Identifiers and Description

Gene Model Identifier

TTHERM_00193390

Standard Name

LIA7 (localized in macronuclear anlagen 7)

Aliases

PreTt06622 | 16.m00278

Description

cyclin-dependent kinase-like Serine/Threonine kinase family protein; Protein kinase domain containing protein. Sequence similarity to the STE11 protein kinase family (Eisen et al.- 2006).

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) Protein kinase domain
• ( PF06293 ) Lipopolysaccharide kinase (Kdo/WaaP) family
• ( PF07714 ) Protein tyrosine and serine/threonine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_03618.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (787 aa)
Oxytricha	Contig11718.0.g18	2.999564368270328e-76
	Description: Protein kinase domain
DictyBase	DDB_G0283265	3.001032840497736e-70
	Description: mkkA on chromosome: 4 position 530684 to 534789
SGD	YJL095W	2.0008958828286524e-54
	Description: BCK1 Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p
WormBase	WBGene00001526	1.9991939848149086e-44
	Description: locus:gck-1 status:Partially_confirmed UniProt:H2L0A0 protein_id:CCD72151.2
WormBase	WBGene00012375	1.9991939848149086e-44
	Description: locus:mecr-1 Probable trans-2-enoyl-CoA reductase 1, mitochondrial status:Confirmed UniProt:O45903 protein_id:CAB04958.1
Stentor Coeruleus	SteCoe_24084	3.0144087850653746e-40
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:17519286: Yao MC, Yao CH, Halasz LM, Fuller P, Rexer CH, Wang SH, Jain R, Coyne RS, Chalker DL (2007) Identification of novel chromatin-associated proteins involved in programmed genome rearrangements in Tetrahymena. Journal of cell science 120(Pt 12):1978-89

Sequences

>TTHERM_00193390(coding)
ATGACTTTGTTATTTTGGTAAATTTAGATAAAGAAATAACAATTCTTGATAGATAATTTA
TAAAATTACTTAATAAACTAGTTTCAATATGGTAAATTGAATATAAATAATACACTAGAT
AATAGTATATTAAGGTAGAGGAACCAATTAAAAACTTGTAGAGTTGAATCTTTAAAGAAA
AACAATACAAGAAAAGAAACACCTAGCATACCAATTTAGTATAAAGTACTGTACCTATTT
ATAGAGTCTTTTAGATAAAATAGCAAATTAGTATATAATATAGTTGGATTGCTATCACTA
TTATTTTAGCAATAAATAAATAATTAGGATTCGGACTGGTTTAAAGAAATGAGCATGTTT
GATAAAGAATATGATAAAAAAGGATTTGATATAAAATAGATTTAAAGTCCAATATTGAAA
TTATATCAAAATGCCAAGTAGGAAATTAATAATAAAAGCGATAATATATTTTCTCCAAGC
CTCAACTCGTAAAATATCCAATCATCTAAGAAAATATATTAACATTAGCTATAACCGCTT
TAATTGGTTTAGAAAGATGATTAAAAGGAACACAAAAAGAAGCCTCAATCAATTTAGTCA
AGTGCATATGGTCGAGTTTATAAAGGATTTGTCAAGAGTACTGGAAAATTTATTGCAATA
AAAGAAATGAAAGAAGAAATGATGTTAGGAGAAGATGCTCACTCTTTATTAGAAAGCATT
TGCAAAGAGATTTAATTGCTGAAGTAGCTTTCTCATAAAAATATAGTAAACTACATTGGA
TCAAAAAAGCAAGAAGGTAGTGTGTATATTTACATGGAATATATGCCAGGAGGATCAATA
TCTGAAATGCTGAAAAAGTATGGAGGATTTGATGAAGAAGTTATTTAAAAATTTGTTAAA
CAGTTACTTGAAGGTTTAATTTATCTACATTCAAAAGGAGTTATTCATCGAGATTTAAAA
GGAGCAAATATTTTATCTGATGGTTAAGGCAATGTGAAGTTAGCAGATTTTGGAGCTGCT
AGAAATATAGAAAATATTTTGTAGCATTCTCTATCATAGTCAGAATTTTGCAATTCTATA
AAAGGATCCCTTTATTGGATGGCTCCAGAATTAATTAAAAATGAAAAACATGGAAGAAGA
ATAGATGTTTGGAGCTTGGGCTGTACTGTAATTGAAATGGCATCTGCTTAGCATCCATGG
GAAAACATTAAAAAATTCTCAGATTTAGCAAATGCTGTGATAGAATAATAACCCATACCA
ATACCTTAGCATTTGAGTGAAGAATGCAAAGATTTTATCTCGAAATGCTGCACTTATGAT
AAAAAAATGAGACCAAAATCTCAATAACTTTTTAATCACCCTTTTCTATAAAAAAAATAC
TCCTGA

>TTHERM_00193390(gene)
ATGACTTTGTTATTTTGGTAAATTTAGATAAAGAAATAACAATTCTTGATAGATAATTTA
TAAAATTACTTAATAAACTAGTTTCAATATGGTAAATTGAATATAAATAATACACTAGAT
AATAGTATATTAAGGTAGAGGGTAAAAATTTAGGATTTTTTAATTATTCATTTAATTTCT
AAAAATTTATATTATTTTTAATATGCATTAATATAATATTTATTTATATATTAGAACCAA
TTAAAAACTTGTAGAGTTGAATCTTTAAAGAAAAACAATACAAGAAAAGAAACACCTAGC
ATACCAATTTAGTATAAAGTACTGTACCTATTTATAGAGTCTTTTAGATAAAATAGCAAA
TTAGTATATAATATAGTTGGATTGCTATCACTATTATTTTAGCAATAAATAAATAATTAG
GATTCGGACTGGTTTAAAGAAATGAGCATGTTTGATAAAGAATATGATAAAAAAGGATTT
GATATAAAATAGATTTAAAGTCCAATATTGAAATTATATCAAAATGCCAAGTAGGAAATT
AATAATAAAAGCGATAATATATTTTCTCCAAGCCTCAACTCGTAAAATATCCAATCATCT
AAGAAAAGTAAGCATAGTATTTATTATAATTCAAGTTGCACATTTAATTTAATAATTTAA
TCCAACATAATCAATTGTTCTCATCAAAAAATTAATTTTGCAAGAAAGAAAGGGAAAATT
TTTAAAAAGCAATAAAGTCAACTAACATTAACTCTTTTTTTGCAGTATATTAACATTAGC
TATAACCGCTTTAATTGGTTTAGAAAGATGATTAAAAGGAACACAAAAAGAAGCCTCAAT
CAATTTAGTCAAGTAAGCTTTAAACTTAAAAAAAATAATATTTTCAAAATTGTTTTCACT
TTTGATTCTATTAATATATGAATGATTATGCGGTTCATATAATTTCTAAAATTAGCAATT
AATTATTTTAAATTATAAAATTTGATAAAAAGGTGATCGAATCCTTTCAAAGGACTACTC
TAAAGGGAAAATTTTTTAAATTTAAAAAGATGAAATGAGTGGGTTTGCTATTAACAACTT
TAACAATAACAATAAATTAAGTGCCTTCCAAAGCTATCCATAATCACCCACTTACAAAGA
CTAATTTAATTGTAAATTGTAGAGTAAACAAAGTGAAGAGACTCCGACTTAAAAATCTTA
AAATTAACCTTTATATAGATTACCTAATAATGAAGCTAATCCTTTTAAGGATGGAAATTA
ATTGTAAATTTAGAATGATAATATAAAAGCTATAAAATTAGAAAGCGATTAGAAATCCAT
TTCTTAGCTTTAAAGTCCTAGAGTAAGGATTAAAACAATATAAAAAAATATGAAATCCCC
CACATATTAAAATCTAAACAAAGAAAAATTAAGTTAAAATGATTTAGCTGACTTTGAAAA
TTAGCAAAATTAAAATGGAGAGAAAATAAAAACAGAATAAAACAAAATAGATAACGAAGG
TCAATTTTAAGTCTAAAATGAGGAAGAACAAATATCACCAATAAAAAACAAAATTAATAA
AATTTAATCCATAAATGCTATTATACCAGAAAAATACCTCCCTAAGACACCATCGGGAGA
AAAATTTCATTAGAAATAGGAAAGTTCACGCCCAAGTTCAGGGAGAAATTAAAATTTTAT
TATAAAAATGGTCAATAATCACAATTATTCAGATGTCAATCATATACATAATAACAATTT
AAATAATGCAAATAATGGATCAAATACTGTTATAAGACTTTAGTCAAAAGAAATAAGTGA
TACACCCAAAAGCTAAAATAGAGAAGAAAAGTATTAAGAATCTTATAATGAAATTAAGGA
TAGAATCGACACCCAAAATTCATAATAAATAGGTGATTCTTTGTAAAATTTAGATGAAGA
ATAAAAAAAACGAAAAGCAAATTAGTGAACAAAAATAAAATAAACCTAATTCTAATTAGA
ATATATCTTCAAAAATATAATCCCTTAATTATATAAATGAAGAGAGAGAATTAGATTCAT
CTCCCATAGAATAAGGTTAAAATAGTAAACTGAAAGATAAAAATAATGATAAATAAAATA
TTATCAAAGAGTAATCATAAAATTAAAGATAAGAATCATCCATGATGTTACAAACAGCTT
CTGAAAAAAAAGAAATTAACAATTTAAAATATATTATTGAATCAAACAATTTAAATTAGA
ATAATAACAATAGCAGCAGCAATGATTATTTGGACGCATAAGTTGGGGAGTTAATTGGAT
AAGGTAAAATAGTAAATCAGATTTATTTAATTTTGGACAAATAAATTATTCAAAAGGTGC
ATATGGTCGAGTTTATAAAGGATTTGTCAAGAGTACTGGAAAATTTATTGCAATAAAAGA
AATGAAAGAAGAAATGATGTTAGGAGAAGATGCTCACTCTTTATTAGAAAGCATTTGCAA
AGAGATTTAATTGCTGAAGTAGCTTTCTCATAAAAATATAGTAAACTACATTGGATCAAA
AAAGCAAGAAGGTAGTGTGTATATTTACATGGAATATATGCCAGGAGGATCAATATCTGA
AATGCTGAAAAAGTATGGAGGATTTGATGAAGAAGTTATTTAAAAATTTGTTAAACAGTT
ACTTGAAGGTTTAATTTATCTACATTCAAAAGGAGTTATTCATCGAGATTTAAAAGTAAA
TATTACATTTAAACTTAAACAAATTTCAAATATTTATCTATTTATTTTAGGGAGCAAATA
TTTTATCTGATGGTTAAGGCAATGTGAAGTTAGCAGATTTTGGAGCTGCTAGAAATATAG
AAAATATTTTGTAGCATTCTCTATCATAGTCAGAATTTTGCAATTCTATAAAAGGGTAAA
ATAAATTTTATAAATTATTCTTTATCTTCAATTTAAACTAAAAAACTAAGAAATAATCAT
TTTACTGTTCTGAATTAAGTTTAAAACAAAATAATAAATAAAAAATGAAATATGATGTTA
TGAATTATTTGATAAAATATATTTATAATTCAAATTTAATGATAATAAAATTTTTAATTT
AGATCCCTTTATTGGATGGCTCCAGAATTAATTAAAAATGAAAAACATGGAAGAAGAATA
GATGTTTGGAGCTTGGGCTGTACTGTAATTGAAATGGCATCTGCTTAGCATCCATGGTAA
ATAAATTAATGTTAATAACTTAAATTGAAAATACATTGTTTATTAAATTAAATAAAGGGA
AAACATTAAAAAATTCTCAGATTTAGCAAATGCTGTGATAGAATAATAACCCATACCAAT
ACCTTAGCATTTGAGTGAAGAATGCAAAGATTTTATCTCGAAATGCTGCACTTATGATAA
AAAAATGAGACCAAAATCTCAATAACTTTTTAATCACCCTTTTCTATAAAAAAAATACTC
CTGA

>TTHERM_00193390(protein)
MTLLFWQIQIKKQQFLIDNLQNYLINQFQYGKLNINNTLDNSILRQRNQLKTCRVESLKK
NNTRKETPSIPIQYKVLYLFIESFRQNSKLVYNIVGLLSLLFQQQINNQDSDWFKEMSMF
DKEYDKKGFDIKQIQSPILKLYQNAKQEINNKSDNIFSPSLNSQNIQSSKKIYQHQLQPL
QLVQKDDQKEHKKKPQSIQSSAYGRVYKGFVKSTGKFIAIKEMKEEMMLGEDAHSLLESI
CKEIQLLKQLSHKNIVNYIGSKKQEGSVYIYMEYMPGGSISEMLKKYGGFDEEVIQKFVK
QLLEGLIYLHSKGVIHRDLKGANILSDGQGNVKLADFGAARNIENILQHSLSQSEFCNSI
KGSLYWMAPELIKNEKHGRRIDVWSLGCTVIEMASAQHPWENIKKFSDLANAVIEQQPIP
IPQHLSEECKDFISKCCTYDKKMRPKSQQLFNHPFLQKKYS