Identifiers and Description

Gene Model Identifier

TTHERM_00201690

Standard Name

RAB49 (RAB GTPase 49)

Aliases

PreTt13740 | 17.m00347

Description

RAB49 Ras family small GTPase; Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase-mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00025 ) ADP-ribosylation factor family
• ( PF00071 ) Ras family
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00073 ) hydrogenase accessory protein HypB
• ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_01991.1	1.000382677035467e-28
	Description: hypothetical protein (178 aa)
DictyBase	DDB_G0292406	8.999890565246037e-26
	Description: rab4 on chromosome: 6 position 1558648 to 1559514
Oxytricha	Contig5831.0.g6	9.996273942859018e-26
	Description: Ras family
WormBase	WBGene00019317	1.0004572433669413e-23
	Description: status:Confirmed UniProt:Q21137 protein_id:CCD72274.1
SGD	YFL005W	5.0000961330688895e-23
	Description: SEC4 Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00201690(coding)
ATGTCTGCTAAAAACGACAGTAAATAAAAAATTATAAAATGTGCTTCAGTGGGAGATTAA
TTTGTTGGAAAATCTGCTCTATTTGTTAGGTAATTTCATGGAAAGTTTCTTCGATAAAAA
ACCGCTGGAGTTGATTTTTAAATTTTCGTTCTGAAAAAAGGAAATGAAGAAATTAAATTT
TAGTTTTGGGATTTAGGTTATAGGAGTAGATAAGAAGGATTAAAAGTTTATCCTTAAACT
TCTATTTTAATTATGATTTATGATATTACAAACAGAATCTCTTTTACAAATATTTAAAAA
TATTATGGAGATTATGTTAGATAAGGAAATAAAAAATCAATAATTGCTCTTGTCGGAAAT
AAGAAGGATCTAAATGAATATAGAGAAGTTTCATTTTTGGAAGGTTAAGAGCTGGGTAAA
TAGTTAGGTGTATATTTTTTTGAAGTATCTGCTTTTACAGGTGAAAATGTTAAAGATTTG
TATGAGTTCTTAATAGATAAGTCTATTGATACAGTCTAATTTTGA

>TTHERM_00201690(gene)
ATGTCTGCTAAAAACGACAGTAAATAAAAAATTATAAAATGTGCTTCAGTGGGAGATTAA
TTTGTTGGAAAATCTGCTCTATTTGTTAGGTAATTTCATGGAAAGTTTCTTCGATAAAAA
ACCGCTGGAGTTGATTTTTAAATTTTCGTTCTGAAAAAAGTAAAATAAATATTTCGAATT
TATTTTTTTAATAGATTTTATACATTTTAGGGAAATGAAGAAATTAAATTTTAGTTTTGG
GATTTAGGTTATAGGAGTAGATAAGAAGGATTAAAAGTTTATCCTTAAACTTCTATTTTA
ATTATGATTTATGATATTACAAACAGAATCTCTTTTACAAATATTTAAAAATATTATGGA
GATTATGTTAGATAAGGAAATAAAAAATCAATAATTGCTCTTGTCGGAAATAAGAAGGAT
CTAAATGAATATAGAGAAGTTTCATTTTTGGAAGGTTAAGAGCTGGGTAAATAGTTAGGT
GTATATTTTTTTGAAGTATCTGCTTTTACAGGTGAAAATGTTAAAGATTTGTATGAGTTC
TTAATAGATAAGTCTATTGATACAGTCTAATTTTGA

>TTHERM_00201690(protein)
MSAKNDSKQKIIKCASVGDQFVGKSALFVRQFHGKFLRQKTAGVDFQIFVLKKGNEEIKF
QFWDLGYRSRQEGLKVYPQTSILIMIYDITNRISFTNIQKYYGDYVRQGNKKSIIALVGN
KKDLNEYREVSFLEGQELGKQLGVYFFEVSAFTGENVKDLYEFLIDKSIDTVQF