Identifiers and Description

Gene Model Identifier

TTHERM_00190950

Standard Name

ACT1 (ACTin 1)

Aliases

actin | PreTt08746 | 15.m00457 | 3697.m00168 | g14052

Description

ACT1 macronuclear actin; monomeric subunits of the actin protein (G-actin) polymerize to form structural filiaments (F-actin); localized to the cleavage forrow during cytokinesis; Actin family

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• actin filament (TAS) | GO:0005884
• actomyosin contractile ring (IDA) | GO:0005826
• cleavage furrow (IDA) | GO:0032154
• cytoproct (IDA) | GO:0031911
• microtubule basal body (IDA) | GO:0005932
• phagocytic vesicle (IDA) | GO:0045335

Biological Process

• cilium or flagellum-dependent cell motility (IMP) | GO:0001539
• cytokinesis (IMP) | GO:0000910
• exocytosis (IEP) | GO:0006887
• phagocytosis (IMP) | GO:0006909

Domains

• ( PF00022 ) Actin

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

• ( SD01796 ) ACT1 KO homozygous in mic, heterokaryon
• ( SD01797 ) ACT1 with neo3 inserted at Sfu1 site
• ( SD01798 ) ACT1 with neo3 inserted at Sfu1 site

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16524910: Williams NE, Tsao CC, Bowen J, Hehman GL, Williams RJ, Frankel J (2006) The actin gene ACT1 is required for phagocytosis, motility, and cell separation of Tetrahymena thermophila. Eukaryotic cell 5(3):555-67
2. Ref:16593729: Cupples CG, Pearlman RE (1986) Isolation and characterization of the actin gene from Tetrahymena thermophila. Proceedings of the National Academy of Sciences of the United States of America 83(14):5160-4

Sequences

>TTHERM_00190950(coding)
ATGGCTGAAAGTGAATCCCCCGCTATTGTTATTGATAACGGTTCCGGTATGTGCAAGGCT
GGTATTGCTGGTGACGATGCTCCCAGAGCCGCCTTCCCCTCCATTGTCGGTAGACCCAAA
ATGCCTGGTATCATGGTCGGTATGGATCAAAAGGAATGCTACGTTGGTGAAGAAGCCCAA
GCCAAGAGAGGTGTTTTGAATTTGAAATATCCCATTGAACACGGTATTGTCACCGATTAC
GATGATATGGAAAAGATCTGGCATCACTGCTTCTACAATGAACTCAGAGTTACCCCTGAA
GAACACCCCTGCTTACTTACTGAAGCTCCCCAAAACCCCAAGTTGAACAGAGAAAAGATG
ACCAAGACCATGTTCGAAACTTTCAACGTTCCCTCCTTCTACGTTGCCATCCAAGCCGTT
CTTTCCCTCTACGCTTCCGGTAGAACCACTGGTATCGTCGTTGACTCTGGTGATGGTGTT
ACCCACACTGTTCCCATCTATGAAGGTTACGCTCTTCCTCACGCCATCTTGAGAATCGAT
TTGGCTGGTAGAGACTTAACTGAATACTGCATGAAGCTCCTCTACGAAATTGGTTTGAAC
TTCTCTTCCACTGCCGAAAGAGAAATCATCAGAGATATCAAGGAAAAGCTCTGCTACGTC
GCTATCGACTACGAAGCTGAATTAAAGGCTTACAAGGAATCCTCCTAAAACGATAAATCT
TACGAATTACCCGATGGTAACACCATTACCGTCCAAGACTAGAGATTCAGATGCCCTGAA
CTCCTCTTCAAGCCTGCCTTCATCGGTAAGGAATTCCCTGGTATCCACGAACTTACCTTC
AACTCTATCATGAAGTGTGATGTCGATGTCAGAAAGGATCTTTACAACAACATCGTCCTC
TCTGGTGGTACCACTATGTTCCCTGGTATTGCTGAAAGACTTTCTAAGGAAGTTAGCGCT
CTTGCTCCTTCTTCCATGAAGATTAAGGTTGTTGCTCCTCCTGAGAGAAGATACTCTGTC
TGGATTGGTGGTTCCATTCTTTCCTCTCTTTCTACCTTCCAAACTATGTGGATTACTAAG
GCTGAATATGATGAATCTGGTCCTTCCATCGTCCACAGAAAGTGCTTCTGA

>TTHERM_00190950(gene)
CATCAAACAAATTAAGAATTATATTTAGATAAGCAATAATTAATTGACTGATGAGAAATT
TAATTGATATTAGTGATTGCTAGTGATAAGAAAGAGGTGGGAGGTACTTTAAAATTAACA
GGAATATTATCTGAAGTACTATATAAATAAATTTTATAAAATAAAATAAAAGATATCCTT
TTTTCCAAAAGAAAAAAAAGAATAATTAAATAAAGACAACATAAAAACTAGATAAAGTAA
AATGGCTGAAAGTGAATCCCCCGCTATTGTTATTGATAACGGTTCCGGTATGTGCAAGGC
TGGTATTGCTGGTGACGATGCTCCCAGAGCCGCCTTCCCCTCCATTGTCGGTAGACCCAA
AATGCCTGGTATCATGGTCGGTATGGATCAAAAGGAATGCTACGTTGGTGAAGAAGCCCA
AGCCAAGAGAGGTGTTTTGAATTTGAAATATCCCATTGAACACGGTATTGTCACCGATTA
CGATGATATGGAAAAGATCTGGCATCACTGCTTCTACAATGAACTCAGAGTTACCCCTGA
AGAACACCCCTGCTTACTTACTGAAGCTCCCCAAAACCCCAAGTTGAACAGAGAAAAGAT
GACCAAGACCATGTTCGAAACTTTCAACGTTCCCTCCTTCTACGTTGCCATCCAAGCCGT
TCTTTCCCTCTACGCTTCCGGTAGAACCACTGGTATCGTCGTTGACTCTGGTGATGGTGT
TACCCACACTGTTCCCATCTATGAAGGTTACGCTCTTCCTCACGCCATCTTGAGAATCGA
TTTGGCTGGTAGAGACTTAACTGAATACTGCATGAAGCTCCTCTACGAAATTGGTTTGAA
CTTCTCTTCCACTGCCGAAAGAGAAATCATCAGAGATATCAAGGAAAAGCTCTGCTACGT
CGCTATCGACTACGAAGCTGAATTAAAGGCTTACAAGGAATCCTCCTAAAACGATAAATC
TTACGAATTACCCGATGGTAACACCATTACCGTCCAAGACTAGAGATTCAGATGCCCTGA
ACTCCTCTTCAAGCCTGCCTTCATCGGTAAGGAATTCCCTGGTATCCACGAACTTACCTT
CAACTCTATCATGAAGTGTGATGTCGATGTCAGAAAGGATCTTTACAACAACATCGTCCT
CTCTGGTGGTACCACTATGTTCCCTGGTATTGCTGAAAGACTTTCTAAGGAAGTTAGCGC
TCTTGCTCCTTCTTCCATGAAGATTAAGGTTGTTGCTCCTCCTGAGAGAAGATACTCTGT
CTGGATTGGTGGTTCCATTCTTTCCTCTCTTTCTACCTTCCAAACTATGTGGATTACTAA
GGCTGAATATGATGAATCTGGTCCTTCCATCGTCCACAGAAAGTGCTTCTGATCAATTTA
AATTTAAACAAATCTATTTTATTTTAAGCTTAATTTTTCTATTAAATGCGTATAGTTGTT
ACAAACTTTTTTGTGTAGTGTTATTAATCTTCCATAATCTATTCCAAAAAAGATTCCACT
TCATCATTTCCATTCATTATTATATCCGACATA

>TTHERM_00190950(protein)
MAESESPAIVIDNGSGMCKAGIAGDDAPRAAFPSIVGRPKMPGIMVGMDQKECYVGEEAQ
AKRGVLNLKYPIEHGIVTDYDDMEKIWHHCFYNELRVTPEEHPCLLTEAPQNPKLNREKM
TKTMFETFNVPSFYVAIQAVLSLYASGRTTGIVVDSGDGVTHTVPIYEGYALPHAILRID
LAGRDLTEYCMKLLYEIGLNFSSTAEREIIRDIKEKLCYVAIDYEAELKAYKESSQNDKS
YELPDGNTITVQDQRFRCPELLFKPAFIGKEFPGIHELTFNSIMKCDVDVRKDLYNNIVL
SGGTTMFPGIAERLSKEVSALAPSSMKIKVVAPPERRYSVWIGGSILSSLSTFQTMWITK
AEYDESGPSIVHRKCF