Identifiers and Description

Gene Model Identifier

TTHERM_00190830

Standard Name

DRH1 (DExD/H box RNA helicase 1)

Aliases

PreTt08734 | 15.m00445 | 3697.m00156

Description

DRH1 DEAD/DEAH-box helicase; P68-like protein- putative

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• ATP-dependent helicase activity (IEA) | GO:0008026
• helicase activity (IEA) | GO:0004386
• nucleic acid binding (IEA) | GO:0003676

Domains

• ( PF00270 ) DEAD/DEAH box helicase
• ( PF00271 ) Helicase conserved C-terminal domain
• ( PF04851 ) Type III restriction enzyme, res subunit
• ( TIGR00614 ) ATP-dependent DNA helicase, RecQ family
• ( TIGR00643 ) ATP-dependent DNA helicase RecG
• ( TIGR01389 ) ATP-dependent DNA helicase RecQ
• ( TIGR01587 ) CRISPR-associated helicase Cas3

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

• ( SD01850 ) Macronucleus: Neo3 cassette replaces part of 5’ end of coding
• ( SD01851 ) Macronucleus: Neo3 cassette replaces part of 5’ end of coding
• ( SD01944 ) Micronucleus: neo4 Macronucleus: neo4
• ( SD01945 ) Micronucleus: Neo4 into 5’ end of coding of DRH1 Macronucleus: Neo4 into 5’ end of coding of DRH1
• ( SD02139 ) Micronucleus: Neo4 into 5’ end of coding of DRH1
• ( SD02140 ) Micronucleus: Neo4 into 5’ end of coding of DRH1
• ( SD02141 ) Micronucleus: Neo4 into 5’ end of coding of DRH1
• ( SD02142 ) Micronucleus: Neo4 into 5’ end of coding of DRH1
• ( SD02594 ) Macronucleus: Neo3 cassette replaces part of 5’ end of coding
• ( SD02595 ) Macronucleus: Neo3 cassette replaces part of 5' end of coding
• ( SD02596 ) Macronucleus: Neo3 cassette replaces part of 5’ end of coding
• ( SD02597 ) Macronucleus: Neo3 cassette replaces part of 5’ end of coding
• ( SD02598 ) Micronucleus: neo4 Macronucleus: neo4
• ( SD02599 ) Micronucleus: neo4 at 5’ end of coding, some coding remains Macronucleus: neo4 at 5’ end of coding, some coding remains

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_06214.1	9.997093137033517e-262
	Description: P68-like protein (718 aa)
Oxytricha	Contig21312.0.g80	6.002069467939404e-154
	Description: DEAD/DEAH box helicase
SGD	YNL112W	4.000899569014317e-153
	Description: DBP2 Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing
DictyBase	DDB_G0293168	9.003323285460187e-148
	Description: ddx17 on chromosome: 6 position 2360817 to 2364250
WormBase	WBGene00010260	2.0000211193600847e-137
	Description: locus:ddx-17 status:Confirmed UniProt:Q9XUW5 protein_id:CAB04518.1
WormBase	WBGene00002299	2.0000211193600847e-137
	Description: locus:let-23 status:Partially_confirmed UniProt:B5BM27 protein_id:CAR31509.1
Stentor Coeruleus	SteCoe_12603	5.96629836401057e-72
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:27793833: McDaniel SL, Zweifel E, Harris PK, Yao MC, Cole ES, Chalker DL (2016) DRH1, a p68-related RNA helicase gene, is required for chromosome breakage in Tetrahymena. Biology open 5(12):1790-1798

Sequences

>TTHERM_00190830(coding)
ATGATTAACTTATTAAAAATTAGTAGTAAGACTAAGTTAATTAGTAGTTTGAGCTCAAGT
GCTTCTGCATTTAAAATAATCAAACAAAATTCTGAAAATTTATAATTTCAAAAACTAATA
ACCAAATAATTATATCAAATGTCAAGATAAATCTAAAGCAATTCTAATAAGGGAGAAGGC
TCAGACTATGAGAGTCATCAAAGCTCCGACAACCAACAGAAATAAGGAAATGGCTACTTC
AATAACAGAAATGTCAATGGCCAAAATTAAAATGGCTACTAAAGCAATGGCTATAACAAT
AGAGGTGGATATCAAAAGAGCTACGGAACAAACAAGTACAATAACGGAAATGGCTATGGT
AACTCCAATGGTGGCTACTTCAATAACAACAATAAACCAAATGGATACTTCAATGCCAAT
AAAAAGTTTGGAAATGAAGAGCAAAAAACTAACGTAGATAATCAAAAACCTTACGGATAC
AACTAATAAAATAACAACTAGTCTAATAAGGACTTGAATAACAGCGGCTACAGTGATGAA
AATCACTTAGGTGAAAATTTACACGATATTGACTACACAAAGGTCGAGCTCAAGCCTTTC
TAAAAGGTTTTCTACTAAGTTGGTAAATCAATACATACTGATGAAGAAATTGCTACCTAC
TAAAGAGAGAAGGGTATTATAATCCGTTCAAAGCACAAAGAGGTTCCCTAACCTTTCATA
AAATGGAACGAAACCAAATTCCCCAAATATATTATGTCCGTAATAGAAGACAGCAAATTC
TCTGAACCTATGCCCATCTAAGCTCAGTCTTTCCCTATTGTGTTGAGTGGTCATGACTTG
ATAGGTATTGCTTAAACTGGTTCAGGAAAAACTCTTTCTTTCATGCTTCCTGCTCTTGTT
CATATTAATGCCCAAGATCCCGTAAAGCCAGGCGAAGGCCCTATTGCATTAGTTTTGGCT
CCAACCAGAGAATTGGCAAACTAAATATAAGAACAATGCTTCAAATTTGGCAGCAAATGC
AAAATTAGCAGTGTTTGTGTTTATGGTGGTGCCCCTAAGATTTACCAAGAAAAGGAACTC
CGTAATGGCTGCGATATTGTCATTGCTACTCCTGGTAGACTCATTGATTTCTTGGAAAGT
AATGTTATCGACTTGAAGAGAGTAACTTATCTTGTTCTCGATGAAGCCGATAGAATGCTT
GATATGGGTTTTGAACCTTCCATCAGAAAAATCGTTGGCTAAATCAGACCTGATAGATAA
ACTCTTATGTTCTCTGCTACTTGGCCTTAAACTGTTAGAAGACTTGCCCTTGATTTTTGT
CATGGAGATCCTATTCACATTCAAATTGGTGATATGGAAAACAACGTCAACAATGATATC
GATCAATAAGTTGAAATCATTGATAAAAGCCAAAAATACGATAGAGTTAAAGAAATTCTT
AGCACAATGACAAGATCTGATAAGACCATTATCTTTACTTAAACAAAGAAAGATTGTGAT
GATCTTAGCAAAGCTCTCTAAACTGACAATATAAGAAACATCTGTATCCATGGTGATAAA
TCCCAAAGAGATAGAGATAAAGTTATGGACCTCTTCAAAACTGGTAGAGTCAACACTTTA
ATTGCAACCGATGTTGCATCTAGAGGTCTTGATGTCAAGGACATTAAATTAGTTATTAAC
TATGATTTCCCTAAGCAAATCGAAGACTACGTACATAGAGTCGGTAGAACTGGAAGAGCA
GGTGCTTAAGGTAAAGCTATTTCATTCCTTGATCAATATGAAGACAAGAAGATTTCTAAG
GAATTAGTTGATGTCTTGAAGTAAAATAATTAAGAAATTAGTCAAGATCTTCTTGAACTC
TCTGAAGCAAACTACAAGGGTAATTACAGTAATAACTATAATAAGAACAGAAGTAGCAAG
CCTTACAGTGGTGGATACAATAATAACAGAAACTATTATGGAAATAATAACGAAATGGGT
TTCAGAAACAGCAATAATGGATTCTCTAACAATGGCTACCAAAATGGTAACAGCAACGGA
GGTTATAGAAGCCAATAGAACAATAATGGGTTCCAAAATAATAACTATAACCGTGACTTC
CCTAAGAGATAGGAAGATGGCAACGGTGGTTCTGAACAACCTAAGAAATTCGGTTTCTTC
AACCCAAAGAAAGACAACTGA

>TTHERM_00190830(gene)
ATGATTAACTTATTAAAAATTAGTAGTAAGACTAAGTTAATTAGTAGTTTGAGCTCAAGT
GCTTCTGCATTTAAAATAATCAAACAAAATTCTGAAAATTTATAATTTCAAAAACTAATA
ACCAAATAATTATATCAAATGTCAAGATAAATCTAAAGCAATTCTAATAAGGGAGAAGGC
TCAGACTATGAGAGTCATCAAAGCTCCGACAACCAACAGTAAGCATTTCAGTATTTTCTT
TCATAGCAACTTACATCCATAGCTTAAAATTTCATATTATGTCTAAGCTACTCCAAAGGA
AAACTAACTCTTTTTTACTAAGCAAGCTATGAAATCTTCATGATTTTAAAAATCTAAAAA
ATAAGGAGATATGAAAAAAAAATCAAGAATACATTCTCTAAAATAGTTTTTATCACAATA
AATTCCAATGATTTCATCTATAATTTAGAATTAACAACAGAAAATCTATCTAATTTAAGC
AGTTGGATGAAGAGTTTTTTGTTTGGAGCAGATATTTTGCTTTTTATTTTCTGACAAAAC
CATTCATTAACACAATATTATAAATTATAAAGGAAATAAGGAAATGGCTACTTCAATAAC
AGAAATGTCAATGGCCAAAATTAAAATGGCTACTAAAGCAATGGCTATAACAATAGAGGT
GGATATCAAAAGAGCTACGGAACAAACAAGTACAATAACGGAAATGGCTATGGTAACTCC
AATGGTGGCTACTTCAATAACAACAATAAACCAAATGGATACTTCAATGCCAATAAAAAG
TTTGGAAATGAAGAGCAAAAAACTAACGTAGATAATCAAAAACCTTACGGATACAACTAA
TAAAATAACAACTAGTCTAATAAGGACTTGAATAACAGCGGCTACAGTGATGAAAATCAC
TTAGGTGAAAATTTACACGATATTGACTACACAAAGGTCGAGCTCAAGCCTTTCTAAAAG
GTTTTCTACTAAGTTGGTAAATCAATACATACTGATGAAGAAATTGCTACCTACTAAAGA
GAGAAGGGTATTATAATCCGTTCAAAGCACAAAGAGGTTCCCTAACCTTTCATAAAATGG
AACGAAACCAAATTCCCCAAATATATTATGTCCGTAATAGAAGACAGCAAATTCTCTGAA
CCTATGCCCATCTAAGCTCAGTGTAAATATTTTTATAAATTGAATTTCTTTCTCTATGAC
ATTAGTTTGATAGACACTTGAAAATTTTTGTCAAGATGTTACAAACAAGAAATAGAAGAA
AAAGTATAAAATGTATGAATGTTCCTTCATACGTACTACGATAATTAAATGAATCAAAAT
TTGATTTAAATTGCAATGAAATTAAATCATTCAAACAAACTACGCTCATAAGTGATTAAA
TAAATGAGTATTTTATCTTTGATTTTATTAATTAGTCACTAAATTTATCTATGACTCACT
TAATCAATCAATCAATCGCTTAGAGAAAATTTTTTATCTCCCACCTTTAAATAAATAAAT
AATTAGCGTGTTAGATAAAAATTGATTTCAAACACAAATAAATCATATTTCCAATATTTA
ATTTTTCCTCTGAAAATTAATAATTTTGCATTCTCTTTATTTTCAAATTAATTATTTTAT
ATGCATTAATTATGAAACTAAGAAAATTGAATATGTAGCTAAATTTTCTTTTTCCCAACT
ACAAATTAATTAATTAATTAATTAAATTTTAAAACCCATTTTATACATCCCATTTTTTTG
ACAGATTTAAATATTTTTGATACTAAAATTAGTATTTTAATATATTTGTTTATTCATTCA
TAAATTAATTAATAATCACTCTATAATATAGCTTTCCCTATTGTGTTGAGTGGTCATGAC
TTGATAGGTATTGCTTAAACTGGTTCAGGAAAAACTCTTTCTTTCATGCTTCCTGCTCTT
GTTCATATTAATGCCCAAGATCCCGTAAAGCCAGGCGAAGGCCCTATTGCATTAGTTTTG
GCTCCAACCAGAGAATTGGCAAACTAAATATAAGAACAATGCTTCAAATTTGGCAGCAAA
TGCAAAATTAGCAGTGTTTGTGTTTATGGTGGTGCCCCTAAGATTTACCAAGAAAAGGAA
CTCCGTAATGGCTGCGATATTGTCATTGCTACTCCTGGTAGACTCATTGATTTCTTGGAA
AGTAATGTTATCGACTTGAAGAGAGTAACTTATCTTGTTCTCGATGAAGCCGATAGAATG
CTTGATATGGGTTTTGAACCTTCCATCAGAAAAATCGTTGGCTAAATCAGACCTGATAGA
TAAACTCTTATGTTCTCTGCTACTTGGCCTTAAACTGTTAGAAGACTTGCCCTTGATTTT
TGTCATGGAGATCCTATTCACATTCAAATTGGTGATATGGAAAACAACGTCAACAATGAT
ATCGATCAATAAGTTGAAATCATTGATAAAAGCCAAAAATACGATAGGTAAATAATAATT
ATTACTTAAATTTGACACATTATAATATCTAATTTATCATAAAGAGTTAAAGAAATTCTT
AGCACAATGACAAGATCTGATAAGACCATTATCTTTACTTAAACAAAGAAAGATTGTGAT
GATCTTAGCAAAGCTCTCTAAACTGACAATATAAGAAACATCTGTATCCATGGTGATAAA
TCCCAAAGAGATAGAGATAAAGTTATGGACCTCTTCAAAACTGGTAGAGTCAACACTTTA
ATTGCAACCGATGTTGCATCTAGAGGTCTTGATGTCAAGGACATTAAATTAGTTATTAAC
TATGATTTCCCTAAGCAAATCGAAGACTACGTACATAGAGTCGGTAGAACTGGAAGAGCA
GGTGCTTAAGGTAAAGCTATTTCATTCCTTGATCAATATGAAGACAAGAAGATTTCTAAG
GAATTAGTTGATGTCTTGAAGTAAAATAATTAAGAAATTAGTCAAGATCTTCTTGAACTC
TCTGAAGCAAGTAATTAATAACTTTAATTAATTTTCACCATCATTTATATTTATTTTCAC
AATTGAAAAGTTAAATATTTATTTATTCATATATTTTCCTCTAAAAAAAAAGACTACAAG
GGTAATTACAGTAATAACTATAATAAGAACAGAAGTAGCAAGCCTTACAGTGGTGGATAC
AATAATAACAGAAACTATTATGGAAATAATAACGAAATGGGTTTCAGAAACAGCAATAAT
GGATTCTCTAACAATGGCTACCAAAATGGTAACAGCAACGGAGGTTATAGAAGCCAATAG
AACAATAATGGGTTCCAAAATAATAACTATAACCGTGACTTCCCTAAGAGATAGGAAGAT
GGCAACGGTGGTTCTGAACAACCTAAGAAATTCGGTTTCTTCAACCCAAAGAAAGACAAC
TGA

>TTHERM_00190830(protein)
MINLLKISSKTKLISSLSSSASAFKIIKQNSENLQFQKLITKQLYQMSRQIQSNSNKGEG
SDYESHQSSDNQQKQGNGYFNNRNVNGQNQNGYQSNGYNNRGGYQKSYGTNKYNNGNGYG
NSNGGYFNNNNKPNGYFNANKKFGNEEQKTNVDNQKPYGYNQQNNNQSNKDLNNSGYSDE
NHLGENLHDIDYTKVELKPFQKVFYQVGKSIHTDEEIATYQREKGIIIRSKHKEVPQPFI
KWNETKFPKYIMSVIEDSKFSEPMPIQAQSFPIVLSGHDLIGIAQTGSGKTLSFMLPALV
HINAQDPVKPGEGPIALVLAPTRELANQIQEQCFKFGSKCKISSVCVYGGAPKIYQEKEL
RNGCDIVIATPGRLIDFLESNVIDLKRVTYLVLDEADRMLDMGFEPSIRKIVGQIRPDRQ
TLMFSATWPQTVRRLALDFCHGDPIHIQIGDMENNVNNDIDQQVEIIDKSQKYDRVKEIL
STMTRSDKTIIFTQTKKDCDDLSKALQTDNIRNICIHGDKSQRDRDKVMDLFKTGRVNTL
IATDVASRGLDVKDIKLVINYDFPKQIEDYVHRVGRTGRAGAQGKAISFLDQYEDKKISK
ELVDVLKQNNQEISQDLLELSEANYKGNYSNNYNKNRSSKPYSGGYNNNRNYYGNNNEMG
FRNSNNGFSNNGYQNGNSNGGYRSQQNNNGFQNNNYNRDFPKRQEDGNGGSEQPKKFGFF
NPKKDN