIDRANSQVNDPRIQVQQQLLSLRNQDIHDTTSSFFKNLTYVGCISSN
HFLAQFRDDLYLINSIPLCQEIFKFEILRNFGQIKPVELNQAIGLKDILEYFLLNFDEIP
NEKKEFHLSNMDTYIEQFGLLSDFLRDSVGIVIKDQKLLAFPNLFNLFENDNNFKDISYI
LLRIITKVNFSEILQSGMGLANELSFYFAWQLEKSFKNQLQRQHFQETQKQKWDDFFEQK
MLPMIKKKLSLPKLDISEFTVKLFKQEDAYKIFERC