Identifiers and Description

Gene Model Identifier

TTHERM_00181100

Standard Name

PUS3 (PseudoUridine Synthase 3)

Aliases

PreTt29828 | 14.m00395 | DEG1

Description

PUS3 tRNA pseudouridine synthase; tRNA pseudouridine synthase A family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• pseudouridine synthase activity (IEA) | GO:0009982
• RNA binding (IEA) | GO:0003723

Biological Process

• pseudouridine synthesis (IEA) | GO:0001522
• RNA modification (IEA) | GO:0009451

Domains

• ( PF01416 ) tRNA pseudouridine synthase
• ( TIGR00071 ) tRNA pseudouridine synthase A

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_09939.1	9.997093137033517e-262
	Description: tRNA pseudouridine synthase A family protein (498 aa)
DictyBase	DDB_G0288909	2.998830401637127e-79
	Description: pus3 on chromosome: 5 position 2110038 to 2111898
WormBase	WBGene00006473	7.002037867398653e-67
	Description: locus:tag-124 Probable tRNA pseudouridine synthase tag-124 status:Confirmed UniProt:Q09524 protein_id:CAA87378.1
Tetrahymena borealis	EI9_16728.1	7.002037867398653e-67
	Description: hypothetical protein (252 aa)
SGD	YFL001W	6.997942222381785e-66
	Description: DEG1 tRNA:pseudouridine synthase, introduces pseudouridines at position 38 or 39 in tRNA, important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm; non-essential for viability
Oxytricha	Contig18928.0.g26	1.9997677415930956e-65
	Description: tRNA pseudouridine synthase
Stentor Coeruleus	SteCoe_32353	1.603810890548638e-28
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00181100(coding)
ATGGATACAATTTAATAAAGCGAATAAGGAAATATACAAATATCTTAAGAAGGCCAAAGT
GAATAGAAAGCTAACTAAGATATTAAAAAAGATGAAGAGCAAAAAAGCGAGTCATTAGAA
AGTGAAGACTTAGATAAATTTTCTAAGGAAGAAATCATTAAAAAATATTTGTTCATAAAA
AAGGAAAATTAAGTTTTAAGAAAATAATTAAACCATAACAACGACACAAAAGCCCCTATT
CCTAATAATAGCTCTTAAAATGAGACTAAAAAGTAAAAGAAAGAGCAAAAATAGAATAAC
AAAAAGGAAAGCCTATTCGAAATCTACCAATAACAGCATTATGCCTTAAAAATGTCTTAT
GTTGGAATCAATTATCAAGGCTTAGCATATTAGTAAGAAACTGACAACACTGTAGAAGAA
TAGCTCTTCAAGGCACTTGAAAAGACAACACTGATAAAAAATAGAGATAATTGCAATTTC
ACACGTTCAGGAAGAACTGACAAAGGAGTTAGTGCTTTAGGATAAGTTATTGGTATCACT
CTTAGAACTTCAATAAAAATAGGTGAAAATATTGATGAAATAGAAAATAAATTAGATTAC
ATTAAGATGCTTAATAGTAATCTTCCAGACGACATAAGGATTTTAGGTTGTTCTAAAGTT
GATCCTGCTTTTAATGCAAGATTTGATTGTTAAAAGAGAATTTATAAGTATTACTTTTTT
GAGAATTAGATGGATATTTAAAGAATGAAGGAAGCAGCTAACCTCTTTTTGGGAGAACAC
GATTTTAGAAATTTCTGCAAAATAGATGTTTTGCAAACACTTAACTATGTTAGAATTATT
TATTAACTTGATATAGAAGAAGTTTAGGCTAATTTTGGTACTCTTGACCCTCGTTCTAAA
TTATATGTAGCAACTATTCAAGGAAGTGCTTTCCTTTGGCATTAAATCAGAAACATGATG
GCTATACTTTTTCTAGTAGGCAGAAAATAAGAAGAACCTTCAATAGTTACAGAGCTTCTT
GATATTTAAAAGAATCCATCTAAACCTAATTATGAGATGGCTCCTGATTATCCTCTAGTA
TTATTTGATTGCTTGTACAATAATGTTAGTTTTAACTACAGTAGCGATTAGATAAAGATT
TATGAACATTATTTGCAGATAATCTAAAAAAAGTGTATCGAAAATTAGCTTTATATTACA
ACTCTCAATTATATGGCATAAACTGCTTAGCAATTTAACAATTATAATCTTATTTAAAAT
TCATTGATTTCAGAAGAAGCTACTCTTCGTAATAAGAAATACTAGCATCTTTCAAAAAGA
TAATGTGCTTAATCATCAGAAGACACTTTAAAAAATTTAAAAGGCAGAAAATTAGATAAG
TTTTTAATTAAGCAAGAAAAATAGATAAATTATTAATAGTAGCGCGAAGCAGAAAAGAAT
TTATCATAAACATAAGATTAAACCTCTGAAGGAAACGATACTTAAGAATGA

>TTHERM_00181100(gene)
ATGGATACAATTTAATAAAGCGAATAAGGAAATATACAAATATCTTAAGAAGGCCAAAGT
GAATAGAAAGCTAACTAAGATATTAAAAAAGATGAAGAGCAAAAAAGCGAGTCATTAGAA
AGTGAAGACTTAGATAAATTTTCTAAGGAAGAAATCATTAAAAAATATTTGTTCATAAAA
AAGGAAAATTAAGTTTTAAGAAAATAATTAAACCATAACAACGACACAAAAGCCCCTATT
CCTAATAATAGCTCTTAAAATGAGACTAAAAAGTAAAAGAAAGAGCAAAAATAGAATAAC
AAAAAGGAAAGCCTATTCGAAATCTACCAATAACAGCATTATGCCTTAAAAATGTCTTAT
GTTGGAATCAATTATCAAGGCTTAGCATATTAGTAAGAAACTGACAACACTGTAGAAGAA
TAGCTCTTCAAGGCACTTGAAAAGACAACACTGATAAAAAATAGAGATAATTGCAATTTC
ACACGTTCAGGAAGAACTGACAAAGGAGTTAGTGCTTTAGGATAAGTTATTGGTATCACT
CTTAGAACTTCAATAAAAATAGGTGAAAATATTGATGAAATAGGTAATATTAATTAAGTT
AGTCTATATTATATATAAATATTTATTTATTATTTACTTTGATAGAAATAACAATTTTAA
AATATTTATTTTTTACAATGTGATAGAAAATAAATTAGATTACATTAAGATGCTTAATAG
TAATCTTCCAGACGACATAAGGATTTTAGGTTGTTCTAAAGTTGATCCTGCTTTTAATGC
AAGATTTGATTGTTAAAAGAGAATTTATAAGTATTACTTTTTTGAGAATTAGATGGATAT
TTAAAGAATGAAGGAAGCAGCTAACCTCTTTTTGGGAGAACACGATTTTAGAAATTTCTG
CAAAATAGATGTTTTGCAAACACTTAACTATGTTAGAATTATTTATTAACTTGATATAGA
AGAAGTTTAGGCTAATTTTGGTACTCTTGACCCTCGTTCTAAATTATATGTAGCAACTAT
TCAAGGAAGTGCTTTCCTTTGGCATTAAATCAGAAACATGATGGCTATACTTTTTCTAGT
AGGCAGAAAGTAATTATTTAGTTAGAAATTTAGTTTAAATACTTTATGAGTAATATTTAT
TATTTTAGATAAGAAGAACCTTCAATAGTTACAGAGCTTCTTGATATTTAAAAGAATCCA
TCTAAACCTAATTATGAGATGGCTCCTGATTATCCTCTAGTATTATTTGATTGCTTGTAC
AATAATGTTAGTTTTAACTACAGTAGCGATTAGATAAAGATTTATGAACATTATTTGCAG
ATAATCTAAAAAAAGTGTATCGAAAATTAGCTTTATATTACAACTCTCAATTATATGGCA
TAAACTGCTTAGCAATTTAACAATTATAATCTTATTTAAAATTCATTGATTTCAGAAGAA
GCTACTCTTCGTAATAAGAAATACTAGCATCTTTCAAAAAGATAATGTGCTTAATCATCA
GAAGACACTTTAAAAAATTTAAAAGGCAGAAAATTAGATAAGTTTTTAATTAAGCAAGAA
AAATAGATAAATTATTAATAGTAGCGCGAAGCAGAAAAGAATTTATCATAAACATAAGAT
TAAACCTCTGAAGGAAACGATACTTAAGAATGA

>TTHERM_00181100(protein)
MDTIQQSEQGNIQISQEGQSEQKANQDIKKDEEQKSESLESEDLDKFSKEEIIKKYLFIK
KENQVLRKQLNHNNDTKAPIPNNSSQNETKKQKKEQKQNNKKESLFEIYQQQHYALKMSY
VGINYQGLAYQQETDNTVEEQLFKALEKTTLIKNRDNCNFTRSGRTDKGVSALGQVIGIT
LRTSIKIGENIDEIENKLDYIKMLNSNLPDDIRILGCSKVDPAFNARFDCQKRIYKYYFF
ENQMDIQRMKEAANLFLGEHDFRNFCKIDVLQTLNYVRIIYQLDIEEVQANFGTLDPRSK
LYVATIQGSAFLWHQIRNMMAILFLVGRKQEEPSIVTELLDIQKNPSKPNYEMAPDYPLV
LFDCLYNNVSFNYSSDQIKIYEHYLQIIQKKCIENQLYITTLNYMAQTAQQFNNYNLIQN
SLISEEATLRNKKYQHLSKRQCAQSSEDTLKNLKGRKLDKFLIKQEKQINYQQQREAEKN
LSQTQDQTSEGNDTQE