Identifiers and Description

Gene Model Identifier

TTHERM_00196590

Standard Name

CYC1 (CYClin 1)

Aliases

PreTt06844 | 16.m00500

Description

CYC1 amine-terminal domain cyclin; Cyclin; N-terminal domain containing protein; putative mitotic cyclin; similar to paramecium CYC1 and CYC2; involved in DNA replication and/or spindle assembly; expressed during conjugation

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

  • regulation of cyclin-dependent protein serine/threonine kinase activity (ISS) | GO:0000079

Domains

  • ( PF00134 ) Cyclin, N-terminal domain
  • ( PF02984 ) Cyclin, C-terminal domain
  • ( PF04947 ) Poxvirus Late Transcription Factor VLTF3 like
  • ( PF05867 ) Protein of unknown function (DUF851)
  • ( PF08613 ) Cyclin
  • ( TIGR01215 ) cell division topological specificity factor

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_03829.1 9.997093137033517e-262
Description: cyclin domain-containing protein (435 aa)
WormBase WBGene00002215 9.997093137033517e-262
Description: locus:klc-2 Kinesin light chain status:Confirmed UniProt:P46822 protein_id:CCD65113.1
Oxytricha Contig19213.0.g10 1.999469658314961e-75
Description: Cyclin, N-terminal domain
DictyBase DDB_G0275493 4.000904604388404e-59
Description: cycB on chromosome: 2 position 6000211 to 6001649
SGD YPR119W 9.997441244797434e-45
Description: CLB2 B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
WormBase WBGene00000868 2.9986404383886433e-43
Description: locus:cyb-3 G2/mitotic-specific cyclin-B3 status:Confirmed UniProt:Q10654 protein_id:CAB03311.2
Stentor Coeruleus SteCoe_32735 3.6251409191435593e-34
Description: None

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:27192402: Yan GX, Dang H, Tian M, Zhang J, Shodhan A, Ning YZ, Xiong J, Miao W (2016) Cyc17, a meiosis-specific cyclin, is essential for anaphase initiation and chromosome segregation in Tetrahymena thermophila. Cell cycle (Georgetown, Tex.) 15(14):1855-64
  2. Ref:12736907: Kovács P, Pállinger E (2003) Effects of indomethacin on the divisional morphogenesis and cytoskeleton-dependent processes of Tetrahymena. Cell biochemistry and function 21(2):169-75
  3. Ref:12183062: Zhang H, Huang X, Tang L, Zhang QJ, Frankel J, Berger JD (2002) A cyclin-dependent protein kinase homologue associated with the basal body domains in the ciliate Tetrahymena thermophila. Biochimica et biophysica acta 1591(1-3):119-128
  4. Ref:11596915: Berger JD (2001) Riding the ciliate cell cycle--a thirty-five-year prospective. The Journal of eukaryotic microbiology 48(5):505-18
  5. Ref:10568031: Zhang H, Adl SM, Berger JD (2000) Two distinct classes of mitotic cyclin homologues, Cyc1 and Cyc2, are involved in cell cycle regulation in the ciliate Paramecium tetraurelia. The Journal of eukaryotic microbiology 46(6):585-96

Sequences 

>TTHERM_00196590(coding)
ATGGCTTGCCTACAAATGAGAAATGGTGAATAATCCATGTTTGGAGACTCAAACAAATTA
TAAAGCAATCAACTTCGTGCTTTCGGGCGTGAGATTCAAAATATCCCTGACAGTCGCTTT
AATACAAGATCTTAATCAATAAAAGCAAACATGTAGCCTCACCACGCCTAAAAGCTTAGC
ATGGAATTAGATACAAATATAAATGAATAAGAGAACGGAATGAAAAGAAGTTCTCCTAGA
AAATTTTCAATGCATGTGAAGCATTCCTCCGAAGTTCCATAAAACCATTAAAAGAGAATG
TCAAGCTAAATTGACACTGTAAGCAATAATGGAACAGAGCGCTCATATTAAACCAATTAA
ACTGGCCTTTAAAATAAAAATATTGACATGAAAAATATAGAATTTGAATTGAATAGGATT
TCTAAGGAAGACTCTGAAAAACCAACTTTAGTTGCTTAATACTCAAAGCAAATATTCGAT
TATATGCGCTAAAGAGAGATTGCCTTCAAAGTCGGTGAATACATGGAAAAATAAACTTAA
ATCAATGACAGAATGAGAGCCATTTTGGTTGACTGGATTGTGGAAATACATAGAAAGTGT
AAATTGTTACCTGAAACTTTATTTATTACTGTCAATTTAATTGACCGCTTCTTGGATAGA
GCCACATGCACTAGAGATAATTTATAGCTTGTAGGTGTAACTGCTTTGTTCATAGCTTCT
AAATACGAAGAAATATATCCTCCTAATCTTAATGATTTTGTTGAAGCCACCTAGAAAGCT
TACAGAAAAAATGATGTTTTATAAATGGAAGGAAGCATTATTTGTGCCCTAAATTTCAAC
TTAACAGTTCCCACATCTCTCCGTTTCCTTGAAAGATACGGACGCGTTGATAAACTTGAT
AAAAAATCTTTTGACATGAGCTTATATATTCTTTAACTCTGCTTAGTCGAATATAAATTT
GTTAAATACTCAGAATCATTAAAAGCTTGCGCTGCTATCTATCTCACAAATAAGCTATTT
AAAAAGAATATTTGCTGGAGTGATGTCCTCACTGGTCACACTTAACATACCGAGCAATAA
ATTAGACCTTGTGCTCTCGAAATGTGCCTTTTACTTCAATCAGCATCAACTAACTAAACC
CAAGCCGTTCGCAGAAAATTCCTTAGTTCAGAGTATAGCGAAGTAGCAACCATACAAATT
GAAAAAATGAATCCTTCATAATAAAACACACAATAGCATTCATATTAAAATAATTAAAAT
TACCCTCCCAACATTCCTAAATACAACTACAGAGAATAATATTGA


>TTHERM_00196590(gene)
ATGGCTTGCCTACAAATGAGAAATGGTGAATAATCCATGTTTGGAGACTCAAACAAATTA
TAAAGCAATCAACTTCGTGCTTTCGGGCGTGAGATTCAAAATATCCCTGACAGTCGCTTT
GTAAAAATTTTTTTCATTTTTCAAATTAATTTCAAATATCCATCTCTCTTATTTTGATGC
TTTTAAGCTTTTTTTTAAGCTGCTTCAACTAAAAGAGTTTGATGAAAGCTAAAGGGAAAA
GAAGGATATTGTTTCAAATGAAGCCATAGCATAGCTATCTCTCTTTAAAATTTTCTAACA
ATTATTTAATTTATAATAGAATACAAGATCTTAATCAATAAAAGCAAACATGTAGCCTCA
CCACGCCTAAAAGCTTAGCATGGAATTAGATACAAATATAAATGAATAAGAGAACGGAAT
GAAAAGAAGTTCTCCTAGAAAATTTTCAATGCATGTGAAGCATTCCTCCGAAGTTCCATA
AAACCATTAAAAGAGAATGTCAAGCTAAATTGACACTGTAAGCAATAATGGAACAGAGCG
CTCATATTAAACCAATTAAACTGGCCTTTAAAATAAAAATATTGACATGAAAAATATAGA
ATTTGAATTGAATAGGATTTCTAAGGAAGACTCTGAAAAACCAACTTTAGTTGCTTAATA
CTCAAAGCAAATATTCGATTATATGCGCTAAAGAGAGGTAAAAAAATACTTTCAAGCTCA
TTTATTTTATAATGACTCAAAATACCAAAAATGTTTGCCAACTAAAAATCATTTCCTCAG
CAAAGCAATTCATTTTAATTTTGTTAAGCATTCATTTTAAAATAAACATTTTTGTTTTTA
ATTTCCATCAAAGAAGTTGCTATTAAAAATTAAAAGTGATATTTTTGCTTTACGCAATTT
GAAATGTAAATTGAAATATCAAATAAGCAAGCAAGCAAATAAATAAACAAAATCCTTTTA
AATTAATAGAAAAATTTAAAATTAAATTGTAATAAGTATTATCCTAACTAATATTTTCTT
GCAAAATAATTCAAATAGTTTTATTTTTCGAGAGCCAAGTATTTTTTAGTATAATTATTC
GACTACTAATCTCCTGATTTAATTAAATTTGCAAATTAAAAATTGATCACTTTAAAATTC
AATTATTCAAAAATTAAATATCTAATAGAGTTTGTATCTAAATGTTTTTTAATCGAATTT
AAATTATTAACGATTAAACAAACATCTTTTTTAAAAAAGCGGCATGCTTAATTTATATTT
TCTAATTGAGAAATTTCAAATAAAAGGAAAATTATAAAATATTTTAAAATCACTCAATTT
CTAAAATTTATTTTATTCGTAAAATAAACTAGATTGCCTTCAAAGTCGGTGAATACATGG
AAAAATAAACTTAAATCAATGACAGAATGAGAGCCATTTTGGTTGACTGGATTGTGGAAA
TACATAGAAAGTGTAAATTGTTACCTGAAACTTTATTTATTACTGTCAATTTAATTGACC
GCTTCTTGGATAGAGCCACATGCACTAGAGATAATTTATAGCTTGTAGGTGTAACTGCTT
TGTTCATAGCTTCTAAATACGAAGAAATATATCCTCCTAATCTTAATGATTTTGTTGAAG
CCACCTAGAAAGCTTACAGAAAAAATGATGTTTTATAAATGGAAGGAAGCATTATTTGTG
CCCTAAATTTCAACTTAACAGTTCCCACATCTCTCCGTTTCCTTGAAAGATACGGACGCG
TTGATAAACTTGATAAAAAATCTTTTGACATGAGCTTATATATTCTTTAACTCTGCTTAG
TCGAATATAAATTTGTTAAATACTCAGAATCATTAAAAGCTTGCGCTGCTATCTATCTCA
CAAATAAGCTATTTAAAAAGAATATTTGCTGGAGTGATGTCCTCACTGGTCACACTTAAC
ATACCGAGCAATAAATTAGACCTTGTGCTCTCGAAATGTGCCTTTTACTTCAATCAGCAT
CAACTAACTAAACCCAAGCCGTTCGCAGAAAATTCCTTAGTTCAGAGTATAGCGAAGTAG
CAACCATACAAATTGAAAAAATGAATCCTTCATAATAAAACACACAATAGCATTCATATT
AAAATAATTAAAATTACCCTCCCAACATTCCTAAATACAACTACAGAGAATAATATTGA


>TTHERM_00196590(protein)
MACLQMRNGEQSMFGDSNKLQSNQLRAFGREIQNIPDSRFNTRSQSIKANMQPHHAQKLS
MELDTNINEQENGMKRSSPRKFSMHVKHSSEVPQNHQKRMSSQIDTVSNNGTERSYQTNQ
TGLQNKNIDMKNIEFELNRISKEDSEKPTLVAQYSKQIFDYMRQREIAFKVGEYMEKQTQ
INDRMRAILVDWIVEIHRKCKLLPETLFITVNLIDRFLDRATCTRDNLQLVGVTALFIAS
KYEEIYPPNLNDFVEATQKAYRKNDVLQMEGSIICALNFNLTVPTSLRFLERYGRVDKLD
KKSFDMSLYILQLCLVEYKFVKYSESLKACAAIYLTNKLFKKNICWSDVLTGHTQHTEQQ
IRPCALEMCLLLQSASTNQTQAVRRKFLSSEYSEVATIQIEKMNPSQQNTQQHSYQNNQN
YPPNIPKYNYREQY