Identifiers and Description

Gene Model Identifier

TTHERM_00260770

Standard Name

NRK14 (NIMA-Related Kinase)

Aliases

PreTt29340 | 23.m00236

Description

NRK14 Serine/Threonine kinase domain protein; NIMA-Related Kinase; NEK Ser/Thr protein kinase family, NIMA subfamily

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• aleurone grain membrane (IEA) | GO:0032578
• clathrin-sculpted acetylcholine transport vesicle lumen (IEA) | GO:0060202
• CURI complex (IEA) | GO:0032545
• EGFR-Grb2-Sos complex (IEA) | GO:0070620
• multivesicular body (IEA) | GO:0005771
• obsolete endocytotic transport vesicle (IEA) | GO:0005810
• vacuolar membrane (IEA) | GO:0005774

Molecular Function

• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• ABC-type maltose transporter activity (IEA) | GO:0015423
• ABC-type oligosaccharide transporter activity (IEA) | GO:0015422
• aromatase activity (IEA) | GO:0008402
• arsenate reductase (glutaredoxin) activity (IEA) | GO:0008794
• axon guidance receptor activity (IEA) | GO:0008046
• carboxymethylenebutenolidase activity (IEA) | GO:0008806
• Cys-tRNA(Pro) hydrolase activity (IEA) | GO:0043907
• ferric triacetylfusarinine C:proton symporter activity (IEA) | GO:0015346
• microtubule severing ATPase activity (IEA) | GO:0008568
• N-acetyl-gamma-aminoadipyl-phosphate reductase activity (IEA) | GO:0043870
• obsolete D-lysine oxidase activity (IEA) | GO:0043912
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• phosphatidylcholine:cardiolipin O-linoleoyltransferase activity (IEA) | GO:0032577
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• rhamnulose-1-phosphate aldolase activity (IEA) | GO:0008994
• Ser(Gly)-tRNA(Ala) hydrolase activity (IEA) | GO:0043908
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• sterol 14-demethylase activity (IEA) | GO:0008398
• tubulin-glutamic acid ligase activity (IEA) | GO:0070740

Biological Process

• 1-undecene metabolic process (IEA) | GO:1902820
• bud dilation involved in lung branching (IEA) | GO:0060503
• cell migration in diencephalon (IEA) | GO:0061381
• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• cellular response to D-galactose (IEA) | GO:1905378
• cellular response to phosphate starvation (IEA) | GO:0016036
• epithelial cell proliferation involved in lung bud dilation (IEA) | GO:0060505
• epithelium development (IEA) | GO:0060429
• ethyl acetate biosynthetic process (IEA) | GO:1902819
• female courtship behavior (IEA) | GO:0008050
• germinal center formation (IEA) | GO:0002467
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• inferior colliculus development (IEA) | GO:0061379
• interleukin-28A secretion (IEA) | GO:0072628
• laminaritriose transport (IEA) | GO:2001097
• lung connective tissue development (IEA) | GO:0060427
• mesonephric podocyte cell fate commitment (IEA) | GO:0061258
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of double-strand break repair via nonhomologous end joining (IEA) | GO:2001033
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• obsolete activation of MAPKK activity (IEA) | GO:0000186
• obsolete fertilization, exchange of chromosomal proteins (IEA) | GO:0035042
• obsolete negative regulation of response to extracellular stimulus (IEA) | GO:0032105
• obsolete nuclear translocation of MAPK during sporulation (sensu Saccharomyces) (IEA) | GO:0000207
• obsolete positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process (IEA) | GO:1902964
• obsolete regulation of glucose-6-phosphatase activity (IEA) | GO:0032114
• ommochrome biosynthetic process (IEA) | GO:0006727
• peripheral tolerance induction (IEA) | GO:0002465
• phagocytosis (IEA) | GO:0006909
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation of intestinal epithelial cell development (IEA) | GO:1905300
• positive regulation of late endosome to lysosome transport (IEA) | GO:1902824
• positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
• positive regulation of protein autoubiquitination (IEA) | GO:1902499
• positive regulation of response to water deprivation (IEA) | GO:1902584
• positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
• priming of cellular response to stress (IEA) | GO:0080136
• protein localization to old growing cell tip (IEA) | GO:1903858
• quercetin biosynthetic process (IEA) | GO:1901734
• quercetin metabolic process (IEA) | GO:1901732
• regulation of cellular glucuronidation (IEA) | GO:2001029
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of L-arginine import into cell (IEA) | GO:1902826
• regulation of late endosome to lysosome transport (IEA) | GO:1902822
• regulation of macropinocytosis (IEA) | GO:1905301
• release of sequestered calcium ion into cytosol by endoplasmic reticulum (IEA) | GO:1903514
• sperm aster formation (IEA) | GO:0035044
• synaptic vesicle docking (IEA) | GO:0016081
• tetrasaccharide transport (IEA) | GO:2001098
• xanthophyll biosynthetic process (IEA) | GO:0016123
• xanthophyll catabolic process (IEA) | GO:0016124

Domains

• ( PF00069 ) Protein kinase domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00260770(coding)
ATGTCATCTCAAAATCAATAATCTAATCATTTTAATATACCAGACGGCTATCGATGGATT
AAAAAAATAGGCGAAGGTGCATATGGTTAAGTGCATTTGGTGTAAAGCATTAGAGATGGT
AGTAAATGGGCGATAAAAAATATATATGTTAGTGGAGGTGAAGATGTGAAAAAAAAACGC
TAATCTGAATACAAAATCCTTAAGAAGCTTGATAATCCTCATATAATTAAGTTCAAGGAG
GCTATTAATTATAGAAATTAATAATTGATTTAGATCATTATGGAATACACAGATGGTGGA
GACTTAGAAAAACTAATAGAAAAATAAAAATAAAGTGCAAAACCATTTGAAGAAGAGAAA
ATTTTAGATTTTTTTATTCAAATTTGCTTGGGCTTGGATTGCATACACAAAAATAAAATA
ATTCATAGAGATATCAAACCTGCAAATATATTTTTAACTGCTTTTGGTTAATTGAAAATT
GGTGATTTCGGAGTATCAAAAGAACTTTAATACACTAAATAATGTCTAAAAACAATAGTT
GGGACTCCGTACTATATAGCTCCAGAAATTGTAAGTGGATATGCATATAATTCAAGTGTT
GATATTTGGTCTTTAGGTGTTATTCTATATTAGCTGTGTTGTCTTTAACCACCTTTTTAA
GACTGGAATGAAGCAAATCTTTACTGTAAAATTAAAAAAAAACCCTATCCACCTATAGCT
TAACTTTATTACTCAGGAAAACTTAAAACATTAATATCTAAACTCCTGAGAAAATGCCCA
AAGGAACGCTATACTTTAAAATAAATATTCGACGAATCTTTAATTTAAAGTAGACTCAAA
GTATACTTAAAAAAATCCATTTTAAATAGATCTCCTGATATACCTTAGGTAAATAATTTT
ATGGAGCAAGACTCATTATTGAATCAATTCATATAGAATGATCACTTGTAAGAAAATAGA
TAAGAAATTAACCAATAACCTGTTAATAGCAATGTAAATTAATAAAATATCAATCCAACT
TCTGCTAATAACTAAAATTTCGAAAGTAATAATAATTAATTAAATGAGCTTAGGCCATAA
AGTTGTGCCAATAGGTAAGCTTAAGAAGAATAAAAAAATGAATCTGCTGATAGGAGAAAA
AACTTACAAAAACTTGACAAATAAGAGTAATCAAATTTAGAAGAAAAAAATGCACAGAAT
AATAATAATAATAATAATATAGAAAATAATACAATTCCAGCTAGTCCATAAGTAAAGAAT
TTTAACACTTTAAAAAATGAAAATAACACTCATCTAAGTGGAAAGAGTACTTCATAAAGT
AGTTAAATATCGGACTTAGAAACACCTGTCGCAGAGAAAAAGGTGTAGCATTGTCGATCA
TCAGTTATAATAAAAATTAAAAACATTACTGATTAGAGAAATGAGTAAAATCAAAAAAGT
TAAGATAACCCTTTTATTTTACCAAATCAATAATAAAATAAAAAAGATAATCTTTAGTAG
TTTAAATCAAAATCAGTTATTGTATTCAATGAAAGAGATTTCTTTTGTAATAAATAAATA
TTGCCACCTCTAACATAAATACAAAAAATAGAAATCGAAAAAGAAAATGTAAATCAAAAT
CATTTGAATGAAGATTTATAAAAATAAATTTAAGTAAACAGAAAATATGAAAACATATTT
AGTACACATTAAAAATAAATCAGTGGCTTAGATAAATAAAATATTCAATATGAAAAAAAA
ATAAAATCGAACCTCAATTAGGTTGATAAATTCCCAATAACTCCAACCAAACCAGATTAA
AAAGATTTGAACACAAAATAAAATGGTAATTCTTAAGAACAAAAAAATATTTCTAAAGCA
AAAAGAAATAATTTTAATGAATAAGAATTCAACACTCATTCTTGTTAATTATTGACCGGA
AAAAAAAAAAATTTTGTAGATAAGGAGCAGTCACAAGAGAAGAATTCCAAGGTTCTATTT
GAATAAAAAACTCAAAAAGATATTTGTCTTGAGAAATAATCGTCTAAAAATAACATGATT
AGAGAGCTAAATTAATTTTAAGTACCTTATTCAGAAGATGAATACATCAAATACCTGACG
TGTTTAATTTAAAGTGAACCAAATTATGTCAAAGAAACCTATAATGAGGAAGATTTACTT
TAGGAAAATGATCTTAAACTAATAGATGATGAAGATTTTTATTATGATGATTACTTTGAA
GAAGAAGAAGAAGAAGTAGAAGAAGAAGAAAAAATAAATAAATAACAAGAAAGAGATGTA
GAAAAGATTTATAACATTCCAAGATAATCACAAGAATAATTTAATTAATTGAAGGAAGAT
TTCTTTAAAAAAATGACACAAGAGTAATTCAAACTACTTTACAACATAGTAAATAAGGAG
ATGTAAAATTAAGACTTCTTAGATGATACACTAAAGAACTAAATAAAGATATTATAAAAA
AAGATTCTCTCAGTTGAACTAGATGAATTAAAGTATAAAATATAATAATTAATTTATCTA
TTAAGTTAAGATTGA

>TTHERM_00260770(gene)
ATTTGATTATGTGTAGAGATTTAAAAAACTAAGTAAAAGATAAAGAAGATTAGATCAATT
AGAATAATATAAATTTTAGAGAAAAAATACTAATTTCTTCAAAAAGAAAGTCAAACATAT
TAAAAAAATCAACTTAGTTAATAATTGAACTAAAGGACTGAGGGAGGAGCTATGTCATCT
CAAAATCAATAATCTAATCATTTTAATATACCAGACGGCTATCGATGGATTAAAAAAATA
GGCGAAGGTGCATATGGTTAAGTGCATTTGGTGTAAAGCATTAGAGATGGTAGTAAATGG
GCGATAAAAAATATATATGTTAGTGGAGGTGAAGATGTGAAAAAAAAACGCTAATCTGAA
TACAAAATCCTTAAGAAGCTTGATAATCCTCATATAATTAAGTTCAAGGAGGCTATTAAT
TATAGAAATTAATAATTGATTTAGATCATTATGGAATACACAGATGGTGGAGACTTAGAA
AAACTAATAGAAAAATAAAAATAAAGTGCAAAACCATTTGAAGAAGAGAAAATTTTAGAT
TTTTTTATTCAAATTTGCTTGGGCTTGGATTGCATACACAAAAATAAAATAATTCATAGA
GATATCAAACCTGCAAATATATTTTTAACTGCTTTTGGTTAATTGAAAATTGGTGATTTC
GGAGTATCAAAAGAACTTTAATACACTAAATAATGTCTAAAAACAATAGTTGGGACTCCG
TACTATATAGCTCCAGAAATTGTAAGTGGATATGCATATAATTCAAGTGTTGATATTTGG
TCTTTAGGTGTTATTCTATATTAGCTGTGTTGTCTTTAACCACCTTTTTAAGACTGGAAT
GAAGCAAATCTTTACTGTAAAATTAAAAAAAAACCCTATCCACCTATAGCTTAACTTTAT
TACTCAGGAAAACTTAAAACATTAATATCTAAACTCCTGAGAAAATGCCCAAAGGAACGC
TATACTTTAAAATAAATATTCGACGAATCTTTAATTTAAAGTAGACTCAAAGTATACTTA
AAAAAATCCATTTTAAATAGATCTCCTGATATACCTTAGGTAAATAATTTTATGGAGCAA
GACTCATTATTGAATCAATTCATATAGAATGATCACTTGTAAGAAAATAGATAAGAAATT
AACCAATAACCTGTTAATAGCAATGTAAATTAATAAAATATCAATCCAACTTCTGCTAAT
AACTAAAATTTCGAAAGTAATAATAATTAATTAAATGAGCTTAGGCCATAAAGTTGTGCC
AATAGGTAAGCTTAAGAAGAATAAAAAAATGAATCTGCTGATAGGAGAAAAAACTTACAA
AAACTTGACAAATAAGAGTAATCAAATTTAGAAGAAAAAAATGCACAGAATAATAATAAT
AATAATAATATAGAAAATAATACAATTCCAGCTAGTCCATAAGTAAAGAATTTTAACACT
TTAAAAAATGAAAATAACACTCATCTAAGTGGAAAGAGTACTTCATAAAGTAGTTAAATA
TCGGACTTAGAAACACCTGTCGCAGAGAAAAAGGTGTAGCATTGTCGATCATCAGTTATA
ATAAAAATTAAAAACATTACTGATTAGAGAAATGAGTAAAATCAAAAAAGTTAAGATAAC
CCTTTTATTTTACCAAATCAATAATAAAATAAAAAAGATAATCTTTAGTAGTTTAAATCA
AAATCAGTTATTGTATTCAATGAAAGAGATTTCTTTTGTAATAAATAAATATTGCCACCT
CTAACATAAATACAAAAAATAGAAATCGAAAAAGAAAATGTAAATCAAAATCATTTGAAT
GAAGATTTATAAAAATAAATTTAAGTAAACAGAAAATATGAAAACATATTTAGTACACAT
TAAAAATAAATCAGTGGCTTAGATAAATAAAATATTCAATATGAAAAAAAAATAAAATCG
AACCTCAATTAGGTTGATAAATTCCCAATAACTCCAACCAAACCAGATTAAAAAGATTTG
AACACAAAATAAAATGGTAATTCTTAAGAACAAAAAAATATTTCTAAAGCAAAAAGAAAT
AATTTTAATGAATAAGAATTCAACACTCATTCTTGTTAATTATTGACCGGAAAAAAAAAA
AATTTTGTAGATAAGGAGCAGTCACAAGAGAAGAATTCCAAGGTTCTATTTGAATAAAAA
ACTCAAAAAGATATTTGTCTTGAGAAATAATCGTCTAAAAATAACATGATTAGAGAGCTA
AATTAATTTTAAGTACCTTATTCAGAAGATGAATACATCAAATACCTGACGTGTTTAATT
TAAAGTGAACCAAATTATGTCAAAGAAACCTATAATGAGGAAGATTTACTTTAGGAAAAT
GATCTTAAACTAATAGATGATGAAGATTTTTATTATGATGATTACTTTGAAGAAGAAGAA
GAAGAAGTAGAAGAAGAAGAAAAAATAAATAAATAACAAGAAAGAGATGTAGAAAAGATT
TATAACATTCCAAGATAATCACAAGAATAATTTAATTAATTGAAGGAAGATTTCTTTAAA
AAAATGACACAAGAGTAATTCAAACTACTTTACAACATAGTAAATAAGGAGATGTAAAAT
TAAGACTTCTTAGATGATACACTAAAGAACTAAATAAAGATATTATAAAAAAAGATTCTC
TCAGTTGAACTAGATGAATTAAAGTATAAAATATAATAATTAATTTATCTATTAAGTTAA
GATTGAAAATAGTGATTTTTATATTCAATATTTTTCACTATTTTTCTTTCAAGTTTTGAA
AAAGAAAAAAGTGGAATTAAAAACTTAAAAATTGAATTGGTTCTTACTTGTAACTATGAT
TTAGAGATTATATAAA

>TTHERM_00260770(protein)
MSSQNQQSNHFNIPDGYRWIKKIGEGAYGQVHLVQSIRDGSKWAIKNIYVSGGEDVKKKR
QSEYKILKKLDNPHIIKFKEAINYRNQQLIQIIMEYTDGGDLEKLIEKQKQSAKPFEEEK
ILDFFIQICLGLDCIHKNKIIHRDIKPANIFLTAFGQLKIGDFGVSKELQYTKQCLKTIV
GTPYYIAPEIVSGYAYNSSVDIWSLGVILYQLCCLQPPFQDWNEANLYCKIKKKPYPPIA
QLYYSGKLKTLISKLLRKCPKERYTLKQIFDESLIQSRLKVYLKKSILNRSPDIPQVNNF
MEQDSLLNQFIQNDHLQENRQEINQQPVNSNVNQQNINPTSANNQNFESNNNQLNELRPQ
SCANRQAQEEQKNESADRRKNLQKLDKQEQSNLEEKNAQNNNNNNNIENNTIPASPQVKN
FNTLKNENNTHLSGKSTSQSSQISDLETPVAEKKVQHCRSSVIIKIKNITDQRNEQNQKS
QDNPFILPNQQQNKKDNLQQFKSKSVIVFNERDFFCNKQILPPLTQIQKIEIEKENVNQN
HLNEDLQKQIQVNRKYENIFSTHQKQISGLDKQNIQYEKKIKSNLNQVDKFPITPTKPDQ
KDLNTKQNGNSQEQKNISKAKRNNFNEQEFNTHSCQLLTGKKKNFVDKEQSQEKNSKVLF
EQKTQKDICLEKQSSKNNMIRELNQFQVPYSEDEYIKYLTCLIQSEPNYVKETYNEEDLL
QENDLKLIDDEDFYYDDYFEEEEEEVEEEEKINKQQERDVEKIYNIPRQSQEQFNQLKED
FFKKMTQEQFKLLYNIVNKEMQNQDFLDDTLKNQIKILQKKILSVELDELKYKIQQLIYL
LSQD