Identifiers and Description

Gene Model Identifier

TTHERM_00149980

Standard Name

YRS2 (tyrosyl-tRNA synthetase 2)

Aliases

PreTt20758 | 12.m00432 | 3700.m00153

Description

YRS2 tyrosyl-tRNA synthetase protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IEA) | GO:0005737

Molecular Function

• aminoacyl-tRNA ligase activity (IEA) | GO:0004812
• ATP binding (IEA) | GO:0005524
• nucleotide binding (IEA) | GO:0000166

Biological Process

• translation (IEA) | GO:0006412
• tRNA aminoacylation for protein translation (IEA) | GO:0006418

Domains

• ( PF00579 ) tRNA synthetases class I (W and Y)
• ( TIGR00233 ) tryptophan--tRNA ligase
• ( TIGR00234 ) tyrosyl-tRNA synthetase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_05061.1	9.997093137033517e-262
	Description: hypothetical protein (435 aa)
WormBase	WBGene00021200	9.997093137033517e-262
	Description: locus:cyp-31A3 status:Partially_confirmed UniProt:Q9N574 protein_id:CCD68717.1
Oxytricha	Contig1758.0.g107	2.0009356157506544e-160
	Description: tRNA synthetases class I (W and Y)
DictyBase	DDB_G0276721	5.998558726299043e-153
	Description: tyrS on chromosome: 2 position 7137404 to 7138750
Stentor Coeruleus	SteCoe_14797	1.462486227251231e-31
	Description: None
SGD	YGR185C	1.999981404597394e-31
	Description: TYS1 Cytoplasmic tyrosyl-tRNA synthetase, required for cytoplasmic protein synthesis; interacts with positions 34 and 35 of the tRNATyr anticodon; mutations in human ortholog YARS are associated with Charcot-Marie-Tooth (CMT) neuropathies
WormBase	WBGene00013677	0.00000000009998509410508463
	Description: status:Confirmed UniProt:G5ED95 protein_id:CAD21668.2
Tetrahymena borealis	EI9_17912.1	0.00000000009998509410508463
	Description: hypothetical protein (247 aa)

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00149980(coding)
ATGGATACAAAAATCAACTACTTGACTGGTGGATTGCAATTTAAGCTTCATGACGATATC
GAAGAAGAAGTAGTTTAGCTTAAATAAAATCTTTAAAGAATGTATAAACCAATAGCACCC
TCCGTAGATTTAAATGCTGCTTTTGACCCTTAACCCAGCAAGTTATCTTTGAAACAAAGA
TTCTAACTCATTAAGAGTTTTGCTGAAGAAATAATTCAAGAAAATGAACTCGTAAAGTTA
TTATCTACAAAGCAATTCCCTATTTGCTATGATGGATTCGAACCATCAGGTAGAATGCAC
ATAGCATAAGGTATTATGAGAGCAATCAATGTAAATAAGCTTGTCGATGCAGGCTGTATT
TTCATTTTTTGGGTTGCTGACTGGTTCGCTTTACTTAACAATAAAATGGATGGTGATTTA
GATAAGATTAGAACAGTTGGTCGTTATTTTATTGAAACTTGGAAAGCTGCAGGAATGAAA
ATGCACAATGTTAAATTTTTATGGTGTTCTGACGAAATCAATAAGAAGTCAAACGATTAC
TGGCTTCAAGTCATAGATGTTGCTAGAAAGTTTAATATCACAAGAATGAAAAAATGTTCT
TAAATTATGGGAAGAGCCGAAAGTGATGAATTAGCTGTCTCCTAATTGTTATATCCTGCT
ATGTAATGCACAGATATCTTCCACTTAAAGGCTGACATTTGCTCTTTGGGTTTAGATTAA
CGTAAAGTTAATATGCTTGCAAGAGACTATGTTGCCAAGCCTGATAATAACTACAAACTT
CACACTCCTGTTATTGTTTCTCATCATATGCTTAGTGGTTTAAAAGAAGGATAAGCTAAA
ATGAGTAAAAGTGATCCTATGAGTGCAATTTTCATGGAAGATACTGAGGAAGATGTCAAC
AAAAAGATCGATGGTGCTTACTGCAAGCCCAAGGAAGTTTACTAAGAAGATGGTAAAACT
TTTGTTAATCCTATTATGGATTACACTAAAAGCATTGTATTTGGTGCTTTCAATAAAATT
GAACTTATCCGTAAACCCGAAAACGGTGGCAACATTACCTACAACACTTACGAATAACTT
GAACAAGATTACATTGAAGGAAAGGTACATCCTGGAGATTTGAAGGCTGCTGTTAAAATT
GCCCTTAACAAATTAATCCAACCTGTTCGTGATCATTTCTAGAATGACCCTGTTGCTAAG
CAACTATTATCTCAAATTAAATTATGGCAATAGTAGAAATTACAAAAAGAATAATAGTTG
TTGTTGCAATAATAAAAAGAAGCAGCTGCACAAGCTTAATGA

>TTHERM_00149980(gene)
ATGGATACAAAAATCAACTACTTGACTGGTGGATTGCAATTTAAGCTTCATGACGATATC
GAAGAAGAAGTAGTTTAGCTTAAATAAAATCTTTAAAGAATGTATAAACCAATAGCACCC
TCCGTAGATTTAAATGCTGCTTTTGACCCTTAACCCAGCAAGTATATATTAAATTATAAG
CATAAACGTTTAATAATTTTAAAAAGAAAAAATAACTAAAATTGCTAAAATTATTTCTCA
AATTACAAACTAAAATCATTTTAAGTGGACAATATTAATTTAAAAATTTTTATTAATAAT
AAAGGTTATCTTTGAAACAAAGATTCTAACTCATTAAGAGTTTTGCTGAAGAAATAATTC
AAGAAAATGAACTCGTAAAGTTATTATCTACAAAGCAATTCCCTATTTGCTATGATGGAT
TCGAACCATCAGGTAGAATGCACATAGCATAAGGTATTATGAGAGCAATCAATGTAAATA
AGCTTGTCGATGCAGGCTGTATTTTCATTTTTTGGGTTGCTGACTGGTTCGCTTTACTTA
ACAATAAAATGGATGGTAAATTTTTATAAAATACATGAAACCAAATAAACTATAAATCAA
ATGAAAAATCGATTGTTTTTATTTCCCTCAAGCTCATATTACTTTTATAAATTTAAGGTG
ATTTAGATAAGATTAGAACAGTTGGTCGTTATTTTATTGAAACTTGGAAAGCTGCAGGAA
TGGTAATAAGAATAAAAATAAAAAAGATTAATCTTTTTATTTAGTTTTTAGAGGAAAACA
AAGACAAATAAATTTTTTTAAATATCTTAGAAAATGCACAATGTTAAATTTTTATGGTGT
TCTGACGAAATCAATAAGAAGTCAAACGATTACTGGCTTCAAGTCATAGATGTTGCTAGA
AAGTTTAATATCACAAGAATGAAAAAATGTTCTTAAATTATGGGAAGAGCCGAAAGTGAT
GAATTAGCTGTCTCCTAATTGTTATATCCTGCTATGTAATGCACAGATATCTTCCACTTA
AAGGCTGACATTTGCTCTTTGGGTTTAGATTAACGTAAAGTTAATATGCTTGCAAGAGAC
TATGTTGCCAAGCCTGATAATAACTACAAACTTCACACTCCTGTTATTGTTTCTCATCGT
AATTAAAATATTTAAAATTTTTAAATAATAATTTTAAAATTAATATTCTGTTTTTGCAAC
CCACCCACATAAAAAATATAAACTTATCTAATATTCTAATCTTGTTTTTTTATTTAAATG
AATTAATTCTCTTAATCTAAAAATATAACTAAATTAACTTTTATATTTAGTAAATATGCT
TTAATTTTTAGATGAATTATATTTAATTTATCAAATAAAAATTTATCTTTTTTTGCTGAA
TATTTTTTTAAAATTAAGATATGCTTAGTGGTTTAAAAGAAGGATAAGCTAAAATGAGTA
AAAGTGATCCTATGAGTGCAATTTTCATGGAAGATACTGAGGAAGATGTCAACAAAAAGA
TCGATGGTGCTTACTGCAAGCCCAAGGAAGTTTACTAAGAAGATGGTAAAACTTTTGTTA
ATCCTATTATGGATTACACTAAAAGCATTGTATTTGGTGCTTTCAATAAAATTGAACTTA
TCCGTAAACCCGAAAACGGTGGCAACATGTAAATTATAAATAAATTTAGAGATATTTTAA
TCATATTATTATACATATAGTACCTACAACACTTACGAATAACTTGAACAAGATTACATT
GAAGGAAAGGTACATCCTGGAGATTTGAAGGCTGCTGTTAAAATTGCCCTTAACAAATTA
ATCCAACCTGTTCGTGATCATTTCTAGAATGACCCTGTTGCTAAGCAACTATTATCTCAA
ATTAAATTATGGCAATAGTAGAAATTACAAAAAGAATAATAGTTGTTGTTGCAATAATAA
AAAGAAGCAGCTGCACAAGCTTAATGA

>TTHERM_00149980(protein)
MDTKINYLTGGLQFKLHDDIEEEVVQLKQNLQRMYKPIAPSVDLNAAFDPQPSKLSLKQR
FQLIKSFAEEIIQENELVKLLSTKQFPICYDGFEPSGRMHIAQGIMRAINVNKLVDAGCI
FIFWVADWFALLNNKMDGDLDKIRTVGRYFIETWKAAGMKMHNVKFLWCSDEINKKSNDY
WLQVIDVARKFNITRMKKCSQIMGRAESDELAVSQLLYPAMQCTDIFHLKADICSLGLDQ
RKVNMLARDYVAKPDNNYKLHTPVIVSHHMLSGLKEGQAKMSKSDPMSAIFMEDTEEDVN
KKIDGAYCKPKEVYQEDGKTFVNPIMDYTKSIVFGAFNKIELIRKPENGGNITYNTYEQL
EQDYIEGKVHPGDLKAAVKIALNKLIQPVRDHFQNDPVAKQLLSQIKLWQQQKLQKEQQL
LLQQQKEAAAQAQ