Identifiers and Description

Gene Model Identifier

TTHERM_00138080

Standard Name

FIB1 (FIBrillarin 1)

Aliases

FIB | PreTt24434 | PreTt24435 | 10.m00484 | 3698.m00201

Description

FIB1 rRNA 2-prime-O-methyltransferase fibrillarin; Fibrillarin; essential protein localized to nucleoli in the macronucleus of vegetative cells; involved in rRNA processing; associates with U3 snoRNA; rRNA 2'-O-methyltransferase fibrillarin-like

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• macronucleus (IDA) | GO:0031039
• nucleolus (IDA) | GO:0005730

Molecular Function

• snoRNA binding (IPI) | GO:0030515

Biological Process

• rRNA processing (ISS) | GO:0006364

Domains

• ( PF01269 ) Fibrillarin

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:9201715: David E, McNeil JB, Basile V, Pearlman RE (1997) An unusual fibrillarin gene and protein: structure and functional implications. Molecular biology of the cell 8(6):1051-61

Sequences

>TTHERM_00138080(coding)
ATGGGTAAAGATTTCAAGTCAGGTGGTGGCAATGCTGGTGGAAAGCCCTTCAATAAAGGT
CCTGGAGGTCCTGGTGGAAGACCCTTCAATAAGGGTCCTGGTGGTCCCGGTGGTCCTGGT
GGCAAATTCGGTGGTGGCAGACCCGGTGGCCCTGGTGGCAAATTTGGTGCCAAGGGTCCT
AGAGGTCCCAAGACTATTATTGTTAAGCATAGATTAGAAGGTGTTTTCATCTGCAAAGGT
CAATAAGAAGCTTTGGTAACTAAAAATTTCTTCCCTGGTGAATCTGTTTACAATGAAAAA
CGTATGTCCGTTGAAGAAAACGGTGAAAAGATTGAATATCGTGTCTGGAATCCCTACAGA
TCTAAAATTGCTGCTGCTGTTGTTGGTGGTATTTCTGATATTCATATTAAACCTGGCTCC
AAGGTTCTCTATTTGGGTGGTGCCTCTGGTACAACTGTCTCTCACGTTGCTGATATTGTT
GGACCCACTGGTGTTGTCTATGCTGTCGAATTCTCTCACAGAAGTGGTAGAGATTTGGTA
AATATGGCTAAGAAGAGAACCAATGTTGTTCCCATTATCGGTGATGCTAGAAAGCCCCAA
GAATACAGATTCTTAGTCGGTATGGTCGATGTCGTCTTCGCTGATGTTGCCCAACCTGAT
CAAGCTAGAATTATGGGTATGAACTGTTAATACTTCTTAAAGAATGGTGGTCACTTCCTT
ATCTCCATTAAGGCTTGCTGTATTGATTCAACCAACGAACCTGCAGTCGTTTTCGCTGCT
GAAGTACAAAAATTAAAAGAAGAAGGTCTCAAGCCTGAATAATAACTTACTCTTGAACCT
TATGAAAGAGATCACGCTATGGTCCTCGGTTCTTACAGAGCTTGA

>TTHERM_00138080(gene)
ATATATTAAAAGAGGAAGGTCTAATAAATATAATAAATACAATAAGAGCAAACTAAATTC
AAAGAATTAACAATAAAAAATAGAAAGATAAAATTAATTAAAAAACCAAAAAAACTAATT
AAATAACATAACTAAAGCAAAAATAAAATGGGTAAAGATTTCAAGTCAGGTGGTGGCAAT
GCTGGTGGAAAGCCCTTCAATAAAGGTCCTGGAGGTCCTGGTGGAAGACCCTTCAATAAG
GGTCCTGGTGGTCCCGGTGGTCCTGGTGGCAAATTCGGTGGTGGCAGACCCGGTGGCCCT
GGTGGCAAATTTGGTGCCAAGGGTCCTAGAGGTCCCAAGACTATTATTGTTAAGCATAGA
TTAGAAGGTGTTTTCATCTGCAAAGGTCAATAAGAAGCTTTGGTAACTAAAAATTTCTTC
CCTGGTGAATCTGTTTACAATGAAAAACGTATGTCCGTTGAAGAAAACGGTGAAAAGATT
GAATATCGTGTCTGGAATCCCTACAGATCTAAAATTGCTGCTGCTGTTGTTGGTGGTATT
TCTGATATTCATATTAAACCTGGCTCCAAGGTTCTCTATTTGGGTGGTGCCTCTGGTACA
ACTGTCTCTCACGTTGCTGATATTGTTGGACCCACTGGTGTTGTCTATGCTGTCGAATTC
TCTCACAGAAGTGGTAGAGATTTGGTAAATATGGCTAAGAAGAGAACCAATGTTGTTCCC
ATTATCGGTGATGCTAGAAAGCCCCAAGAATACAGATTCTTAGTCGGTATGGTCGATGTC
GTCTTCGCTGATGTTGCCCAACCTGATCAAGCTAGAATTATGGGTATGAACTGTTAATAC
TTCTTAAAGAATGGTGGTCACTTCCTTATCTCCATTAAGGCTTGCTGTATTGATTCAACC
AACGAACCTGCAGTCGTTTTCGCTGCTGAAGTACAAAAATTAAAAGAAGAAGGTCTCAAG
CCTGAATAATAACTTACTCTTGAACCTTATGAAAGAGATCACGCTATGGTCCTCGGTTCT
TACAGAGCTTGATAGATACTTCTTTATTTAACCACTTCTCTATATATAATAACAATCTTT
CTTAAAATTGTAACTAAATACTTATCTTAGTTTTCTAGCGTAAAAGTGAAAATCGTCACC
ACAGCAGATTCCTGATAGTTTTGATAATAAAAATTAACAAACAATAAATTAGCAGAATTA
ATAAATCGAAGTTAGTAATTACAAGAAAAGTAGAATCAATCACAAGCTAAATATGAAATT
TTATCAGTTTTAAAGACAATAAAATCAATTAGTCCTAGTACTCAAATTTTAATCAAGTGA
AGCAAACAGATAAAATTCACACACTAACAAAAATTTGATTACCAGAAACCATGTGATTAA
TGCACACAGATATTCCTGTAATTATAGCAATAAAATTATATATCCTACATACATAAAAAA
AATTGCTGAAATAAAATAAATAATTAATTAATTTTTAGAAAATTATAATATTATATATGA
TATGATGACTATGCATACATACATTTGCTATCTGTTTATTGTAACTTAATTTTTATTATC
TCTGCTGACTGATGAAGAGGCAGATTTTTCCAATTCTAATTTCTACTCACTAAAATCCAT
AAATAAAGAATATTTTAACACTTAGTTAACTAAAAATTAGAAAATACTATGATGCATTAC
ATTGCACATATTTGAATATCTTTTTTAAAAGTACTAAAAACATAGATTATTTATTTATTA
GTTTATACCAAATATATTTGTAATTG

>TTHERM_00138080(protein)
MGKDFKSGGGNAGGKPFNKGPGGPGGRPFNKGPGGPGGPGGKFGGGRPGGPGGKFGAKGP
RGPKTIIVKHRLEGVFICKGQQEALVTKNFFPGESVYNEKRMSVEENGEKIEYRVWNPYR
SKIAAAVVGGISDIHIKPGSKVLYLGGASGTTVSHVADIVGPTGVVYAVEFSHRSGRDLV
NMAKKRTNVVPIIGDARKPQEYRFLVGMVDVVFADVAQPDQARIMGMNCQYFLKNGGHFL
ISIKACCIDSTNEPAVVFAAEVQKLKEEGLKPEQQLTLEPYERDHAMVLGSYRA