Identifiers and Description

Gene Model Identifier

TTHERM_00245150

Standard Name

RFC2 (Replication factor C sububit 2)

Aliases

PreTt02411 | 21.m00242

Description

RFC2 replication factor C subunit; Subunit of Replication factor C (RF-C)- which acts as a clamp loader of the proliferating cell nuclear antigen (PCNA)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• DNA replication factor C complex (IEA) | GO:0005663

Molecular Function

• ATP binding (IEA) | GO:0005524
• DNA clamp loader activity (IEA) | GO:0003689

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF00004 ) ATPase, AAA family
• ( PF00270 ) DEAD/DEAH box helicase
• ( PF00931 ) NB-ARC domain
• ( PF04851 ) type III restriction enzyme, res
• ( PF06068 ) TIP49 C-terminus
• ( PF06144 ) DNA polymerase III, delta subunit
• ( PF07726 ) ATPase family associated with various
• ( PF07728 ) ATPase family associated with various
• ( PF08542 ) Replication factor C
• ( TIGR00678 ) DNA polymerase III, delta' subunit
• ( TIGR02237 ) DNA repair and recombination protein
• ( TIGR02397 ) DNA polymerase III, subunit gamma
• ( TIGR02902 ) ATP-dependent protease LonB
• ( TIGR02928 ) orc1/cdc6 family replication initiation protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_00630.1	9.997093137033517e-262
	Description: ATPase, AAA family protein (371 aa)
Oxytricha	Contig22064.0.g10	3.998986577109865e-118
	Description: ATPase family associated with various cellular activities (AAA)
DictyBase	DDB_G0286027	2.999467474389571e-105
	Description: rfc4 on chromosome: 4 position 3966261 to 3967572
SGD	YJR068W	2.999180586171967e-98
	Description: RFC2 Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
WormBase	WBGene00004340	9.995417076252815e-72
	Description: locus:rfc-4 Replication factor C subunit 4 status:Confirmed UniProt:P53016 protein_id:CCD63405.1
Stentor Coeruleus	SteCoe_4894	4.1863939993042314e-51
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00245150(coding)
ATGTAGGGCAAATTACTATTTAAAGGTTAGGCCGCTCCTAAGGGTGCTGCTGCAGGAGCA
AATACAAAGGATAACAATAGAATGGAAGAAGAAACTAAAACAGAAGAACTTAATAATAAT
TTGCTTCCTTGGGTTGAAAAATATCGTCCTAATAAAATTGAAGAAGTCAGCTACTAAGAG
GAAGTAATAAAGTCTCTCTAAGGTGTTTTATTATCAGGAAATCTACCTCACTTGATTCTA
CATGGACCTCCTGGTACTGGTAAAACTTCAAGTATCCTTGCCTTTGCAAAGCAACTTTAC
GGACCAACTTTTTACAAAGAGAGAATCTTAGAATTAAATGCATCTGATGATAGAGGTATT
CAAATAGTCAGAGATAAAATAAAAAAATTTGCACAATAAGTTGTCTCTAAGAATCCAGAT
AAATCATTTAAATGCCCAAATTTCAAAATTATTATTTTGGACGAAGCAGACTCAATGACT
ACAGAAGCTCAGTCAGCTTTAAGAAGAATCATTGAAGACACCTCTTCAACCACTCGTTTT
TGTATTATCTGTAACTACATTACTAAGATTATAGAACCATTAGGTAGTAGATGTGTCAAA
TTCAGATTTAAACCTATTCCACTTGAAGCTTAAATAACTAAACTAGAAGAAATATGTAAA
ACAGAAGATATTGAATATGAAAAGGAAGCTCTTGAAAAATTAATTAAAATATCAAACGGT
GATTTGAGAAAAAGTGTAAATCTTCTATAATCTGCATCTACTTTGTATGAAAAGGATATT
AAAGTTGAAGTTATTGAAGAAATTTCAGGAAGTATTCCTGACAATTAAGTATAGAAATTA
TATAAACTTCTTATTGGCAAGGATTTTGATAAATTAAAAGAAGGAGTTAAATAGTTCTTA
TACTAAGGGTATTCTCCTGATTAATTACTTTACTAATTCTCAGAGTATATCATTAGTTCT
AAAGATTTCAATGAAGTTAAAAAAGCTAGAATCCTTGAAAAAATTGCATTAGCTGATAAA
GGTTTAAACGAAAGAGCAGACTCTGAGTTGCAAATATTAAACATGTTCTCAAGCTGTCTT
TCTGTTTTACAAAATCCTGATACTGATTTAAAGAAAAAGTGA

>TTHERM_00245150(gene)
ATGTAGGGCAAATTACTATTTAAAGGTTAGGCCGCTCCTAAGGGTGCTGCTGCAGGAGCA
AATACAAAGGATAACAATAGAATGGAAGAAGAAACTAAAACAGAAGAACTTAATAATAAT
TTGCTTCCTTGGGTTGAAAAATAGTAATTAATCAATTATTTTAATTTAGCTTATTTATAA
ATCAAAGATGATTTAACTTAATAAAATAGTCGTCCTAATAAAATTGAAGAAGTCAGCTAC
TAAGAGGAAGTAATAAAGTCTCTCTAAGGTGTTTTATTATCAGGAAATGTAATTTCATAT
TAGTAGCCAGTTTAGTTATTAGAATAAAATTATTTTTTGCTCAAATAAAAAGCTACCTCA
CTTGATTCTACATGGACCTCCTGGTACTGGTAAAACTTCAAGTATCCTTGCCTTTGCAAA
GCAACTTTACGGGTAAATAAATAAATAATCAACATAAAGATGTTAAAAATATTTGCAATC
CAAACACATAGGCTTATAAATAAATATGATTTTATTTTTAATCAATAGACCAACTTTTTA
CAAAGAGAGAATCTTAGAATTAAATGCATCTGATGATAGAGGTATTCAAATAGTCAGAGA
TAAAATAAAAAAATTTGCACAATAAGTTGTCTCTAAGAATCCAGATAAGTAAAATAAAAC
TGATAGCATTAGGTGTAGATTAAATATTTATAATATTTTGGATAAAATAGATCATTTAAA
TGCCCAAATTTCAAAATTATTATTTTGGACGAAGCAGACTCAATGACTACAGAAGCTCAG
TCAGCTTTAAGAAGAATCATTGAAGACACCTCTTCAACCACTCGTTTTTGTATTATCTGT
AACTACATTACTAAGTAAAATAAATTTATTTCAGTTTTTACTAAGCTATTATAAAGATAT
AAAAATTAACTACAGGTTAGCCATATTATTTTACTAATTTGTTATAAAGATATAAAAATT
TACTGCAGAATAGCCATATTATTAAATAGAATATTAAATATTTCAATAAAAATTAATGTA
AATAGGCTAAATATTATTAGGCAATTTAAAATTTTAATCTAAAAATAAGAATTTAAAATA
GAATAAATTATATTAATTAAAAATGAAAAAACTTGTATAAAATAACAATATTTTAAATAA
AAATAACATAATACAATTATGCAGCTATATTTAATATTTTTAACATATTAAATTTTTAAT
AATAAAAGGATTATAGAACCATTAGGTAGTAGATGTGTCAAATTCAGATTTAAACCTATT
CCACTTGAAGCTTAAATAACTAAACTAGAAGAAATATGTAAAACAGAAGATATTGAATAT
GAAAAGGAAGCTCTTGAAAAATTAATTAAAATATCAAACGGTGATTTGAGAAAAAGTGTA
AATCTTCTATAATCTGCATCTACTTTGTATGAAAAGGATATTAAAGTTGAAGTTATTGAA
GAAATTTCAGGAGTAAATTATTTACTTTGTATAAACGTATTAAATTATTTTTAAATAAAA
ATAAAGAGTATTCCTGACAATTAAGTATAGAAATTATATAAACTTCTTATTGGCAAGGAT
TTTGATAAATTAAAAGAAGGAGTTAAATAGTTCTTATACTAAGGGTATTCTCCTGATTAA
TTACTTTACTAATTCTCAGAGTATATCATTAGTTCTAAAGATTTCAATGAAGTTAAAAAA
GCTAGAATCCTTGAAAAAATTGCATTAGCTGATAAAGGTTTAAACGAAAGAGCAGACTCT
GAGTTGCAAATATTAAACATGTTCTCAAGCTGTCTTTCTGTTTTACAAAATCCTGATACT
GATTTAAAGAAAAAGTGA

>TTHERM_00245150(protein)
MQGKLLFKGQAAPKGAAAGANTKDNNRMEEETKTEELNNNLLPWVEKYRPNKIEEVSYQE
EVIKSLQGVLLSGNLPHLILHGPPGTGKTSSILAFAKQLYGPTFYKERILELNASDDRGI
QIVRDKIKKFAQQVVSKNPDKSFKCPNFKIIILDEADSMTTEAQSALRRIIEDTSSTTRF
CIICNYITKIIEPLGSRCVKFRFKPIPLEAQITKLEEICKTEDIEYEKEALEKLIKISNG
DLRKSVNLLQSASTLYEKDIKVEVIEEISGSIPDNQVQKLYKLLIGKDFDKLKEGVKQFL
YQGYSPDQLLYQFSEYIISSKDFNEVKKARILEKIALADKGLNERADSELQILNMFSSCL
SVLQNPDTDLKKK