Identifiers and Description

Gene Model Identifier

TTHERM_00248420

Standard Name

FZY1 (FiZzY 1)

Aliases

PreTt02538 | 21.m00369

Description

FZY1 WD domain G-beta repeat protein; Fizzy/CDC20/CDH1 family protein; homolog of S. cerevisiae CDC20- a cell cycle regulated activator of the anaphase-promoting complex /cyclosome (APC/C)- which directs ubiquitination of various targets

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00400 ) WD domain, G-beta repeat
• ( PF08662 ) Eukaryotic translation initiation factor eIF2A

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_00459.1	9.997093137033517e-262
	Description: hypothetical protein (570 aa)
Oxytricha	Contig16130.0.g41	1.999447289884935e-116
	Description: WD domain, G-beta repeat
DictyBase	DDB_G0285601	1.0001155149984988e-113
	Description: cdc20 on chromosome: 4 position 3433247 to 3434746
WormBase	WBGene00001510	1.9991716194688635e-85
	Description: locus:fzr-1 status:Partially_confirmed UniProt:Q09649 protein_id:CAA87433.1
WormBase	WBGene00002223	1.9991716194688635e-85
	Description: locus:klp-12 status:Confirmed UniProt:G5EFJ0 protein_id:CAN86600.1
SGD	YGL003C	8.002927718340724e-80
	Description: CDH1 Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p
Stentor Coeruleus	SteCoe_20239	1.0112214926104486e-43
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00248420(coding)
ATGTTTTGGAAGGATGAAAACGTTTTTAAAAATAAGCATTCAGTAGGAAACAATCCACTC
TTTGGTGGTAAAGAAAAGCCTGCTTAGTCAGATTGTAGATTTATCCCAAGTAGAAGAGGA
ACTAACACATCTTACAATTAATATTTACTCAAAGAGAATATCAACACATAAAACATCATA
AATTAAAACGGTTCATGCATTTCCTAAAACTTTGAAACATCTTCTCAAACTTCATCAACA
ACAGCTACTACTCAAAGCAGCTTTTTCCACTTCGGTACCTCAGGATCAGGCAATATTTTC
AATCAACAATAAAGCTAACAACAATCAGGAGTAATCAATTCTGATGAATAAACTACTAAC
AGCAATTAGTCTATGATTCATAATGCTAGTTCATCCTCTTCCACTTAAACTTCAGGTATA
AATAGCAGTAATCTGAATATTAGTTACTGCAATAGCAGCGTAAACTCATACCAGAAGCTG
ATGGAAGACTGCCTCTTTTAGCAGGAAAAGAAAAATCAAAAAAAAAGAGTGTTAAATTTT
AGAAGTGAATCAGACATGCCAATTCCTTTGGACAAGTGCATTAGTAAGACTTTTGAGTAA
GCAAATCAACAATTCATGGAAACAAATAAAATAATGAGATATATTTCTCCTATGCCAGAA
AGAATACTTGATGCACCTTAACTTAGCGATGATTACTACCTTAATTTAATGGATTGGGGA
GACAGTGGTACTGACAATAAAGGCACTTTAGCAATATGTCTTGGAAGCGAAGTTTATTTA
TGGGATGAATATGAAATCATAAACCTTTTTAAGGCTAATTAAAATATTTAGGCTACTAGT
GTCAGCTGGATGAATTTAAAAAAGAAAAATTGCTTGGCCGTTGGCTTCTCTGATAATACA
ATATAGCTTTGGGATACTGAAAAGTGCATTCCATACAGAATTCTCAAAGGTCATACCGGT
AGAGTATCTTCACTATCCTGGAATAATTACATATTGTCAAGTGGAAGCAGAGACACTTAA
ATAATTAATCACGACATTCGTTAAAAAAATAATATAATAAAGCGCTTTTAAGGCCATGAA
TAGGAGGTATGTGGATTAAAGTGGTCTCCCGATGGTACTCAGCTAGCTTCAGGAGGTAAC
GATAATACACTCAGAATTTGGGATATTAATTATGCTTAAAATAATATCAACAACAATAAC
ACCTCTAGTTCAAGTAGTTAGAGTGCTTCTCCAAGTTATCAGCGTGCCTGTTTTTATAAT
CACAAAGCAGCTGTAAAGGCTCTAGCATGGTGTCCTTGGTAAAAAAATCTTTTAGCAAGT
GGAGGGGGAACCTAGGATAAAACAATTAAGTTCTGGAATACTGATAAAATGGAATTAGTC
AATTCAATCAACTGTGGTAGTTAGGTATGCTCAATTTTATGGAATCCTTAGGACAAAGAA
CTCATAAGCTCTCATGGGTTCTAAGATAACTAATTGATTGTTTGGAGTTACCCATCGATG
CAGAAAATTACTGAGTTACATGGACATACAAATAGAGTGTTACATATGGCGCTTTCTCCA
GATGGTTCTACCGTATGCTCAGCCTCTTCCGACGAAACCTTAAGATTTTGGAAGGTCTTC
CCTGGTTCTAGATATGATAGACATGATTATGATGACTCGAATCCGTTCACAAAACACAAA
AGAGATGGATTATCTTCATAAAATCTATTCATCAGATGA

>TTHERM_00248420(gene)
ATGTTTTGGAAGGATGAAAACGTTTTTAAAAATAAGCATTCAGTAGGAAACAATCCACTC
TTTGGTGGTAAAGAAAAGCCTGCTTAGTCAGTAATAAATACTTCATTTTCTAGTTTCTCC
TTTTACTGTAAAAGGAGTGTTTGATAACATTACGCTCTTTTAATTATGCCCAATTATTAA
AAGCTTCAATCTTTTGGACGTTCCAATCAATGATCGACTTACAAAAGGAGGCGAATATTA
AAATAGAAGTGGCTGATTAAAGGAGTTTGTTTAAACATTCTATTAAATGGCTCTTTAATA
AATCTTATGACATTTTTGTTTTTTTATATAAAGGATTGTAGATTTATCCCAAGTAGAAGA
GGAACTAACACATCTTACAATTAATATTTACTCAAAGAGAATATCAACACATAAAACATC
ATAAATTAAAACGGTTCATGCATTTCCTAAAACTTTGAAACATCTTCTCAAACTTCATCA
ACAACAGCTACTACTCAAAGCAGCTTTTTCCACTTCGGTACCTCAGGATCAGGCAATATT
TTCAATCAACAATAAAGCTAACAACAATCAGGAGTAATCAATTCTGATGAATAAACTACT
AACAGCAATTAGTCTATGATTCATAATGCTAGTTCATCCTCTTCCACTTAAACTTCAGGT
ATAAATAGCAGTAATCTGAATATTAGTTACTGCAATAGCAGCGTAAACTCATACCAGAAG
CTGATGGAAGACTGCCTCTTTTAGCAGGAAAAGAAAAATCAAAAAAAAAGAGTGTTAAAT
TTTAGAAGTGAATCAGACATGCCAATTCCTTTGGACAAGTGCATTAGTAAGACTTTTGAG
TAAGCAAATCAACAATTCATGGAAACAAATAAAATAATGAGATATATTTCTCCTATGCCA
GAAAGAATACTTGATGCACCTTAACTTAGCGATGATTACTACCTTAATTTAATGGATTGG
GGAGACAGTGGTACTGACAATAAAGGCACTTTAGCAATATGTCTTGGAAGCGAAGTTTAT
TTATGGGATGAATATGAAATCATAAACCTTTTTAAGGCTAATTAAAATATTTAGGCTACT
AGTGTCAGCTGGATGAATTTAAAAAAGAAAAATTGCTTGGCCGTTGGCTTCTCTGATAAT
ACAATATAGCTTTGGGATACTGAAAAGTGCATTCCATACAGAATTCTCAAAGGTCATACC
GGTAGAGTATCTTCACTATCCTGGAATAATTACATATTGTCAAGTGGAAGCAGAGACACT
TAAATAATTAATCACGACATTCGTTAAAAAAATAATATAATAAAGCGCTTTTAAGGCCAT
GAATAGGAGGTATGTGGATTAAAGTGGTCTCCCGATGGTACTCAGCTAGCTTCAGGAGGT
AACGATAATACACTCAGAATTTGGGATATTAATTATGCTTAAAATAATATCAACAACAAT
AACACCTCTAGTTCAAGTAGTTAGAGTGCTTCTCCAAGTTATCAGCGTGCCTGTTTTTAT
AATCACAAAGCAGCTGTAAAGGCTCTAGCATGGTGTCCTTGGTAAAAAAATCTTTTAGCA
AGTGGAGGGGGAACCTAGGATAAAACAATTAAGTTCTGGAATACTGATAAAATGGAATTA
GTCAATTCAATCAACTGTGGTAGTTAGGTATGCTCAATTTTATGGAATCCTTAGGACAAA
GAACTCATAAGCTCTCATGGGTTCTAAGATAACTAATTGATTGTTTGGAGTTACCCATCG
ATGCAGAAAATTACTGAGTTACATGGACATACAAATAGAGTGTTACATATGGCGCTTTCT
CCAGATGGTTCTACCGTATGCTCAGCCTCTTCCGACGAAACCTTAAGATTTTGGAAGGTC
TTCCCTGGTTCTAGATATGATAGACATGATTATGATGACTCGAATCCGTTCACAAAACAC
AAAAGAGATGGATTATCTTCATAAAATCTATTCATCAGATGA

>TTHERM_00248420(protein)
MFWKDENVFKNKHSVGNNPLFGGKEKPAQSDCRFIPSRRGTNTSYNQYLLKENINTQNII
NQNGSCISQNFETSSQTSSTTATTQSSFFHFGTSGSGNIFNQQQSQQQSGVINSDEQTTN
SNQSMIHNASSSSSTQTSGINSSNLNISYCNSSVNSYQKLMEDCLFQQEKKNQKKRVLNF
RSESDMPIPLDKCISKTFEQANQQFMETNKIMRYISPMPERILDAPQLSDDYYLNLMDWG
DSGTDNKGTLAICLGSEVYLWDEYEIINLFKANQNIQATSVSWMNLKKKNCLAVGFSDNT
IQLWDTEKCIPYRILKGHTGRVSSLSWNNYILSSGSRDTQIINHDIRQKNNIIKRFQGHE
QEVCGLKWSPDGTQLASGGNDNTLRIWDINYAQNNINNNNTSSSSSQSASPSYQRACFYN
HKAAVKALAWCPWQKNLLASGGGTQDKTIKFWNTDKMELVNSINCGSQVCSILWNPQDKE
LISSHGFQDNQLIVWSYPSMQKITELHGHTNRVLHMALSPDGSTVCSASSDETLRFWKVF
PGSRYDRHDYDDSNPFTKHKRDGLSSQNLFIR