Identifiers and Description

Gene Model Identifier

TTHERM_00133690

Standard Name

FRS1 (Phenylalanyl(F)-tRNA Synthetase 1)

Aliases

PreTt24292 | 10.m00341 | 3698.m00063

Description

FRS1 phenylalanyl-tRNA synthetase alpha chain putative; Phenylalanyl-tRNA synthetase; alpha subunit family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IEA) | GO:0005737

Molecular Function

• ATP binding (IEA) | GO:0005524
• phenylalanine-tRNA ligase activity (IEA) | GO:0004826
• tRNA binding (IEA) | GO:0000049

Biological Process

• phenylalanyl-tRNA aminoacylation (IEA) | GO:0006432

Domains

• ( PF00152 ) tRNA synthetases class II (D, K and N)
• ( PF01409 ) tRNA synthetases class II core domain (F)
• ( PF07377 ) Protein of unknown function (DUF1493)
• ( TIGR00468 ) phenylalanyl-tRNA synthetase, alpha subunit
• ( TIGR00470 ) O-phosphoseryl-tRNA(Cys) synthetase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_05732.1	9.997093137033517e-262
	Description: phenylalanyl-tRNA synthetase, alpha subunit protein (513 aa)
Tetrahymena borealis	EI9_05941.1	9.997093137033517e-262
	Description: hypothetical protein (239 aa)
Oxytricha	Contig1385.1.g55	3.000071119766155e-172
	Description: tRNA synthetases class II core domain (F)
WormBase	WBGene00001497	9.995404496431436e-166
	Description: locus:fars-1 status:Confirmed UniProt:Q86B36 protein_id:CCD67615.1
WormBase	WBGene00020932	9.995404496431436e-166
	Description: locus:dhod-1 status:Confirmed UniProt:O01815 protein_id:CCD68985.1
SGD	YFL022C	4.001878793042739e-150
	Description: FRS2 Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
DictyBase	DDB_G0287141	5.997984985848154e-146
	Description: phesA on chromosome: 4 position 5374001 to 5375464
Stentor Coeruleus	SteCoe_30854	2.7086952666810816e-76
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00133690(coding)
ATGGAAAAGAATTACACTTAATTAATTTTAACTGAATTAGAGTAAAATGGTGAAATCCCT
GATACTCTATTATTGGCAAAGAAATTTGAAATTGAACATCAAGAATTAGTTGGTTATTTA
AATTCTTTGCTTTTAGAGAACTACATTACTTAAGAAGTTAAGGAAATTTAAAGATGGGTA
CTTTTATAAGAAGGTTTAGATAATGTTACTAATGGCACTCCCGAATTCAGAGTGTTCTAG
GGTATCCCTGCTGAAGGTATTTCAAAGAATGATTTAGAAGCTAAATTTGATCCCAATGTT
TTCAAGTTCGGTTTATAAAATGGTATGAAAAAGAAGTGGTTCAAGATTAAGGACGGTCTT
ATTCAAAAAGAAGTAGCTGAAGTAGTCGATGAAGATGCTGTTCTTTTAAAAAGAATTGAA
TCTAACAGCAATTTGGAAGATATTAAAAAGGACGTTTTCGATAATCTTAAGAAGAGAAAG
ATTATTTCTTAGGAAGTTATCAAATATTTCAAAATTAATAAAGGTGCTGAATTCAAGCCC
ATTTATGTTGAACTTGAATCTGATTTAACTTATGATATGGTTAAGAACTACGATGATTTT
GTCAAGAATGAAGATGGAACAATTAAATCAAATACTGAACTCGCTAAATAATTCAAAAAA
TATAATTGGAATTCTGTTGGTAAAGATATAAAAACTGGTAACTTGCATCCTTTGATGAAA
GTCAGAAAATAATTCAGAGAAGTTCTTATTGAAATGGGATTCGAAGAAATGGCTACCAAC
CAATATGTTGAAAGTGGTTTCTGGAACTTCGATGCCCTTTTCTAACCTTAATAACATCCT
GCCAGAGATGCTCACGATACTTTCTTCATTAGAGAACCTGCTCACAGCAAGAATTTAGAT
CCTGAATACTGGGAAAGAGTTAAGAAAACTCACGAAGTAGGTGGTTATGGATCTATTGGT
TATCGTTATGATTGGAGTTATGATGAAGCCAAAAAGAACATCTTCCGTACTCACACAACT
GCTGTTTCATCTAAAATGTTAAGACAAATTGCCATCGAATATGCTAAGGACGGCGTTTTC
AAACCTAGAAAATTCTTCTCTATTGATAGAGTCTTCAGAAATGAAAGCTTAGATGCTACT
CACTTGGCTGAATTCCATTAAATTGAAGGTGTTATCGCTGATAAGAATGTTGGTCTTGGT
GAACTACTTGGAGTTATTACTGAATTCTTTGCTAAAATAGGTATTACTGGCTTGAAGTTT
AAGCCCACATATAACCCATACACAGAACCATCCTTGGAAATTCATGGTTTCCATCCTGGT
TTGAATAAAGTCATTGAATTAGGTAACAGTGGTGTTTTCAGACCTGAAATGTTACGTCCC
ATGGGATTACCAGAAGATATTTAAGTTTTAGGTTGGGGTCTTGGTTTAGAAAGACCTACA
ATGATATAATATAAATTCAAAAATATCAGAGATCTTCTTGGTTACGGTGTAGATATGAAA
CTCCTTAAGGAAAATCCTATTTGCTGTTTCAAGAATTGA

>TTHERM_00133690(gene)
ATGGAAAAGAATTACACTTAATTAATTTTAACTGAATTAGAGTAAAATGGTGAAATCCCT
GATACTCTATTATTGGCAAAGAAATTTGAAATTGAACATCAAGAATTAGTTGGTTATTTA
AATTCTTTGCTTTTAGAGAACTACATTACTTAAGAAGTTAAGGAAATTTAAAGATGGGTA
CTTTTATAAGAAGGTTTAGATAATGTTACTAATGGCACTCCCGAATTCAGAGTGTTCTAG
GGTATCCCTGCTGAAGGTAAATTTATTTTATCTTTATTTGAATTCATACCTTAAAACAGT
TTACAGCAATTTCTAAAAAATAGTTTTACAGCTTAGATTTATTATAAAATTTGGCACATT
TCAAAAAATATTTTTTAAATTTGTATGAATTTAAAGCTCAATAAGCAAACAAATAAATGA
TTTATTTTAACTAATGATAAATTTAGGTATTTCAAAGAATGATTTAGAAGCTAAATTTGA
TCCCAATGTTTTCAAGTTCGGTTTATAAAATGGTATGAAAAAGAAGTGGTTCAAGATTAA
GGACGGTCTTATTCAAAAAGAAGTAGCTGAAGTAGTCGATGAAGATGCTGTTCTTTTAAA
AAGAATTGAATCTAACAGCAATTTGGAAGATATTAAAAAGGACGTTTTCGATAATCTTAA
GAAGAGAAAGATTATTTCTTAGGAAGTTATCAAATATTTCAAAATTAATAAAGGTGCTGA
ATTCAAGCCCATTTATGTTGAACTTGAATCTGATTTAACTTATGATATGGTTAAGAACTA
CGATGATTTTGTCAAGAATGAAGATGGAACAATTAAATCAAATACTGAACTCGCTAAATA
ATTCAAAAAATATAATTGGAATTCTGTTGGTAAAGATATGTAAATAACCTATTTGAATAT
TTTTATGTTAATGCTGCTTAAGATATTATATTTTTATTTTTAAATAAACGACTTTTATAC
TAAAAAATACGATTTATAAAAATAGAAAAACTGGTAACTTGCATCCTTTGATGAAAGTCA
GAAAATAATTCAGAGAAGTTCTTATTGAAATGGGATTCGAAGAAATGGCTACCAACCAAT
ATGTTGAAAGTGGTTTCTGGAACTTCGATGCCCTTTTCTAACCTTAATAACATCCTGCCA
GAGATGCTCACGATACTTTCTTCATTAGAGAACCTGCTCACAGCAAGAATTTAGATCCTG
AATACTGGGAAAGAGTTAAGAAAACTCACGAAGTAGGTGGTTATGGATCTATTGGTTATC
GTTATGATTGGAGTTATGATGAAGCCAAAAAGAACATCTTCCGTACTCACACAACTGCTG
TAATTTACTGAATTTAACCTTTAAAAATAATTAATTAATAAATAGCTAGAAAAAATAAAT
AATTAGCATAAAAAATATTTAGAATATTATCAAAAAAAATTAGCTAAGCAAATATTATTG
AAATAATAATTAGGTTTCATCTAAAATGTTAAGACAAATTGCCATCGAATATGCTAAGGA
CGGCGTTTTCAAACCTAGAAAATTCTTCTCTATTGATAGAGTCTTCAGAAATGAAAGCTT
AGATGCTACTCACTTGGCTGAATTCCATTAAATTGAAGGTGTTATCGCTGATAAGAATGT
TGGTCTTGGTGAACTACTTGGAGTTATTACTGAATTCTTTGCTAAAATAGGTAATATTAT
TTTAGCTTTTATAAATAAATATTCTATTTTTTAAATTAAATCAATAAATTAAAGGTATTA
CTGGCTTGAAGTTTAAGCCCACATATAACCCATACACAGAACCATCCTTGGAAATTCATG
GTTTCCATCCTGGTTTGAATAAAGTCATTGAATTAGGTAACAGTGGTGTTTTCAGACCTG
AAATGTTACGTCCCATGGGATTACCAGAAGATATTTAAGTTTTAGGTTGGGGTCTTGGTT
TAGAAAGACCTACAATGATATAATATAAATTCAAAAATATCAGAGATCTTCTTGGTTACG
GTGTAGATATGAAACTCCTTAAGGAAAATCCTATTTGCTGTTTCAAGAATTGA

>TTHERM_00133690(protein)
MEKNYTQLILTELEQNGEIPDTLLLAKKFEIEHQELVGYLNSLLLENYITQEVKEIQRWV
LLQEGLDNVTNGTPEFRVFQGIPAEGISKNDLEAKFDPNVFKFGLQNGMKKKWFKIKDGL
IQKEVAEVVDEDAVLLKRIESNSNLEDIKKDVFDNLKKRKIISQEVIKYFKINKGAEFKP
IYVELESDLTYDMVKNYDDFVKNEDGTIKSNTELAKQFKKYNWNSVGKDIKTGNLHPLMK
VRKQFREVLIEMGFEEMATNQYVESGFWNFDALFQPQQHPARDAHDTFFIREPAHSKNLD
PEYWERVKKTHEVGGYGSIGYRYDWSYDEAKKNIFRTHTTAVSSKMLRQIAIEYAKDGVF
KPRKFFSIDRVFRNESLDATHLAEFHQIEGVIADKNVGLGELLGVITEFFAKIGITGLKF
KPTYNPYTEPSLEIHGFHPGLNKVIELGNSGVFRPEMLRPMGLPEDIQVLGWGLGLERPT
MIQYKFKNIRDLLGYGVDMKLLKENPICCFKN