Identifiers and Description

Gene Model Identifier

TTHERM_00213600

Standard Name

RFC3 (Replication factor C subunit 3)

Aliases

PreTt13842 | 17.m00449

Description

RFC3 replication factor C subunit 5; Subunit of Replication factor C (RF-C)- which acts as a clamp loader of the proliferating cell nuclear antigen (PCNA)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• DNA replication factor C complex (IEA) | GO:0005663

Molecular Function

• ATP binding (IEA) | GO:0005524
• DNA clamp loader activity (IEA) | GO:0003689

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF00004 ) ATPase family associated with various cellular activities (AAA)
• ( PF00071 ) Ras family
• ( PF00255 ) Glutathione peroxidase
• ( PF01078 ) Magnesium chelatase, subunit ChlI
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF03215 ) Rad17 P-loop domain
• ( PF04851 ) Type III restriction enzyme, res subunit
• ( PF06144 ) DNA polymerase III, delta subunit
• ( PF07726 ) ATPase family associated with various cellular activities (AAA)
• ( PF07728 ) AAA domain (dynein-related subfamily)
• ( PF08542 ) Replication factor C C-terminal domain
• ( TIGR00678 ) DNA polymerase III, delta' subunit
• ( TIGR01618 ) phage nucleotide-binding protein
• ( TIGR02397 ) DNA polymerase III, subunit gamma
• ( TIGR02928 ) orc1/cdc6 family replication initiation protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_16737.1	9.997093137033517e-262
	Description: hypothetical protein (345 aa)
Oxytricha	Contig21432.0.g8	2.0000857274312427e-108
	Description: ATPase family associated with various cellular activities (AAA)
DictyBase	DDB_G0282235	3.999582750711782e-108
	Description: rfc5 on chromosome: 3 position 5553806 to 5555127
SGD	YNL290W	9.001030883757984e-98
	Description: RFC3 Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
WormBase	WBGene00018409	5.0014751778710277e-85
	Description: Probable replication factor C subunit 5 status:Partially_confirmed UniProt:P34429 protein_id:CCD63451.1
Stentor Coeruleus	SteCoe_23189	4.1863939993042314e-51
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00213600(coding)
ATGGAAGAGGAAATACCCATTACAGTTGAAACCAAATAGAAGTAATAGAATATTCCTTGG
GTTGAAAAATACAGACCTGAGAACTTAGATAATGTCATTTCACATGAGTATATTGTTGCA
ACAATTAAGAAATTTATTGAAGAAGATAAGAAGCTTCCTAATTTATTGTTTTATGGACCT
CCAGGAACAGGTAAGACCTCATTAATAGTAGCTTTAGCCAAATAGTTGTATGGAAAGAAT
TATAAATAGCTTGTTTTAGAACTTAACGCTTCTGATGATAGAGGTATTGACGTTGTTAGA
GAACAAATCAAAACTTTTGCAAGTACTGCCAATTTCGGTATGGTTGGAAAAGGAACTAAA
TTAATTATTTTGGATGAAGCAGACTCTATGACAAATCAAGCTCAGTTTGCTTTGAGAAGA
ATTATTGAAAAATACAGCAGCAATGCTAGATTTTGCATGATATGTAATTACGTCTCAAAA
ATTATTCCTGCTCTCCAATCAAGATGCACAAGATTTAAGTTCAAGCATATTCCTTATTAA
GATGCTAAACTTAGAATTGCATAAATTTGCAATGCTGAAAATTTAAAATATAAAAATTCT
GGTATTGAAGCAGTATTCAAGCTTTGCGATGGAGATATGAGAAGAGTTGTAAATATGCTT
CAATCTCTTTCTTTATAAGGATATGGAAGTGATGAATAAGTAGAAATAACTGATGAATTA
GTTTATAAATTTACAGGTAATGCAACACCAAAAGACATTGAAAATATTATTAACACCATG
AATAATAAATCCATTTCAGAATCATATGAAATAATATAGAGTTACTAGGTAGAAAAAGGT
ATCTCCTTATAAGTTATGTTGAAAGAAATAAGTCTTTTTTTGATGAATACCTCATATCCT
AGCTTAGCACTTGAATTTTTAGTTAAAAGATTGGCAGATCTTGAATATAGAATGTCAATT
AACTGTGATGAAAAAGTTTAAACATTATCATTAATAAGTGCCTTCACAGAAGTTCGTTAG
CTTTTAAGAAGACCTTGA

>TTHERM_00213600(gene)
ATGGAAGAGGAAATACCCATTACAGTTGTAAAATAAAGCTAAAGCATTTTTACAAAATTG
TAATTCGTTTGTTTTTTATTAGGAAACCAAATAGAAGTAATAGAATATTCCTTGGGTTGA
AAAATACAGACCTGAGAACTTAGATAATGTCATTTCACATGAGTATATTGTTGCAACAAG
TAAATAAAATTTGAAAGCTAATCAGAATAAATAAGCAAACAACTTTTTTATTACATTTTT
TAATAGTTAAGAAATTTATTGAAGAAGATAAGAAGCTTCCTAATTTATTGTTTTATGGAC
CTCCAGGAACAGGTGATTCATTCATATCAACTTTTTTTGTACAATATATATAAATTATTA
TTATATAAAACAGGTAAGACCTCATTAATAGTAGCTTTAGCCAAATAGTTGTATGGAAAG
AATTATAAATAGCTTGTTTTAGAAGTAATTTAGCTCAATTTATTTTAATTAGTGATAAGG
TTTTATTAAAAAAAGCTTAACGCTTCTGATGATAGAGGTATTGACGTTGTTAGAGAACAA
ATCAAAACTTTTGCAAGTACTGCCAATTTCGGTATGGTTGGGTAAATAAATATTAAAATT
TTATATAGATTTCATTGAAAAATAAATAGCAGAAAGGCATACATGTAGCCTTCAAGAAGT
ACTTGCAAGAATATTAAAATATTTTGAAATAAATTTAAAATTTGATAATAATAATAAAAA
TTAAAAGAAAAGGAACTAAATTAATTATTTTGGATGAAGCAGACTCTATGACAAATCAAG
CTCAGTTTGCTTTGAGAAGAAGTAAAATGAAATAAAAAACTAGTTTATAGGAAAAAATAA
TTATTTTCAATTAATTTATTAGTTATTGAAAAATACAGCAGCAATGCTAGATTTTGCATG
ATATGTAATTACGTCTCAAAAATTATTCCTGCTCTCCAATCAAGATGCACAAGATTTAAG
TTCAAGCATATTCCTTATTAAGATGCTAAACTTAGAATTGCATAAATTTGCAATGCTGAA
AATTTAAAATATAAAAATTCTGGTATTGAAGCAGTATTCAAGCTTTGCGATGGAGATATG
AGAAGAGTTGTAAATATGCTTCAAGTAAATAAAATATTAAAATATGTTAATGGAAATAAT
TTACTTATTTATTTTTTTAAAAACAAAAATAGTCTCTTTCTTTATAAGGATATGGAAGTG
ATGAATAAGTAGAAATAACTGATGAATTAGTTTATAAATTTACAGGTAATGCAACACCAA
AAGACATTGAAAATATTATTAACACCATGAATAATAAATCCATTTCAGAATCATATGAAA
GTAAATTAATTAATTAAATCTGCTTTAAAATAAATTTTATAAAAAATCGAATTATTTATT
AGTAATATAGAGTTACTAGGTAGAAAAAGGTATCTCCTTATAAGTTATGTTGAAAGAAAT
AAGTCTTTTTTTGATGAATACCTCATATCCTAGCTTAGCACTTGAATTTTTAGTTAAAAG
ATTGGCAGATCTTGAATATAGAATGTCAATTAACTGTGATGAAAAAGTTTAAACATTATC
ATTAATAAGTGCCTTCACAGAAGTTCGTTAGCTTTTAAGAAGACCTTGA

>TTHERM_00213600(protein)
MEEEIPITVETKQKQQNIPWVEKYRPENLDNVISHEYIVATIKKFIEEDKKLPNLLFYGP
PGTGKTSLIVALAKQLYGKNYKQLVLELNASDDRGIDVVREQIKTFASTANFGMVGKGTK
LIILDEADSMTNQAQFALRRIIEKYSSNARFCMICNYVSKIIPALQSRCTRFKFKHIPYQ
DAKLRIAQICNAENLKYKNSGIEAVFKLCDGDMRRVVNMLQSLSLQGYGSDEQVEITDEL
VYKFTGNATPKDIENIINTMNNKSISESYEIIQSYQVEKGISLQVMLKEISLFLMNTSYP
SLALEFLVKRLADLEYRMSINCDEKVQTLSLISAFTEVRQLLRRP