Identifiers and Description

Gene Model Identifier

TTHERM_00136510

Standard Name

FIM1 (FIMbrin 1)

Aliases

PreTt24376 | 10.m00425 | 3698.m00144

Description

FIM1 fimbrin-like protein; Fimbrin-like 71 K protein; actin filament bundling protein; contains 2 alpha-actinin-type binding domains- but lacks E

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cleavage furrow (IDA) | GO:0032154
• oral apparatus (IDA) | GO:0031912

Molecular Function

• actin filament binding (IDA) | GO:0051015

Biological Process

• actin filament bundle assembly (IPI) | GO:0051017

Domains

• ( PF00307 ) Calponin homology (CH) domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_05818.1	9.997093137033517e-262
	Description: fimbrin-like 71 K protein (523 aa)
Tetrahymena borealis	EI9_03245.1	9.997093137033517e-262
	Description: hypothetical protein (1299 aa)
Oxytricha	Contig10286.0.1.g44	1.999872053281847e-142
	Description: Calponin homology (CH) domain
SGD	YDR129C	2.0000211193600847e-137
	Description: SAC6 Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton
DictyBase	DDB_G0277855	3.0001046824819247e-131
	Description: fimA on chromosome: 3 position 187950 to 189871
Stentor Coeruleus	SteCoe_4363	2.001470128041443e-75
	Description: None
WormBase	WBGene00022425	5.9981191891941984e-64
	Description: locus:plst-1 status:Partially_confirmed UniProt:U4PBU8 protein_id:CDH93209.1
WormBase	WBGene00000182	5.9981191891941984e-64
	Description: locus:arf-1.2 ADP-ribosylation factor 1-like 2 status:Confirmed UniProt:Q10943 protein_id:CCD61516.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:14607987: Shirayama S, Numata O (2003) Tetrahymena fimbrin localized in the division furrow bundles actin filaments in a calcium-independent manner. Journal of biochemistry 134(4):591-8
2. Ref:11942614: Numata O, Gonda K (2001) Determination of division plane and organization of contractile ring in Tetrahymena. Cell structure and function 26(6):593-601
3. Ref:10731670: Watanabe A, Yonemura I, Gonda K, Numata O (2000) Cloning and sequencing of the gene for a Tetrahymena fimbrin-like protein. Journal of biochemistry 127(1):85-94
4. Ref:10816251: Numata O, Gonda K, Watanabe A, Kurasawa Y (2000) Cytokinesis in Tetrahymena: determination of division plane and organization of contractile ring. Microscopy research and technique 49(2):127-35
5. Ref:9538250: Watanabe A, Kurasawa Y, Watanabe Y, Numata O (1998) A new Tetrahymena actin-binding protein is localized in the division furrow. Journal of biochemistry 123(4):607-13

Sequences

>TTHERM_00136510(coding)
ATGGATACCTTAAAGACTGCTGTAAAGACTAATGTCGAAGCTAAATAAAGCGACACAAAT
GCTATTCACTCATTTACTTAAGATGAAGTTAATGCTTACTGCGAACATATTAACTACTAT
CTTTCTGATGATGCTGACCTCAAAGAATTATTGCCAATTGATCCTTAAAGCAATAAGATT
TTTGAAGCTGTTGGAGATGGTGTCTTGCTTTGCAAATTAATCAACAAAGCCACTCCTGGT
ACTATTGACCCTAGAGCCATCAACACCAAGAACCTTAACATCTTTAAGAAAAATGAAAAC
TTAACCTTAGCTATAGCTTCTGCTAGAGCAATTGGCTGTGTTTGCGTTAATATTACAAAC
AATAGCATTATAGATAAGAGAGAACATATTATTTTGGGTCTTGTTTGGTAGATTATCAAG
GCTTAAATGTTGTTTAAGATTGACTTGAAAAACCACCCTTATTTGATTAGACTTAAAAAG
GAAGAAGAAGAAATTAGTGATCTTCTTAAACTCCCTAAAGAAGAACTTTTGATCCGTTGG
TTCAATTACCATTTAGAAAATGCTAAGCACTCAACTAAGATTAATAACTTTTCTAAGGAT
GTTTCCTCAGGTACTGAATACACAGTTTTACTCAACCAAATTGCTCCTGAAAAGTGCAAC
AAAGACGGATTAAATTTAGAACACCTTGAAAGATGCAAGAAGGTTATTAATGATTCTAAA
CTTTTGGGAGTACCTCCTTGTATTAAGCCTTCTGATATTGTAAATGGAAATCAAAAGCTT
AACTTGATTTTCTGTGCTCACTTATTCAACAATTGCCCTGGTTTAACTCCTACTGAACAA
GAAAAAATTGATGCTGCTGGCATGATAGATGATGATAACGATCCTGAAGCTTCTCGTGAA
GAAAGAGTTTTCAGAATGTGGATGAACTCTTTAAATATTGAAGATGTTTATCTTAACAAT
ATGATTCAAGATTTAAGAGATGGTATCGTTTTATGTAAGATTATGGATAAATTAGCTCCA
GGAAAAGTTGACTTGAAGAAGGTTTCAAATAAAAACTCTAAATTCACTAAAATACAAAAC
GCTAACTACGCAGTATAATTAGCTAAGGATTTACATTTATAAATTGTTGGTATTGGTGGT
ACTGATATTGTAGATGGTAACAAAAAGCTTATCCTTGCTATTGTTTGGTAACTCATGAGA
AAGTAATCATTACAGGTTATTGGTGAATTGAATGAACAAAAATTAGTAGAATGGGGTAAT
AGTAGAATTCCTCAAGATAAACATATAACTGGATTTAAAGATAAATCTCTTAAAAACTCA
CATTTCTTCTTCAAGATTATGGAATCTATTGAACCTAGAGCTATCAATTAGGATTTGATA
ACTCCTGGTGAGACTGATGAAGAAGTCACTAACAATGCTAAATACGCTATCTCTGTTGCT
CGTAAGCTTGGTGCAGCAGTTTTCCTTGTTTGGGAACACATTAGAGACGTCAATCCTAAA
TTTTTAATGACATTTACTGCTTCTCTCTACCACTGTGCTAAAGAATACGAAGGAAAGAAG
GTCTAATGA

>TTHERM_00136510(gene)
ATGGATACCTTAAAGACTGCTGTAAAGACTAATGTCGAAGCTAAATAAAGCGACACAAAT
GCTATTCACTCATTTACTTAAGATGAAGTTAATGCTTACTGCGAACATATTAACTACTAT
CTTTCTGTAATATTATTTTTATATTTTCAAAAGTTTATTCAGTTTTATCAAAAAACTTTA
GGATGATGCTGACCTCAAAGAATTATTGCCAATTGATCCTTAAAGCAATAAGATTTTTGA
AGCTGTTGGAGATGGTGTCTTGCTTTGGTAATTTCACGATTTTTCAAAAATTTGTTATAG
AATTTTATTTTGTTAATTCTATTTAGCAAATTAATCAACAAAGCCACTCCTGGTACTATT
GACCCTAGAGCCATCAACACCAAGAACCTTAACATCTTTAAGAAAAATGTAAACATATTA
AATATTTTGATTGCAAGAAAATTATTTAAAAAATAATCTCAATCAGTCAATAAAAGGAGA
ATTTTAATTCATTCCATTAAATTTATTTTCTTAAAATAGGAAAACTTAACCTTAGCTATA
GCTTCTGCTAGAGCAATTGGCTGTGTTTGCGTTAATATTACAAACAATAGCATTATAGAT
AAGAGAGAACATATTATTTTGGGTCTTGTTTGGTAGATTATCAAGGTATTTATTTTATTT
TTGGATTTTTTTTTCTTAAATGTTTGTTTGTTTATTAAATATGTGAATATTTCAGACCTT
CAATATGTTTTTTATAATAAAAAGGCTTAAATGTTGTTTAAGATTGACTTGAAAAACCAC
CCTTATTTGATTAGACTTAAAAAGGAAGAAGAAGAAATTAGTGATCTTCTTAAACTCCCT
AAAGAAGAACTTTTGATCCGTTGGTTCAATTACCATTTAGAAAATGCTAAGCACTCAACT
AAGATTAATAACTTTTCTAAGGATGTTTCCTCAGGTATTTGAAATGAGCTTATTGAATAT
TAATTAAGGCATTTATATATCCGAAAAAAAATTTTTATAAATAGAATAAGAAAAATAATT
AATTTTATTTTTAAATTAAATTAGGTACTGAATACACAGTTTTACTCAACCAAATTGCTC
CTGAAAAGTGCAACAAAGACGGATTAAATTTAGAACACCTTGAAAGATGCAAGAAGGTTA
TTAATGATTCTAAACTTTTGGGAGTACCTCCTTGTATTAAGCCTTCTGATATTGTAAATG
GAAATCAAAAGCTTAACTTGATTTTCTGTGCTCACTTATTCAACAATTGCCCTGGTTTAA
CTCCTACTGAACAAGAAAAAATTGATGCTGCTGGCATGATAGATGATGATAACGATCCTG
AAGCTTCTCGTGAAGAAAGAGGTAAATAAGAAATTTATTAAAAATTCAGATTAAATTCTT
ATTTTAACTCGCATACACTGAGCATTTGAATTTAAGTTTAATTTCTGAAAAAAGATTTTA
TATATCTTATACAAATATTTAGCCCATATTATCAATATCAGTTTAGTTTTTAAAGAAAAG
TAATTAACTAAATCAAAGATATTATTTAAGATTACTGGATAGGAAAAGATTGCTATGTAA
TTAATGGAAAAATAAGCTATCTTAATAAAATTTATCTCTATATCTTTATACCGATCAGTC
AAATAATTAAATGTTAATTTCACTGAGAAAAAAACTTTTTTGAAGAATAAAAATAATTAA
CTTTTTTGGATTCATTTAAAATGAAATTAATGGTTTTAAATTTCAATAATTTATCAGTAA
AAATTTGAAAAAGTTAATTTTATCCTAAAATTTTATTCTTTTTATATCAAATTTCTATTT
TAAGGTATGGTATTATATCATTTTTAATAAAAAATCTATCTATACATAGTTTTCAGAATG
TGGATGAACTCTTTAAATATTGAAGATGTTTATCTTAACAATATGATTCAAGATTTAAGA
GATGGTATCGTTTTATGTAAGATTATGGATAAATTAGCTCCAGGAAAAGTTGACTTGAAG
AAGGTTTCAAATAAAGTAAAAAATTGAATGAATTTTCTAAAAGTTTATTTTAAATTTAAT
TAATTTATTTCTTTATTAAATTAAAAATAGAACTCTAAATTCACTAAAATACAAAACGCT
AACTACGCAGTATAATTAGCTAAGGATTTACATTTATAAATTGTTGGTATTGGTGGTACT
GATATTGTAGATGGTAACAAAAAGCTTATCCTTGCTATTGTTTGGTAACTCATGAGAAAG
TAATCATTACAGGTAATAAACAATAAGCAAATTTTAATACAAAAAATCTATCAAAAATTA
TATCTGATAGCTTATTCATTCATTAATATTATAAATAGTAGTTAAAGGCGTTTTGAATTT
TAATTTAATAATAGGTTATTGGTGAATTGAATGAACAAAAATTAGTAGAATGGGGTAATA
GTAGAATTCCTCAAGATAAACATATAACTGGATTTAAAGATAAATCTCTTAAAAACTCAC
ATTTCTTCTTCAAGATTATGGAATCTATTGAACCTAGAGCTATCAATTAGGATTTGATAA
CTCCTGGTGAGACTGATGAAGAAGTCACTAACAATGCTAAATACGCTATCTCTGTTGCTC
GTAAGCTTGGTGCAGCAGTTTTCCTTGTTTGGGAACACATTAGAGACGTAAAATTAAAAA
TCAAATCTTATTATTATATAATAAATTATAATTCATTTTATAAAATAGGTCAATCCTAAA
TTTTTAATGACATTTACTGCTTCTCTCTACCACTGTGCTAAAGAATACGAAGGAAAGAAG
GTCTAATGA

>TTHERM_00136510(protein)
MDTLKTAVKTNVEAKQSDTNAIHSFTQDEVNAYCEHINYYLSDDADLKELLPIDPQSNKI
FEAVGDGVLLCKLINKATPGTIDPRAINTKNLNIFKKNENLTLAIASARAIGCVCVNITN
NSIIDKREHIILGLVWQIIKAQMLFKIDLKNHPYLIRLKKEEEEISDLLKLPKEELLIRW
FNYHLENAKHSTKINNFSKDVSSGTEYTVLLNQIAPEKCNKDGLNLEHLERCKKVINDSK
LLGVPPCIKPSDIVNGNQKLNLIFCAHLFNNCPGLTPTEQEKIDAAGMIDDDNDPEASRE
ERVFRMWMNSLNIEDVYLNNMIQDLRDGIVLCKIMDKLAPGKVDLKKVSNKNSKFTKIQN
ANYAVQLAKDLHLQIVGIGGTDIVDGNKKLILAIVWQLMRKQSLQVIGELNEQKLVEWGN
SRIPQDKHITGFKDKSLKNSHFFFKIMESIEPRAINQDLITPGETDEEVTNNAKYAISVA
RKLGAAVFLVWEHIRDVNPKFLMTFTASLYHCAKEYEGKKVQ