Identifiers and Description

Gene Model Identifier

TTHERM_00129830

Standard Name

HEX1 (beta-HEXosaminidase )

Aliases

PreTt09534 | 9.m00555 | 3699.m00263

Description

HEX1 glycosyl hydrolase family 20 beta-N-acetylhexosaminidase family protein; Lysosomal beta-hexosaminidase; synthesized as a precursor that is processed into several mature glycosylated isozymes; isozymes are secreted during both growth and starvation; a fraction remains covalently bound to the plasma membrane; Beta-hexosaminidase

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Domains

  • ( PF00728 ) Glycosyl hydrolase family 20, catalytic domain
  • ( PF14845 ) beta-acetyl hexosaminidase like

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:8022306: Bencsáth M, Darvas Z, Csaba G (1994) Secretory response of Tetrahymena to insulin: the influence of electric pulses. Microbios 78(314):27-33
  2. Ref:8482338: Kiy T, Vosskühler C, Rasmussen L, Tiedtke A (1993) Three pools of lysosomal enzymes in Tetrahymena thermophila. Experimental cell research 205(2):286-92
  3. Ref:8366828: Bencsáth M, Darvas Z, Csaba G (1993) The effect of an electric field on the release of hexosaminidase in Tetrahymena. Microbios 74(301):227-32
  4. Ref:1386323: Rasmussen L, Florin-Christensen M, Florin-Christensen J, Kiy T, Tiedtke A (1992) Differential increase in activity of acid phosphatase induced by phosphate starvation in Tetrahymena. Experimental cell research 201(2):522-5
  5. Ref:1368701: Kiy T, Tiedtke A (1991) Lysosomal enzymes produced by immobilized Tetrahymena thermophila. Applied microbiology and biotechnology 35(1):14-8
  6. Ref:2971351: Hünseler P, Tiedtke A, von Figura K (1988) Biosynthesis of secreted beta-hexosaminidase in Tetrahymena thermophila. A comparison of the wild type with a secretory mutant. The Biochemical journal 252(3):837-42
  7. Ref:2954837: Banno Y, Sasaki N, Nozawa Y (1987) Secretion heterogeneity of lysosomal enzymes in Tetrahymena pyriformis. Experimental cell research 170(2):259-68
  8. Ref:43892: Vick GW, Blum JJ (1979) Secretion of hexosaminidase isozymes by Tetrahymena. The Journal of protozoology 26(3):510-8
  9. Ref:17821280: Harrison JA, Fowler EH (1945) AN ANTIGEN-ANTIBODY REACTION WITH TETRAHYMENA WHICH RESULTS IN DYSTOMY. Science (New York, N.Y.) 102(2638):65-6

Sequences 

>TTHERM_00129830(coding)
ATGCAAAAGATACTTTTAATTACTTTCCTTCTTGGAATAGCTCTCGCTCAAATTACTCCT
GGCGTTGACCCTATTTCAGCTAAGGTTATGCCTAAACCTAAGAATTACACTTATGGAGAT
TTGAGCTTACTTGTCACTGATCCTTGCGGAATCTCTTACAGACCTTCTGTTGGGTCAGGA
AAAGTACCCAACCATGTCTATCAAATTATTGGATTCTACACTTTGAATATTTTCAATTCT
AACGAAAACTCTTGTGCTATGTAAAGAGAATTGTATAAGAATGAAACAACCATTGAAAAG
ATGCGTAGATTACAACATTCCTAAAATATAGTCTTCGATATTTTTATCTAAGACGCTGCT
TTGGCCACTGCAGACACACTCGAAGACGAATATTATGATTTATAAATTTATAATACCACA
TATTGGAAATTGACTGCTAACAAATATGTTGGTTTACTCCGTGGTTTAGAAACTTACTCT
CAATTATTCACTTAAGACGAAGACACTGAAGATTGGTATTTGAATAACATCCCTATTTCT
ATTCAAGATTAACCTGACTACATCTACAGAGGTCTTATGATAGATTCAGCCAGACATTTC
TTATCAGTTGAAACTATTTTAAAAACTATTGATTCTATGTTATTCAACAAGTTGAATGTT
CTCCATTGGCACATCACTGATACTGAATCCTTCCCCTTCCCTCTTAAATCATTCCCTAAT
ATTACTAAATATGGAGCCTACTCTAAGAAGAAACAATACAGCTTCGAAGACATTTAATAC
ATTGTAGACTAAGCTCTCAACAAGGGTATTTAAGTTATTCCTGAAGTCGATTCTCCAGGA
CACGCTTTTTCATGGGCTAGATCTCCTTAATTCTCTAGTATTGGTCTATTATGTGATTAA
TATAATGGATAGTTAGACCCAACACTAAATTTAACTTACACTGCTGTTAAGGGTATTATG
GAAGATATGAATACTTAATTCTACACTGCTAAGTATGTTCATTTTGGTGGTGATGAAGTT
GAAGAATAATGCTGGAATAAACGCCCTGAAATTAAGGAATTCATGAATTAAAATAACATC
TCTACATATACTGATTTGTAGAATTATTACAGAAAGAACTAAGTTAACATTTGGAAATCA
ATTAATGCTACTAAGCCTGCTATTTTCTGGGCAGATTCAAATACTTTGAAATATGGTCCT
GATGATATTATTCAATGGTGGGGATCTACTCATGATTTTTCTTCAATCAAAGATCTTCCT
AACAAAATAATTTTATCTTTCTATGATAATACTTATTTGGATGTTGGTGAGGGAAATAGA
TATGGTGGAAGTTATGGCAGCATGTATAACTGGGATGTCTTAAACTCTTTCAATCCTAGA
GTTCCTGGAATTAAGGGTGAAATTCTTGGTGGCGAAACATGCTTATGGAGTGAAATGAAT
GATGATTCTACTTAATTCTAAAGACTTTGGACAAGAAATAGTGCATTTGCTGAAAGACTT
TGGAACACTGACGCTGCTAATAATGAAACTTACAAAACTAGAGCTTTAGTTAGCAGAATG
GTCTTTATGCAACACCGTTTAACTGCTAGAGGAATCCCTGCTTCTCCTGTAACAGTTGGT
ATTTGTGAATAAAACCTTTCTCTCTGCTACAATTGA



>TTHERM_00129830(gene)
CCCTTAATAATTTTAATATATATATTAAAAATACACTGATTTAATTACATAATAAATTAG
CAGTAATAAAAAATTCTAAATATATTGATTGTAGCTATGCAAAAGATACTTTTAATTACT
TTCCTTCTTGGAATAGCTCTCGCTCAAATTACTCCTGGCGTTGACCCTATTTCAGCTAAG
GTTATGCCTAAACCTAAGAATTACACTTATGGAGATTTGAGCTTACTTGTCACTGATCCT
TGCGGAATCTCTTACAGACCTTCTGTTGGGTCAGGAAAAGTACCCAACCATGTCTATCAA
ATTATTGGATTCTACACTTTGAATATTTTCAATTCTAACGAAAACTCTTGTGCTATGTAA
AGAGAATTGTATAAGAATGAAACAACCATTGAAAAGATGCGTAGATTACAACATTCCTAA
AATATAGTCTTCGATATTTTTATCTAAGACGCTGCTTTGGCCACTGCAGACACACTCGAA
GACGAATATTATGATTTATAAATTTATAATACCACATATTGGAAATTGACTGCTAACAAA
TATGTTGGTTTACTCCGTGGTTTAGAAACTTACTCTCAATTATTCACTTAAGACGAAGAC
ACTGAAGATTGGTATTTGAATAACATCCCTATTTCTATTCAAGATTAACCTGACTACATC
TACAGAGGTCTTATGATAGATTCAGCCAGACATTTCTTATCAGTTGAAACTATTTTAAAA
ACTATTGATTCTATGTTATTCAACAAGTTGAATGTTCTCCATTGGCACATCACTGATACT
GAATCCTTCCCCTTCCCTCTTAAATCATTCCCTAATATTACTAAATATGGAGCCTACTCT
AAGAAGAAACAATACAGCTTCGAAGACATTTAATACATTGTAGACTAAGCTCTCAACAAG
GGTATTTAAGTTATTCCTGAAGTCGATTCTCCAGGACACGCTTTTTCATGGGCTAGATCT
CCTTAATTCTCTAGTATTGGTCTATTATGTGATTAATATAATGGATAGTTAGACCCAACA
CTAAATTTAACTTACACTGCTGTTAAGGGTATTATGGAAGATATGAATACTTAATTCTAC
ACTGCTAAGTATGTTCATTTTGGTGGTGATGAAGTTGAAGAATAATGCTGGAATAAACGC
CCTGAAATTAAGGAATTCATGAATTAAAATAACATCTCTACATATACTGATTTGTAGAAT
TATTACAGAAAGAACTAAGTTAACATTTGGAAATCAATTAATGCTACTAAGCCTGCTATT
TTCTGGGCAGATTCAAATACTTTGAAATATGGTCCTGATGATATTATTCAATGGTGGGGA
TCTACTCATGATTTTTCTTCAATCAAAGATCTTCCTAACAAAATAATTTTATCTTTCTAT
GATAATACTTATTTGGATGTTGGTGAGGGAAATAGATATGGTGGAAGTTATGGCAGCATG
TATAACTGGGATGTCTTAAACTCTTTCAATCCTAGAGTTCCTGGAATTAAGGGTGAAATT
CTTGGTGGCGAAACATGCTTATGGAGTGAAATGAATGATGATTCTACTTAATTCTAAAGA
CTTTGGACAAGAAATAGTGCATTTGCTGAAAGACTTTGGAACACTGACGCTGCTAATAAT
GAAACTTACAAAACTAGAGCTTTAGTTAGCAGAATGGTCTTTATGCAACACCGTTTAACT
GCTAGAGGAATCCCTGCTTCTCCTGTAACAGTTGGTATTTGTGAATAAAACCTTTCTCTC
TGCTACAATTGATTCTAAATATAAAAATTAAATAAATATTTTAAGAAATATTTTTAAGAA
TATTTTAGTATAAAAACTGTATTTTAATTGATAAAAAAAATATAAATATTATTATTAATT
GAATTTTAGCTATTAATTTTATTAATATCTGAAACATATCTTAATTTAATTTTACTAAGT
GTTCATCCCTTTTTTAATTTAGCATAGAGATGGTCACATATTTTATTTTTTTAAAAATGT
ATGTACTTTTTTAAATTAGAAGTTTTTAAAAAATTATGGTATTTAATTCTTTAATTTATT
TCAAATATGAGTTTAAAA



>TTHERM_00129830(protein)
MQKILLITFLLGIALAQITPGVDPISAKVMPKPKNYTYGDLSLLVTDPCGISYRPSVGSG
KVPNHVYQIIGFYTLNIFNSNENSCAMQRELYKNETTIEKMRRLQHSQNIVFDIFIQDAA
LATADTLEDEYYDLQIYNTTYWKLTANKYVGLLRGLETYSQLFTQDEDTEDWYLNNIPIS
IQDQPDYIYRGLMIDSARHFLSVETILKTIDSMLFNKLNVLHWHITDTESFPFPLKSFPN
ITKYGAYSKKKQYSFEDIQYIVDQALNKGIQVIPEVDSPGHAFSWARSPQFSSIGLLCDQ
YNGQLDPTLNLTYTAVKGIMEDMNTQFYTAKYVHFGGDEVEEQCWNKRPEIKEFMNQNNI
STYTDLQNYYRKNQVNIWKSINATKPAIFWADSNTLKYGPDDIIQWWGSTHDFSSIKDLP
NKIILSFYDNTYLDVGEGNRYGGSYGSMYNWDVLNSFNPRVPGIKGEILGGETCLWSEMN
DDSTQFQRLWTRNSAFAERLWNTDAANNETYKTRALVSRMVFMQHRLTARGIPASPVTVG
ICEQNLSLCYN