Identifiers and Description

Gene Model Identifier

TTHERM_00219420

Standard Name

CAC2 (CAF1 subunit Cac2)

Aliases

PreTt22370 | 18.m00396 | 3701.m00155

Description

CAC2 Chromatin assembly factor 1 subunit Cac2 (FAS2); Homolog of human Chaf1b; Cac2 contains WD40 repeats and a highly conserved Asf1-interacting B-domain-like motif; Localizes predominantly to MIC and also to MAC during vegetative growth, similar to Asf1 localization (Nabeel-Shah et al., 2023); Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF00400 ) WD domain, G-beta repeat

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:37024975: Nabeel-Shah S, Garg J, Ashraf K, Jeyapala R, Lee H, Petrova A, Burns JD, Pu S, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2023) Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation. Epigenetics & chromatin 16:10
  2. Ref:34086947: Nabeel-Shah S, Garg J, Saettone A, Ashraf K, Lee H, Wahab S, Ahmed N, Fine J, Derynck J, Pu S, Ponce M, Marcon E, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2021) Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. Nucleic acids research ( ):

Sequences 

>TTHERM_00219420(coding)
ATGAAGTTAGAAAGACCTTTTATAGTATGGCATGGACAATATCAAAGAATTGTCACCTTA
GATGTTCATCCTTTTATAAATTTATTAGTAACAGGAGGTTCCGATGAAGAAGTTTATGAA
GGAGAAGATTTAGAATTTGAAGAAGAAATAGGTTATATCAAGTTGTGGTAGATTAACGAA
AACTACACACCAGGCTAAGGTGGAGATGCAAAACCAGTAACTTTTATAAGAGCTTTAAAA
AAACATTCAAATCCTGTAAATTGTGTTAGATTTTCACCTAATGGTTAGTATTTGGCATCA
GCTTCAGATGATCATAAAATTGTCATTTGGCATGTTGATAAGGGGTTTTAGAATATAAGC
ACTAATTAGAAAATATTCAATTTAGTTCCTAAAAATATATTAGAAGGACACAATCGCGAA
GTTTGTGATCTTAGATGGTTTAATGATAGTACTCATTTAATTTCAGGTGGAATGGATTAT
AGAGCATATATATGGAATGTTAAAGAAGGCGTGATTAAGCAAACTATAGTTGGAGCACAT
AAAAGTTATGTATAAGGAGTAGCTGTAGACCCAAAAATGAAATTTTGTCTTACTTTGGGT
AATGATAGAACTGTCAAAGTATGGAGAAAGCTAAAAAGCAATAATAAAAAGAAAAATATT
TTTGAATACATTCCATCAAATACAATGAAGAGATTACCTTTTGCAGATGTTAATATTGAA
GAAGAAATGCTTTCTGATGATGAAGATAAATCAAGTATTACAGGAAATTAAATGAATGGA
GCTAATGGAGCTGTTAATTAAGCTATGACTTATGGTATGTTTTTGTCAGAAAGATAACTT
AATACATTTGTAAAAAGACCTGATTGGAGTCCAGACGGTTCCTTCTTCTTACTTCCTGCT
GCTATTTATTAAGAGAAGAGAGACTCGAAAATAGAAATGTGCGTTTATTTATATCGTAGA
AATGTGTTAAATAAGCCATCACTCATAATAAATACAAATAATAAACCTGCTATTTGCACT
AGATTCTGTTAAAAATTATTTAAAAAGAAAGAGGAAAATTAATTTAGTATGGTTGATATA
CCATACGTAATAATTTTTGCTATTAGCACAATTGATAATGTTATGATATATTCCACAGCT
TCTCTTTCTCCTCTTGCTGTTGTAGGAAATATTCACTTTGCTCTTATTAATGATTTAACC
TTCTTCTCTAATTAATCTTTAATTATTTGTTCTTCTGACGGTATGTGCTCTTTTGTATTT
TTTGAAGAAAATGACCTTGGAAAACCATTAAATTCAGAAGAAATTTAAGATGAAGAAATT
AGAAATATTGTAAATGTTGAAAGCTTTTATCCAAATGAGCTTCTCAGAGCATTAGTGTAT
CCCAGTTAAACAAAGCAAATACTAAAAGAATACAATGAAAATATTAAATAATAATAAAAA
TAACAATAGTAAATAACAGATATAAATAGTTAAAAAGAAGAAAAAAATAAAGAATATGTT
GTAGAAAAATTTAATTTTGCTTGCATGGAGGAAGAGGAGTAAATTATTCCAATAAAACCT
CAAGAAATATAGTTTAAAACAACTTCTACAGGAGAGAAGAAAAAAGTAATTATTCCTGCA
GTTATTAAGAAATACTGA



>TTHERM_00219420(gene)
ATTTTAATTATAAATATATCTAGTTTGCTCTTTATTTAAAGATAAGTGTTATTTCAAAAT
TATTAGCAATAGAAATGAAGTTAGAAAGACCTTTTATAGTATGGCATGGACAATATCAAA
GAATTGTCACCTTAGATGTTCATCCTTTTATAAATTTATTAGTAACAGGAGGTTCCGATG
AAGAAGTTTATGAAGGAGAAGATTTAGAATTTGAAGAAGAAATAGGTTATATCAAGTTGT
GGTAGATTAACGAAAACTACACACCAGGCTAAGGTGGAGATGCAAAACCAGTAACTTTTA
TAAGAGCTTTAAAAAAACATTCAAATCCTGTAAATTGTGTTAGATTTTCACCTAATGGTT
AGTATTTGGCATCAGCTTCAGATGATCATAAAATTGTCATTTGGCATGTTGATAAGGGGT
TTTAGAATATAAGCACTAATTAGAAAATATTCAATTTAGTTCCTAAAAATATATTAGAAG
GACACAATCGCGAAGTTTGTGATCTTAGATGGTTTAATGATAGTACTCATTTAATTTCAG
GTGGAATGGATTATAGAGCATATATATGGAATGTTAAAGAAGGCGTGATTAAGCAAACTA
TAGTTGGAGCACATAAAAGTTATGTATAAGGAGTAGCTGTAGACCCAAAAATGAAATTTT
GTCTTACTTTGGGTAATGATAGAACTGTCAAAGTATGGAGAAAGCTAAAAAGCAATAATA
AAAAGAAAAATATTTTTGAATACATTCCATCAAATACAATGAAGAGATTACCTTTTGCAG
ATGTTAATATTGAAGAAGAAATGCTTTCTGATGATGAAGATAAATCAAGTATTACAGGAA
ATTAAATGAATGGAGCTAATGGAGCTGTTAATTAAGCTATGACTTATGGTATGTTTTTGT
CAGAAAGATAACTTAATACATTTGTAAAAAGACCTGATTGGAGTCCAGACGGTTCCTTCT
TCTTACTTCCTGCTGCTATTTATTAAGAGAAGAGAGACTCGAAAATAGAAATGTGCGTTT
ATTTATATCGTAGAAATGTGTTAAATAAGCCATCACTCATAATAAATACAAATAATAAAC
CTGCTATTTGCACTAGATTCTGTTAAAAATTATTTAAAAAGAAAGAGGAAAATTAATTTA
GTATGGTTGATATACCATACGTAATAATTTTTGCTATTAGCACAATTGATAATGTTATGA
TATATTCCACAGCTTCTCTTTCTCCTCTTGCTGTTGTAGGAAATATTCACTTTGCTCTTA
TTAATGATTTAACCTTCTTCTCTAATTAATCTTTAATTATTTGTTCTTCTGACGGTATGT
GCTCTTTTGTATTTTTTGAAGAAAATGACCTTGGAAAACCATTAAATTCAGAAGAAATTT
AAGATGAAGAAATTAGAAATATTGTAAATGTTGAAAGCTTTTATCCAAATGAGCTTCTCA
GAGCATTAGTGTATCCCAGTTAAACAAAGCAAATACTAAAAGAATACAATGAAAATATTA
AATAATAATAAAAATAACAATAGTAAATAACAGATATAAATAGTTAAAAAGAAGAAAAAA
ATAAAGAATATGTTGTAGAAAAATTTAATTTTGCTTGCATGGAGGAAGAGGAGTAAATTA
TTCCAATAAAACCTCAAGAAATATAGTTTAAAACAACTTCTACAGGAGAGAAGAAAAAAG
TAATTATTCCTGCAGTTATTAAGAAATACTGAAAATAGTATATATTTAAAAACCATCCAT
AATAGTTAAATCAATATTAAAATAATTTTAGAATTATTATAGAAAGTTTAATTTTGTAAA
AGTAGATAAATAATTTATTAAAGATATATATAGTAAAAGCCCCTACAATAAAAT



>TTHERM_00219420(protein)
MKLERPFIVWHGQYQRIVTLDVHPFINLLVTGGSDEEVYEGEDLEFEEEIGYIKLWQINE
NYTPGQGGDAKPVTFIRALKKHSNPVNCVRFSPNGQYLASASDDHKIVIWHVDKGFQNIS
TNQKIFNLVPKNILEGHNREVCDLRWFNDSTHLISGGMDYRAYIWNVKEGVIKQTIVGAH
KSYVQGVAVDPKMKFCLTLGNDRTVKVWRKLKSNNKKKNIFEYIPSNTMKRLPFADVNIE
EEMLSDDEDKSSITGNQMNGANGAVNQAMTYGMFLSERQLNTFVKRPDWSPDGSFFLLPA
AIYQEKRDSKIEMCVYLYRRNVLNKPSLIINTNNKPAICTRFCQKLFKKKEENQFSMVDI
PYVIIFAISTIDNVMIYSTASLSPLAVVGNIHFALINDLTFFSNQSLIICSSDGMCSFVF
FEENDLGKPLNSEEIQDEEIRNIVNVESFYPNELLRALVYPSQTKQILKEYNENIKQQQK
QQQQITDINSQKEEKNKEYVVEKFNFACMEEEEQIIPIKPQEIQFKTTSTGEKKKVIIPA
VIKKY