Identifiers and Description

Gene Model Identifier

TTHERM_00245740

Standard Name

NRK2 (NIMA-Related Kinase )

Aliases

PreTt02469 | 21.m00300

Description

NRK2 plant dual-specificity MAP kinase kinase family domain protein; NIMA (Never In Mitosis) related kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) Protein kinase domain
• ( PF01163 ) RIO1 family
• ( PF04394 ) Protein of unknown function, DUF536
• ( PF07714 ) Protein tyrosine and serine/threonine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_00513.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (544 aa)
WormBase	WBGene00013762	9.997093137033517e-262
	Description: status:Partially_confirmed UniProt:Q9NAL5 protein_id:CAB76739.2
Oxytricha	Contig16193.0.g77	6.000667945664035e-116
	Description: Protein kinase domain
DictyBase	DDB_G0270814	6.997794455893953e-54
	Description: nek2 on chromosome: 1 position 4847143 to 4848761
Stentor Coeruleus	SteCoe_34801	1.0377033238158346e-53
	Description: None
WormBase	WBGene00008956	1.9998745702418095e-48
	Description: locus:nekl-3 status:Confirmed UniProt:G5EFM9 protein_id:CAA92169.2
WormBase	WBGene00022358	1.9998745702418095e-48
	Description: status:Partially_confirmed UniProt:Q9BKW4 protein_id:CCD71466.2
SGD	YAR018C	4.9986056260133516e-43
	Description: KIN3 Nonessential serine/threonine protein kinase; possible role in DNA damage response

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00245740(coding)
ATGTCCTTGAAAGATTTTGTGAATTTATAGAAGATAGGTGAGGGCTCTTACTCAAGTGTC
CATAAAGTAAGAAGGATCTCAGATAACTAAGAATACGCCCTCAAAAAGGTTAAATTATCT
GGTTTAAGCGAAAAAGAGAAAGATAACGCTCTTAATGAGATAAGAATATTAGCAAGTATA
GCTCATCCAAACATGATTGCATATAAGGATGCCTTTTTTGATGAATCTTCTCACTCACTT
TGCATTGTTATGGAGTTAGCCGTCAACGGTGATCTTTCTAAAAAAATTGATAGTGCAAAA
AAAAGAAATAGCTTTGTTCCAGAAGAAGAAATTTGGACAGTAGCGTTGCATATGTTAAGA
GGTTTGAAAGCTATGCACTCCAAAAAGATTCTTCACAGAGACCTCAAGTGTGCAAATGTC
TTTATTTCCAAGCAAGATGAATACAAAATTGGTGATCTCAATGTCTCAAAAGTCGCCAAA
AGAGGACTAGTATACACTTAAACTGGTACTCCTTATTACGCATCACCTGAAGTTTGGAGA
GATGAACCATATGACAGTTCAAGCGATATTTGGTCATTTGGATGCATTTTATACGAATTA
GCAGCTCTTAATCCACCATTTAGAGCTAAAGATATGGAAGGATTGTATAAAAAAGTATAG
AAAGGTATATTTGAGAGAATTCCATAAAGATATTCTAATGATTTGTAGAAGTTTATTGCA
TTATGCCTTTAGGTTAGTAGTGTATAACGTCCTTCTGTTACTTAGCTTTTAAACAATGTA
CTTCTTAAGCGTAATACCTAATTTTTAGCAGAATCTCCTGAAGAGTAATAAGATAAGGAA
AACACCCTTAGCCCAGAAGACCTTTTAAACACAATCAAAATGCCTAAAAACCCTCGTTAG
CTTAAGGAAAAGCTCCCAAAGCCTTAATATGATAAAGAGATATTAAATAATTCATATGAT
GGAGAAATACAACGCAAGGAGCGTAACCACAATAGGAATATGTCTGTAAAAATGAATAGG
ATATAATCTGTAACCAACCATAAATAGCATTAATACCTATAATAGTAATAGCAACTAATG
TTGGAGTAGGAAGGAAAAGATGTTGTTTTACCTTTAATTCCCAGATCATAATAATAAAAA
ATATTAGAACCTATAAGTAACAGCTAGTTACAGGCATAACAAAATAATAGCAATATTATA
GGTAGCTAAAATGATATTTATTCTAGAATAGGTAGCAACAGATATGAAAATTCTTCATCC
ATAGTTAGTGATTCCAGAAATTACTTGCAGGAAATACAGCCAAAAAAGCGAATTAATTAA
AATGGTTCAAGTGGTAACTACAATGAAGATTACTCCTAAAAATATAATAGATATGATTAA
CAACCAAGGTCAATAAACTCTCCAACTATATCTGTAATTTCTAAAAAGGATACAGGGTAT
TCAAATCCAGTGAACTCCATTAATCCACTAAGAAACAGAGTTAATTCTATAAATCAAATC
AATAGTTATGCAAGAATAGCTAATTTATATTAAAATTCTAAAAATCCCTATAACAACTAC
AGCGGAAATTCGATGCAGAGTGTTTCAATCGACTACAATCCTTAATATTCTCGTCCTGTT
TGGTGGGGTTGA

>TTHERM_00245740(gene)
ATGTCCTTGAAAGATTTTGTGAATTTATAGAAGATAGGTGAGGGCTCTTACTCAAGTGTC
CATAAAGTAAGAAGGATCTCAGATAACTAAGAATACGCCCTCAAAAAGGTTAAATTATCT
GGTTTAAGCGAAAAAGAGAAAGATAACGCTCTTAATGAGATAAGAATATTAGCAAGTATA
GCTCATCCAAACATGATTGCATATAAGGATGCCTTTTTTGATGAATCTTCTCACTCACTT
TGCATTGTTATGGAGTTAGCCGTCAACGGTGATCTTTCTAAAAAAATTGATAGTGCAAAA
AAAAGAAATAGCTTTGTTCCAGAAGAAGAAATTTGGACAGTAGCGTTGCATATGTTAAGA
GGTTTGAAAGCTATGCACTCCAAAAAGATTCTTCACAGAGACCTCAAGTGTGCAAATGTC
TTTATTTCCAAGCAAGATGAATACAAAATTGGTGATCTCAATGTCTCAAAAGTCGCCAAA
AGAGGACTAGTATACACTTAAACTGGTACTCCTTATTACGCATCACCTGAAGTTTGGGTA
ATTTAGTTTAAAAAATAATTTATACAAATCATGATTTAAATATTTGAAGAGGATTGGTAT
GTTTTTAATTTTTATCAAGCCAATAACATTCAAAAAAAAATGGAAATATATTAAGCAAAT
AAATGAAAGGTTATCTTACCAAATGAATGATGGTACATTTCATTTTACATCTTAGTGCAA
TAATTAGTAATAGTTTTGATAAATAGAATTAAAGAACAAGTTAACAAACAAACAACAAAT
TCCTATTGATTTATTAACTACTTTGTCAAAAATAACTCTTATTTAATCTTTGATTCTATT
TTTTACGTTCCATTCAATTTGCTATTAAAAATAGAATTTTTAAATTTTAAGAGATTCTTT
AAGATATTATCTTAATTGCGTTTCTTTTTTCAGTCAATCTTTGATTTAATCGTTCATGAA
TGAAATGTTATATATTATTGCTGCCTTTATAGAATAACAAATACAAAAAAAATTATAAAT
TTTAACTCATTATCAAATCTAAAAGCTAATTAATTCCTTAATTTGTTTGGACTAAAGAGA
AGCAACGCACATATAAAAAAATTTATAATTTTAAAATCAAGCAAGATAAATTTTAAAGAG
TTTATTTTTGAGGGTAGCATAGATCAATTAATTCATAAGAAATTTTTAAATATACTGAAT
AGAAATTTAATCATAAATTAATTCTAGAATAAAAAAATCCTCTTATTTTTTATGATGAAA
AATAATTAAATATACAAATAAATTAATAACTATATTTTTTATTTTAGAGAGATGAACCAT
ATGACAGTTCAAGCGATATTTGGTCATTTGGATGCATTTTATACGAATTAGCAGCTCTTA
ATCCACCATTTAGAGCTAAAGATATGGAAGGATTGTATAAAAAAGTATAGAAAGGTATAT
TTGAGAGAATTCCATAAAGATATTCTAATGATTTGTAGAAGTTTATTGCATTATGCCTTT
AGGTTAGTAGTGTATAACGTCCTTCTGTTACTTAGCTTTTAAACAATGTACTTCTTAAGC
GTAATACCTAATTTTTAGCAGAATCTCCTGAAGAGTAATAAGATAAGGAAAACACCCTTA
GCCCAGAAGACCTTTTAAACACAATCAAAATGCCTAAAAACCCTCGTTAGCTTAAGGAAA
AGCTCCCAAAGCCTTAATATGATAAAGAGATATTAAATAATTCATATGATGGAGAAATAC
AACGCAAGGAGCGTAACCACAATAGGAATATGTCTGTAAAAATGAATAGGATATAATCTG
TAACCAACCATAAATAGCATTAATACCTATAATAGTAATAGCAACTAATGTTGGAGTAGG
AAGGAAAAGATGTTGTTTTACCTTTAATTCCCAGATCATAATAATAAAAAATATTAGAAC
CTATAAGTAACAGCTAGTTACAGGCATAACAAAATAATAGCAATATTATAGGTAGCTAAA
ATGATATTTATTCTAGAATAGGTAGCAACAGATATGAAAATTCTTCATCCATAGTTAGTG
ATTCCAGAAATTACTTGCAGGAAATACAGCCAAAAAAGCGAATTAATTAAAATGGTTCAA
GTGGTAACTACAATGAAGATTACTCCTAAAAATATAATAGATATGATTAACAACCAAGGT
CAATAAACTCTCCAACTATATCTGTAATTTCTAAAAAGGATACAGGGTATTCAAATCCAG
TGAACTCCATTAATCCACTAAGAAACAGAGTTAATTCTATAAATCAAATCAATAGTTATG
CAAGAATAGCTAATTTATATTAAAATTCTAAAAATCCCTATAACAACTACAGCGGAAATT
CGATGCAGAGTGTTTCAATCGACTACAATCCTTAATATTCTCGTCCTGTTTGGTGGGGTT
GA

>TTHERM_00245740(protein)
MSLKDFVNLQKIGEGSYSSVHKVRRISDNQEYALKKVKLSGLSEKEKDNALNEIRILASI
AHPNMIAYKDAFFDESSHSLCIVMELAVNGDLSKKIDSAKKRNSFVPEEEIWTVALHMLR
GLKAMHSKKILHRDLKCANVFISKQDEYKIGDLNVSKVAKRGLVYTQTGTPYYASPEVWR
DEPYDSSSDIWSFGCILYELAALNPPFRAKDMEGLYKKVQKGIFERIPQRYSNDLQKFIA
LCLQVSSVQRPSVTQLLNNVLLKRNTQFLAESPEEQQDKENTLSPEDLLNTIKMPKNPRQ
LKEKLPKPQYDKEILNNSYDGEIQRKERNHNRNMSVKMNRIQSVTNHKQHQYLQQQQQLM
LEQEGKDVVLPLIPRSQQQKILEPISNSQLQAQQNNSNIIGSQNDIYSRIGSNRYENSSS
IVSDSRNYLQEIQPKKRINQNGSSGNYNEDYSQKYNRYDQQPRSINSPTISVISKKDTGY
SNPVNSINPLRNRVNSINQINSYARIANLYQNSKNPYNNYSGNSMQSVSIDYNPQYSRPV
WWG