Identifiers and Description

Gene Model Identifier

TTHERM_00136470

Standard Name

AMT5 (Adenine MethylTransferase (AMT) 5 targeting position N-six of Adenine)

Aliases

PreTt24372 | 10.m00421 | 3698.m00140 | MTA3

Description

MT-A70 family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• methyltransferase activity (IEA) | GO:0008168

Biological Process

• nucleobase-containing compound metabolic process (IEA) | GO:0006139

Domains

• ( PF00569 ) Zinc finger, ZZ type
• ( PF01555 ) DNA methylase
• ( PF01754 ) A20-like zinc finger
• ( PF05063 ) MT-A70

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_05814.1	9.997093137033517e-262
	Description: MT-A70 family protein (503 aa)
Tetrahymena borealis	EI9_06116.1	9.997093137033517e-262
	Description: hypothetical protein (577 aa)
Oxytricha	Contig17486.0.g100	9.9981864321491e-40
	Description: MT-A70
Stentor Coeruleus	SteCoe_23497	7.781132241133797e-20
	Description: None
SGD	YGL192W	3.998609120989657e-17
	Description: IME4 Probable mRNA N6-adenosine methyltransferase required for entry into meiosis; transcribed in diploid cells; haploids repress IME4 transcription via production of antisense IME4 transcripts; antisense transcription is repressed in diploids

General Information

No Data fetched for General Information

Associated Literature

1. Ref:31722409: Wang Y, Sheng Y, Liu Y, Zhang W, Cheng T, Duan L, Pan B, Qiao Y, Liu Y, Gao S (2019) A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N6-adenine methylation at the ApT dinucleotides as an epigenetic mark associated with transcription. Nucleic acids research 47(22):11771-11789

Sequences

>TTHERM_00136470(coding)
ATGAAAAGGGATTAACAAGAATCTGAAGAAGAGAGCGAGGAAAGTGGGGATGACTCTGAT
TCTGTCGAGGTTTAGAGGGCAACAAATGTTAGGGCTAAATCATATCATGATTCAAATAAT
GTTATTTTAGGAAAAAGATAAAGGAGAGAATCAACCAAACATGCCAAAGATGACTTGATA
GGATTTAAGGAGAAAAAAAAGAAGCGCGGTAGAAAAGCTAAAAAGAAAAAACCTTTGCCA
ATAAAAAAGAAGGGTCGCAAGAAAAAGAAAGTCTCAAAAAAAAGTTAAAAAAATGGATAG
TTGAGGGGAAATGGTGAAAAAAGAGAAAAAAAAGAGAAAGGAGAGAAAGTTATTAAAGAA
AGATCTAAGGTAAAGGTAGAGGATGAAGATGATGAGTTTAGACATCAAAATCCTAACTTG
ATTCATCTCTCAAAGCTAAATAAAATATTTGTTTTGCACAGCAGTGAAATAAGAGCAAAC
AAAAAAGACAAAAAAAAGCTATTTCAAAATACCTTACTAGCTAAAACACCAGAAGAAAAA
AGAACCTCACAATCTATCATCGAATGTGATTTAAGATACTTTGATTTTACTTATTTGACA
AACATATTTGACTCGTTTGATGTTGTAATGATTGCTCCACCATTTGATGCAATATCGATT
TAAGAAGTATTTGAACTAAAAGTGGAGTTGATCTCTAAGCAAGGATTTCTTTTTTTCTGG
GCAAAAGATGTTCCAACAGCTACTTCATATGAAATAATGTCTAAATGGGGATATGATGTT
ATTGATCAAATTATTTGGGTGAAAATCGATAAAAATGAAGGGAAAATGATTTTAGAAGAC
AAGCCAGACAAATATTTTTATAATTCAAATGAAATGTGCTTAATAGGTGTCAAAAAGCAC
CCTTCCTCAAAGGGAGTTGAGTATCAATCAAAGGTATCAAACAATATCATAGTTTCTCAT
CAACCATAGAATTAATCTTGTCCAGATTAAATATACGATATTATTGATTTGATGATGCCA
GGAAGCAAAAAAATAGAACTTTTTACTAAACAGAAAGTAATCAGAGGAGGCTGGTTTGGG
TTAGAGCATAAGTTTTAACCAGAGATAAACTAAAGTAAAAATTTAAATCAACAAATCAAT
ACTAAAGAATCAGATAAAGCAGCTCATTTTGATCATACTAAAGTCTAAGATATTCAAGCT
ATAAAAAATAATTAAATTCCTATTTTCAATTAGTAGCAATGCCTTAAATGTGAGATGAAA
CCAATCGTTGGGCTGTATTTTTCTTGTGAAACATGCAAGATAGATACTCAGAACTCTTTC
TCTATATGCTAAGATTGCTTCTTTAATACATCTCCAAAAGAATTATTTATTGGAAATCAT
AACGAAAACCATAAATTAGAAATTGTTCACGAAATACCTCAATAAACTTATAAATAAAAA
CTTAAATGCACGAATATATCTTGTTAGAAAGATTTATCATACTCTTTAGTACACAAATGC
TTAACCTGTTTTGAATTGTACTTATGTGAAAAGTGCTATGCAAACCAAAATAAAGTTAAG
CTTCCAAATACCCTCAAGGATTCACATTAATACTACCATGATTTTTTTATGATTAAATGA

>TTHERM_00136470(gene)
ATGGTAATATCCAATTTATTTATCGATTTGACTTAATTATAAACTCTATTCAAAAAGAAA
AGGGATTAACAAGAATCTGAAGAAGAGAGCGAGGAAAGTGGGGATGACTCTGATTCTGTC
GAGGTTTAGAGGGCAACAAATGTTAGGGCTAAATCATATCATGATTCAAATAATGTTATT
TTAGGAAAAAGATAAAGGAGAGAATCAACCAAACATGCCAAAGGTAAGTTCATCTCTAAA
TTAACAATTATATAATTTCTTTAATGACTTAGAATGACAATCATTTTAATAATTTAAAAA
ATAAGATGACTTGATAGGATTTAAGGAGAAAAAAAAGAAGCGCGGTAGAAAAGCTAAAAA
GAAAAAACCTTTGCCAATAGTAAATAATTTAGATTTAAATATTTAAAAACAAACCTTTCT
TAATTTAATTTATGCATATATTATAAATATGATTTTATAAAAACAATGTAAAATACTTTC
AAATTTAAATTAAAAATCACACTAAATTGATAATGATTTTATTAGTAGAAAAAGAAGGGT
CGCAAGAAAAAGAAAGTCTCAAAAAAAAGTTAAAAAAATGGATAGTTGAGGGGAAATGGT
GAAAAAAGAGAAAAAAAAGAGAAAGGAGAGAAAGTTATTAAAGAAAGATCTAAGGTAAAG
GTAGAGGATGAAGATGATGAGTTTAGACATCAAAATCCTAACTTGATTCATCTCTCAAAG
CTAAATAAAATATTTGTTTTGCACAGCAGTGAAATAAGAGCAAACAAAAAAGACAAAAAA
AAGCTATTTCAAAATACCTTACTAGCTAAAACACCAGAAGAAAAAAGAACCTCACAATCT
ATCATCGAATGTGATTTAAGATACTTTGATTTTACTTATTTGACAAACATATTTGACTCG
TTTGATGGTAATTGAATATTCAATTTAACAATATATTTATTTTTAATTTTATTTATTCAA
AAAAATTTATTAATTAAAAAATTTTATTTTATTAAAATAAAATCAAAACTAATTTAATTA
ATTTTAACGCTTTTAAATTGTTAAAAATTTAGTTGTAATGATTGCTCCACCATTTGATGC
AATATCGATTTAAGAAGTATTTGAACTAAAAGTGGAGTTGATCTCTAAGCAAGGATTTCT
TTTTTTCTGGGCAAAAGATGTTCCAACAGCTACTTCATATGAAATAATGTCTAAATGGGG
ATATGATGTTATTGATCAAATTATTTGGGTGAAAATCGATAAAGTAATTTAACTAATTAC
TAACATTTTGTTTTATTTTATTTTATTATTAGAATGAAGGGAAAATGATTTTAGAAGACA
AGCCAGACAAATATTTTTATAATTCAAATGAAATGTGCTTAATAGGTGTCAAAAAGCACC
CTTCCTCAAAGGGAGTTGAGTATCAATCAAAGGTATCAAACAATATCATAGTTTCTCATC
AACCATAGAATTAATCTTGTCCAGATTAAATATACGATATTATTGATTTGATGATGCCAG
GAAGCAAAAAAATAGAACTTTTTACTAAACAGAAAGTAATCAGAGGAGGCTGGTTTGGGT
TAGAGCATAAGTTTTAACCAGAGATAAACTAAAGTAAAAATTTAAATCAACAAATCAATA
CTAAAGAATCAGATAAAGCAGCTCATTTTGATCATACTAAAGTCTAAGATATTCAAGCTA
TAAAAAATAATTAAATTCCTATTTTCAATTAGTAGCAATGCCTTAAATGTGAGATGAAAC
CAATCGTTGGGCTGTATTTTTCTTGTGAAACATGCAAGATAGATACTCAGAACTCTTTCT
CTATATGTAATTTTTTCCTAAATTAATATTTTTAAAGTTATTTTTTATTTTAATTATAGG
CTAAGATTGCTTCTTTAATACATCTCCAAAAGAATTATTTATTGGAAATCATAACGAAAA
CCATAAATTAGAAATTGTTCACGAAATACCTCAATAAACTTATAAATAAAAAGTAAATAA
ATTAATTAATTAATATCAATTATATAAAGAATCAACTCATTTTTAAAAAAAAGCTTAAAT
GCACGAATATATCTTGTTAGAAAGATTTATCATACTCTTTAGTACACAAATGCTTAACCT
GTTTTGAATTGTACTTATGTGAAAAGTGCTATGCAAACCAAAATAAAGTTAAGCTTCCAA
ATACCCTCAAGGATTCACATTAATACTACCATGATTTTTTTATGATTAAATGA

>TTHERM_00136470(protein)
MKRDQQESEEESEESGDDSDSVEVQRATNVRAKSYHDSNNVILGKRQRRESTKHAKDDLI
GFKEKKKKRGRKAKKKKPLPIKKKGRKKKKVSKKSQKNGQLRGNGEKREKKEKGEKVIKE
RSKVKVEDEDDEFRHQNPNLIHLSKLNKIFVLHSSEIRANKKDKKKLFQNTLLAKTPEEK
RTSQSIIECDLRYFDFTYLTNIFDSFDVVMIAPPFDAISIQEVFELKVELISKQGFLFFW
AKDVPTATSYEIMSKWGYDVIDQIIWVKIDKNEGKMILEDKPDKYFYNSNEMCLIGVKKH
PSSKGVEYQSKVSNNIIVSHQPQNQSCPDQIYDIIDLMMPGSKKIELFTKQKVIRGGWFG
LEHKFQPEINQSKNLNQQINTKESDKAAHFDHTKVQDIQAIKNNQIPIFNQQQCLKCEMK
PIVGLYFSCETCKIDTQNSFSICQDCFFNTSPKELFIGNHNENHKLEIVHEIPQQTYKQK
LKCTNISCQKDLSYSLVHKCLTCFELYLCEKCYANQNKVKLPNTLKDSHQYYHDFFMIK