Identifiers and Description

Gene Model Identifier

TTHERM_00310640

Standard Name

DES7 (C-7(8) sterol DESaturase 7)

Aliases

PreTt21365 | 29.m00326 | 3696.m00144

Description

DES7 Rieske-like [2Fe-2S] domain protein; Sterol-C7 desaturase, a Rieske-type oxygenase; catalyzes the introduction of a C-7(8) double bond into cholesterol and other sterols; Cholesterol 7-desaturase

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF00355 ) Rieske [2Fe-2S] domain
  • ( PF19298 ) 3-Ketosteroid 9alpha-hydroxylase C-terminal domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:25681633: Poklepovich TJ, Urtasun N, Miranda MV, Nusblat AD, Nudel CB (2015) Expression and functional characterization of a C-7 cholesterol desaturase from Tetrahymena thermophila in an insect cell line. Steroids 96( ):132-9

Sequences 

>TTHERM_00310640(coding)
ATGATTGAGTTCAACAAAGAATGTCTTATGGACATCCTTAAAAATCAAGATTACCATTTT
TATATGGTCATTCCTTTGATTTTCATAGGTCTCTACGCACTTTATATTAAAAAATTCAAA
TACTACAATCCTATTGAAAAGCAAGAATGGGATGATAGACGCTCTAACGTCAAGAGAGGT
AACCCACCTCCAAGCTATCCTAATGGTTGGTTCAGAGTTTGTCACAAAAATGAACTCTAA
ATTGGTCAATCTAAGTTCTTCAAGCTTAATGGTCGTCACATCACTGTTTTCCGCGGTGAA
GATGGTATCCCTTATGCTTTACATGCTTACTGCTCTCATATGGGTGCAAATCTCGGTATT
GGAGGTAAAGTTAAATGGAACTCTTGTATTGAATGTCCTTTCCATGGATGGTCTTTCGAC
GGTAAATCAGGTAAATGTGTTAACTCTGAACATTTAGATGAGAAGTAATGTACCCACCAC
ACCTATCACGACATCAAGAAAATGACCAAGGGTTCTGACAACAGATACATTAAAACATGC
GAATCTGGTTCTCCTTCCTAAATCTAAAAATTCCATGTCCGTCAATAAAACAATTTAATT
TATGTCTGGTTCCATGCTAAAAACGTCGACCCTTACTATGAACCTTTTGAAATTAATGAA
ATTCCTTATCTTGAAGATAGAGGTGAAACTGCCGACTATGTTAATTGCTAAATCCAAGAA
ATCCCTGAAAACGGAGCTGATTTCAAGCACTTTGAATACGTTCACTACGCTTGGATCGAA
ATACTTTTCCCATGGATTAAATTCAAGTGGGTTCCTAAGGATCGTAAACCAACTGATAAG
GACTTCGATGAAGTAATGAGAACTCACCCCAACAAAAAGGTTCAAGCCTTTTCAAACAAG
CTCTTCGACAAGTACACTAACGAATAAAATAAAACTCACATCAATAACCTCGTCTTGGAT
GCCTATCTTGTCTTCTTTGATAAATTTGAATTCTACATCTAAACTGCAACAGTCTTCTAA
TTAGGTTCCGGTACTGTATTTTTATTCTTGAAATTCCCCTTATGGGAAGCTGTTGTTGTC
TAGAGTGTTACTCCTGTTGGAAAGTTCAATTAACTTGTTCACCACAAGATGTACACTTCC
TGGTGGTTACCTTACTGGGTCTCTGCTTATCTCCTAGCTGGTTTTAGAAAGTAATTCATT
TCTGACAAAATTGTCTGGAATAACAAAATTTTTGCTGACAAGCTTACATACAATCCTAAA
GCTGTATTTGATGAGAGACTCCTCAACTGGAGAGAATGGTATTCTCAGTACTACGAAGGC
TGCGATGAATTCGAAAAGAACCAAGAAGCTTTTGACTGGTGA



>TTHERM_00310640(gene)
TCTAAGAAAAATTAAAAAGAAGTAAAGTACAAACTAATATCTTTTTAAGTTCTATCTATA
GGTTTAAAAGCACTAAGTAAATAGAAGAAGTTTATACTAAAATTAATTATAATTTGCCAT
AAATGATTGAGTTCAACAAAGAATGTCTTATGGACATCCTTAAAAATCAAGATTACCATT
TTTATATGGTCATTCCTTTGATTTTCATAGGTCTCTACGCACTTTATATTAAAAAATTCA
AATACTACAATCCTATTGAAAAGCAAGAATGGGATGATAGACGCTCTAACGTCAAGAGAG
GTAACCCACCTCCAAGCTATCCTAATGGTTGGTTCAGAGTTTGTCACAAAAATGAACTCT
AAATTGGTCAATCTAAGTTCTTCAAGCTTAATGGTCGTCACATCACTGTTTTCCGCGGTG
AAGATGGTATCCCTTATGCTTTACATGCTTACTGCTCTCATATGGGTGCAAATCTCGGTA
TTGGAGGTAAAGTTAAATGGAACTCTTGTATTGAATGTCCTTTCCATGGATGGTCTTTCG
ACGGTAAATCAGGTAAATGTGTTAACTCTGAACATTTAGATGAGAAGTAATGTACCCACC
ACACCTATCACGACATCAAGAAAATGACCAAGGGTTCTGACAACAGATACATTAAAACAT
GCGAATCTGGTTCTCCTTCCTAAATCTAAAAATTCCATGTCCGTCAATAAAACAATTTAA
TTTATGTCTGGTTCCATGCTAAAAACGTCGACCCTTACTATGAACCTTTTGAAATTAATG
AAATTCCTTATCTTGAAGATAGAGGTGAAACTGCCGACTATGTTAATTGCTAAATCCAAG
AAATCCCTGAAAACGGAGCTGATTTCAAGCACTTTGAATACGTTCACTACGCTTGGATCG
AAATACTTTTCCCATGGATTAAATTCAAGTGGGTTCCTAAGGATCGTAAACCAACTGATA
AGGACTTCGATGAAGTAATGAGAACTCACCCCAACAAAAAGGTTCAAGCCTTTTCAAACA
AGCTCTTCGACAAGTACACTAACGAATAAAATAAAACTCACATCAATAACCTCGTCTTGG
ATGCCTATCTTGTCTTCTTTGATAAATTTGAATTCTACATCTAAACTGCAACAGTCTTCT
AATTAGGTTCCGGTACTGTATTTTTATTCTTGAAATTCCCCTTATGGGAAGCTGTTGTTG
TCTAGAGTGTTACTCCTGTTGGAAAGTTCAATTAACTTGTTCACCACAAGATGTACACTT
CCTGGTGGTTACCTTACTGGGTCTCTGCTTATCTCCTAGCTGGTTTTAGAAAGTAATTCA
TTTCTGACAAAATTGTCTGGAATAACAAAATTTTTGCTGACAAGCTTACATACAATCCTA
AAGCTGTATTTGATGAGAGACTCCTCAACTGGAGAGAATGGTATTCTCAGTACTACGAAG
GCTGCGATGAATTCGAAAAGAACCAAGAAGCTTTTGACTGGTGATTTAGATGTAGCATTA
ATCAATCGTTTGTTATATTTGACTTCACTGAATATTTAGTTTAAATATATAAATAAATAT
AATCCATGCATTATTATAAAATATTTTTCAAATACAATCTATAAATAAAAAATAGATTTC
TTTTTAAAGTAATAAAAATAAATTTCATAAATACATGTAATTAAATATTTAGTTAGTTAG
TTAGCTAGTTAGAAATTTTTAATTTTTTCTTTTAATCAAAATTAAAATTGATGTCAATTT
TGCATGCATGTGAATACTGTAAACCCATTAAAAAATTCATTTACTTTATACTTTCACTAA
ATACCATAAAATATTAAGTAAATTTTATCTTAAATCTAATTAATTCTTAGTTTTCAAAAT




>TTHERM_00310640(protein)
MIEFNKECLMDILKNQDYHFYMVIPLIFIGLYALYIKKFKYYNPIEKQEWDDRRSNVKRG
NPPPSYPNGWFRVCHKNELQIGQSKFFKLNGRHITVFRGEDGIPYALHAYCSHMGANLGI
GGKVKWNSCIECPFHGWSFDGKSGKCVNSEHLDEKQCTHHTYHDIKKMTKGSDNRYIKTC
ESGSPSQIQKFHVRQQNNLIYVWFHAKNVDPYYEPFEINEIPYLEDRGETADYVNCQIQE
IPENGADFKHFEYVHYAWIEILFPWIKFKWVPKDRKPTDKDFDEVMRTHPNKKVQAFSNK
LFDKYTNEQNKTHINNLVLDAYLVFFDKFEFYIQTATVFQLGSGTVFLFLKFPLWEAVVV
QSVTPVGKFNQLVHHKMYTSWWLPYWVSAYLLAGFRKQFISDKIVWNNKIFADKLTYNPK
AVFDERLLNWREWYSQYYEGCDEFEKNQEAFDW