Identifiers and Description

Gene Model Identifier

TTHERM_00137610

Standard Name

Aliases

PreTt24387 | 10.m00436 | 3698.m00154

Description

SNF2 family amine-terminal protein; SNF2 family N-terminal domain containing protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

Domains

  • ( PF00176 ) SNF2 family N-terminal domain
  • ( PF00270 ) DEAD/DEAH box helicase
  • ( PF00271 ) Helicase conserved C-terminal domain
  • ( PF04851 ) type III restriction enzyme, res
  • ( PF05979 ) Bacterial protein of unknown function
  • ( PF08597 ) Translation initiation factor eIF3 subunit
  • ( PF09110 ) HAND
  • ( PF09111 ) SLIDE
  • ( TIGR00034 ) 3-deoxy-7-phosphoheptulonate synthase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Stentor Coeruleus SteCoe_6435 0
Description: None
WormBase WBGene00002169 9.997093137033517e-262
Description: locus:isw-1 Chromatin-remodeling complex ATPase chain isw-1 status:Confirmed UniProt:P41877 protein_id:CCD70709.1
Tetrahymena borealis EI9_05826.1 9.997093137033517e-262
Description: SNF2 family domain-containing protein (1225 aa)
DictyBase DDB_G0292948 9.997093137033517e-262
Description: isw on chromosome: 6 position 2254360 to 2258387
Oxytricha Contig16241.0.g102 9.997093137033517e-262
Description: SNF2 family N-terminal domain
SGD YOR304W 9.997093137033517e-262
Description: ISW2 ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth

General Information

No. Gene Name(s) Paragraph Text
126 (no standard gene name) This protein is homologous to proteins that contain helicase and SANT domains, which are associated with transcription. It contains three domains; the first two domains (score=22.832, 18.839), in the helicase family, indicates that the protein’s function, which involves the binding of ATP, could be related to the separation of double-stranded nucleic acids. The third domain (score=10.421) belongs to the SANT domain, which indicates that the protein is involved in chromatin-remodeling or transcription regulation via protein-protein interactions. The closest homologs are in Ichthyophthirius multifiliis, with 77% identical residues and Pseudocohnilembus persalinus,with 54% identical residues. It is possible that this protein is an enzyme with helicase activity that functions to remodel chromatin or regulate transcription. Paragraph by: Madison Seto, Keck Science Department, Scripps College

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00137610(coding)
ATGGCTGATGAAACTAACGAAAAATCCAGAGGATTTGAGGATGTCATGGATGAAGAAGAT
GATGTCCATGAAGTAGAAAAAATATAGGGTAGGAAGAGTTAGCAATAAAAATATCTGAAA
TAAATAAGCAACGACGATGAAAATCCATAGCAAGAGGAGATAAGCGATGTTGAGAAGAAA
ATGAAAACTCTTCTGCTGAAAGCTGAATAATATGCAAGTTTTTTAGTTTCAAGACATTAA
TAGAAAAAGAATAAAAAGCAAGTTGTTCAAAAAAGAAGAGGGTAATATTAGGAAGAGAAA
GAAGAAGAAGAGTAGCTTATTAAAGAGGAAGAAGAAGAGGATGATAACTTGCCTACCATA
CTAACAAGCTAGCCAAAAATATTAAAGGGAGGAAAATTAAAAGATTATCAAATGATTGGT
CTTAATTGGATGATCAGTTTATATGAAACTGGTTTAAATGGTATATTAGCCGATGATATG
GGTCTTGGTAAAACAATTTAATCTATCTCTTTAATAGGTTTCCTGAAAGAATTTAAAAAA
ATAAATGGTCCACATTTAATTATAGCTCCTAAGAGTACTTTAGGTAATTGGTTTAACGAA
TTTCAGAAATGGTTGCCTTGCTGCAGAACAATCAAATTAATTGCAACAAAAGATGAAAGA
GAAGAAATTTTGTAAAATTATATCGCTAATAGCAAATTTGATGTTTGTTTAACAAGTTTT
GAAGGAGCAAAGCTTTGCTAAAAATATTTGAAAAAAATAAATTTCTAATATATTATTATT
GATGAAGCTCACAAGATTAAAAACGAAGAGAGTTAAACTGCTTTGATTTTAAGAATGTTT
AAAACTAATTATAAAATATTGCTCACTGGTACTCCCCTCTAAAACAACCTTCACGAATTG
TGGAGTTTGCTCAACTTTTTATTGCCAGATTTATTCAGCTCAAGTGAGATTTTTGATGAA
TGGTTCAGTGCTAACAATTTGAGTGGCAAAAATAATAACGAAGAAAATGACACAAAGAAT
ATTGAAATGATATCTCAGCTTCATAGAATTTTGAAACCATTTATGATGCGTAGAACTAAA
TCTGAAGTTATGCAAACACTTCCTCCTAAAAAGGAAATCCATTTATATGTAGGTTTGACT
GAATCACAATTAAATATATATAGAAATCTCCTATCTCCTAAGAAAAGTATAACAGGATCT
GAGGATGATAAGAAATTCTATCTTAATATCTTAATGCAACTTAGAAAAGTTTGCAATCAT
CCTTATTTGTTTGAAGGAATAGAAGAAGAAGGGCTCCCACCTCTAGGTGAGCACATTATT
ACTAATTGTGGTAAAATGATGGTCTTAGATAAATTGTTACAAAAACTAAAAAATGGAAAG
CATTAAGTGCTTATTTTCTCTTAAATGACTATGGTTTTAGATATATTAGAGGATTATTGT
AACTACAGACAGTTTAAATATTGCCGTATCGACGGTAATACAGATATGACTGATAGAGAT
AATTAAATTAGTGATTTTGTAAAAGAAGACTCAACTAAATATATTTTCCTTTTGAGTACA
AGAGCAGGTGGTTTAGGTATCAACTTAGCTACAGCAGATACAGTTGTTTTATATGATTCT
GATTGGAATCCATAAATGGATTTATAGGCCATGGACAGAGCTCACAGAATAGGTTAAAAG
AATATCGTTAACGTTTATAGATTAATATCTGAAAATACAATTGAAGAAAAAATTATCGAA
AGATAAACAATTAAATTAAAATGGGATCAATTGATTATTCAGTAGGGTAGACTTGCTTAA
AAGAATCGTGTTCTCTCAAGAGACGAAATTAAGGATATGATTTAATTTGGAGCTTCTGCT
ATTTTCAAATCCAAAGGGGGAACATACACAGATGAGGATATTGACATTCTTCTGTAGAGA
GGTGAGTAAAAAACCAAAGACCATAATAAAACCATTGATGAAAAATTCAAGAAATCTAAT
GAATAAGTGGGAGAATTATCTCTTAGCTCTATCAATATTTATGATTTCTTGTAAAAGAAC
CACGATAATGACAAAACAAAAGAAGATAAAGAAGCCTTAGATGAATAGTTAGCCCGTGAG
TTAGCTAGTGAATTAAGATCTCGTAGAGAAAAGAAGACTATGAATTACAATATCAATGCA
TAGTTTTCACATATGATGGCAACTGCTCCTATGCCTAAGGCTGCTAAAATAATTAAATTA
CCAGAACATTAATTGTTTGTAGAAAGAGAAAAACTTTAAGAATTACTTCAAAAGGAAGAA
GATTTTAAATGCATGAGCAACAGAGCTAAAAAAGCTGAAAAAGAGGAAGAAAATTCAATT
GAAGAAAATGGGCTTACTCCCAAAGAAAACAAACTAAAGGATTAATATTGGGCTACAGGT
TTTCCTACTTGGTTGAAACAAGAATATCTCAGTTTCATTCAAGGATGTGAAAGATTTGGA
AAGACTGCCTACAAAGAAATAGCTGAGCACATCAAGACAAAAACAGAAGAAGAAGTTAGC
TAATATAGCAAAGCCTTTTGGGAAAGAATCGACACAATCAGTGAAAAAGATAAAATCATT
AAGAACATTGAAAGAGGAGAGTAAATTCTTAAGTAGAAATTAGTGATGTCAGACTTATTA
AAAGAGAGATGCAAAATTTATCAAAATGTTAAAGAAGAGTTTGAATTCAATTCAGCCATT
TACAATAAATCTAAATCTAAATTCTACACAACTGAAAATGATAAATTTTTAATTTATGCT
AGTTATCAAATGGGGTACTGCAATTGGCCTGTCATCATAAAAGAAATAAAAACTAATCCT
ATGTTTTAATTTGATCACTTTTTCAAAAGCAGAAGTGAATACGAGTTAAATAAAAGACTT
TAGAGTCTATTAAAAGTAGTAGAAAAGGAGAAAGATTTTATTGTTTAAATTGAAGCTAAA
AAGCTAAAATTAAAGTAAGAGTAGGAAGAGAAGTAAAGAGAGCAAGAACTCAAAAAGGAA
TAATAGAAATAGTAACAATAATTACTCGAATAGTAAAAGGCTGAAAAAGAAAAAGCTAAT
CAACAATAACAACAACAACAGTAATAATAATAATTGAATACAGAAATTATAGTTACAGAT
AGCTAGCCAAAGCCATAATAAAATAGCAACAATAACAAAGATAGTAAAAATATAAATTCT
GCTAAAAATAGCTAAGAATCTTAAGCTAAATAATAAAGTACTATCTAAAAGTCTAGTAAT
TAACAATCTAACTAAGTCCAACAAACTTAAAAAATTAAAGATCCACAAAACTCTTCTTCT
TCTAAAAATAATAATACTAATAGTAAAACAAATGGCTTAAAATAAAATTCTCTATTAAAT
TATGGTGTAAAAGTAGATAAAAAAGTATAACAAGCACCTATTTTGATAGACTTAGAATCA
GAAGATGAAGAAGATGATAAAATAAAAATTAAAAGATTACCAAATGTAATTGTGCCAGAG
CCTTTATCATAAGAAAGTAAGCAAGAAACCTAATAGAAGTAATCATAGTAATCTTCACAA
TCAAGTAATAAATAAAGCACTAGCAATGCATCAAATAATATAAATTCTAAAAAATCTCAC
AATGTTAAAGACGATAAAATAGAATAAAATCCTTAAAAAAAGTTAAAGCGTGATTGA


>TTHERM_00137610(gene)
ATGGCTGATGAAACTAACGAAAAATCCAGAGGATTTGAGGATGTCATGGATGAAGAAGAT
GATGTCCATGAAGTAGAAAAAATATAGGGTAGGAAGAGTTAGCAATAAAAATATCTGAAA
TAAATAAGCAACGACGATGAAAATCCATAGCAAGAGGAGGTAACAATCAATTAACGATAT
ATTTTAAAAAAAGAAATGTGAGAGAAAGTCATATTTTTGAATAAAAAATTATTTTTTTAA
TAAATTTAGATAAGCGATGTTGAGAAGAAAATGAAAACTCTTCTGCTGAAAGCTGAATAA
TATGCAAGTTTTTTAGTTTCAAGACATTAATAGAAAAAGTAAATATAAACAAATATTTTA
AAAATGCTTTATAAAAGCTTAGCAATTATCAAAATATTTTAAGTATTTCACAAAAATAAA
ATGAGTAATTTCATCATTATAAAATATTTTTAGGAATAAAAAGCAAGTTGTTCAAAAAAG
AAGAGGGTAATATTAGGAAGAGAAAGAAGAAGAAGAGTAGCTTATTAAAGAGGAAGAAGA
AGAGGATGATAACTTGCCTACCATACTAACAAGCTAGCCAAAAATATTAAAGGGAGGAAA
ATTAAAAGATTATCAAATGATTGGTCTTAATTGGATGATCAGTTTATATGAAACTGGTTT
AAATGGTATATTAGCCGATGATATGGGTCTTGGTAAAACAATTTAATCTATCTCTTTAAT
AGGTTTCCTGAAAGAATTTAAAAAAATAAATGGTAAATATTGACATTGTGTGAAAAAATA
TGCAATTAAAACTATTTAAAATAAAGGTCCACATTTAATTATAGCTCCTAAGAGTACTTT
AGGTAATTGGTTTAACGAATTTCAGAAATGGTTGCCTTGCTGCAGAACAATCAAATTAAT
TGCAACAAAAGATGAAGTAAAAATTTTTAAAAAAGTTAATAATGATACTCAATTTACATT
ATTGTTTATTATAGAGAGAAGAAATTTTGTAAAATTATATCGCTAATAGCAAATTTGATG
TTTGTTTAACAAGTTTTGAAGGAGCAAAGCTTTGCTAAAAATATTTGAAAAAAATAAATT
TCTAATATATTATTATTGATGAAGCTCACAAGATTAAAAACGAAGAGAGTTAAACTGCTT
TGATTTTAAGAAGTATATTTCATTCATTTATAATCTCAAATTTTGATATTAATTATTCTT
ACATTCAAATAGTGTTTAAAACTAATTATAAAATATTGCTCACTGGTACTCCCCTCTAAA
ACAACCTTCACGAATTGTGGAGTTTGCTCAACTTTTTATTGCCAGATTTATTCAGCTCAA
GTGAGATTTTTGATGAATGGTTCAGTGCTAACAATTGTAAGATATTGTTTTAAAATTTAA
ATCAAGCTTATTTATAAATTTCATTTTAGTGAGTGGCAAAAATAATAACGAAGAAAATGA
CACAAAGAATATTGAAATGATATCTCAGCTTCATAGAATTTTGAAACCATTTATGATGCG
TAGAACTAAATCTGAAGTTATGCAAACACTTCCTCCTAAAAAGGAAATCCATTTATATGT
AGGTTTGACTGAATCACAATTAAATATATATAGAAATCTCCTATCTCCTAAGAAAAGTAT
AACAGGATCTGAGGATGATAAGAAATTCTATCTTAATATCTTAATGCAACTTAGAAAAGT
TTGCAATCATCCTTATTTGTTTGAAGGAATAGAAGAAGAAGGGCTCCCACCTCTAGGTGA
GCACATTATTACTAATTGTGGTAAAATGATGTAATTAAAATATTTAATAAATAATTGATT
CCATTTAATCAAAATTTATTTCCTAAATAGGGTCTTAGATAAATTGTTACAAAAACTAAA
AAATGGAAAGCATTAAGTGCTTATTTTCTCTTAAATGACTATGGTTTTAGGTAAATTTTA
ATAAATGTTTAAATTTTAATATCTTTCTTTGTTACTTATGAAAATAATAGATATATTAGA
GGATTATTGTAACTACAGACAGTTTAAATATTGCCGTATCGACGGTAATACAGATATGAC
TGATAGAGATAATTAAATTAGTGATTTTGTAAAAGAAGACTCAACTAAATATATTTTCCT
TTTGAGTACAAGAGCAGGTGGTTTAGGTATCAACTTAGCTACAGCAGATACAGTTGTTTT
ATATGATTCTGATTGGAATCCATAAATGGATTTATAGGGTAAAGATTTTATTTCAAAAAA
ACAAACAAACAATTAATGATTTTTAAATTAAATTAGCCATGGACAGAGCTCACAGAATAG
GTTAAAAGAATATCGTTAACGTTTATAGATTAATATCTGAAAATACAATTGAAGAAAAAA
TTATCGAAAGATAAACAATTAAATTAAAATGGGATCAATTGATTATTCAGTAGGGTAGAC
TTGCTTAAAAGAATCGTGTTCTCTCAAGAGACGAAATTAAGGATATGATTTAATTTGGAG
CTTCTGCTATTTTCAAATCCAAAGGGGGAACATACACAGATGAGGGTAAAAATTATTCCC
AAAGTTAAAGTAAAAATGATAATATAATTAATATTTATAGATATTGACATTCTTCTGTAG
AGAGGTGAGTAAAAAACCAAAGACCATAATAAAACCATTGATGAAAAATTCAAGAAATCT
AATGAATAAGTGGGAGAATTATCTCTTAGCTCTATCAATATTTATGATTTCTTGTAAAAG
AACCACGATAATGACAAAACAAAAGAAGATAAAGTAAAATTACTTTTAAAATGAGATATT
AAATATATTCTGAAATATTTAATAGGAAGCCTTAGATGAATAGTTAGCCCGTGAGTTAGC
TAGTGAATTAAGATCTCGTAGAGAAAAGAAGACTATGAATTACAATATCAATGCATAGTT
TTCACATATGATGGCAACTGCTCCTATGCCTAAGGCTGCTAAAATAATTAAATTACCAGA
ACATTAATTGTTTGTAGAAAGAGAAAAACTTTAAGAATTACTTCAAAAGGAAGAAGATTT
TAAATGCATGAGCAACAGAGCTAAAAAAGCTGAAAAAGAGGAAGAAAATTCAATTGAAGA
AAATGGGCTTACTCCCAAAGAAAACAAACTAAAGGATTAATATTGGGCTACAGGTTTTCC
TACTTGGTTGAAACAAGAATATCTCAGTTTCATTCAAGGATGTGAAAGATTTGGAAAGAC
TGCCTACAAAGAAATAGCTGAGGTAATTTTTTCAAAAGTTGTTGTTGCTATAAAAGTTAA
AATAATTTTATTTTAAACATAAATAGCACATCAAGACAAAAACAGAAGAAGAAGTTAGCT
AATATAGCAAAGCCTTTTGGGAAAGAATCGACACAATCAGTGAAAAAGATAAAATCATTA
AGAACATTGAAAGAGGAGAGTAAATTCTTAAGTAGAAATTAGTGATGTCAGACTTAGTAA
ATAATATTCATTCATTTTATGAGCTTTTTCAAATAAAAATATTTATTTCTTCAAATTTTT
AGTTAAAAGAGAGATGCAAAATTTATCAAAATGTTAAAGAAGAGTTTGAATTCAATTCAG
CCATTTACAATAAATCTAAATCTAAATTCTACACAACTGAAAATGATAAATTTTTAATTT
ATGCTAGTTATCAAATGGGGTACTGCAATTGGCCTGTCATCATAAAAGAAATAAAAACTA
ATCCTATGTTTTAATTTGATCACTTTTTCAAGTAAATTAAAAAAAAATTTTATTTAATTT
AAATATATTTTATTAAACTTACAGAAGCAGAAGTGAATACGAGTTAAATAAAAGACTTTA
GAGTCTATTAAAAGTAGTAGAAAAGGAGAAAGATTTTATTGTTTAAATTGAAGCTAAAAA
GCTAAAATTAAAGTAAGAGTAGGAAGAGAAGTAAAGAGAGCAAGAACTCAAAAAGGAATA
ATAGAAATAGTAACAATAATTACTCGAATAGTAAAAGGCTGAAAAAGAAAAAGCTAATCA
ACAATAACAACAACAACAGTAATAATAATAATTGAATACAGAAATTATAGTTACAGATAG
CTAGCCAAAGCCATAATAAAATAGCAACAATAACAAAGATAGTAAAAATATAAATTCTGC
TAAAAATAGCTAAGAATCTTAAGCTAAATAATAAAGTACTATCTAAAAGTCTAGTAATTA
ACAATCTAACTAAGTCCAACAAACTTAAAAAATTAAAGATCCACAAAACTCTTCTTCTTC
TAAAAATAATAATACTAATAGTAAAACAAATGGCTTAAAATAAAATTCTCTATTAAATTA
TGGTGTAAAAGTAGATAAAAAAGTATAACAAGCACCTATTTTGATAGACTTAGAATCAGA
AGATGAAGAAGATGATAAAATAAAAATTAAAAGATTACCAAATGTAATTGTGCCAGAGCC
TTTATCATAAGAAAGTAAGCAAGAAACCTAATAGAAGTAATCATAGTAATCTTCACAATC
AAGTAATAAATAAAGCACTAGCAATGCATCAAATAATATAAATTCTAAAAAATCTCACAA
TGTTAAAGACGATAAAATAGAATAAAATCCTTAAAAAAAGTTAAAGCGTGATTGA


>TTHERM_00137610(protein)
MADETNEKSRGFEDVMDEEDDVHEVEKIQGRKSQQQKYLKQISNDDENPQQEEISDVEKK
MKTLLLKAEQYASFLVSRHQQKKNKKQVVQKRRGQYQEEKEEEEQLIKEEEEEDDNLPTI
LTSQPKILKGGKLKDYQMIGLNWMISLYETGLNGILADDMGLGKTIQSISLIGFLKEFKK
INGPHLIIAPKSTLGNWFNEFQKWLPCCRTIKLIATKDEREEILQNYIANSKFDVCLTSF
EGAKLCQKYLKKINFQYIIIDEAHKIKNEESQTALILRMFKTNYKILLTGTPLQNNLHEL
WSLLNFLLPDLFSSSEIFDEWFSANNLSGKNNNEENDTKNIEMISQLHRILKPFMMRRTK
SEVMQTLPPKKEIHLYVGLTESQLNIYRNLLSPKKSITGSEDDKKFYLNILMQLRKVCNH
PYLFEGIEEEGLPPLGEHIITNCGKMMVLDKLLQKLKNGKHQVLIFSQMTMVLDILEDYC
NYRQFKYCRIDGNTDMTDRDNQISDFVKEDSTKYIFLLSTRAGGLGINLATADTVVLYDS
DWNPQMDLQAMDRAHRIGQKNIVNVYRLISENTIEEKIIERQTIKLKWDQLIIQQGRLAQ
KNRVLSRDEIKDMIQFGASAIFKSKGGTYTDEDIDILLQRGEQKTKDHNKTIDEKFKKSN
EQVGELSLSSINIYDFLQKNHDNDKTKEDKEALDEQLARELASELRSRREKKTMNYNINA
QFSHMMATAPMPKAAKIIKLPEHQLFVEREKLQELLQKEEDFKCMSNRAKKAEKEEENSI
EENGLTPKENKLKDQYWATGFPTWLKQEYLSFIQGCERFGKTAYKEIAEHIKTKTEEEVS
QYSKAFWERIDTISEKDKIIKNIERGEQILKQKLVMSDLLKERCKIYQNVKEEFEFNSAI
YNKSKSKFYTTENDKFLIYASYQMGYCNWPVIIKEIKTNPMFQFDHFFKSRSEYELNKRL
QSLLKVVEKEKDFIVQIEAKKLKLKQEQEEKQREQELKKEQQKQQQQLLEQQKAEKEKAN
QQQQQQQQQQQLNTEIIVTDSQPKPQQNSNNNKDSKNINSAKNSQESQAKQQSTIQKSSN
QQSNQVQQTQKIKDPQNSSSSKNNNTNSKTNGLKQNSLLNYGVKVDKKVQQAPILIDLES
EDEEDDKIKIKRLPNVIVPEPLSQESKQETQQKQSQQSSQSSNKQSTSNASNNINSKKSH
NVKDDKIEQNPQKKLKRD