Identifiers and Description

Gene Model Identifier

TTHERM_00215960

Standard Name

AOS2 (Activation Of Smt3p 2 )

Aliases

PreTt22220 | 18.m00246 | 3701.m00009

Description

ThiF family protein; Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00899 ) ThiF family
• ( TIGR00055 ) di-trans,poly-cis-decaprenylcistransferase
• ( TIGR02354 ) thiamine biosynthesis protein ThiF
• ( TIGR02355 ) molybdopterin synthase sulfurylase MoeB
• ( TIGR02356 ) thiazole biosynthesis adenylyltransferase ThiF

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_06564.1	9.997093137033517e-262
	Description: ThiF family protein (520 aa)
DictyBase	DDB_G0287965	7.996627236682682e-106
	Description: nae1 on chromosome: 5 position 887341 to 889297
Oxytricha	Contig9991.0.g10	1.999022616705709e-90
	Description: ThiF family
WormBase	WBGene00006735	1.0004460510701209e-64
	Description: locus:ula-1 NEDD8-activating enzyme E1 regulatory subunit status:Confirmed UniProt:Q18217 protein_id:CCD65733.1
Stentor Coeruleus	SteCoe_30113	1.1089390193121365e-40
	Description: None
SGD	YPR180W	4.9988726541653934e-26
	Description: AOS1 Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00215960(coding)
ATGTCATCTAAAGATAAATACGATAGATAGCTTCGTCTTTGGGGTCCTCAAGGCTAAAGA
AAGTTGGCCAATTCTAAGATTTTGCTCTTAGGAGCAGCACCTGCAGGAGTTGAAGCTCTT
AAAAATTTAGTTTTACCAGGATGCGGTCACATTACTATTGTAGACCACCAACTCATTACT
GAGAGAGATTTAGGAAACAATTTTTTCTGCTCTCCTGAAGATTTAGGTCAACCCCGTGCT
AAGAGTGTCTGTGATAATCTTACAGAAATGAATCCTGAAGATGTTCATGGTAAGTGGCTT
AATGAAAATGTAGATGAATTAGCTGCTAAGGAAGATTTTATTAAAGAGTTTACTTGCGTT
ATAGCAAATGAGTTGCTTGATGAAGAACTTCATAAGCTATCTGTTATTTGTGATAAATAT
AATATTAAATTACTGGCAATCTAAACAAATGGATTTTATGCTTAGTTGCGTCTCTAAGCA
GGTCGTCATTGCATTATAGAAAGCAAACCAGACAGAGACTTCTATGACTGGACTCTTCGT
ATCCGCCAACCTTTCTAACATCTTCAAGATTTTTGTGATAAATTTGATTTGTAGGATTTA
TCAACTCATGAAGATAAGAATCCTCTAGCTCACGTACCTTTTGTAGTTATTTTAGTAAAG
GCTATGAATGCATGGAAGCAATCTCATAATGGTAATGCTCCTTCATCAATCCAAGAAAAG
AATGAATTTAAAAAAACCATCGAGACTCAAATGCACTGGCTTGAAGCTAAGGATCGTGAA
AATTTCGAAGAAGCTCTTGCCAAGATTTACTGGGCTCATAAAGATGCTACCTAAATTCCA
GATAATTTATAAGTTCTTTTTGATCATGATTATTGTAAAAATTTGGATCACTCTAGCTCT
GATGACTTAAAGTTCTGGACTCTTGTAGCTGCTCTTAAGAAATTCCGTGATGAAAATAAC
CACTTCCTGCCTGTTGATCGTCGTATCCCAGATATGAAATCTACTACTGAATGGTATATC
TAATTAAAGGAGGTTTATCAAACCTAACACAATGCCGACCGTGAAGCTTTTGTAAAAATT
CTAAATTAAATAAATACCAAAAATCTTGTTTTTGATCAAAATGAGGATATTTAAGTATTC
CTTGATAATATTAACTGCTTAGAATTTATCGATTTCCACTCTATTGATAACGAGTTAACC
AAGCCAATTGAAACAGAAAACTATGATAACCAAAACCACCTTTGGTTTGTTGGATAAAGA
GCTGTTAATTAATTCTATTAAAAGCATAGAAGATTCCCCAATCCTTCTGATTAAGCAGAG
TTGTCTTAAATAGCAGCTTAAATAAGAGAAACTAAATATCCTAATTATGTTGCTATTGAA
GAAGGTATTATCTAGGAATTCTGTAGATACGAAGATTCCCGTCTTCATAATATTGCTGCT
ATTATTGGTGGAGTTGCATCTCAAGAAGCTATTAAGCTTATAACTAACTAGTTTGTCCCT
TTAAATAACACTTACATTTTTAATGGTATTACTTGTGAAGGTGTCACTTTAGAATACTGA

>TTHERM_00215960(gene)
ATGTCATCTAAAGATAAATACGATAGATAGCTTCGTCTTTGGGGTCCTCAAGGCTAAAGA
AAGTTGGCCAATTCTAAGATTTTGCTCTTAGGAGCAGCACCTGCAGGAGTTGAAGCTCTT
AAAAATTTAGTTTTACCAGGATGCGGTCACATTACTATTGTAGACCACCAACTCATTACT
GAGAGAGATTTAGGAAACAATTTTTTCTGCTCTCCTGAAGATTTAGGTCAACCCCGTGCT
AAGAGTGTCTGTGATAATCTTACAGAAATGAATCCTGAAGATGTTCATGGTAAGTGGCTT
AATGAAAATGTAGATGAATTAGCTGCTAAGGAAGATTTTATTAAAGAGTTTACTTGCGTT
ATAGCAAATGAGTTGCTTGATGAAGAACTTCATAAGCTATCTGTTATTTGTGATAAATAT
AATATTAAATTACTGGCAATCTAAACAAATGGATTTTATGCTTAGTTGCGTCTCTAAGCA
GGTCGTCATTGCATTATAGAAAGCAAACCAGACAGAGACTTCTATGACTGGACTCTTCGT
ATCCGCCAACCTTTCTAACATCTTCAAGATTTTTGTGATAAATTTGATTTGTAGGATTTA
TCAACTCATGAAGATAAGAATCCTCTAGCTCACGTACCTTTTGTAGTTATTTTAGTAAAG
GCTATGAATGCATGGAAGCAATCTCATAATGGTAATGCTCCTTCATCAATCCAAGAAAAG
AATGAATTTAAAAAAACCATCGAGACTCAAATGCACTGGCTTGAAGCTAAGGATCGTGAA
AATTTCGAAGAAGCTCTTGCCAAGATTTACTGGGCTCATAAAGATGCTACCTAAATTCCA
GATAATTTATAAGTTCTTTTTGATCATGATTATTGTAAAAATTTGGATCACTCTAGCTCT
GATGACTTAAAGTTCTGGACTCTTGTAGCTGCTCTTAAGAAATTCCGTGATGAAAATAAC
CACTTCCTGCCTGTTGATCGTCGTATCCCAGATATGAAATCTACTACTGAATGGTATATC
TAATTAAAGGAGGTTTATCAAACCTAACACAATGCCGACCGTGAAGCTTTTGTAAAAATT
CTAAATTAAATAAATACCAAAAATCTTGTTTTTGATCAAAATGAGGATATTTAAGTATTC
CTTGATAATATTAACTGCTTAGAATTTATCGATTTCCACTCTATTGATAACGAGTTAACC
AAGCCAATTGAAACAGAAAACTATGATAACCAAAACCACCTTTGGTTTGTTGGATAAAGA
GCTGTTAATTAATTCTATTAAAAGCATAGAAGATTCCCCAATCCTTCTGATTAAGCAGAG
TTGTCTTAAATAGCAGCTTAAATAAGAGAAACTAAATATCCTAATTATGTTGCTATTGAA
GAAGGTATTATCTAGGAATTCTGTAGATACGAAGATTCCCGTCTTCATAATATTGCTGCT
ATTATTGGTGGAGTTGCATCTCAAGAAGCTATTAAGCTTATAACTAACTAGTTTGTCCCT
TTAAATAACACTTACATTTTTAATGGTATTACTTGTGAAGGTGTCACTTTAGAATACTGA

>TTHERM_00215960(protein)
MSSKDKYDRQLRLWGPQGQRKLANSKILLLGAAPAGVEALKNLVLPGCGHITIVDHQLIT
ERDLGNNFFCSPEDLGQPRAKSVCDNLTEMNPEDVHGKWLNENVDELAAKEDFIKEFTCV
IANELLDEELHKLSVICDKYNIKLLAIQTNGFYAQLRLQAGRHCIIESKPDRDFYDWTLR
IRQPFQHLQDFCDKFDLQDLSTHEDKNPLAHVPFVVILVKAMNAWKQSHNGNAPSSIQEK
NEFKKTIETQMHWLEAKDRENFEEALAKIYWAHKDATQIPDNLQVLFDHDYCKNLDHSSS
DDLKFWTLVAALKKFRDENNHFLPVDRRIPDMKSTTEWYIQLKEVYQTQHNADREAFVKI
LNQINTKNLVFDQNEDIQVFLDNINCLEFIDFHSIDNELTKPIETENYDNQNHLWFVGQR
AVNQFYQKHRRFPNPSDQAELSQIAAQIRETKYPNYVAIEEGIIQEFCRYEDSRLHNIAA
IIGGVASQEAIKLITNQFVPLNNTYIFNGITCEGVTLEY