Identifiers and Description

Gene Model Identifier

TTHERM_00218410

Standard Name

FRS2 (Phenylalanyl(F)-tRNA Synthetase 2)

Aliases

PreTt22268 | 18.m00294 | 3701.m00054

Description

FRS2 phenylalanyl-tRNA synthetase beta chain; Phenylalanyl-tRNA synthetase; beta subunit family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• magnesium ion binding (IEA) | GO:0000287
• phenylalanine-tRNA ligase activity (IEA) | GO:0004826
• RNA binding (IEA) | GO:0003723

Biological Process

• phenylalanyl-tRNA aminoacylation (IEA) | GO:0006432
• translation (IEA) | GO:0006412

Domains

• ( PF03483 ) B3/4 domain
• ( PF03484 ) tRNA synthetase B5 domain
• ( TIGR00471 ) phenylalanyl-tRNA synthetase, beta subunit
• ( TIGR00472 ) phenylalanyl-tRNA synthetase, beta subunit

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_06614.1	9.997093137033517e-262
	Description: phenylalanyl-tRNA synthetase, beta subunit protein (591 aa)
WormBase	WBGene00001498	6.002322951831963e-178
	Description: locus:fars-3 Phenylalanine--tRNA ligase beta subunit status:Confirmed UniProt:Q19713 protein_id:CAA90360.1
Tetrahymena borealis	EI9_12076.1	6.002322951831963e-178
	Description: hypothetical protein (206 aa)
DictyBase	DDB_G0277303	2.0002969069156684e-168
	Description: phesB on chromosome: 2 position 7623909 to 7626465
Oxytricha	Contig14504.0.g56	1.9994249217050915e-157
	Description: B3/4 domain
SGD	YLR060W	9.995193436412938e-154
	Description: FRS1 Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate active enzyme; able to hydrolyze mis-aminoacylated tRNA-Phe, which could contribute to translational quality control
Stentor Coeruleus	SteCoe_14429	6.714184288211594e-79
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00218410(coding)
ATGCCTATTGTCTCTGTTAACATTAAAAATTTCTTCAAAAAGTTAGGAAAGGAACTCAAA
TTCCACGAATTGGAAGAATTATGCTTCGAATATGGTATCGAAGTAGAAGAAAAGGAAGTC
TCCAAGAAAAATAAGAAGTCAGGCAAAGAAGAAAAAGTTAAAGAATATGCTTTTGAAGTT
GGTGCTAACAGACCTGATTTACTCTCTGTAGAAACTCTTACTTAAGCTTTGGGAGTCTTT
ATTGGTACTCGCCAACCCCCTCAATATACAGTAAAGCCTGTTGAACAAAGATAAAAGATT
ATTGTTAAGAAGGATTGCAAGCGTATTAGACCTTTTGTTGTTGGTGCTGTTTTGAGAAAT
GTTACCTTCACTCAAGAATCCTATGATTCTTTCATTGACTTCTAAGATAAGTTACATCAC
AATCTTTGTCGTAGAAGAAGATTAGTCGCTATTGGTACTCATGATTTAGATACCATATAA
GGTCCTTTTACTTATGATGCTAGAAACCCTGCTGACATCAAGTTTGTACCTCTCGATAAA
ACCGAAAGCATGGATGGAAACAGACTTATGGAATTTTACGAAAAAGACTCTCACTTAAAA
GATTTCTTACCCATTATCAGAAATTCTCCTGTTTATCCTGTAATTCTTGACTCAAATAAT
GTTGTATGCTCTCTTCCTCCCATCATTAATGGTGACCACTCTAAAATTAAACTTACTACT
AAAAACGTTTTTATTGAATCAACTGCTACTGACTATACTAGAGCTTTGATTGCCTTAAAC
TGTTTAGTTGCTGCCTTCTCTGAATATTGTGCTGAACCCTACACCGTCGAAGAAGTTGAA
ATTCATTATGAAGAAGAAAATAGAACAGATATTACTCCCTAATTTACTATTAATAAATTT
TAAACTAAAATTTCTCACTTAAACAGCGTTGGTACCATCAATGTTACTGCAGAATAAGCT
TGCAAATTATTAGAAAGAATGAGTCTTACTGCAAAAGTTCTTAATAATGATGAAATCGAA
GTAGCTGTCCCAATCACCAGAGGAGATATTCTTTAAGAGTGTGATATTATTGAAGACGTT
TGCATTGCATACGGTTTCAAAAACATCAAGGCTGTTTTACCTAAAACTCCTACTGTTGGT
AAATAATTATTACTCAACAAGATGAGTGATTTGATTCGTGAAGAAATCGCTGCAGCTGGT
TATAAGGAAGGTCTTAATTTCGTTTTAGTTTCAAGAGATGATTTAACCAAAAAGCTTAAA
AAGGAAAATGATGAATAAATGATTATTATTGACAACCCCAAAACTGAAGAATTCAGCGTT
GGTAGAACTACACTTCTTCCTGGTTGCCTTAAATGGTTATCATCAAATAAAAAGAATAAG
ATCCCTATCAGTATGTTTGAAGTTGGTGATGTTATTTTGAAGGATGAAACTAGAGAAACT
AATACCAGAAACGAAAGAAGATTATGTGCTATCTACACTAATCACAACTCTGAATTAGAA
GTTGTTCATGGTTTACTTGATTATATTATGTTAAAGCTTATGGTTAACCTTGATTCTACA
GGAACTTGTAAGGCAGAAAGAAGATACAGACTTGTTCCTTCTGATGAACCTACATATTTC
TTAGATAGATAAGCTCATGTCTACTACAATGATAAGAAAATCGGAAATTTGGGTATCTTA
CATCCAGATGTTGTTAAAAATTTCGAATGGAAATATCCCGTTTCTGTTTTGGAATTAAAT
TTAGAACCTCTTATTAACGAATTCCACTAATGA

>TTHERM_00218410(gene)
ATGCCTATTGTCTCTGTTAACATTAAAAATTTCTTCAAAAAGTTAGGAAAGGAACTCAGT
AAAAATATTCATTACATTCTCATATAGAATAAACAATAAAATAATTATTTTATTCAAATC
TAAATTAAAATAAATTAATATGATCAGAAACATTCAAATATTTGATAATATGGATCATAA
ATGAAACAACATATTCAACAAGCTTCAATTTAACTTCTTTTCTCAAATAATAACAATTTG
AATACTAAAATCTTATCACTTTATTTAATTATGAACAGAATTCCACGAATTGGAAGAATT
ATGCTTCGAATATGGTATCGAAGTAGAAGAAAAGGAAGTCTCCAAGAAAAATAAGAAGTC
AGGCAAAGAAGAAAAAGTTAAAGAATATGCTTTTGAAGTTGGTGCTAACAGACCTGATTT
ACTCTCTGTAGAAACTCTTACTTAAGCTTTGGGAGTCTTTATTGGTACTCGCCAACCCCC
TCAATATACAGTAAAGCCTGTTGAACAAAGATAAAAGATTATTGTTAAGAAGGATGTAAT
ACATTAATTTAAAAAAAATAAATAGGAAACATTTAAATAATCCAAATAGTTTTATTCAGA
AAGCAAAAAATAAAAAAAAAGTTGATAGAAATGATATTAATTTTTTGATTTTATTCATCA
GTTAAATTGTTTTTTATTCTACCAAGCATTTGCTTTTCTGAGCTCTCTATATTTTAGCAT
TATTCTAAATTTTTATAATTTGAAAAAAGTGCAAGCGTATTAGACCTTTTGTTGTTGGTG
CTGTTTTGAGAAATGTTACCTTCACTCAAGAATCCTATGATTCTTTCATTGACTTCTAAG
ATAAGTTACATCACAATCTTTGTCGTAGAAGAAGATTAGTCGCTATTGGTACTCATGATT
TAGATACCATATAAGGTCCTTTTACTTATGATGCTAGAAACCCTGCTGACATCAAGTTTG
TACCTCTCGATAAAACCGAAAGCATGGATGGAAACAGACTTATGGAATTTTACGAAGTAA
ATTTTAAATATGTTTTAAATGAAATTTATATAATAATTTATTAATATTTGTAGAAAGACT
CTCACTTAAAAGATTTCTTACCCATTATCAGAAATTCTCCTGTTTATCCTGTAATTCTTG
ACTCAAATAATGTTGTATGCTCTCTTCCTCCCATCATTAATGGTGACCACTCTAAAATTA
AACTTACTACTAAAAACGTTTTTATTGAATCAACTGCTGTAATAAATATTTAAAAATTTT
ATTTAATTAAATTAAAATATTATTTATATTTTAAAGACTGACTATACTAGAGCTTTGATT
GCCTTAAACTGTTTAGTTGCTGCCTTCTCTGAATATTGTGCTGAACCCTACACCGTCGAA
GAAGTTGAAATTCATTATGAAGAAGAAAATAGAACAGATATTACTCCCTAATTTACTATT
AATAAATTTTAAACTAAAATTTCTCACTTAAACAGCGTTGGTACCATCAATGTTACTGCA
GAATAAGCTTGCAAATTATTAGAAAGAATGAGTCTTACTGCAAAAGTTCTTAATAATGAT
GAAATCGAAGTAGCTGTCCCAATCACCAGAGGAGGTAATAATTACAAAAAGACAAAATAT
GAAATAAACTATATTTTTAAAATTAATGTAACAGATATTCTTTAAGAGTGTGATATTATT
GAAGACGTTTGCATTGCATACGGTTTCAAAAACATCAAGGCTGTTTTACCTAAAACTCCT
ACTGTTGGTAAATAATTATTACTCAACAAGATGAGTGATTTGATTCGTGAAGAAATCGCT
GCAGCTGGTTATAAGGAAGGTCTTAATTTCGTTTTAGTTTCAAGAGATGATTTAACCAAA
AAGCTTAAAAAGGAAAATGATGAATAAATGATTATTATTGACAACCCCAAAACTGAAGAA
TTCAGCGTTGGTAGAACTACACTTCTTCCTGGTTGCCTTAAATGGTTATCATCAAATAAA
AAGAATAAGGTAATTTACTATAATTGACTACAAATAGCATAACATTTGAATTTAAAATAG
ATCCCTATCAGTATGTTTGAAGTTGGTGATGTTATTTTGAAGGATGAAACTAGAGAAACT
AATACCAGAAACGAAAGAAGATTATGTGCTATCTACACTAATCACAACTCTGAATTAGAA
GTTGTTCATGGTTTACTTGATTATATTATGTTAAAGCTTATGGTTAACCTTGATTCTACA
GGAACTTGTAAGGCAGAAAGAAGATACAGACTTGTTCCTTCTGATGGTAAGATTATTTAA
AAATAGATATTATTTAATTAACCATTTATTATTTTAGAACCTACATATTTCTTAGATAGA
TAAGCTCATGTCTACTACAATGATAAGAAAATCGGAGTAAAATTTATAATTTTCTAAAAA
TATAAATGTTAAAAAATATTTGTTTTAAAAAAAGAATTTGGGTATCTTACATCCAGATGT
TGTTAAAAATTTCGAATGGAAATATCCCGTTTCTGTTTTGGAATTAAATTTAGAACCTCT
TATTAACGAATTCCACTAATGA

>TTHERM_00218410(protein)
MPIVSVNIKNFFKKLGKELKFHELEELCFEYGIEVEEKEVSKKNKKSGKEEKVKEYAFEV
GANRPDLLSVETLTQALGVFIGTRQPPQYTVKPVEQRQKIIVKKDCKRIRPFVVGAVLRN
VTFTQESYDSFIDFQDKLHHNLCRRRRLVAIGTHDLDTIQGPFTYDARNPADIKFVPLDK
TESMDGNRLMEFYEKDSHLKDFLPIIRNSPVYPVILDSNNVVCSLPPIINGDHSKIKLTT
KNVFIESTATDYTRALIALNCLVAAFSEYCAEPYTVEEVEIHYEEENRTDITPQFTINKF
QTKISHLNSVGTINVTAEQACKLLERMSLTAKVLNNDEIEVAVPITRGDILQECDIIEDV
CIAYGFKNIKAVLPKTPTVGKQLLLNKMSDLIREEIAAAGYKEGLNFVLVSRDDLTKKLK
KENDEQMIIIDNPKTEEFSVGRTTLLPGCLKWLSSNKKNKIPISMFEVGDVILKDETRET
NTRNERRLCAIYTNHNSELEVVHGLLDYIMLKLMVNLDSTGTCKAERRYRLVPSDEPTYF
LDRQAHVYYNDKKIGNLGILHPDVVKNFEWKYPVSVLELNLEPLINEFHQ