Identifiers and Description

Gene Model Identifier

TTHERM_00279750

Standard Name

GTP1 (GTPase 1 )

Aliases

TGP1 | PreTt04816 | 25.m00280 | 3694.m00065 | Rab8A

Description

GTP1 ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Rab VIII family protein; small monomeric GTPase that regulates membrane fusion and fission events; putative intermediate compartment protein; putative involvement in regulated secretion

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase-mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00025 ) ADP-ribosylation factor family
• ( PF00071 ) Ras family
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00231 ) small GTP-binding protein domain
• ( TIGR02528 ) ethanolamine utilization protein, EutP

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_08923.1	3.999453553586398e-137
	Description: Ras family protein (205 aa)
Oxytricha	Contig7494.0.g64	3.0000115468388957e-66
	Description: Ras family
WormBase	WBGene00004273	1.9997677415930956e-65
	Description: locus:rab-10 status:Confirmed UniProt:Q94148 protein_id:CCD70773.1
DictyBase	DDB_G0276399	1.9997677415930956e-65
	Description: rab8B on chromosome: 2 position 6878753 to 6879364
WormBase	WBGene00000383	1.9997677415930956e-65
	Description: locus:cdc-14 Probable tyrosine-protein phosphatase cdc-14 status:Confirmed UniProt:P81299 protein_id:CCD64955.1
SGD	YFL005W	2.0007467515522948e-59
	Description: SEC4 Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane
Stentor Coeruleus	SteCoe_21527	1.9792598779469045e-32
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00279750(coding)
ATGTAAAATAAACAAGATTACGATACTTTACTTAAGTTTTTGCTTATTGGTGATTCAGGT
GTTGGAAAAACCTGTTTCCTAGTCAACTATTGCGAAGGTACTTTTACTAGCGCTCACTTA
TCAACAATTGGCATTGATTACAAACTTAAATATGAAGATATTGATGGAAAGCGCGTTAAG
CTCTAAATTTGGGATACTGCAGGCCAAGAAAGATTCAGAACAATTACTTAAAATTATTAC
AAAGGTGCTATGGGTATTATTCTAGCTTATAGTGTAACAGACCCCAATTCTTTCAAGAAT
ATTGCAGATTGGATGAAGTAAATTAATGAACGTGCAGATCCAAATGTTAAAAAGATTATT
ATAGCCACAAAAATTGATATGAAGGATTAAAGAAAAGTCTCTACTCGTGAAGGAGAAGAA
CTTGCTGATAGATATGGTGTAAAATTCTTTGAAACTTCAGCTAAGGAAGGCGTTAATATT
TCCGAAGCTTTCAAGTGTATTGCCCGTTAAACATTAGAATCAATGGACACATCTACTAAA
GATTAGTTTAAAATTAATTACAAACCTAATAATCCTCAACCTAATAAAAAAGATGGAAAA
GATGGAAAATGTTGTTGA

>TTHERM_00279750(gene)
ATGTAAAATAAACAAGATTACGATACTTTACTTAAGTTTTTGCTTATTGGTGATTCAGGT
GTTGGAAAAACCTGTTTCCTAGTCAACTATTGCGAAGGTACTTTTACTAGCGCTCACTTA
TCAACAATTGGCATTGATTACAAACTTAAATATGAAGATATTGATGGAAAGCGCGTTAAG
CTCTAAATTTGGGATACTGCAGGCCAAGAAAGATTCAGAACAATTACTTAAAATTATTAC
AAAGGTGCTATGGGTATTATTCTAGCTTATAGTGTAACAGACCCCAATTCTTTCAAGAAT
ATTGCAGATTGGATGAAGTAAATTAATGAACGTGCAGATCCAAATGTTAAAAAGATTATT
ATAGCCACAAAAATTGATATGAAGGATTAAAGAAAAGTCTCTACTCGTGAAGGAGAAGAA
CTTGCTGATAGATATGGTGTAAAATTCTTTGAAACTTCAGCTAAGGAAGGCGTTAATATT
TCCGAAGCTTTCAAGTGTATTGCCCGTTAAACATTAGAATCAATGGACACATCTACTAAA
GATTAGTTTAAAATTAATTACAAACCTAATAATCCTCAACCTAATAAAAAAGATGGAAAA
GATGGAAAATGTTGTTGA

>TTHERM_00279750(protein)
MQNKQDYDTLLKFLLIGDSGVGKTCFLVNYCEGTFTSAHLSTIGIDYKLKYEDIDGKRVK
LQIWDTAGQERFRTITQNYYKGAMGIILAYSVTDPNSFKNIADWMKQINERADPNVKKII
IATKIDMKDQRKVSTREGEELADRYGVKFFETSAKEGVNISEAFKCIARQTLESMDTSTK
DQFKINYKPNNPQPNKKDGKDGKCC