Identifiers and Description

Gene Model Identifier

TTHERM_00265180

Standard Name

NRK16 (NIMA-Related Kinase)

Aliases

PreTt29473 | 23.m00369

Description

NRK16 Serine/Threonine kinase domain protein; NIMA-Related Kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• phosphorelay response regulator activity (IEA) | GO:0000156
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• phosphorelay signal transduction system (IEA) | GO:0000160
• protein phosphorylation (IEA) | GO:0006468
• regulation of DNA-templated transcription (IEA) | GO:0006355

Domains

• ( PF00069 ) protein kinase domain
• ( PF00072 ) response regulator receiver domain
• ( PF07714 ) protein tyrosine kinase
• ( TIGR01387 ) heavy metal response regulator
• ( TIGR01818 ) nitrogen regulation protein NR(I)
• ( TIGR02154 ) phosphate regulon transcriptional regulatory protein
• ( TIGR02875 ) sporulation transcription factor Spo0A

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_06009.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (835 aa)
Oxytricha	Contig8286.0.g25	1.999765224767555e-159
	Description: Protein kinase domain
Stentor Coeruleus	SteCoe_21781	1.0648786602415064e-63
	Description: None
DictyBase	DDB_G0289277	2.0004062814618821e-57
	Description: nek4 on chromosome: 5 position 2561379 to 2563106
WormBase	WBGene00022631	1.9997255150861791e-53
	Description: locus:nekl-2 status:Confirmed UniProt:O01775 protein_id:CCD64899.1
SGD	YMR001C	6.0018235484001396e-36
	Description: CDC5 Polo-like kinase with multiple functions in mitosis and cytokinesis through substrate phosphorylation, also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_00265180(coding)
ATGGCTGATAAATAATACATGAATATACATGTCCTCGTAGCAGAGGATGACAATTTCTAA
AGGTTAGCTCTTATAGACATTTTAACTCTATGCGATTATTAGGTCACTGCTGTGGAAAAT
GGCAGATTGGCTAGAGATGAGCTTCTGAAATAAGATTCAAATATTGACATAGTTTTATTA
GATTTATATATGCCAGAAATGGATGGATTTGAATTATTAAGTTTAATGCAAGAACATGAA
AATTTACAAAAGATTCCAGTTATCATGATGAGTTCAGATAAAGAAGAAGAAAAGGTGGCA
ACATGTATTGCAAAAGGAGCAAAAGATTACATATTCAAGCCACTAAGAGTACAAAATGTA
AAAGCTATTGCAAAATACGTACAGTACAAAGATTAAGGAGATAAAAATTCTAATCTAGTC
GGAATTTAATAATATAAGGTTCTTAAAACATTAGGTTAAGGTGCTTCAGGAAGCGTAGAG
TTAGTGTAAAAAAATGATGGAAATTTATATGCATTAAAGACTATATCCATGAAATATATG
AATGATACAGAAAAAAGATCTGCTCAATCAGAAGTTACTTTGCTAAAGGTCTTAGTTGCA
CCAACTATTATTCGTTATTATGAAGCATTTGTCTAAAATGATTCAATTTATATAGTTATG
GAATATGCAAAAGAAGGAGCCTTAAGCGATAAAATACAAGAGCATAAAACTAAAGGCATA
AGGATAGATGAAGAAACTATTCTTTACTTTACTGCATAGATCGTCATAGCTTTGTTCTTT
ATGCATTAAAAGAAAATTCTTCATAGAGATATTAAGTCTCAAAATCTTTTTTTAACTAAA
GAAAATGTAGTTAAGCTAGGAGACTTTGGTATTTCTAAAGCTCTTGGAACAAATGCTGAT
TTCACTAAAACCTTGGTAGGAACTCCTTATTTTATGTCTCCTGAAGTGTGTGCTGGTTAA
TCTTATGGAGACAAAGCAGATATTTGGGCTTTAGGTTGTACTCTATATGAAATGGTCATG
CTTCGTAGACCTTTTGATTGTGAAAATATAAACACTCTCTTTACTATGATCAGATAATAA
GACCCTTCTCCTTTGCACGATAACTGCAGTACAGACATTAGAATGCTAATTACTCTCATG
CTTAACAAAGATCCACTAAAAAGACCATTTATTTGGGATTTAGTAAACATTCCAATCATA
AATAAGAATATTAGAAAATATCATTAGCAAGAAGCTCCTGATGATCCCTTTTTGATAGAA
TTATTGAAAAGACCAACTTCAGGTAATCCTCTTTCAATGCCTAATACTCCATCCAACTCT
AACTCCTCCACTTAACCGCCAGCTAACTCTAACTCGGTAGCAAATAACAACTCAAATGTC
TCTAACAACCCATAAGAAGCATAATGTAATACTTTAGAATAAATTAGTAAGGCTATGAGT
GAAGAATTAAAACCTTACGACCAAAAAACAGGAATGTTTCATGTGGAAAGAAATGTAATC
AACGGAAAACAAATTTTTGATTGGTTTAATAAATATTATCCAAATTATCAAACTTCTCAG
CTTGTAGAATTACTCTAAAATTTAGTAGAAAAGAAGTATATTCATCATATATCAGGTCCA
CAGTATGAAGCAAATGTTAATTCATTATTCAGATTCTAATTTGATATGCCTGGTATACCT
TAAAACTATTACAAAATATGGAGCAAATAAGCAAGAGCACCTAGTGATATAATGTAAGAG
ATAATTTAATAGGCTAATTTCGTTCTCTAAGAAATTTGCGAATAATACACAGGAGTGATA
TCAGAAGATAAGCTTATCCAAAGTAAGAAATATACAAAATTCTAGGAAATGGTGTGTGAA
CTTCAAAAAATTTACTTGCAAGACCTTACTTAAGAAGATTAAAGAAAATCTTTCTTCTTG
AATCTGATTTAAATAATGTAATTTCACCAGTTTATGAAAGAAAAGTATGACCATAAAAGA
AATGAATAAAAAAAAAATGTATCAACAATTCTAGATTTGATCTAATCATTTCTTCCATTC
TTTAAAAAATAATAAAAATTTGAGTACAGAATTGGGCATTAAACTTTTTCTATAGAAGAT
GTGAAACATGGAATTCTAAGGTGTAATAAAAAGCATAAAGGAAGTAGCTTCCGTCCATTT
ACTGGAAGCGATGATAAATATCAGCTCATTTAATAGTAAGATTTAAGAGTTCTTATTCTT
TTTAAAGAAGAAAATGCTTCACCTTCACCTTTGCTTTTCATAACACCTGAAACATTTGAG
GAGCAACTGAATCAACTTTGTGCTAAATTTATGAGCAGATTTGTTTGCTATGATAGGGTT
GAGAACGATCTAACTTTGCATAAAATATTTTAAATATATCAAAATGACTTTGGAAAAGAT
TAATCTGATACAATAAAATGGGCTTCGAAATATACTAAGGGTATAGGAAATGTAAACGAT
CTCATATCAAGCATTTAACAAGGAGAAGTCTTTATATAATTCTAAGAAAAGTTTGAAATC
TGA

>TTHERM_00265180(gene)
ATGGCTGATAAATAATACATGAATATACATGTCCTCGTAGCAGAGGATGACAATTTCTAA
AGGTTAGCTCTTATAGACATTTTAACTCTATGCGATTATTAGGTCACTGCTGTGGAAAAT
GGCAGATTGGCTAGAGATGAGCTTCTGAAATAAGATTCAAATATTGACATAGTTTTATTA
GATTTATATATGCCAGAAATGGATGGATTTGAATTATTAAGTTTAATGCAAGAACATGAA
AATTTACAAAAGATTCCAGTTATCATGATGAGTTCAGATAAAGAAGAAGAAAAGGTGGCA
ACATGTATTGCAAAAGGAGCAAAAGATTACATATTCAAGCCACTAAGAGTACAAAATGTA
AAAGGTAAATCAATAAATGTTAATTTATTTCTAAAAAGCGTTTTTCAAAATTTTCCTCTA
TTTTGATAAAATAACCAAATAGGGAAGTAAAATATTTGAATAGCCAAATCAAAAAGATTT
TAAAACAAGTATAATAAGAAAGTTTATATTTTTAAATTTAAGCTTATTAGGTGCTATTGT
TTTTTTATAAGCTGATTAGAAAAAAATAAGAAAATCAATAAATAATATATTTATTCGTTT
ATTAATTTTAAATAGCTATTGCAAAATACGTACAGTACAAAGATTAAGGAGATAAAAATT
CTAATCTAGTCGGAATTTAATAATATAAGGTTCTTAAAACATTAGGTTAAGGTGCTTCAG
GAAGCGTAGAGTTAGTGTAAAAAAATGATGGAAATTTATATGCATTAAAGACTATATCCA
TGAAATATATGAATGATACAGAAAAAAGATCTGCTCAATCAGAAGTTACTTTGCTAAAGG
TCTTAGTTGCACCAACTATTATTCGTTATTATGAAGCATTTGTCTAAAATGATTCAATTT
ATATGTAAATACAGCAAAAAATTATATAATTATGTCATAATTTATTTTTTTAAAATTTGA
TTAGAGTTATGGAATATGCAAAAGAAGGAGCCTTAAGCGATAAAATACAAGAGCATAAAA
CTAAAGGCATAAGGATAGATGAAGAAACTATTCTTTACTTTACTGCATAGATCGTCATAG
CTTTGTTCTTTATGCATTAAAAGAAAATTCTTCATAGAGATATTAAGTCTCAAAATCTTT
TTTTAACTAAAGAAAATGTAGTTAAGCTAGGAGACTTTGGTATTTCTAAAGCTCTTGGAA
CAAATGCTGATTTCACTAAAACCTTGGTAGGAACTCCTTATTTTATGTCTCCTGAAGTGT
GTGCTGGTTAATCTTATGGAGACAAAGCAGATATTTGGGCTTTAGGTTGTACTCTATATG
AAATGGTCATGCTTCGTAGACCTTTTGATTGTGAAAATATAAACACTCTCTTTACTATGA
TCAGATAATAAGTAATTAATTTTTTTATTTTAAGTATAAACTTTGACCAGTTTTAACATT
TGTTAATAGGACCCTTCTCCTTTGCACGATAACTGCAGTACAGACATTAGAATGCTAATT
ACTCTCATGCTTAACAAAGATCCACTAAAAAGACCATTTATTTGGGATTTAGTAAACATT
CCAATCATAAATAAGAATATTAGAAAATATCATTAGCAAGAAGCTCCTGATGATCCCTTT
TTGATAGAATTATTGAAAAGACCAACTTCAGGTAATCCTCTTTCAATGCCTAATACTCCA
TCCAACTCTAACTCCTCCACTTAACCGCCAGCTAACTCTAACTCGGTAGCAAATAACAAC
TCAAATGTCTCTAACAACCCATAAGAAGCATAATGTAATACTTTAGAATAAATTAGTAAG
GCTATGAGTGAAGAATTAAAACCTTACGACCAAAAAACAGGAATGTTTCATGTGGAAAGA
AATGTAATCAACGGAAAACAAATTTTTGATTGGTTTAATAAATATTATCCAAATTATCAA
ACTTCTCAGCTTGTAGAATTACTCTAAAATTTAGTAGAAAAGAAGTATATTCATCATATA
TCAGGTCCACAGTATGAAGCAAATGTTAATTCATTATTCAGATTCTAATTTGATATGCCT
GGTATACCTTAAAACTATTACAAAATATGGAGCAAATAAGCAAGAGCACCTAGTGATATA
ATGTAAGAGATAATTTAATAGGCTAATTTCGTTCTCTAAGAAGTAAAAAATGCATTAATT
AACTAACTAATTCATCTTTTATAAATATTTTTTACATTCTAATAAGATTTGCGAATAATA
CACAGGAGTGATATCAGAAGATAAGCTTATCCAAAGTAAGAAATATACAAAATTCTAGGA
AATGGTGTGTGAACTTCAAAAAATTTACTTGCAAGACCTTACTTAAGAAGATTAAAGAAA
ATCTTTCTTCTTGAATCTGATTTAAATAATGTAATTTCACCAGTTTATGAAAGAAAAGTA
TGACCATAAAAGAAATGAATAAAAAAAAAATGTATCAACAATTCTAGATTTGATCTAATC
ATTTCTTCCATTCTTTAAAAGTAAATTTAAAGAATAAAAAAATAAAGTTCAATAAAAAAT
ATTATTTTATTTATCTAAAAAGAATAATAAAAATTTGAGTACAGAATTGGGCATTAAACT
TTTTCTATAGAAGATGTGAAACATGGAATTCTAAGGTGTAATAAAAAGCATAAAGGAAGT
AGCTTCCGTCCATTTACTGGAAGCGATGATAAATATCAGCTCATTTAATAGTAAGATTTA
AGAGTTCTTATTCTTTTTAAAGAAGAAAATGCTTCACCTTCACCTTTGCTTTTCATAACA
CCTGAAACATTTGAGGAGCAACTGAATCAACTTTGTGCTAAATTTATGAGCAGATTTGTT
TGCTATGATAGGGTTGAGAACGATCTAACTTTGCATAAAATATTTTAAATATATCAAAAT
GACTTTGGAAAAGATTAATCTGATACAATAAAATGGGCTTCGAAATATACTAAGGGTATA
GGAAATGTAAACGATCTCATATCAAGCATTTAACAAGGAGAAGTCTTTATATAATTCTAA
GAAAAGTTTGAAATCTGA

>TTHERM_00265180(protein)
MADKQYMNIHVLVAEDDNFQRLALIDILTLCDYQVTAVENGRLARDELLKQDSNIDIVLL
DLYMPEMDGFELLSLMQEHENLQKIPVIMMSSDKEEEKVATCIAKGAKDYIFKPLRVQNV
KAIAKYVQYKDQGDKNSNLVGIQQYKVLKTLGQGASGSVELVQKNDGNLYALKTISMKYM
NDTEKRSAQSEVTLLKVLVAPTIIRYYEAFVQNDSIYIVMEYAKEGALSDKIQEHKTKGI
RIDEETILYFTAQIVIALFFMHQKKILHRDIKSQNLFLTKENVVKLGDFGISKALGTNAD
FTKTLVGTPYFMSPEVCAGQSYGDKADIWALGCTLYEMVMLRRPFDCENINTLFTMIRQQ
DPSPLHDNCSTDIRMLITLMLNKDPLKRPFIWDLVNIPIINKNIRKYHQQEAPDDPFLIE
LLKRPTSGNPLSMPNTPSNSNSSTQPPANSNSVANNNSNVSNNPQEAQCNTLEQISKAMS
EELKPYDQKTGMFHVERNVINGKQIFDWFNKYYPNYQTSQLVELLQNLVEKKYIHHISGP
QYEANVNSLFRFQFDMPGIPQNYYKIWSKQARAPSDIMQEIIQQANFVLQEICEQYTGVI
SEDKLIQSKKYTKFQEMVCELQKIYLQDLTQEDQRKSFFLNLIQIMQFHQFMKEKYDHKR
NEQKKNVSTILDLIQSFLPFFKKQQKFEYRIGHQTFSIEDVKHGILRCNKKHKGSSFRPF
TGSDDKYQLIQQQDLRVLILFKEENASPSPLLFITPETFEEQLNQLCAKFMSRFVCYDRV
ENDLTLHKIFQIYQNDFGKDQSDTIKWASKYTKGIGNVNDLISSIQQGEVFIQFQEKFEI